[Hub]/) : Traits : Arm fat percentage (left) :

chr15:40,828,922-42,468,786

Best TWAS P=5.61e-08 · Best GWAS P=7.57e-08 conditioned to 0.365

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Coronary OIP5-AS1 0.12 0.13 lasso 2 0.14 2.3e-05 5.2 5.2 1.8e-07 0.73 0.06 0.90 FALSE
2 GTEx Brain Caudate basal ganglia NUSAP1 0.31 0.38 lasso 9 0.40 1.1e-12 4.9 5.1 3.0e-07 0.77 0.06 0.94 FALSE
3 GTEx Brain Cerebellar Hemisphere NDUFAF1 0.20 0.23 lasso 6 0.22 2.2e-06 5.1 -5.3 1.5e-07 -0.76 0.05 0.94 FALSE
4 GTEx Brain Frontal Cortex BA9 NDUFAF1 0.55 0.37 lasso 8 0.40 1.6e-11 5.1 -5.2 1.7e-07 -0.73 0.05 0.95 FALSE
5 GTEx Brain Nucleus accumbens basal ganglia NDUFAF1 0.12 0.11 lasso 6 0.10 9.7e-04 5.1 -5.2 1.7e-07 -0.71 0.06 0.82 FALSE
6 GTEx Cells Transformed fibroblasts CHP1 0.13 0.11 lasso 6 0.11 2.1e-08 5.2 -5.4 5.6e-08 -0.93 0.04 0.96 TRUE
7 GTEx Cells Transformed fibroblasts OIP5-AS1 0.28 0.32 lasso 2 0.32 3.5e-24 5.1 5.2 2.2e-07 0.72 0.03 0.96 FALSE
8 GTEx Colon Sigmoid OIP5-AS1 0.21 0.27 lasso 3 0.25 3.3e-09 5.1 5.2 1.8e-07 0.75 0.07 0.92 FALSE
9 GTEx Heart Atrial Appendage NDUFAF1 0.36 0.28 enet 24 0.34 9.5e-16 5.0 -5.4 5.8e-08 -0.72 0.04 0.96 FALSE
10 GTEx Heart Atrial Appendage RTF1 0.14 0.07 lasso 4 0.08 2.4e-04 5.4 -5.3 1.2e-07 -0.99 0.02 0.95 FALSE
11 GTEx Heart Left Ventricle NDUFAF1 0.49 0.62 lasso 8 0.62 2.0e-41 5.2 -5.2 1.9e-07 -0.74 0.04 0.96 FALSE
12 GTEx Nerve Tibial NUSAP1 0.15 0.09 enet 10 0.15 9.8e-11 5.0 5.3 1.0e-07 0.84 0.08 0.92 FALSE
13 GTEx Nerve Tibial OIP5-AS1 0.20 0.22 enet 21 0.26 1.3e-18 5.2 5.3 1.4e-07 0.72 0.05 0.95 FALSE
14 GTEx Pancreas NDUFAF1 0.41 0.39 enet 20 0.42 2.7e-19 5.1 5.4 7.3e-08 0.74 0.04 0.95 FALSE
15 GTEx Prostate NDUFAF1 0.30 0.12 lasso 2 0.14 2.7e-04 5.1 5.3 1.1e-07 0.87 0.04 0.84 FALSE
16 GTEx Skin Sun Exposed Lower leg OIP5-AS1 0.13 0.17 lasso 3 0.23 5.0e-19 4.8 5.1 3.0e-07 0.79 0.16 0.83 FALSE
17 GTEx Thyroid OIP5 0.06 0.03 lasso 5 0.02 1.1e-02 5.0 5.4 7.9e-08 0.75 0.07 0.84 FALSE
18 GTEx Thyroid NDUFAF1 0.25 0.21 lasso 6 0.22 9.3e-17 5.0 5.2 2.5e-07 0.79 0.05 0.95 FALSE