Best TWAS P=1.95e-08 · Best GWAS P=2.19e-09 conditioned to 0.742
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SLC9A3R2 | 0.15 | 0.09 | enet | 7 | 0.10 | 7.8e-12 | -4.7 | 5.3 | 1.1e-07 | -0.58 | 0.04 | 0.96 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SLC9A3R2 | 0.16 | 0.11 | lasso | 6 | 0.12 | 6.3e-15 | -5.7 | 5.2 | 1.5e-07 | -0.61 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CASKIN1 | 0.02 | 0.00 | blup | 38 | 0.01 | 4.5e-02 | 4.2 | -5.5 | 4.3e-08 | 0.45 | 0.03 | 0.04 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MLST8 | 0.09 | 0.07 | enet | 8 | 0.09 | 9.9e-09 | 4.7 | 5.1 | 2.7e-07 | -0.29 | 0.00 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | SLC9A3R2 | 0.06 | 0.03 | lasso | 5 | 0.03 | 3.7e-04 | -4.7 | 5.6 | 1.9e-08 | -0.59 | 0.17 | 0.31 | TRUE |