Best TWAS P=3.78e-09 · Best GWAS P=6.03e-09 conditioned to 0.102
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | PTPRJ | 0.05 | 0.05 | lasso | 2 | 0.04 | 3.9e-04 | 5.5 | 5.3 | 1.0e-07 | 0.59 | 0.01 | 0.97 | FALSE |
| 2 | GTEx | Prostate | PSMC3 | 0.21 | 0.10 | lasso | 6 | 0.20 | 7.9e-06 | 4.4 | -5.4 | 8.5e-08 | -0.56 | 0.03 | 0.47 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | LRP4 | 0.13 | 0.00 | lasso | 7 | 0.02 | 3.5e-02 | 4.1 | 5.2 | 2.4e-07 | 0.53 | 0.02 | 0.31 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | CELF1 | 0.03 | 0.01 | bslmm | 289 | 0.01 | 2.9e-02 | 4.8 | 5.9 | 3.8e-09 | 0.83 | 0.03 | 0.85 | TRUE |