[Hub]/) : Traits : Arm predicted mass (left) :

chr8:8,092,025-12,973,575

Best TWAS P=1.24e-10 · Best GWAS P=4.08e-11 conditioned to 0.0621

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM86B1 0.02 0.02 lasso 3 0.01 1.3e-02 4.5 5.6 2.3e-08 -0.63 0.01 0.96 FALSE
2 CommonMind Brain Pre-frontal Cortex FAM90A25P 0.11 0.08 lasso 3 0.08 1.4e-09 5.2 5.6 2.7e-08 -0.58 0.00 1.00 FALSE
3 CommonMind Brain Pre-frontal Cortex PINX1 0.07 0.07 enet 7 0.08 4.9e-10 -4.4 5.2 2.2e-07 -0.40 0.83 0.17 FALSE
4 GTEx Adipose Subcutaneous FDFT1 0.06 0.04 lasso 3 0.04 3.4e-04 -4.9 5.2 2.0e-07 -0.54 0.16 0.80 FALSE
5 GTEx Adipose Subcutaneous AF131215.2 0.24 0.15 lasso 7 0.14 3.5e-11 -5.5 5.8 5.7e-09 -0.82 0.44 0.56 FALSE
6 GTEx Adipose Subcutaneous AF131215.9 0.20 0.12 enet 60 0.17 1.1e-13 -5.5 5.8 8.6e-09 -0.67 0.15 0.85 FALSE
7 GTEx Adipose Visceral Omentum AF131215.2 0.12 0.08 lasso 6 0.06 4.6e-04 6.0 6.0 2.7e-09 -0.86 0.15 0.82 FALSE
8 GTEx Adipose Visceral Omentum AF131215.9 0.18 0.16 lasso 7 0.16 2.0e-08 6.0 6.1 1.3e-09 -0.87 0.07 0.93 FALSE
9 GTEx Adrenal Gland FAM86B3P 0.16 0.00 enet 18 0.03 2.2e-02 4.2 -5.1 2.7e-07 0.38 0.04 0.10 FALSE
10 GTEx Adrenal Gland AF131215.2 0.20 0.16 enet 12 0.13 2.2e-05 6.1 6.2 4.3e-10 -0.90 0.03 0.97 FALSE
11 GTEx Adrenal Gland AF131215.9 0.18 0.16 lasso 10 0.18 3.5e-07 6.1 6.1 1.1e-09 -0.87 0.04 0.95 FALSE
12 GTEx Artery Aorta ERI1 0.11 0.08 lasso 5 0.10 5.1e-06 6.1 -5.5 3.8e-08 0.60 0.00 1.00 FALSE
13 GTEx Artery Aorta AF131215.2 0.09 0.09 lasso 7 0.08 2.0e-05 -5.5 6.2 6.9e-10 -0.86 0.10 0.89 FALSE
14 GTEx Artery Aorta AF131215.9 0.13 0.05 lasso 6 0.07 1.3e-04 6.0 6.2 6.1e-10 -0.88 0.09 0.91 FALSE
15 GTEx Artery Tibial ERI1 0.05 0.02 lasso 7 0.01 3.2e-02 3.9 -5.1 3.0e-07 0.61 0.03 0.95 FALSE
16 GTEx Brain Cerebellar Hemisphere AF131215.2 0.15 0.17 lasso 3 0.09 3.0e-03 -5.9 6.0 1.8e-09 -0.86 0.06 0.78 FALSE
17 GTEx Breast Mammary Tissue AF131215.2 0.16 0.15 lasso 6 0.12 1.1e-06 -5.5 5.6 2.3e-08 -0.80 0.45 0.52 FALSE
18 GTEx Breast Mammary Tissue AF131215.9 0.10 0.10 lasso 8 0.12 8.7e-07 -5.0 5.7 1.0e-08 -0.79 0.27 0.72 FALSE
19 GTEx Breast Mammary Tissue (Female) AF131215.9 0.04 -0.01 enet 6 0.02 7.3e-02 -4.3 5.5 3.8e-08 -0.65 0.08 0.13 FALSE
20 GTEx Cells EBV-transformed lymphocytes AF131215.2 0.20 0.10 enet 14 0.11 1.5e-04 -5.9 5.9 4.2e-09 -0.85 0.15 0.82 FALSE
21 GTEx Cells EBV-transformed lymphocytes AF131215.9 0.20 0.15 enet 19 0.13 5.6e-05 -5.9 5.9 3.6e-09 -0.79 0.18 0.75 FALSE
22 GTEx Cells Transformed fibroblasts ERI1 0.34 0.35 lasso 7 0.35 1.9e-27 6.1 -6.2 5.9e-10 0.59 0.00 1.00 FALSE
23 GTEx Colon Sigmoid AF131215.2 0.10 0.00 enet 7 0.02 5.0e-02 5.4 5.2 1.7e-07 -0.76 0.12 0.53 FALSE
24 GTEx Colon Sigmoid AF131215.9 0.11 0.17 enet 5 0.09 4.9e-04 -5.9 5.8 6.7e-09 -0.87 0.10 0.76 FALSE
25 GTEx Colon Transverse AF131215.2 0.15 0.09 enet 32 0.07 3.1e-04 6.0 5.2 1.7e-07 -0.78 0.11 0.86 FALSE
26 GTEx Colon Transverse AF131215.9 0.12 0.14 enet 18 0.12 4.0e-06 -5.9 5.8 7.6e-09 -0.88 0.11 0.89 FALSE
27 GTEx Esophagus Mucosa AF131215.2 0.15 0.14 enet 15 0.18 4.3e-12 -5.1 5.6 2.2e-08 -0.84 0.69 0.31 FALSE
28 GTEx Esophagus Mucosa AF131215.9 0.18 0.16 lasso 14 0.19 1.6e-12 5.7 6.2 5.8e-10 -0.89 0.07 0.93 FALSE
29 GTEx Esophagus Muscularis ERI1 0.12 0.09 enet 13 0.08 7.7e-06 5.5 -5.3 1.2e-07 0.61 0.05 0.95 FALSE
30 GTEx Esophagus Muscularis AF131215.2 0.10 0.08 lasso 5 0.09 2.3e-06 -5.1 5.2 2.0e-07 -0.81 0.72 0.26 FALSE
31 GTEx Esophagus Muscularis FAM85A 0.10 0.01 enet 20 0.04 2.7e-03 -4.1 5.3 9.4e-08 -0.53 0.06 0.86 FALSE
32 GTEx Esophagus Muscularis AF131215.9 0.14 0.17 enet 16 0.17 1.6e-10 -5.9 6.3 2.7e-10 -0.86 0.15 0.85 FALSE
33 GTEx Heart Atrial Appendage AF131215.2 0.39 0.13 enet 26 0.21 6.6e-10 -5.1 5.4 7.4e-08 -0.75 0.63 0.37 FALSE
34 GTEx Heart Left Ventricle AF131215.2 0.05 0.01 enet 11 0.01 1.5e-01 5.9 6.1 1.3e-09 -0.86 0.08 0.82 FALSE
35 GTEx Heart Left Ventricle AF131215.9 0.07 0.10 enet 8 0.10 9.4e-06 -5.9 6.3 2.3e-10 -0.87 0.11 0.88 FALSE
36 GTEx Lung AF131215.2 0.12 0.08 lasso 5 0.08 1.0e-06 -5.9 6.1 8.9e-10 -0.86 0.18 0.82 FALSE
37 GTEx Lung AF131215.9 0.15 0.18 lasso 4 0.15 1.5e-11 -5.9 6.0 1.7e-09 -0.86 0.17 0.83 FALSE
38 GTEx Nerve Tibial AF131215.2 0.19 0.18 lasso 12 0.23 3.5e-16 -5.1 6.1 9.5e-10 -0.89 0.25 0.75 FALSE
39 GTEx Nerve Tibial AF131215.9 0.17 0.17 lasso 4 0.18 5.0e-13 -5.9 5.8 6.1e-09 -0.86 0.20 0.80 FALSE
40 GTEx Pancreas AF131215.2 0.16 0.16 enet 17 0.15 9.1e-07 -5.9 6.2 4.5e-10 -0.88 0.12 0.87 FALSE
41 GTEx Pancreas AF131215.9 0.25 0.24 enet 14 0.22 1.0e-09 6.0 6.4 1.2e-10 -0.90 0.07 0.93 TRUE
42 GTEx Prostate AF131215.2 0.18 0.02 lasso 6 0.02 9.6e-02 4.1 5.9 2.8e-09 -0.74 0.08 0.53 FALSE
43 GTEx Skin Not Sun Exposed Suprapubic AF131215.2 0.16 0.11 enet 21 0.20 3.9e-11 -5.1 5.6 2.2e-08 -0.87 0.11 0.89 FALSE
44 GTEx Skin Not Sun Exposed Suprapubic AF131215.9 0.17 0.14 lasso 8 0.19 9.4e-11 -5.9 5.8 6.7e-09 -0.86 0.13 0.87 FALSE
45 GTEx Skin Sun Exposed Lower leg AF131215.2 0.14 0.11 lasso 9 0.16 4.3e-13 -5.1 5.8 5.5e-09 -0.85 0.53 0.47 FALSE
46 GTEx Skin Sun Exposed Lower leg FAM85A 0.09 0.04 enet 28 0.04 1.4e-04 -4.1 5.3 1.5e-07 -0.45 0.09 0.81 FALSE
47 GTEx Skin Sun Exposed Lower leg AF131215.9 0.19 0.17 enet 29 0.21 3.9e-17 -5.9 6.3 3.7e-10 -0.86 0.20 0.80 FALSE
48 GTEx Spleen AF131215.2 0.16 0.08 enet 14 0.06 1.1e-02 -5.9 5.6 2.7e-08 -0.88 0.04 0.89 FALSE
49 GTEx Spleen AF131215.9 0.34 0.23 enet 16 0.15 1.2e-04 6.4 5.4 6.4e-08 -0.88 0.02 0.97 FALSE
50 GTEx Testis AF131215.2 0.28 0.18 enet 41 0.17 8.0e-08 -5.1 5.9 4.7e-09 -0.65 0.79 0.21 FALSE
51 GTEx Thyroid AF131215.2 0.11 0.15 enet 17 0.18 1.2e-13 -5.1 6.3 3.0e-10 -0.87 0.36 0.64 FALSE
52 GTEx Thyroid AF131215.9 0.11 0.08 enet 16 0.17 4.7e-13 -5.9 5.9 4.0e-09 -0.86 0.17 0.83 FALSE
53 GTEx Uterus AF131215.2 0.17 0.07 enet 13 0.09 7.1e-03 6.1 6.2 8.0e-10 -0.87 0.05 0.82 FALSE
54 GTEx Vagina AF131215.9 0.21 0.11 lasso 9 0.08 6.3e-03 6.4 6.4 2.1e-10 -0.92 0.04 0.92 FALSE
55 NTR Blood MSRA 0.02 0.01 blup 833 0.01 2.3e-05 4.2 -5.6 2.0e-08 0.61 0.35 0.64 FALSE
56 ROSMAP Brain Pre-frontal Cortex XKR6 0.11 0.10 enet 23 0.13 1.2e-16 -5.1 6.2 6.9e-10 -0.81 0.32 0.68 FALSE
57 ROSMAP Brain Pre-frontal Cortex FAM66A 0.23 0.26 enet 29 0.30 4.7e-39 5.5 5.8 4.9e-09 -0.60 0.00 1.00 FALSE
58 ROSMAP Brain Pre-frontal Cortex AF131215.3 0.08 0.10 lasso 7 0.12 8.3e-16 6.1 6.3 3.1e-10 -0.86 0.04 0.96 FALSE
59 ROSMAP Brain Pre-frontal Cortex RP11-481A20.11 0.06 0.04 blup 286 0.04 2.2e-06 5.2 5.1 2.8e-07 -0.61 0.01 0.98 FALSE
60 ROSMAP Brain Pre-frontal Cortex AF131215.2 0.49 0.57 lasso 7 0.57 9.0e-89 -5.9 6.0 1.8e-09 -0.87 0.16 0.84 FALSE
61 ROSMAP Brain Pre-frontal Cortex FAM85A 0.11 0.07 enet 23 0.11 4.3e-14 5.5 5.4 6.1e-08 -0.60 0.00 1.00 FALSE
62 The Cancer Genome Atlas Bladder Urothelial Carcinoma ERI1 0.05 0.01 blup 72 0.01 5.0e-02 6.1 -6.2 5.7e-10 0.50 0.00 0.88 FALSE
63 The Cancer Genome Atlas Lung Adenocarcinoma ERI1 0.06 0.04 blup 72 0.04 1.5e-05 5.0 -5.2 2.6e-07 0.53 0.03 0.96 FALSE
64 The Cancer Genome Atlas Testicular Germ Cell Tumors ZNF705D 0.23 0.20 lasso 3 0.24 4.7e-09 5.5 -5.3 1.0e-07 0.55 0.00 1.00 FALSE