[Hub]/) : Traits : Arm fat mass (left) :

chr22:37,781,874-39,663,066

Best TWAS P=5.61e-10 · Best GWAS P=4.77e-09 conditioned to 0.0251

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta PLA2G6 0.10 0.02 enet 9 0.02 4.5e-02 4.2 6.2 5.6e-10 0.68 0.10 0.48 TRUE
2 GTEx Artery Aorta TMEM184B 0.17 0.07 enet 34 0.03 1.2e-02 5.1 -5.2 1.6e-07 -0.68 0.07 0.68 FALSE
3 GTEx Artery Aorta AL021977.1 0.13 0.00 enet 17 0.01 8.7e-02 5.2 -6.0 2.2e-09 -0.73 0.05 0.63 FALSE
4 GTEx Brain Cortex TMEM184B 0.29 0.12 lasso 7 0.09 1.6e-03 5.1 -5.5 4.8e-08 -0.91 0.02 0.83 FALSE
5 GTEx Cells EBV-transformed lymphocytes PLA2G6 0.28 0.17 enet 13 0.18 1.3e-06 -4.8 5.3 1.2e-07 0.69 0.25 0.61 FALSE
6 GTEx Cells Transformed fibroblasts PLA2G6 0.23 0.09 lasso 9 0.10 9.9e-08 5.0 5.4 5.5e-08 0.81 0.34 0.66 FALSE
7 GTEx Esophagus Gastroesophageal Junction PLA2G6 0.28 0.24 lasso 5 0.23 1.1e-08 -4.8 5.1 2.9e-07 0.64 0.49 0.43 FALSE
8 GTEx Esophagus Mucosa PLA2G6 0.22 0.02 lasso 6 0.04 1.9e-03 5.0 5.5 4.3e-08 0.77 0.13 0.85 FALSE
9 GTEx Esophagus Muscularis TMEM184B 0.11 0.01 enet 10 0.06 2.7e-04 2.9 -5.2 2.0e-07 -0.60 0.25 0.26 FALSE
10 GTEx Muscle Skeletal DMC1 0.13 0.01 enet 17 0.04 3.3e-05 4.6 5.2 1.9e-07 0.59 0.07 0.62 FALSE
11 GTEx Nerve Tibial PLA2G6 0.34 0.08 lasso 8 0.11 2.9e-08 -4.8 5.3 1.4e-07 0.72 0.38 0.61 FALSE
12 GTEx Nerve Tibial MAFF 0.14 0.06 lasso 3 0.05 1.2e-04 5.6 -5.6 2.2e-08 -0.98 0.02 0.97 FALSE
13 GTEx Skin Sun Exposed Lower leg BAIAP2L2 0.09 0.09 lasso 4 0.09 5.5e-08 4.8 -5.2 1.8e-07 -0.74 0.17 0.83 FALSE
14 GTEx Thyroid PLA2G6 0.34 0.20 lasso 5 0.18 4.5e-14 -4.8 5.1 2.8e-07 0.67 0.66 0.34 FALSE
15 GTEx Thyroid TMEM184B 0.19 0.16 lasso 7 0.18 1.0e-13 4.3 -5.4 5.4e-08 -0.67 0.75 0.24 FALSE
16 GTEx Thyroid AL021977.1 0.20 0.11 lasso 6 0.12 2.7e-09 4.2 -5.4 6.7e-08 -0.66 0.72 0.27 FALSE
17 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PLA2G6 0.05 0.01 blup 76 0.01 7.7e-02 5.9 5.5 3.6e-08 0.83 0.01 0.84 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma PLA2G6 0.03 0.02 lasso 2 0.03 6.5e-04 5.1 5.1 2.6e-07 0.81 0.06 0.46 FALSE