[Hub]/) : Traits : Arm fat percentage (left) : ← →

chr17:6,644,945-8,161,149

Best TWAS P=1.77e-11 · Best GWAS P=8.87e-11 conditioned to 0.178

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	CHRNB1	0.29	0.14	lasso	5	0.14	1.0e-07	-5.7	-5.5	3.3e-08	0.82	0.09	0.90	FALSE
2	GTEx	Breast Mammary Tissue (Male)	CHRNB1	0.28	-0.01	lasso	6	0.02	9.6e-02	-5.7	-5.3	1.4e-07	0.75	0.02	0.68	FALSE
3	GTEx	Esophagus Mucosa	CHRNB1	0.19	0.11	lasso	2	0.13	7.3e-09	-5.7	-5.5	3.7e-08	0.82	0.28	0.72	FALSE
4	GTEx	Skin Not Sun Exposed Suprapubic	CHRNB1	0.17	0.15	lasso	3	0.16	7.4e-09	-5.7	-5.7	1.2e-08	0.85	0.05	0.94	FALSE
5	NTR	Blood	TNFSF12	0.06	0.07	bslmm	462	0.07	9.4e-23	4.9	5.5	4.6e-08	-0.48	0.97	0.03	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	FGF11	0.08	0.04	blup	454	0.04	1.2e-05	4.2	-5.4	8.0e-08	0.61	0.83	0.16	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	CHRNB1	0.11	0.08	lasso	6	0.08	7.8e-11	-5.7	-5.6	2.1e-08	0.81	0.07	0.93	FALSE
8	YFS	Blood	CHRNB1	0.04	0.02	lasso	5	0.04	8.5e-12	-5.8	-5.5	2.8e-08	0.83	0.06	0.94	FALSE
9	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CHRNB1	0.07	0.04	blup	57	0.05	1.6e-03	-5.7	-6.2	4.1e-10	0.79	0.01	0.72	FALSE
10	The Cancer Genome Atlas	Glioblastoma Multiforme	AMAC1L3	0.14	0.12	lasso	3	0.12	1.8e-04	-6.4	6.2	4.4e-10	-0.95	0.00	0.92	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CHRNB1	0.06	0.07	lasso	6	0.07	1.8e-08	-4.9	-5.8	6.7e-09	0.73	0.16	0.84	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CHRNB1	0.04	0.03	blup	57	0.02	1.5e-03	5.0	-5.6	2.3e-08	0.62	0.06	0.35	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	C17orf81	0.04	0.05	enet	8	0.04	1.2e-05	-4.0	-5.3	1.1e-07	0.04	0.03	0.68	TRUE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	CHRNB1	0.05	0.04	blup	57	0.04	6.1e-05	-6.4	-5.5	3.7e-08	0.90	0.00	1.00	FALSE
15	The Cancer Genome Atlas	Lung Adenocarcinoma	CHRNB1	0.03	0.02	blup	57	0.02	7.8e-04	-5.8	-6.7	1.8e-11	0.82	0.01	0.98	TRUE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	TNFSF12-TNFSF13	0.03	0.00	lasso	4	0.01	2.9e-02	4.8	5.5	2.9e-08	-0.61	0.02	0.41	FALSE
17	The Cancer Genome Atlas	Stomach Adenocarcinoma	CHRNB1	0.06	0.00	blup	57	0.03	4.5e-03	-1.9	-6.4	1.7e-10	0.86	0.00	0.78	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	CHRNB1	0.09	0.02	blup	57	0.05	2.6e-05	4.2	-5.5	4.4e-08	0.71	0.12	0.74	FALSE