[Hub]/) : Traits : Arm fat-free mass (left) : ← →

chr2:197,560,575-201,571,143

Best TWAS P=5.49e-14 · Best GWAS P=5.32e-16 conditioned to 0.000123

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	GTEx	Skin Sun Exposed Lower leg	MARS2	0.04	0.05	enet	8	0.03	1.2e-03	-7.63	7.5	5.5e-14	-0.86	0.11	0.88	TRUE
5	GTEx	Brain Hippocampus	FTCDNL1	0.35	0.24	enet	24	0.26	9.0e-07	-3.63	-5.8	7.5e-09	-0.10	0.30	0.21	TRUE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	C2orf60	0.03	0.03	blup	44	0.03	1.8e-04	-5.22	5.6	2.8e-08	-0.05	0.01	0.97	TRUE
10	GTEx	Lung	RFTN2	0.06	0.08	lasso	8	0.06	2.7e-05	-7.47	-7.4	1.5e-13	0.86	0.16	0.84	FALSE
17	GTEx	Whole Blood	PLCL1	0.08	0.08	enet	15	0.05	4.1e-05	-6.98	-7.4	1.9e-13	0.92	0.12	0.88	FALSE
12	GTEx	Spleen	RFTN2	0.11	0.03	enet	26	0.05	2.4e-02	-7.61	-7.2	5.9e-13	0.84	0.10	0.32	FALSE
13	GTEx	Spleen	MARS2	0.12	0.04	lasso	5	0.00	3.4e-01	-7.62	7.2	6.2e-13	-0.82	0.07	0.32	FALSE
15	GTEx	Thyroid	PLCL1	0.04	0.01	lasso	4	0.00	2.6e-01	-7.35	-6.9	7.4e-12	0.76	0.21	0.46	FALSE
3	GTEx	Adipose Subcutaneous	RFTN2	0.14	0.10	enet	11	0.13	5.3e-11	-6.83	-6.7	1.6e-11	0.86	0.38	0.62	FALSE
25	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RFTN2	0.05	0.01	blup	61	0.02	3.1e-02	-4.96	-6.5	5.9e-11	0.70	0.04	0.40	FALSE
16	GTEx	Thyroid	RFTN2	0.04	0.01	enet	11	0.01	9.5e-02	-7.59	-6.5	7.1e-11	0.80	0.09	0.72	FALSE
14	GTEx	Thyroid	SF3B1	0.04	0.02	enet	14	0.02	2.0e-02	-4.82	-6.4	1.9e-10	0.72	0.10	0.80	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLCL1	0.04	0.00	blup	130	0.02	4.0e-03	2.02	-6.2	5.5e-10	0.65	0.05	0.39	FALSE
21	YFS	Blood	PLCL1	0.10	0.10	lasso	9	0.14	1.5e-43	-6.98	-6.1	1.2e-09	0.83	0.80	0.20	FALSE
7	GTEx	Breast Mammary Tissue	SF3B1	0.06	0.06	lasso	4	0.03	6.6e-03	-4.99	-6.0	1.8e-09	0.61	0.17	0.68	FALSE
8	GTEx	Breast Mammary Tissue (Female)	SF3B1	0.05	-0.01	lasso	3	-0.01	8.1e-01	-4.95	-5.9	2.8e-09	0.65	0.05	0.11	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	C2orf47	0.25	0.01	lasso	3	0.00	2.8e-01	4.94	-5.5	4.2e-08	0.04	0.06	0.39	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	TYW5	0.11	0.12	lasso	5	0.11	5.5e-14	-5.22	5.5	4.2e-08	-0.04	0.02	0.98	FALSE
24	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C2orf60	0.04	0.05	lasso	5	0.03	2.1e-03	-5.48	5.5	4.3e-08	-0.04	0.01	0.93	FALSE
2	CommonMind	Brain Pre-frontal Cortex	TYW5	0.08	0.14	lasso	8	0.13	2.2e-15	-5.22	5.4	5.1e-08	-0.05	0.02	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PLCL1	0.06	0.01	blup	397	0.02	4.9e-04	-0.22	-5.4	5.3e-08	0.35	0.09	0.40	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	MARS2	0.05	0.03	enet	14	0.05	2.2e-07	4.17	5.3	1.0e-07	-0.75	0.20	0.79	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	C2orf69	0.07	0.04	enet	13	0.06	3.6e-08	-5.23	5.3	1.2e-07	-0.05	0.02	0.98	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	HSPD1	0.15	0.04	lasso	7	0.04	2.0e-02	-3.90	5.2	1.7e-07	-0.64	0.12	0.54	FALSE
4	GTEx	Brain Caudate basal ganglia	TYW5	0.23	0.11	lasso	3	0.11	5.4e-04	-4.34	5.1	2.9e-07	-0.03	0.04	0.57	FALSE