Best TWAS P=6.78e-11 · Best GWAS P=3.43e-12 conditioned to 0.609
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | GRB14 | 0.14 | 0.09 | lasso | 7 | 0.06 | 0.00016 | 6.4 | -6.5 | 6.8e-11 | -0.65 | 0.08 | 0.83 | TRUE |
| 2 | GTEx | Thyroid | COBLL1 | 0.07 | 0.05 | lasso | 3 | 0.05 | 0.00015 | -5.0 | 5.3 | 1.2e-07 | 0.46 | 0.56 | 0.25 | TRUE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | GRB14 | 0.09 | 0.01 | blup | 82 | 0.03 | 0.00464 | 5.4 | -5.7 | 1.2e-08 | -0.57 | 0.02 | 0.64 | FALSE |