Best TWAS P=3.48e-09 · Best GWAS P=2.32e-09 conditioned to 0.245
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | SLC38A9 | 0.26 | 0.13 | lasso | 4 | 0.10 | 7.4e-04 | 5.7 | 5.6 | 2.7e-08 | 0.84 | 0.03 | 0.94 | FALSE |
| 2 | GTEx | Brain Hippocampus | GZMA | 0.32 | 0.00 | lasso | 6 | 0.02 | 1.3e-01 | 4.2 | 5.7 | 1.4e-08 | 0.37 | 0.04 | 0.56 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Female) | GPX8 | 0.04 | 0.00 | lasso | 2 | 0.03 | 5.0e-02 | 5.6 | -5.6 | 1.9e-08 | -0.89 | 0.05 | 0.25 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PPAP2A | 0.06 | 0.03 | lasso | 1 | 0.03 | 1.1e-06 | 5.5 | -5.5 | 3.9e-08 | -0.78 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC38A9 | 0.04 | 0.02 | enet | 7 | 0.03 | 6.6e-03 | 5.5 | 5.5 | 3.0e-08 | 0.86 | 0.02 | 0.76 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | SLC38A9 | 0.03 | 0.04 | blup | 52 | 0.04 | 2.0e-04 | 5.7 | 5.9 | 3.5e-09 | 0.95 | 0.02 | 0.97 | TRUE |