[Hub]/) : Traits : Arm fat mass (left) :

chr8:21,249,296-24,094,711

Best TWAS P=1.31e-09 · Best GWAS P=4.49e-10 conditioned to 0.188

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HR 0.06 0.01 bslmm 452 0.03 3.8e-05 -2.5 5.2 2.0e-07 -0.01 0.04 0.88 FALSE
2 GTEx Cells Transformed fibroblasts SLC25A37 0.13 0.05 lasso 5 0.04 3.0e-04 -6.2 6.1 1.3e-09 -0.86 0.00 0.99 TRUE
3 GTEx Cells Transformed fibroblasts NUDT18 0.10 0.04 enet 6 0.03 4.7e-03 5.0 5.4 6.2e-08 -0.05 0.01 0.91 FALSE
4 GTEx Cells Transformed fibroblasts AC091171.1 0.15 0.06 lasso 2 0.05 2.2e-04 -5.4 5.3 1.4e-07 -0.05 0.01 0.97 FALSE
5 GTEx Esophagus Mucosa FAM160B2 0.15 0.05 enet 19 0.09 1.7e-06 5.2 5.3 1.1e-07 0.01 0.01 0.98 FALSE
6 GTEx Esophagus Mucosa AC091171.1 0.14 0.07 lasso 4 0.05 2.2e-04 5.4 5.5 3.9e-08 -0.06 0.01 0.99 TRUE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma NUDT18 0.09 0.03 blup 45 0.08 1.3e-04 -5.1 -5.2 1.8e-07 0.06 0.03 0.95 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma FAM160B2 0.06 0.07 lasso 1 0.06 2.3e-04 5.2 5.2 1.6e-07 -0.05 0.01 0.91 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SLC25A37 0.11 0.09 lasso 5 0.09 7.8e-10 -4.9 -5.5 4.5e-08 0.59 0.65 0.35 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LOXL2 0.16 0.03 lasso 4 0.05 1.2e-03 -4.9 5.9 4.3e-09 -0.59 0.01 0.78 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma NUDT18 0.11 0.22 lasso 6 0.22 3.6e-24 -5.4 -5.2 1.7e-07 0.06 0.02 0.98 FALSE
12 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma NUDT18 0.15 0.17 lasso 4 0.12 2.3e-04 -5.2 -5.4 6.1e-08 0.05 0.02 0.96 FALSE