[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr17:75,977,988-79,637,565

Best TWAS P=2.17e-10 · Best GWAS P=2.42e-16 conditioned to 2.49e-17

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex USP36 0.14 0.13 lasso 3 0.13 1.7e-15 5.5 -5.6 1.8e-08 0.02 0.08 0.92 FALSE
2 GTEx Brain Cerebellar Hemisphere USP36 0.50 0.16 enet 20 0.07 5.7e-03 5.5 -5.8 5.2e-09 -0.03 0.06 0.86 FALSE
3 GTEx Brain Nucleus accumbens basal ganglia USP36 0.36 0.23 lasso 5 0.20 4.8e-06 6.3 -6.3 2.2e-10 0.02 0.02 0.98 TRUE
4 GTEx Cells Transformed fibroblasts CBX8 0.21 0.10 lasso 3 0.08 1.4e-06 -5.4 5.4 6.6e-08 0.05 0.00 1.00 FALSE
5 GTEx Esophagus Mucosa USP36 0.11 0.04 enet 13 0.06 1.1e-04 5.8 -5.4 6.3e-08 0.04 0.03 0.96 FALSE
6 GTEx Esophagus Muscularis USP36 0.18 0.16 lasso 3 0.08 2.5e-05 5.5 5.2 2.0e-07 0.00 0.10 0.90 FALSE
7 GTEx Lung CBX8 0.28 0.19 enet 24 0.18 1.4e-13 -5.6 5.5 3.7e-08 0.04 0.00 1.00 FALSE
8 GTEx Muscle Skeletal CYTH1 0.13 0.12 lasso 3 0.13 2.5e-12 5.7 5.6 2.1e-08 -0.02 0.12 0.88 FALSE
9 GTEx Muscle Skeletal RPTOR 0.14 0.05 enet 27 0.09 8.4e-09 -4.3 -5.6 2.2e-08 -0.02 0.98 0.00 TRUE
10 GTEx Nerve Tibial CBX8 0.16 0.14 lasso 4 0.14 5.3e-10 -5.4 5.6 2.8e-08 0.05 0.00 1.00 TRUE
11 GTEx Testis USP36 0.32 0.24 lasso 6 0.26 6.2e-12 4.9 -5.6 2.2e-08 0.03 0.14 0.86 FALSE
12 GTEx Thyroid USP36 0.21 0.15 enet 45 0.16 1.6e-12 5.4 -5.4 5.7e-08 0.05 0.32 0.68 FALSE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors USP36 0.10 0.02 lasso 4 0.05 6.6e-03 6.1 -5.1 2.9e-07 0.06 0.02 0.85 FALSE