Best TWAS P=3.32e-11 · Best GWAS P=7.05e-21 conditioned to 7.35e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | CERS5 | 0.08 | 0.00 | enet | 23 | 0.01 | 6.4e-02 | -2.9 | 5.3 | 1.1e-07 | 0.22 | 0.28 | 0.21 | TRUE |
| 2 | GTEx | Lung | CERS5 | 0.07 | 0.06 | enet | 12 | 0.07 | 2.8e-06 | -3.4 | 5.3 | 9.2e-08 | 0.28 | 0.94 | 0.04 | FALSE |
| 3 | GTEx | Lung | LARP4 | 0.07 | 0.05 | enet | 15 | 0.05 | 1.8e-04 | -3.5 | -5.3 | 8.8e-08 | 0.00 | 0.43 | 0.37 | TRUE |
| 4 | GTEx | Testis | FAIM2 | 0.27 | 0.09 | lasso | 5 | 0.06 | 9.3e-04 | 7.2 | -6.6 | 3.3e-11 | -0.68 | 0.04 | 0.88 | TRUE |
| 5 | YFS | Blood | ATF1 | 0.05 | 0.07 | lasso | 9 | 0.07 | 2.0e-21 | 5.0 | 5.3 | 1.4e-07 | 0.06 | 0.01 | 0.99 | FALSE |