[Hub]/) : Traits : Trunk fat percentage :

chr2:197,134,790-199,236,870

Best TWAS P=2.31e-12 · Best GWAS P=1.04e-11 conditioned to 0.00844

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SF3B1 0.06 0.07 enet 10 0.07 2.5e-09 5.6 5.7 1.5e-08 0.84 0.73 0.27 FALSE
2 GTEx Breast Mammary Tissue SF3B1 0.06 0.06 lasso 4 0.03 6.6e-03 5.7 5.2 2.1e-07 0.83 0.07 0.87 FALSE
3 GTEx Esophagus Mucosa SF3B1 0.04 0.02 lasso 4 0.01 5.7e-02 5.4 6.0 2.7e-09 0.90 0.03 0.91 FALSE
4 GTEx Lung SF3B1 0.06 0.04 enet 23 0.02 2.2e-02 5.4 7.0 2.3e-12 0.70 0.26 0.56 TRUE
5 GTEx Nerve Tibial SF3B1 0.06 0.09 lasso 8 0.08 3.3e-06 5.7 5.4 5.7e-08 0.82 0.78 0.21 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic SF3B1 0.08 0.00 enet 19 0.01 1.6e-01 5.6 5.4 8.2e-08 0.75 0.14 0.57 FALSE
7 GTEx Testis ANKRD44 0.33 0.35 enet 15 0.36 6.2e-17 6.8 6.5 8.7e-11 0.98 0.00 1.00 FALSE
8 GTEx Testis SF3B1 0.10 0.07 enet 17 0.08 2.6e-04 5.6 5.6 1.7e-08 0.89 0.21 0.77 FALSE
9 METSIM Adipose HSPD1 0.02 0.00 blup 323 0.01 1.8e-02 -2.7 5.6 2.7e-08 0.64 0.12 0.46 FALSE
10 ROSMAP Brain Pre-frontal Cortex SF3B1 0.02 0.01 blup 336 0.01 6.2e-03 5.2 6.2 4.4e-10 0.82 0.27 0.56 FALSE
11 ROSMAP Brain Pre-frontal Cortex RFTN2 0.03 0.04 blup 351 0.03 1.5e-04 4.0 -5.7 1.2e-08 -0.76 0.41 0.56 FALSE