[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr10:76,459,669-80,383,574

Best TWAS P=3.96e-18 · Best GWAS P=1.44e-17 conditioned to 0.566

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DLG5	0.10	0.07	lasso	5	0.06	3.3e-08	-5.5	-5.2	1.7e-07	0.02	0.08	0.92	FALSE
2	CommonMind	Brain Pre-frontal Cortex	ZNF503	0.08	0.00	blup	366	0.03	2.5e-04	6.7	5.6	1.9e-08	0.17	0.36	0.02	TRUE
3	GTEx	Adipose Subcutaneous	C10orf11	0.24	0.21	lasso	9	0.20	3.3e-16	7.5	-8.2	2.3e-16	-0.91	0.04	0.96	FALSE
4	GTEx	Adipose Subcutaneous	DLG5	0.39	0.40	lasso	12	0.43	1.9e-38	-5.5	-5.5	4.7e-08	0.02	0.19	0.81	FALSE
5	GTEx	Adipose Subcutaneous	RP13-39P12.3	0.31	0.27	lasso	12	0.34	1.1e-28	-5.3	-5.2	1.6e-07	0.01	0.22	0.78	FALSE
6	GTEx	Adipose Visceral Omentum	C10orf11	0.40	0.32	enet	11	0.27	2.2e-14	7.5	-8.5	2.3e-17	-0.93	0.02	0.98	FALSE
7	GTEx	Adipose Visceral Omentum	DLG5	0.26	0.23	lasso	8	0.21	5.7e-11	-5.3	-5.4	7.9e-08	0.03	0.22	0.77	FALSE
8	GTEx	Adrenal Gland	C10orf11	0.24	0.22	enet	21	0.18	5.8e-07	7.5	-7.4	1.2e-13	-0.86	0.02	0.98	FALSE
9	GTEx	Adrenal Gland	DLG5	0.22	0.14	lasso	6	0.11	8.5e-05	-5.3	-5.7	1.5e-08	0.03	0.18	0.70	FALSE
10	GTEx	Artery Aorta	DLG5	0.26	0.19	enet	10	0.22	2.6e-12	-5.2	-5.8	6.9e-09	0.02	0.18	0.82	FALSE
11	GTEx	Artery Aorta	RP13-39P12.3	0.14	0.13	enet	9	0.12	2.2e-07	-5.2	-5.6	2.2e-08	0.04	0.06	0.93	FALSE
12	GTEx	Artery Coronary	DLG5	0.33	0.25	lasso	4	0.27	1.4e-09	-5.5	-5.5	3.7e-08	0.01	0.14	0.85	FALSE
13	GTEx	Artery Coronary	RP13-39P12.3	0.21	0.03	lasso	4	0.09	7.2e-04	-5.5	-5.2	1.8e-07	0.01	0.16	0.65	FALSE
14	GTEx	Artery Tibial	DLG5	0.24	0.18	lasso	5	0.18	9.7e-14	-5.4	-5.3	1.1e-07	0.03	0.24	0.76	FALSE
15	GTEx	Brain Cerebellum	DLG5	0.36	0.28	lasso	7	0.36	1.6e-11	-5.5	-5.2	1.8e-07	0.01	0.22	0.77	FALSE
16	GTEx	Breast Mammary Tissue	DLG5	0.15	0.09	lasso	7	0.08	6.7e-05	-5.3	-5.3	1.2e-07	0.04	0.16	0.66	FALSE
17	GTEx	Cells Transformed fibroblasts	DLG5	0.25	0.18	lasso	11	0.16	2.0e-12	-5.4	-5.7	1.3e-08	0.03	0.12	0.88	FALSE
18	GTEx	Cells Transformed fibroblasts	RP13-39P12.3	0.19	0.13	lasso	7	0.15	4.5e-11	-5.4	-5.5	3.2e-08	0.01	0.18	0.82	FALSE
19	GTEx	Colon Transverse	DLG5	0.23	0.17	lasso	8	0.19	1.4e-09	-5.5	-5.5	3.9e-08	0.02	0.20	0.80	FALSE
20	GTEx	Esophagus Gastroesophageal Junction	DLG5	0.27	0.03	enet	13	0.06	3.9e-03	-6.4	-5.6	2.4e-08	-0.05	0.00	0.98	FALSE
21	GTEx	Esophagus Mucosa	DLG5	0.21	0.16	lasso	5	0.18	5.2e-12	-5.5	-5.4	6.9e-08	0.01	0.22	0.78	FALSE
22	GTEx	Esophagus Muscularis	C10orf11	0.45	0.39	enet	42	0.38	5.1e-24	7.5	-8.7	4.0e-18	-0.86	0.18	0.82	TRUE
23	GTEx	Heart Atrial Appendage	DLG5	0.32	0.23	lasso	4	0.24	3.9e-11	-5.3	-5.4	6.4e-08	0.03	0.23	0.77	FALSE
24	GTEx	Heart Left Ventricle	DLG5	0.13	0.10	lasso	4	0.09	1.2e-05	-5.3	-5.3	9.3e-08	0.03	0.11	0.88	FALSE
25	GTEx	Liver	DLG5	0.42	0.31	lasso	5	0.28	2.1e-08	-5.4	-5.3	1.1e-07	0.04	0.03	0.97	FALSE
26	GTEx	Lung	C10orf11	0.30	0.26	lasso	5	0.24	2.0e-18	7.5	-8.2	2.7e-16	-0.91	0.04	0.96	FALSE
27	GTEx	Lung	DLG5	0.41	0.38	lasso	8	0.37	7.9e-30	-5.3	-5.5	4.0e-08	0.03	0.25	0.75	FALSE
28	GTEx	Nerve Tibial	DLG5	0.51	0.44	lasso	6	0.50	1.4e-39	-5.4	-5.8	5.8e-09	0.02	0.20	0.80	TRUE
29	GTEx	Nerve Tibial	RP13-39P12.3	0.31	0.25	lasso	7	0.36	1.3e-26	-5.3	-5.6	2.8e-08	0.01	0.16	0.84	FALSE
30	GTEx	Ovary	DLG5	0.62	0.38	lasso	6	0.40	5.3e-11	-5.4	-5.8	9.1e-09	0.02	0.24	0.75	FALSE
31	GTEx	Ovary	RP13-39P12.3	0.42	0.29	lasso	5	0.33	7.5e-09	-5.4	-5.7	1.6e-08	0.02	0.23	0.71	FALSE
32	GTEx	Pancreas	DLG5	0.39	0.43	enet	11	0.44	3.5e-20	-5.4	-5.3	8.7e-08	0.04	0.22	0.78	FALSE
33	GTEx	Pancreas	RP13-39P12.3	0.20	0.24	lasso	3	0.23	3.8e-10	-5.3	-5.4	8.4e-08	0.03	0.24	0.76	FALSE
34	GTEx	Pituitary	DLG5	0.45	0.36	lasso	11	0.31	1.9e-08	-5.4	-5.6	2.1e-08	0.03	0.06	0.94	FALSE
35	GTEx	Pituitary	RP13-39P12.3	0.38	0.22	lasso	11	0.17	3.8e-05	-5.4	-5.6	2.0e-08	0.03	0.03	0.93	FALSE
36	GTEx	Skin Sun Exposed Lower leg	DLG5	0.12	0.06	lasso	4	0.06	4.9e-06	-5.3	-5.4	7.5e-08	0.02	0.17	0.82	FALSE
37	GTEx	Spleen	DLG5	0.51	0.46	lasso	4	0.44	1.1e-12	-5.4	-5.4	5.3e-08	0.02	0.20	0.79	FALSE
38	GTEx	Spleen	RP13-39P12.3	0.38	0.34	lasso	2	0.35	8.8e-10	-5.4	-5.4	7.3e-08	0.01	0.17	0.81	FALSE
39	GTEx	Stomach	DLG5	0.20	0.12	lasso	7	0.08	1.3e-04	-5.4	-5.4	6.9e-08	0.03	0.18	0.78	FALSE
40	GTEx	Thyroid	C10orf11	0.38	0.21	lasso	9	0.25	6.7e-19	7.1	-8.4	6.5e-17	-0.86	0.09	0.91	FALSE
41	GTEx	Thyroid	DLG5	0.39	0.43	lasso	5	0.43	1.5e-35	-5.3	-5.3	9.7e-08	0.04	0.27	0.73	FALSE
42	GTEx	Thyroid	RP13-39P12.3	0.28	0.30	lasso	8	0.29	3.3e-22	-5.3	-5.4	6.0e-08	0.03	0.26	0.73	FALSE
43	METSIM	Adipose	C10orf11	0.11	0.10	enet	14	0.10	1.1e-14	7.1	-7.4	1.8e-13	-0.83	0.44	0.56	FALSE
44	METSIM	Adipose	DLG5	0.18	0.19	lasso	11	0.22	2.2e-32	-5.3	-5.2	2.3e-07	0.01	0.26	0.74	FALSE
45	ROSMAP	Brain Pre-frontal Cortex	ZNF503	0.05	0.04	bslmm	342	0.04	2.2e-06	6.3	5.5	3.6e-08	0.12	0.96	0.00	FALSE
46	ROSMAP	Brain Pre-frontal Cortex	ZNF503-AS2	0.07	0.06	lasso	2	0.06	2.2e-08	6.3	6.5	6.4e-11	0.29	1.00	0.00	FALSE