[Hub]/) : Traits : Trunk fat percentage :

chr8:21,249,296-24,094,711

Best TWAS P=1.66e-09 · Best GWAS P=1.63e-09 conditioned to 0.233

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HR 0.06 0.01 bslmm 452 0.03 3.8e-05 -3.2 5.2 1.9e-07 0.51 0.05 0.84 FALSE
2 GTEx Adipose Subcutaneous NUDT18 0.10 0.07 enet 10 0.07 2.3e-06 5.9 5.5 4.6e-08 0.87 0.01 0.99 FALSE
3 GTEx Adrenal Gland NUDT18 0.35 0.20 lasso 6 0.19 1.6e-07 -5.0 -5.1 2.9e-07 -0.69 0.16 0.81 FALSE
4 GTEx Cells Transformed fibroblasts SLC25A37 0.13 0.05 lasso 5 0.04 3.0e-04 -6.0 5.6 1.8e-08 0.02 0.00 0.99 TRUE
5 GTEx Cells Transformed fibroblasts FAM160B2 0.18 0.09 lasso 5 0.10 4.0e-08 -5.7 5.4 7.6e-08 0.68 0.04 0.96 FALSE
6 GTEx Cells Transformed fibroblasts NUDT18 0.10 0.04 enet 6 0.03 4.7e-03 5.4 6.0 1.7e-09 0.89 0.01 0.94 TRUE
7 GTEx Cells Transformed fibroblasts AC091171.1 0.15 0.06 lasso 2 0.05 2.2e-04 -5.7 5.6 1.8e-08 0.69 0.05 0.92 FALSE
8 GTEx Esophagus Mucosa FAM160B2 0.15 0.05 enet 19 0.09 1.7e-06 5.8 5.5 3.5e-08 0.77 0.01 0.99 FALSE
9 GTEx Esophagus Mucosa NUDT18 0.21 0.23 enet 8 0.23 3.9e-15 -5.0 -5.3 1.5e-07 -0.73 0.32 0.67 FALSE
10 GTEx Esophagus Mucosa AC091171.1 0.14 0.07 lasso 4 0.05 2.2e-04 5.9 6.0 1.7e-09 0.94 0.01 0.99 FALSE
11 GTEx Skin Not Sun Exposed Suprapubic NUDT18 0.31 0.15 enet 13 0.22 4.6e-12 -5.0 -5.3 1.5e-07 -0.71 0.31 0.68 FALSE
12 GTEx Thyroid NUDT18 0.17 0.19 lasso 3 0.19 3.2e-14 -5.2 -5.2 2.0e-07 -0.72 0.28 0.72 FALSE
13 METSIM Adipose FAM160B2 0.06 0.03 enet 10 0.04 1.2e-06 5.8 5.1 3.0e-07 0.82 0.01 0.99 FALSE
14 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma NUDT18 0.09 0.03 blup 45 0.08 1.3e-04 -5.4 -5.7 1.5e-08 -0.78 0.05 0.92 FALSE
15 The Cancer Genome Atlas Colon Adenocarcinoma FAM160B2 0.06 0.07 lasso 1 0.06 2.3e-04 5.8 5.8 7.7e-09 0.93 0.01 0.93 FALSE
16 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LOXL2 0.16 0.03 lasso 4 0.05 1.2e-03 -4.4 5.4 6.0e-08 0.10 0.01 0.44 FALSE
17 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma NUDT18 0.10 0.16 lasso 2 0.16 2.3e-09 -5.4 -5.3 1.0e-07 -0.71 0.09 0.91 FALSE
18 The Cancer Genome Atlas Brain Lower Grade Glioma NUDT18 0.11 0.22 lasso 6 0.22 3.6e-24 -5.7 -5.7 1.4e-08 -0.78 0.06 0.94 FALSE
19 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NUDT18 0.06 0.08 lasso 3 0.07 1.6e-08 -5.4 -5.3 1.4e-07 -0.71 0.12 0.88 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma FAM160B2 0.05 0.01 enet 11 0.03 1.7e-04 -5.5 5.3 1.1e-07 0.70 0.03 0.94 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma NUDT18 0.17 0.25 blup 45 0.27 6.2e-28 -5.0 -5.2 1.9e-07 -0.69 0.16 0.84 FALSE
22 The Cancer Genome Atlas Thyroid Carcinoma FAM160B2 0.08 0.06 lasso 4 0.05 1.4e-05 -5.7 5.5 4.8e-08 0.64 0.04 0.95 FALSE
23 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma NUDT18 0.15 0.17 lasso 4 0.12 2.3e-04 -5.5 -5.8 5.8e-09 -0.78 0.02 0.95 FALSE