[Hub]/) : Traits : Arm fat percentage (left) :

chr17:6,644,945-8,161,149

Best TWAS P=1.77e-11 · Best GWAS P=8.87e-11 conditioned to 0.178

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum CHRNB1 0.29 0.14 lasso 5 0.14 1.0e-07 -5.7 -5.5 3.3e-08 0.82 0.09 0.90 FALSE
2 GTEx Breast Mammary Tissue (Male) CHRNB1 0.28 -0.01 lasso 6 0.02 9.6e-02 -5.7 -5.3 1.4e-07 0.75 0.02 0.68 FALSE
3 GTEx Esophagus Mucosa CHRNB1 0.19 0.11 lasso 2 0.13 7.3e-09 -5.7 -5.5 3.7e-08 0.82 0.28 0.72 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic CHRNB1 0.17 0.15 lasso 3 0.16 7.4e-09 -5.7 -5.7 1.2e-08 0.85 0.05 0.94 FALSE
5 NTR Blood TNFSF12 0.06 0.07 bslmm 462 0.07 9.4e-23 4.9 5.5 4.6e-08 -0.48 0.97 0.03 FALSE
6 ROSMAP Brain Pre-frontal Cortex FGF11 0.08 0.04 blup 454 0.04 1.2e-05 4.2 -5.4 8.0e-08 0.61 0.83 0.16 FALSE
7 ROSMAP Brain Pre-frontal Cortex CHRNB1 0.11 0.08 lasso 6 0.08 7.8e-11 -5.7 -5.6 2.1e-08 0.81 0.07 0.93 FALSE
8 YFS Blood CHRNB1 0.04 0.02 lasso 5 0.04 8.5e-12 -5.8 -5.5 2.8e-08 0.83 0.06 0.94 FALSE
9 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CHRNB1 0.07 0.04 blup 57 0.05 1.6e-03 -5.7 -6.2 4.1e-10 0.79 0.01 0.72 FALSE
10 The Cancer Genome Atlas Glioblastoma Multiforme AMAC1L3 0.14 0.12 lasso 3 0.12 1.8e-04 -6.4 6.2 4.4e-10 -0.95 0.00 0.92 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CHRNB1 0.06 0.07 lasso 6 0.07 1.8e-08 -4.9 -5.8 6.7e-09 0.73 0.16 0.84 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CHRNB1 0.04 0.03 blup 57 0.02 1.5e-03 5.0 -5.6 2.3e-08 0.62 0.06 0.35 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma C17orf81 0.04 0.05 enet 8 0.04 1.2e-05 -4.0 -5.3 1.1e-07 0.04 0.03 0.68 TRUE
14 The Cancer Genome Atlas Brain Lower Grade Glioma CHRNB1 0.05 0.04 blup 57 0.04 6.1e-05 -6.4 -5.5 3.7e-08 0.90 0.00 1.00 FALSE
15 The Cancer Genome Atlas Lung Adenocarcinoma CHRNB1 0.03 0.02 blup 57 0.02 7.8e-04 -5.8 -6.7 1.8e-11 0.82 0.01 0.98 TRUE
16 The Cancer Genome Atlas Prostate Adenocarcinoma TNFSF12-TNFSF13 0.03 0.00 lasso 4 0.01 2.9e-02 4.8 5.5 2.9e-08 -0.61 0.02 0.41 FALSE
17 The Cancer Genome Atlas Stomach Adenocarcinoma CHRNB1 0.06 0.00 blup 57 0.03 4.5e-03 -1.9 -6.4 1.7e-10 0.86 0.00 0.78 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma CHRNB1 0.09 0.02 blup 57 0.05 2.6e-05 4.2 -5.5 4.4e-08 0.71 0.12 0.74 FALSE