Best TWAS P=2.89e-10 · Best GWAS P=7.08e-11 conditioned to 3.2e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | NFATC3 | 0.04 | 0.01 | lasso | 4 | 0.01 | 4.1e-02 | 5.7 | -5.8 | 5.2e-09 | -0.32 | 0.19 | 0.42 | TRUE |
| 2 | GTEx | Thyroid | PLA2G15 | 0.06 | 0.04 | enet | 5 | 0.04 | 5.7e-04 | 5.8 | 5.7 | 1.2e-08 | 0.38 | 0.21 | 0.73 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NFATC3 | 0.11 | 0.04 | enet | 4 | 0.04 | 2.8e-05 | 5.7 | -5.6 | 2.0e-08 | -0.36 | 0.01 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | AGRP | 0.11 | 0.01 | enet | 6 | 0.07 | 2.5e-05 | 5.4 | -6.3 | 2.9e-10 | -0.12 | 0.00 | 0.72 | TRUE |