Best TWAS P=7.19e-11 · Best GWAS P=5.57e-32 conditioned to 2.61e-18
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | SSR1 | 0.20 | 0.03 | bslmm | 635 | 0.14 | 2.3e-16 | -2.9 | -5.1 | 3.1e-07 | -0.01 | 0.92 | 0.0 | TRUE |
2 | GTEx | Stomach | RIOK1 | 0.23 | 0.06 | enet | 28 | 0.07 | 2.6e-04 | -1.2 | 5.2 | 1.9e-07 | 0.22 | 0.44 | 0.1 | TRUE |
3 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | BMP6 | 0.29 | 0.00 | blup | 162 | 0.03 | 5.6e-02 | 1.2 | 6.5 | 7.2e-11 | 0.49 | 0.02 | 0.2 | TRUE |