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chr7:91,142,400-93,160,671

Best TWAS P=2.49e-49 · Best GWAS P=5.91e-44 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CDK6	0.12	0.10	lasso	2	0.10	1.9e-12	13.71	13.7	7.8e-43	0.89	0.01	0.99	FALSE
2	GTEx	Adipose Visceral Omentum	GATAD1	0.12	0.08	lasso	5	0.06	7.5e-04	6.63	-6.6	3.3e-11	-0.51	0.80	0.08	FALSE
3	GTEx	Adrenal Gland	GATAD1	0.40	0.22	lasso	7	0.25	2.0e-09	6.63	-7.4	1.8e-13	-0.57	0.66	0.10	FALSE
4	GTEx	Artery Aorta	KRIT1	0.15	0.00	enet	24	0.03	1.3e-02	0.55	-6.2	5.1e-10	-0.27	0.12	0.06	FALSE
5	GTEx	Artery Aorta	GATAD1	0.09	0.08	enet	4	0.07	7.4e-05	6.63	-6.6	3.7e-11	-0.49	0.52	0.06	FALSE
6	GTEx	Artery Coronary	GATAD1	0.12	0.15	lasso	3	0.12	8.0e-05	6.75	-7.0	2.7e-12	-0.54	0.18	0.21	FALSE
7	GTEx	Artery Tibial	GATAD1	0.14	0.04	enet	17	0.04	4.1e-04	6.63	-6.7	2.2e-11	-0.45	0.70	0.11	FALSE
8	GTEx	Artery Tibial	AC007566.10	0.13	0.04	lasso	5	0.00	3.1e-01	5.64	-6.3	2.8e-10	-0.10	0.08	0.04	FALSE
9	GTEx	Brain Caudate basal ganglia	GATAD1	0.21	0.09	lasso	4	0.08	2.3e-03	5.11	-7.6	2.8e-14	-0.56	0.07	0.35	FALSE
10	GTEx	Breast Mammary Tissue (Female)	AC007566.10	0.04	-0.01	lasso	2	0.01	2.0e-01	1.26	-6.8	1.2e-11	-0.32	0.03	0.21	FALSE
11	GTEx	Cells Transformed fibroblasts	GATAD1	0.23	0.20	lasso	4	0.22	1.4e-16	6.63	-8.9	4.3e-19	-0.69	0.97	0.03	FALSE
12	GTEx	Colon Transverse	GATAD1	0.13	0.00	enet	16	0.05	3.0e-03	6.63	-7.6	3.7e-14	-0.52	0.20	0.18	FALSE
13	GTEx	Esophagus Mucosa	GATAD1	0.16	0.05	enet	16	0.08	7.3e-06	6.63	-7.0	2.2e-12	-0.46	0.77	0.11	FALSE
14	GTEx	Esophagus Muscularis	GATAD1	0.18	0.10	enet	33	0.13	1.6e-08	6.63	-5.5	2.8e-08	-0.38	0.97	0.00	FALSE
15	GTEx	Esophagus Muscularis	FAM133B	0.07	0.01	enet	2	0.01	1.2e-01	-9.27	-9.3	2.0e-20	-0.55	0.06	0.41	FALSE
16	GTEx	Lung	GATAD1	0.15	0.12	lasso	2	0.11	1.1e-08	6.63	-6.6	3.8e-11	-0.53	0.99	0.00	FALSE
17	GTEx	Muscle Skeletal	PEX1	0.06	0.03	lasso	5	0.02	2.7e-03	5.51	6.0	2.7e-09	0.42	0.49	0.21	FALSE
18	GTEx	Muscle Skeletal	GATAD1	0.05	0.00	enet	13	0.01	2.4e-02	2.79	-6.6	4.7e-11	-0.44	0.47	0.04	FALSE
19	GTEx	Pancreas	GATAD1	0.12	0.13	lasso	2	0.14	2.0e-06	6.63	-5.9	2.9e-09	-0.49	0.14	0.57	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	GATAD1	0.22	0.27	lasso	4	0.26	1.1e-14	6.63	-6.8	1.2e-11	-0.53	1.00	0.00	FALSE
21	GTEx	Skin Sun Exposed Lower leg	PEX1	0.18	0.06	enet	41	0.03	1.5e-03	-7.49	-7.8	7.0e-15	-0.44	0.20	0.16	FALSE
22	GTEx	Skin Sun Exposed Lower leg	GATAD1	0.30	0.10	enet	14	0.16	7.0e-13	6.63	-6.6	3.5e-11	-0.44	1.00	0.00	FALSE
23	GTEx	Spleen	PEX1	0.18	0.00	enet	38	0.05	2.4e-02	3.29	-7.0	2.5e-12	-0.38	0.08	0.08	FALSE
24	GTEx	Stomach	GATAD1	0.30	0.13	lasso	5	0.15	8.6e-08	6.63	-6.7	1.7e-11	-0.52	0.98	0.00	FALSE
25	GTEx	Testis	CDK6	0.10	0.10	lasso	3	0.09	8.0e-05	13.90	-14.8	2.5e-49	-0.96	0.01	0.98	TRUE
26	GTEx	Thyroid	GATAD1	0.18	0.06	lasso	4	0.06	3.3e-05	6.63	-6.5	9.0e-11	-0.48	0.95	0.03	FALSE
27	ROSMAP	Brain Pre-frontal Cortex	KRIT1	0.04	0.03	bslmm	311	0.01	9.0e-03	3.29	6.6	4.5e-11	0.51	0.75	0.05	FALSE
28	ROSMAP	Brain Pre-frontal Cortex	GATAD1	0.17	0.15	lasso	4	0.16	6.0e-20	6.64	-6.7	2.0e-11	-0.51	1.00	0.00	FALSE
29	YFS	Blood	GATAD1	0.01	0.01	blup	297	0.01	5.1e-04	6.63	-8.7	2.4e-18	-0.53	0.74	0.09	FALSE
30	The Cancer Genome Atlas	Breast Invasive Carcinoma	GATAD1	0.06	0.04	lasso	6	0.04	2.2e-09	6.38	-6.0	2.4e-09	-0.40	0.52	0.48	FALSE
31	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GATAD1	0.04	0.04	lasso	2	0.03	2.8e-04	6.38	-6.2	7.8e-10	-0.47	0.13	0.23	FALSE