Best TWAS P=3.37e-16 · Best GWAS P=2.03e-25 conditioned to 9.78e-13
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FNDC3B | 0.07 | 0.06 | enet | 8 | 0.05 | 3.2e-07 | -8.6 | 8.2 | 3.4e-16 | 0.04 | 0.97 | 0.00 | TRUE |
| 2 | YFS | Blood | TNFSF10 | 0.09 | 0.04 | bslmm | 462 | 0.08 | 1.6e-24 | 6.5 | 6.1 | 1.2e-09 | 0.38 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FNDC3B | 0.07 | 0.02 | enet | 6 | 0.02 | 3.9e-03 | 7.3 | -7.4 | 1.2e-13 | -0.83 | 0.01 | 0.98 | TRUE |