Best TWAS P=1.21e-09 · Best GWAS P=3.53e-08 conditioned to 0.132
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ZNF232 | 0.13 | 0.06 | enet | 41 | 0.10 | 2.0e-08 | -1.7 | -5.2 | 1.8e-07 | -0.46 | 0.91 | 0.02 | FALSE |
| 2 | GTEx | Brain Putamen basal ganglia | AC012146.7 | 0.30 | 0.03 | enet | 23 | 0.03 | 7.6e-02 | 4.1 | -6.1 | 1.2e-09 | -0.74 | 0.08 | 0.20 | TRUE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | GP1BA | 0.35 | 0.16 | lasso | 11 | 0.18 | 5.9e-07 | 4.5 | 5.7 | 1.3e-08 | 0.77 | 0.07 | 0.88 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | AC012146.7 | 0.21 | 0.07 | enet | 17 | 0.18 | 1.3e-14 | 2.3 | -5.3 | 8.9e-08 | -0.60 | 0.89 | 0.05 | FALSE |
| 5 | NTR | Blood | MINK1 | 0.11 | 0.15 | lasso | 3 | 0.15 | 2.1e-46 | 5.5 | 5.4 | 7.2e-08 | 0.98 | 0.00 | 1.00 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | C17orf107 | 0.03 | 0.01 | enet | 8 | 0.03 | 5.1e-04 | 3.0 | 5.3 | 1.2e-07 | 0.70 | 0.01 | 0.71 | FALSE |
| 7 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | PFN1 | 0.16 | 0.00 | blup | 47 | 0.03 | 2.7e-02 | 4.6 | -5.2 | 2.4e-07 | -0.78 | 0.00 | 0.55 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GP1BA | 0.02 | 0.02 | blup | 49 | 0.02 | 9.3e-03 | 4.2 | 5.4 | 5.3e-08 | 0.86 | 0.01 | 0.74 | FALSE |
| 9 | The Cancer Genome Atlas | Stomach Adenocarcinoma | C17orf107 | 0.05 | 0.01 | blup | 40 | 0.03 | 2.0e-03 | 5.5 | 5.4 | 8.5e-08 | 0.75 | 0.00 | 0.95 | FALSE |