[Hub]/) : Traits : Arm fat mass (left) : ← →

chr22:37,781,874-39,663,066

Best TWAS P=5.61e-10 · Best GWAS P=4.77e-09 conditioned to 0.0251

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	PLA2G6	0.10	0.02	enet	9	0.02	4.5e-02	4.2	6.2	5.6e-10	0.68	0.10	0.48	TRUE
3	GTEx	Artery Aorta	AL021977.1	0.13	0.00	enet	17	0.01	8.7e-02	5.2	-6.0	2.2e-09	-0.73	0.05	0.63	FALSE
12	GTEx	Nerve Tibial	MAFF	0.14	0.06	lasso	3	0.05	1.2e-04	5.6	-5.6	2.2e-08	-0.98	0.02	0.97	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLA2G6	0.05	0.01	blup	76	0.01	7.7e-02	5.9	5.5	3.6e-08	0.83	0.01	0.84	FALSE
8	GTEx	Esophagus Mucosa	PLA2G6	0.22	0.02	lasso	6	0.04	1.9e-03	5.0	5.5	4.3e-08	0.77	0.13	0.85	FALSE
4	GTEx	Brain Cortex	TMEM184B	0.29	0.12	lasso	7	0.09	1.6e-03	5.1	-5.5	4.8e-08	-0.91	0.02	0.83	FALSE
15	GTEx	Thyroid	TMEM184B	0.19	0.16	lasso	7	0.18	1.0e-13	4.3	-5.4	5.4e-08	-0.67	0.75	0.24	FALSE
6	GTEx	Cells Transformed fibroblasts	PLA2G6	0.23	0.09	lasso	9	0.10	9.9e-08	5.0	5.4	5.5e-08	0.81	0.34	0.66	FALSE
16	GTEx	Thyroid	AL021977.1	0.20	0.11	lasso	6	0.12	2.7e-09	4.2	-5.4	6.7e-08	-0.66	0.72	0.27	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	PLA2G6	0.28	0.17	enet	13	0.18	1.3e-06	-4.8	5.3	1.2e-07	0.69	0.25	0.61	FALSE
11	GTEx	Nerve Tibial	PLA2G6	0.34	0.08	lasso	8	0.11	2.9e-08	-4.8	5.3	1.4e-07	0.72	0.38	0.61	FALSE
2	GTEx	Artery Aorta	TMEM184B	0.17	0.07	enet	34	0.03	1.2e-02	5.1	-5.2	1.6e-07	-0.68	0.07	0.68	FALSE
13	GTEx	Skin Sun Exposed Lower leg	BAIAP2L2	0.09	0.09	lasso	4	0.09	5.5e-08	4.8	-5.2	1.8e-07	-0.74	0.17	0.83	FALSE
10	GTEx	Muscle Skeletal	DMC1	0.13	0.01	enet	17	0.04	3.3e-05	4.6	5.2	1.9e-07	0.59	0.07	0.62	FALSE
9	GTEx	Esophagus Muscularis	TMEM184B	0.11	0.01	enet	10	0.06	2.7e-04	2.9	-5.2	2.0e-07	-0.60	0.25	0.26	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	PLA2G6	0.03	0.02	lasso	2	0.03	6.5e-04	5.1	5.1	2.6e-07	0.81	0.06	0.46	FALSE
14	GTEx	Thyroid	PLA2G6	0.34	0.20	lasso	5	0.18	4.5e-14	-4.8	5.1	2.8e-07	0.67	0.66	0.34	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	PLA2G6	0.28	0.24	lasso	5	0.23	1.1e-08	-4.8	5.1	2.9e-07	0.64	0.49	0.43	FALSE