Best TWAS P=3.37e-31 · Best GWAS P=1.1e-38 conditioned to 0.39
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | -9.9 | -7.9 | 2.1e-15 | -0.39 | 0.42 | 0.52 | FALSE |
| 2 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 4.6e-02 | 7.8 | 8.1 | 4.9e-16 | 0.21 | 0.05 | 0.28 | TRUE |
| 3 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | -11.0 | 10.9 | 1.9e-27 | 0.60 | 0.33 | 0.09 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | 11.4 | -11.6 | 3.4e-31 | -0.85 | 0.16 | 0.77 | TRUE |