[Hub]/) : Traits : Arm fat-free mass (left) : ← →

chr2:217,456,567-220,226,393

Best TWAS P=2.02e-16 · Best GWAS P=7.57e-29 conditioned to 7.49e-12

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous BCS1L 0.06 0.01 enet 9 0.04 2.3e-04 -2.9 5.6 2.4e-08 -0.04 0.07 0.22 FALSE
2 GTEx Adipose Visceral Omentum PNKD 0.11 0.00 enet 31 0.00 2.3e-01 -5.8 6.1 1.2e-09 0.06 0.01 0.92 TRUE
3 GTEx Adrenal Gland PNKD 0.20 0.16 lasso 5 0.19 1.6e-07 -4.9 5.2 1.8e-07 0.07 0.03 0.96 FALSE
4 GTEx Brain Hypothalamus RP11-378A13.1 0.37 0.44 enet 17 0.45 5.6e-12 -4.7 5.3 1.1e-07 0.10 0.01 0.99 FALSE
5 GTEx Lung PNKD 0.13 0.04 enet 10 0.03 3.7e-03 -5.4 5.3 1.0e-07 0.08 0.02 0.98 FALSE
6 GTEx Pancreas PNKD 0.12 0.10 lasso 3 0.08 3.6e-04 -5.8 5.4 7.7e-08 0.05 0.00 0.97 FALSE
7 GTEx Pituitary PNKD 0.29 0.23 enet 21 0.24 8.9e-07 -5.8 5.6 1.9e-08 0.09 0.01 0.99 FALSE
8 GTEx Small Intestine Terminal Ileum RP11-378A13.1 0.39 0.17 enet 15 0.14 4.5e-04 -4.7 5.1 2.8e-07 0.06 0.03 0.92 FALSE
9 GTEx Thyroid PNKD 0.13 0.12 enet 13 0.14 6.3e-11 -5.8 5.2 2.4e-07 0.07 0.00 1.00 FALSE
10 METSIM Adipose PNKD 0.07 0.08 lasso 7 0.08 4.8e-12 -5.8 5.7 9.5e-09 0.07 0.00 1.00 FALSE
11 ROSMAP Brain Pre-frontal Cortex DIRC3 0.12 0.07 bslmm 697 0.08 2.7e-10 -6.5 6.9 4.0e-12 0.00 1.00 0.00 TRUE
12 YFS Blood PNKD 0.08 0.07 lasso 6 0.09 2.9e-27 -3.9 5.2 1.6e-07 0.05 0.04 0.95 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma TMBIM1 0.04 0.01 blup 49 0.02 4.8e-05 -4.7 5.2 1.7e-07 0.09 0.09 0.86 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DIRC3 0.12 0.01 blup 275 0.02 3.3e-03 -1.2 6.3 2.2e-10 -0.51 0.05 0.51 TRUE
15 The Cancer Genome Atlas Thyroid Carcinoma DIRC3 0.08 0.06 lasso 5 0.07 2.7e-07 -8.8 8.2 2.0e-16 -0.56 0.98 0.01 TRUE