Best TWAS P=5.76e-11 · Best GWAS P=1.48e-15 conditioned to 1.81e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | NEO1 | 0.07 | 0.09 | lasso | 2 | 0.09 | 3.9e-07 | -5.1 | -5.1 | 2.7e-07 | 0.45 | 0.93 | 0.02 | FALSE |
| 2 | GTEx | Pituitary | BBS4 | 0.27 | 0.02 | enet | 21 | 0.05 | 2.1e-02 | -5.7 | -6.5 | 5.8e-11 | 0.69 | 0.05 | 0.52 | TRUE |
| 3 | GTEx | Testis | ADPGK-AS1 | 0.17 | 0.05 | lasso | 4 | 0.03 | 1.3e-02 | -3.9 | 5.8 | 6.9e-09 | -0.72 | 0.02 | 0.91 | FALSE |
| 4 | NTR | Blood | NEO1 | 0.04 | 0.01 | lasso | 4 | 0.02 | 4.1e-06 | 4.8 | -5.2 | 2.3e-07 | 0.25 | 0.94 | 0.01 | FALSE |