Best TWAS P=3.78e-09 · Best GWAS P=1.5e-10 conditioned to 0.0386
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | STK33 | 0.18 | 0.18 | lasso | 9 | 0.20 | 3.8e-24 | -4.3 | 5.3 | 1.5e-07 | 0.08 | 0.89 | 0.11 | TRUE |
2 | GTEx | Prostate | SBF2 | 0.21 | 0.05 | lasso | 7 | 0.03 | 6.7e-02 | -5.4 | -5.6 | 2.0e-08 | -0.83 | 0.05 | 0.70 | FALSE |
3 | GTEx | Testis | SBF2 | 0.10 | 0.01 | lasso | 5 | 0.02 | 5.0e-02 | -5.2 | 5.2 | 1.7e-07 | 0.83 | 0.07 | 0.81 | FALSE |
4 | NTR | Blood | ADM | 0.04 | 0.04 | enet | 13 | 0.04 | 1.6e-13 | -5.3 | 5.6 | 1.7e-08 | 0.85 | 0.22 | 0.78 | FALSE |
5 | YFS | Blood | ADM | 0.08 | 0.11 | enet | 25 | 0.12 | 9.4e-36 | -5.3 | 5.9 | 3.8e-09 | 0.82 | 0.61 | 0.39 | TRUE |