[Hub]/) : Traits : Arm fat-free mass (left) :

chr2:206,284,251-209,182,548

Best TWAS P=6.98e-11 · Best GWAS P=6.02e-10 conditioned to 0.000954

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous METTL21A 0.10 0.02 lasso 4 0.02 1.6e-02 -4.7 5.3 1.1e-07 0.32 0.23 0.07 FALSE
2 GTEx Cells Transformed fibroblasts CREB1 0.15 0.00 enet 7 0.00 2.8e-01 -4.7 -6.5 7.0e-11 -0.50 0.14 0.43 TRUE
3 GTEx Esophagus Gastroesophageal Junction NDUFS1 0.16 0.09 enet 22 0.03 2.4e-02 -4.5 5.2 2.5e-07 0.01 0.03 0.93 FALSE
4 GTEx Esophagus Mucosa METTL21A 0.10 0.10 enet 9 0.12 1.8e-08 -4.7 5.4 5.1e-08 0.57 0.76 0.23 FALSE
5 GTEx Nerve Tibial AC007383.4 0.14 0.06 lasso 6 0.05 3.0e-04 -4.8 5.3 9.4e-08 0.01 0.03 0.96 TRUE
6 GTEx Testis NDUFS1 0.15 0.08 lasso 6 0.08 2.1e-04 -4.6 5.2 2.5e-07 0.02 0.05 0.85 FALSE
7 The Cancer Genome Atlas Bladder Urothelial Carcinoma CREB1 0.03 0.01 blup 64 0.01 2.5e-02 -5.2 -5.2 1.6e-07 -0.49 0.13 0.36 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma FAM119A 0.04 0.02 blup 51 0.03 1.0e-06 -4.6 5.5 3.2e-08 0.64 0.03 0.95 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CREB1 0.11 0.02 enet 7 0.02 1.7e-03 4.9 -5.4 7.4e-08 -0.70 0.01 0.86 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma FAM119A 0.09 0.12 lasso 2 0.12 4.4e-12 -4.7 5.3 1.2e-07 0.50 0.03 0.96 FALSE