[Hub]/) : Traits : Arm predicted mass (right) :

chr10:76,459,669-80,383,574

Best TWAS P=3.96e-18 · Best GWAS P=1.44e-17 conditioned to 0.566

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DLG5 0.10 0.07 lasso 5 0.06 3.3e-08 -5.5 -5.2 1.7e-07 0.02 0.08 0.92 FALSE
2 CommonMind Brain Pre-frontal Cortex ZNF503 0.08 0.00 blup 366 0.03 2.5e-04 6.7 5.6 1.9e-08 0.17 0.36 0.02 TRUE
3 GTEx Adipose Subcutaneous C10orf11 0.24 0.21 lasso 9 0.20 3.3e-16 7.5 -8.2 2.3e-16 -0.91 0.04 0.96 FALSE
4 GTEx Adipose Subcutaneous DLG5 0.39 0.40 lasso 12 0.43 1.9e-38 -5.5 -5.5 4.7e-08 0.02 0.19 0.81 FALSE
5 GTEx Adipose Subcutaneous RP13-39P12.3 0.31 0.27 lasso 12 0.34 1.1e-28 -5.3 -5.2 1.6e-07 0.01 0.22 0.78 FALSE
6 GTEx Adipose Visceral Omentum C10orf11 0.40 0.32 enet 11 0.27 2.2e-14 7.5 -8.5 2.3e-17 -0.93 0.02 0.98 FALSE
7 GTEx Adipose Visceral Omentum DLG5 0.26 0.23 lasso 8 0.21 5.7e-11 -5.3 -5.4 7.9e-08 0.03 0.22 0.77 FALSE
8 GTEx Adrenal Gland C10orf11 0.24 0.22 enet 21 0.18 5.8e-07 7.5 -7.4 1.2e-13 -0.86 0.02 0.98 FALSE
9 GTEx Adrenal Gland DLG5 0.22 0.14 lasso 6 0.11 8.5e-05 -5.3 -5.7 1.5e-08 0.03 0.18 0.70 FALSE
10 GTEx Artery Aorta DLG5 0.26 0.19 enet 10 0.22 2.6e-12 -5.2 -5.8 6.9e-09 0.02 0.18 0.82 FALSE
11 GTEx Artery Aorta RP13-39P12.3 0.14 0.13 enet 9 0.12 2.2e-07 -5.2 -5.6 2.2e-08 0.04 0.06 0.93 FALSE
12 GTEx Artery Coronary DLG5 0.33 0.25 lasso 4 0.27 1.4e-09 -5.5 -5.5 3.7e-08 0.01 0.14 0.85 FALSE
13 GTEx Artery Coronary RP13-39P12.3 0.21 0.03 lasso 4 0.09 7.2e-04 -5.5 -5.2 1.8e-07 0.01 0.16 0.65 FALSE
14 GTEx Artery Tibial DLG5 0.24 0.18 lasso 5 0.18 9.7e-14 -5.4 -5.3 1.1e-07 0.03 0.24 0.76 FALSE
15 GTEx Brain Cerebellum DLG5 0.36 0.28 lasso 7 0.36 1.6e-11 -5.5 -5.2 1.8e-07 0.01 0.22 0.77 FALSE
16 GTEx Breast Mammary Tissue DLG5 0.15 0.09 lasso 7 0.08 6.7e-05 -5.3 -5.3 1.2e-07 0.04 0.16 0.66 FALSE
17 GTEx Cells Transformed fibroblasts DLG5 0.25 0.18 lasso 11 0.16 2.0e-12 -5.4 -5.7 1.3e-08 0.03 0.12 0.88 FALSE
18 GTEx Cells Transformed fibroblasts RP13-39P12.3 0.19 0.13 lasso 7 0.15 4.5e-11 -5.4 -5.5 3.2e-08 0.01 0.18 0.82 FALSE
19 GTEx Colon Transverse DLG5 0.23 0.17 lasso 8 0.19 1.4e-09 -5.5 -5.5 3.9e-08 0.02 0.20 0.80 FALSE
20 GTEx Esophagus Gastroesophageal Junction DLG5 0.27 0.03 enet 13 0.06 3.9e-03 -6.4 -5.6 2.4e-08 -0.05 0.00 0.98 FALSE
21 GTEx Esophagus Mucosa DLG5 0.21 0.16 lasso 5 0.18 5.2e-12 -5.5 -5.4 6.9e-08 0.01 0.22 0.78 FALSE
22 GTEx Esophagus Muscularis C10orf11 0.45 0.39 enet 42 0.38 5.1e-24 7.5 -8.7 4.0e-18 -0.86 0.18 0.82 TRUE
23 GTEx Heart Atrial Appendage DLG5 0.32 0.23 lasso 4 0.24 3.9e-11 -5.3 -5.4 6.4e-08 0.03 0.23 0.77 FALSE
24 GTEx Heart Left Ventricle DLG5 0.13 0.10 lasso 4 0.09 1.2e-05 -5.3 -5.3 9.3e-08 0.03 0.11 0.88 FALSE
25 GTEx Liver DLG5 0.42 0.31 lasso 5 0.28 2.1e-08 -5.4 -5.3 1.1e-07 0.04 0.03 0.97 FALSE
26 GTEx Lung C10orf11 0.30 0.26 lasso 5 0.24 2.0e-18 7.5 -8.2 2.7e-16 -0.91 0.04 0.96 FALSE
27 GTEx Lung DLG5 0.41 0.38 lasso 8 0.37 7.9e-30 -5.3 -5.5 4.0e-08 0.03 0.25 0.75 FALSE
28 GTEx Nerve Tibial DLG5 0.51 0.44 lasso 6 0.50 1.4e-39 -5.4 -5.8 5.8e-09 0.02 0.20 0.80 TRUE
29 GTEx Nerve Tibial RP13-39P12.3 0.31 0.25 lasso 7 0.36 1.3e-26 -5.3 -5.6 2.8e-08 0.01 0.16 0.84 FALSE
30 GTEx Ovary DLG5 0.62 0.38 lasso 6 0.40 5.3e-11 -5.4 -5.8 9.1e-09 0.02 0.24 0.75 FALSE
31 GTEx Ovary RP13-39P12.3 0.42 0.29 lasso 5 0.33 7.5e-09 -5.4 -5.7 1.6e-08 0.02 0.23 0.71 FALSE
32 GTEx Pancreas DLG5 0.39 0.43 enet 11 0.44 3.5e-20 -5.4 -5.3 8.7e-08 0.04 0.22 0.78 FALSE
33 GTEx Pancreas RP13-39P12.3 0.20 0.24 lasso 3 0.23 3.8e-10 -5.3 -5.4 8.4e-08 0.03 0.24 0.76 FALSE
34 GTEx Pituitary DLG5 0.45 0.36 lasso 11 0.31 1.9e-08 -5.4 -5.6 2.1e-08 0.03 0.06 0.94 FALSE
35 GTEx Pituitary RP13-39P12.3 0.38 0.22 lasso 11 0.17 3.8e-05 -5.4 -5.6 2.0e-08 0.03 0.03 0.93 FALSE
36 GTEx Skin Sun Exposed Lower leg DLG5 0.12 0.06 lasso 4 0.06 4.9e-06 -5.3 -5.4 7.5e-08 0.02 0.17 0.82 FALSE
37 GTEx Spleen DLG5 0.51 0.46 lasso 4 0.44 1.1e-12 -5.4 -5.4 5.3e-08 0.02 0.20 0.79 FALSE
38 GTEx Spleen RP13-39P12.3 0.38 0.34 lasso 2 0.35 8.8e-10 -5.4 -5.4 7.3e-08 0.01 0.17 0.81 FALSE
39 GTEx Stomach DLG5 0.20 0.12 lasso 7 0.08 1.3e-04 -5.4 -5.4 6.9e-08 0.03 0.18 0.78 FALSE
40 GTEx Thyroid C10orf11 0.38 0.21 lasso 9 0.25 6.7e-19 7.1 -8.4 6.5e-17 -0.86 0.09 0.91 FALSE
41 GTEx Thyroid DLG5 0.39 0.43 lasso 5 0.43 1.5e-35 -5.3 -5.3 9.7e-08 0.04 0.27 0.73 FALSE
42 GTEx Thyroid RP13-39P12.3 0.28 0.30 lasso 8 0.29 3.3e-22 -5.3 -5.4 6.0e-08 0.03 0.26 0.73 FALSE
43 METSIM Adipose C10orf11 0.11 0.10 enet 14 0.10 1.1e-14 7.1 -7.4 1.8e-13 -0.83 0.44 0.56 FALSE
44 METSIM Adipose DLG5 0.18 0.19 lasso 11 0.22 2.2e-32 -5.3 -5.2 2.3e-07 0.01 0.26 0.74 FALSE
45 ROSMAP Brain Pre-frontal Cortex ZNF503 0.05 0.04 bslmm 342 0.04 2.2e-06 6.3 5.5 3.6e-08 0.12 0.96 0.00 FALSE
46 ROSMAP Brain Pre-frontal Cortex ZNF503-AS2 0.07 0.06 lasso 2 0.06 2.2e-08 6.3 6.5 6.4e-11 0.29 1.00 0.00 FALSE