Best TWAS P=4.75e-12 · Best GWAS P=1.3e-11 conditioned to 2.51e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | AFF3 | 0.14 | 0.06 | lasso | 5 | 0.07 | 1.2e-04 | -6.7 | -6.9 | 4.7e-12 | -0.43 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | LONRF2 | 0.05 | 0.03 | lasso | 2 | 0.02 | 9.3e-03 | 4.8 | -5.6 | 2.3e-08 | -0.74 | 0.09 | 0.75 | FALSE |
| 3 | GTEx | Thyroid | CHST10 | 0.05 | 0.05 | lasso | 5 | 0.03 | 2.6e-03 | -4.8 | -5.8 | 5.4e-09 | -0.75 | 0.37 | 0.43 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LONRF2 | 0.06 | 0.04 | blup | 69 | 0.04 | 3.4e-05 | 4.6 | -5.9 | 3.7e-09 | -0.72 | 0.67 | 0.31 | FALSE |