TWAS hub - ATF1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0290	0.0140	4.8e-03	0.017	0.027	0.012	0.025	0.018	3.5e-03	2.6e-04	1.1e-02	4.6e-04	2.5e-03
2	GTEx	Adipose Subcutaneous	0.0730	0.0290	2.9e-04	0.055	NA	0.040	NA	0.039	2.9e-05	NA	3.1e-04	NA	3.7e-04
3	GTEx	Artery Aorta	0.2610	0.0690	2.7e-09	0.293	NA	0.261	NA	0.276	1.5e-16	NA	1.3e-14	NA	1.5e-15
4	GTEx	Artery Coronary	0.1980	0.0810	2.9e-03	0.092	NA	0.035	NA	0.045	5.3e-04	NA	2.5e-02	NA	1.2e-02
5	GTEx	Artery Tibial	0.2426	0.0586	1.6e-13	0.260	NA	0.223	NA	0.246	2.2e-20	NA	2.2e-17	NA	2.7e-19
6	GTEx	Breast Mammary Tissue	0.0690	0.0340	8.5e-03	0.073	NA	0.028	NA	0.043	1.3e-04	NA	1.3e-02	NA	2.9e-03
7	GTEx	Breast Mammary Tissue (Male)	0.0453	0.0674	2.8e-01	-0.013	NA	-0.004	NA	0.009	9.0e-01	NA	4.1e-01	NA	1.9e-01
8	GTEx	Breast Mammary Tissue (Female)	0.0430	0.0443	2.0e-01	0.035	NA	0.002	NA	-0.003	3.3e-02	NA	2.7e-01	NA	4.0e-01
9	GTEx	Esophagus Gastroesophageal Junction	0.1450	0.0540	1.3e-04	0.150	NA	0.105	NA	0.143	4.4e-06	NA	1.2e-04	NA	7.8e-06
10	GTEx	Esophagus Muscularis	0.1490	0.0500	1.0e-05	0.168	NA	0.142	NA	0.158	2.1e-10	NA	5.6e-09	NA	7.5e-10
11	GTEx	Muscle Skeletal	0.0933	0.0381	6.2e-05	0.056	NA	0.024	NA	0.066	3.2e-06	NA	1.9e-03	NA	5.0e-07
12	GTEx	Skin Sun Exposed Lower leg	0.0680	0.0260	6.8e-05	0.068	NA	0.053	NA	0.077	2.5e-06	NA	3.2e-05	NA	6.1e-07
13	GTEx	Whole Blood	0.0670	0.0270	1.7e-04	0.089	NA	0.060	NA	0.072	1.3e-08	NA	3.1e-06	NA	3.5e-07
14	NTR	Blood	0.0563	0.0144	0.0e+00	0.068	0.066	0.068	0.064	0.068	4.4e-21	2.0e-20	4.0e-21	6.7e-20	7.4e-21
15	YFS	Blood	0.0523	0.0138	0.0e+00	0.071	0.059	0.067	0.066	0.068	4.0e-22	1.3e-18	4.1e-21	1.4e-20	2.0e-21
16	TCGA	Colon Adenocarcinoma	0.0990	0.0480	9.6e-05	0.045	0.053	0.056	NA	0.055	1.3e-03	4.9e-04	3.5e-04	NA	4.1e-04
17	TCGA	Brain Lower Grade Glioma	0.0348	0.0181	6.2e-04	0.040	0.024	0.031	NA	0.035	2.0e-05	8.0e-04	1.7e-04	NA	6.2e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Hair/balding pattern: Pattern 4	11.9	28.9	43.3	0.8	6.6	6.0	6.2	6.0	4.9	-0.7	6.1	5.8	6.0	6.2	5.3	-4.2	-4.6	-6.1	5.9	5.4
Blood White Count	10.7	79.6	116.6	0.6	10.4	10.2	10.2	10.1	8.9	-1.0	10.5	10.0	10.2	10.5	10.8	-6.0	-7.6	-8.7	9.5	7.3
Blood Platelet Count	9.1	105.9	171.6	7.4	11.6	10.9	10.9	10.8	7.9	-1.6	10.0	10.2	10.9	11.7	9.1	-10.3	-10.8	-13.1	10.3	12.2
Impedance of leg (left)	8.5	41.1	80.1	-1.6	-7.0	-6.1	-6.2	-6.0	-6.2	-0.1	-6.7	-6.7	-6.2	-6.9	-6.7	5.8	8.0	9.0	-5.3	-8.3
Diastolic blood pressure, automated reading	7.9	24.4	41.0	-1.2	-5.3	-6.1	-5.7	-6.0	-3.9	-2.6	-3.5	-5.8	-6.1	-6.4	-3.4	3.8	4.5	5.8	-5.0	-5.2
Impedance of leg (right)	7.8	37.8	78.7	-1.9	-6.6	-5.8	-5.9	-5.7	-5.9	-0.3	-6.3	-6.4	-5.9	-6.6	-6.3	5.6	8.0	8.9	-4.8	-8.2
Impedance of whole body	7.3	37.1	71.1	-0.6	-6.6	-5.9	-6.0	-5.8	-6.4	-1.3	-6.2	-6.5	-6.0	-6.6	-6.4	5.0	7.2	8.4	-5.1	-7.8
Hair/balding pattern: Pattern 3	6.1	9.1	19.6	3.0	3.2	2.8	2.8	2.9	2.2	-0.5	3.4	2.2	2.8	3.1	2.4	-4.4	-2.9	-3.8	3.1	3.8
Alcohol usually taken with meals	5.9	9.5	16.8	1.0	3.5	2.9	3.0	2.8	2.7	-0.2	3.4	3.1	2.9	3.2	3.1	-4.1	-3.9	-3.9	2.7	3.4
Systolic Blood Pressure	5.4	26.9	57.8	-3.5	-5.0	-5.7	-5.2	-5.5	-2.8	-1.9	-3.1	-5.7	-5.7	-6.2	-2.4	5.3	6.7	7.6	-4.2	-7.1
Lung FVC	5.2	26.4	44.5	-0.4	6.0	5.3	5.7	5.4	5.9	0.2	6.7	5.5	5.4	5.6	5.9	-3.6	-3.8	-5.6	5.8	5.0
Ever had prostate specific antigen (PSA) test	5.0	5.8	11.8	-0.2	2.8	2.6	2.7	2.7	3.1	-0.8	2.7	2.4	2.5	2.7	3.4	-1.8	-1.3	-1.9	3.0	1.4
Impedance of arm (right)	4.9	22.8	47.5	0.0	-5.0	-4.5	-4.7	-4.4	-5.4	-2.5	-4.5	-5.1	-4.6	-5.2	-5.0	3.4	5.6	6.9	-3.7	-6.4
Schizophrenia vs Biploar Disorder	4.8	6.4	10.5	-0.7	-3.2	-3.0	-3.0	-2.9	-2.0	1.8	-2.0	-2.7	-2.9	-3.0	-2.3	3.2	2.0	2.3	-2.5	-1.9
Heel T-Score	4.7	37.4	56.1	2.3	-7.3	-7.1	-7.2	-7.1	-7.5	-1.9	-6.5	-7.0	-7.1	-6.8	-7.2	4.4	3.5	4.8	-7.4	-3.6
Trunk fat percentage	4.6	18.3	27.7	-1.0	-4.9	-4.5	-4.7	-4.5	-4.0	-2.1	-5.1	-4.4	-4.5	-4.7	-3.6	3.9	3.5	5.3	-4.5	-5.0
Heel bone mineral density (BMD) T-score, automated (right)	4.6	10.6	19.3	2.8	-3.9	-3.8	-4.0	-3.9	-4.4	-2.1	-3.2	-3.6	-3.8	-3.6	-4.0	1.5	0.5	1.5	-3.9	-0.8
Financial difficulties in last 2 years	4.5	6.1	11.2	1.7	-2.9	-3.3	-3.2	-3.3	-2.6	-1.7	-1.9	-3.2	-3.3	-3.1	-2.2	1.1	0.6	1.0	-2.7	-0.5
Medication: Amlodipine	4.5	6.3	13.0	-1.1	-2.6	-2.6	-2.5	-2.4	-1.2	-1.8	-2.2	-3.0	-2.7	-2.7	-1.0	2.8	3.4	3.6	-1.7	-3.6
Hypertension (Self-reported)	4.5	12.6	21.7	-1.6	-3.6	-4.2	-3.8	-4.0	-2.0	-3.0	-2.3	-4.3	-4.2	-4.4	-1.4	3.6	4.1	4.7	-2.4	-4.3
Average weekly beer plus cider intake	4.4	6.3	14.5	-1.1	-2.9	-2.5	-2.5	-2.5	-2.1	0.4	-3.8	-2.3	-2.5	-2.7	-2.7	2.2	2.6	3.0	-2.3	-2.5
Schizophrenia (2014)	4.3	9.4	18.2	-0.3	-3.5	-3.1	-3.3	-3.0	-2.6	-0.2	-2.7	-3.6	-3.2	-3.6	-2.8	3.1	3.5	4.3	-2.1	-4.0
Heel bone mineral density (BMD) T-score, automated (left)	4.3	9.7	15.5	1.2	-3.8	-3.6	-3.8	-3.7	-3.9	-1.7	-3.1	-3.5	-3.6	-3.5	-3.7	2.1	1.7	2.5	-3.5	-1.9
Systolic blood pressure, automated reading	4.2	12.1	24.3	-1.4	-3.4	-4.0	-3.8	-3.9	-2.5	-1.6	-2.1	-4.0	-4.0	-4.3	-1.9	2.3	3.9	4.9	-3.6	-4.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.2	8.9	12.6	-0.5	3.4	3.4	3.3	3.3	2.9	-0.1	3.5	3.5	3.4	3.4	3.2	-2.7	-2.7	-3.0	2.9	2.6
High blood pressure	4.1	11.5	20.2	-2.0	-3.3	-4.0	-3.5	-3.8	-1.8	-2.8	-2.2	-4.0	-4.0	-4.2	-1.3	3.4	4.2	4.5	-2.2	-4.2
Reason for reducing amount of alcohol drunk: Health precaution	4.1	4.8	8.1	-0.3	-2.4	-2.5	-2.3	-2.4	-2.0	-0.8	-1.5	-2.8	-2.5	-2.5	-2.3	1.7	2.3	2.7	-2.0	-2.4
Impedance of arm (left)	4.0	18.7	39.4	0.0	-4.6	-4.1	-4.2	-4.0	-4.7	-2.1	-4.1	-4.7	-4.2	-4.7	-4.3	3.3	5.2	6.3	-3.4	-5.9
Crohns Disease (2012)	3.7	5.9	10.4	-0.7	2.6	2.4	2.5	2.5	3.2	0.7	2.9	2.6	2.5	2.7	3.2	-1.5	-2.3	-2.6	2.5	2.1
Schizophrenia (2018)	3.6	7.4	15.8	-0.9	-2.9	-2.4	-2.5	-2.4	-2.3	0.1	-2.4	-3.0	-2.6	-2.8	-2.4	3.3	3.7	4.0	-1.5	-3.9
Medication: Blood pressure	3.6	6.9	12.2	-0.8	-2.6	-3.3	-2.9	-3.1	-1.4	-1.9	-1.7	-3.5	-3.3	-3.3	-1.1	2.0	3.0	3.3	-1.9	-3.1
Illnesses of father: High blood pressure	3.6	4.5	14.2	0.1	-2.0	-2.0	-1.9	-2.0	-2.6	-3.8	-2.5	-1.9	-2.0	-2.1	-1.6	1.8	1.9	2.2	-1.9	-1.9
Bipolar Disorder or Schizophrenia	3.5	8.5	21.4	-1.3	-2.9	-2.5	-2.6	-2.4	-2.4	-0.0	-2.9	-3.3	-2.6	-2.9	-2.7	2.9	4.0	4.6	-1.6	-4.5
Sitting height	3.5	25.1	41.5	-2.2	-5.5	-5.4	-5.3	-5.5	-3.9	-0.5	-4.4	-5.3	-5.4	-5.9	-4.9	4.7	5.3	6.4	-5.1	-6.0
Body fat percentage	3.4	13.4	20.3	-1.0	-4.3	-3.9	-4.1	-3.9	-3.5	-2.0	-4.5	-3.7	-3.9	-4.1	-3.0	3.4	2.6	4.3	-4.1	-4.0
Mother’s age at death	3.3	4.2	5.9	-1.1	-2.4	-2.2	-2.2	-2.2	-1.4	1.4	-2.4	-2.0	-2.2	-2.2	-2.4	1.8	1.9	2.1	-2.4	-1.8
Qualifications: nursing, teaching	3.2	5.0	9.1	0.2	2.7	2.3	2.4	2.4	2.4	-0.1	3.0	1.9	2.2	2.4	2.4	-2.4	-1.8	-2.2	2.6	2.2
Relative age voice broke	3.1	4.7	9.3	-1.7	2.8	2.8	2.9	2.8	2.2	0.8	1.6	3.1	2.9	2.6	2.2	-1.4	-0.6	-0.8	2.4	0.3
Trunk fat mass	3.1	13.5	20.5	-1.4	-4.3	-3.8	-4.0	-3.9	-3.2	-1.7	-4.3	-3.6	-3.8	-4.0	-3.0	3.8	2.9	4.5	-4.1	-4.4
Mouth/teeth dental problems: Mouth ulcers	3.1	4.9	12.5	1.3	2.4	2.0	2.2	2.1	1.8	-0.1	2.0	2.1	2.0	2.3	1.3	-2.2	-2.2	-3.5	2.1	3.5
Vascular/heart problems diagnosed by doctor	3.1	8.4	13.6	1.4	2.9	3.5	3.0	3.3	1.5	2.7	1.9	3.5	3.5	3.6	1.0	-3.0	-3.7	-3.6	1.7	3.3
Height	3.0	58.1	111.2	-3.3	-8.5	-7.5	-7.3	-7.5	-5.6	-0.1	-6.8	-7.7	-7.5	-8.3	-6.8	8.8	9.5	10.5	-6.6	-10.3
Medication: Blood pressure	3.0	5.4	13.6	-1.7	-2.0	-2.0	-1.8	-2.0	-1.0	-1.3	-1.9	-2.1	-2.0	-2.2	-0.8	3.7	3.4	3.5	-1.3	-3.6
Forced expiratory volume in 1-second (FEV1), predicted	3.0	6.2	14.6	-1.7	-2.5	-1.9	-1.8	-1.9	-2.3	-0.8	-2.7	-1.9	-1.9	-2.3	-2.3	3.5	3.6	3.8	-1.4	-3.8
Comparative body size at age 10	2.9	8.0	19.9	2.1	2.7	2.6	2.4	2.5	1.4	-0.8	2.4	3.0	2.6	2.9	1.9	-2.8	-4.4	-4.5	2.0	4.4
Medication for cholesterol	2.9	4.3	8.1	0.1	2.4	2.8	2.7	2.7	1.4	1.3	2.0	2.7	2.8	2.8	1.2	-1.2	-1.6	-1.9	1.7	1.5
Current tobacco smoking	2.8	4.7	8.2	0.8	2.4	1.8	2.1	1.9	2.6	0.2	2.8	1.7	1.8	2.2	2.7	-1.5	-2.3	-2.9	2.5	2.7
Smoking status: Current	2.8	4.5	8.5	1.0	2.3	1.8	2.0	1.8	2.4	0.5	2.7	1.7	1.8	2.1	2.3	-1.7	-2.3	-2.9	2.4	2.8
Bilateral oophorectomy (both ovaries removed)	2.7	3.1	5.0	-0.7	-2.1	-1.8	-1.8	-1.8	-1.6	-0.1	-2.2	-1.8	-1.8	-1.9	-2.1	1.9	1.8	1.9	-1.7	-1.7
Medication: Atenolol	2.7	3.3	5.6	0.6	-2.1	-2.3	-2.2	-2.3	-1.5	0.6	-2.1	-2.4	-2.3	-2.1	-1.7	2.0	1.2	1.2	-1.8	-1.0
Standing height	2.7	27.0	58.1	-2.6	-5.6	-4.6	-4.6	-4.7	-4.0	-0.1	-4.8	-4.7	-4.6	-5.3	-4.7	6.3	6.8	7.6	-4.5	-7.6
Friendships satisfaction	2.6	3.2	10.9	2.3	1.5	1.0	0.9	1.1	0.8	-0.0	1.6	1.0	1.0	1.2	0.9	-2.8	-2.9	-2.8	0.7	3.3
Alcohol drinker status: Previous	2.6	3.0	7.6	0.9	-2.0	-1.5	-1.6	-1.4	-2.3	-1.8	-1.4	-1.8	-1.5	-1.5	-2.0	2.8	1.9	1.6	-1.3	-1.4
Tinnitus: Yes, but not now, but have in the past	2.5	2.6	5.4	0.0	1.8	1.5	1.4	1.4	1.4	0.2	2.0	1.5	1.5	1.5	1.7	-2.3	-2.2	-1.9	1.5	1.9
High blood pressure (siblings)	2.5	3.6	5.6	-0.3	-2.1	-2.2	-2.1	-2.2	-1.3	-1.8	-1.4	-2.4	-2.3	-2.3	-1.3	1.6	2.1	2.4	-1.2	-1.9
Pulse wave Arterial Stiffness index	2.4	2.8	5.4	0.9	-2.2	-2.1	-2.3	-2.1	-1.6	0.4	-1.1	-2.3	-2.2	-2.2	-1.6	0.5	0.7	1.2	-1.8	-0.9
Birth weight of first child	2.4	4.4	13.4	2.8	1.8	1.4	1.3	1.3	0.5	-1.1	1.9	1.7	1.5	1.7	0.9	-2.4	-3.7	-3.4	0.9	3.5
Leg pain on walking	2.4	3.1	7.0	0.5	1.7	1.8	1.7	1.9	1.2	-0.3	1.4	1.8	1.8	2.0	1.5	-1.8	-1.6	-2.6	1.9	2.6
Smoking status: Previous	2.4	3.6	7.1	-0.1	-2.0	-1.9	-1.8	-1.8	-1.4	0.2	-1.8	-2.5	-2.0	-2.0	-2.0	1.9	2.7	2.4	-1.0	-2.4
Leg fat percentage (left)	2.4	8.6	13.8	-0.7	-3.5	-3.2	-3.4	-3.3	-2.8	-1.6	-3.7	-2.9	-3.2	-3.2	-2.4	2.9	1.6	3.1	-3.5	-2.8
Medication: Co-codamol	2.3	2.7	5.4	-2.0	1.5	2.0	1.9	1.9	2.3	0.3	0.9	2.2	2.0	1.8	2.3	-0.1	-0.4	-0.3	1.8	-0.3
Hearing aid user	2.3	2.6	6.7	2.2	-1.2	-1.8	-1.7	-1.7	-2.3	-1.2	-1.6	-1.9	-1.8	-1.7	-2.6	-1.3	0.1	0.2	-1.3	0.4
Cardiovascular Disease	2.2	7.2	13.2	-0.6	-2.6	-3.2	-2.8	-3.1	-2.4	-2.7	-2.3	-3.1	-3.2	-3.6	-1.9	1.9	3.0	3.3	-1.7	-2.6
Type 2 Diabetes (T2D) (2018)	2.2	4.2	9.9	-3.1	1.8	2.2	2.1	2.1	3.0	1.7	2.1	2.5	2.2	1.9	3.0	0.2	0.0	0.1	2.0	-0.8
Qualifications: None of the above	2.2	4.6	9.2	1.9	-2.3	-2.4	-2.4	-2.3	-2.3	1.0	-2.7	-3.0	-2.5	-2.3	-3.0	0.6	2.0	1.4	-1.6	-1.1
Illnesses of siblings	2.2	3.0	5.1	0.3	1.9	1.9	1.9	1.8	1.4	1.2	1.6	2.1	1.9	2.1	1.5	-1.2	-2.1	-2.3	1.5	1.9
Qualifications: College or University degree	2.2	7.0	13.5	-1.0	3.3	3.2	3.2	3.2	2.4	0.3	3.7	3.2	3.2	2.8	2.3	-1.8	-1.6	-2.1	3.0	2.1
HbA1C	2.1	2.3	6.0	0.0	1.6	1.6	1.6	1.5	1.8	-0.2	1.9	1.8	1.7	1.6	2.4	-1.4	-1.4	-1.4	1.0	1.1
Ever had hysterectomy (womb removed)	2.1	2.3	5.1	-0.4	-1.6	-1.5	-1.6	-1.6	-1.6	-0.2	-2.2	-1.1	-1.4	-1.7	-2.0	1.0	1.1	1.7	-2.1	-1.6
Diabetes (self-reported)	2.1	3.2	8.9	-3.0	1.6	1.9	1.8	1.9	2.5	0.6	1.4	1.8	1.9	1.6	2.5	0.3	0.8	0.9	1.9	-1.6
Whole body fat mass	2.1	8.6	13.1	-1.2	-3.4	-3.1	-3.2	-3.1	-2.5	-1.7	-3.6	-2.7	-3.0	-3.2	-2.2	3.1	1.9	3.4	-3.5	-3.3
Medication: Lansoprazole	2.0	2.3	4.3	-0.8	1.6	2.0	1.8	2.0	1.0	-1.7	0.8	2.0	2.0	1.9	1.8	-0.6	-0.6	-0.3	2.1	0.0
Illnesses of mother	2.0	2.4	5.1	-0.8	1.7	2.2	2.0	2.1	0.7	0.3	1.3	2.3	2.2	2.0	0.7	-0.5	-0.7	-1.3	1.8	1.2
Pulse wave reflection index	2.0	2.4	8.9	3.0	-1.4	-1.8	-1.9	-1.7	-1.6	-0.7	0.1	-1.9	-1.8	-1.6	-1.3	-0.6	-1.0	-0.9	-1.4	1.6
Loud music exposure frequency	2.0	2.2	4.2	0.9	1.5	1.6	1.5	1.7	0.6	-2.1	1.1	1.5	1.6	1.4	1.1	-1.2	-1.5	-1.6	1.5	1.9
Leg fat percentage (right)	2.0	7.4	11.7	-0.8	-3.2	-2.9	-3.1	-3.0	-2.6	-1.8	-3.4	-2.6	-2.9	-3.0	-2.1	2.8	1.7	3.0	-3.1	-2.8
Supplements: Calcium	2.0	2.2	3.7	0.3	-1.7	-1.6	-1.6	-1.5	-1.2	0.3	-0.7	-1.9	-1.6	-1.6	-1.5	1.9	1.3	1.8	-1.7	-1.8
Crohns Disease (2017)	1.9	4.2	7.7	0.5	2.1	2.0	2.0	2.0	2.3	0.9	2.3	1.7	2.0	2.4	2.2	-1.5	-2.4	-2.8	1.9	2.4
Medication: Ramipril	1.9	2.4	6.6	-2.6	1.2	1.3	1.6	1.4	1.6	-0.3	1.1	1.1	1.3	1.2	2.0	2.2	1.8	0.8	1.8	-1.3
Falls in the last year	1.9	2.6	5.9	-1.2	1.8	1.9	1.8	1.9	2.2	-0.3	1.9	1.8	1.9	1.9	2.4	-0.8	-0.8	-0.9	1.3	0.3
Osteoarthritis (self-reported)	1.9	2.5	4.7	0.0	1.7	2.0	1.8	2.0	1.3	0.2	0.7	2.2	2.1	2.1	1.8	-0.9	-1.4	-1.7	1.5	1.3
Father’s age at death	1.8	2.4	6.3	1.2	-1.6	-1.7	-1.7	-1.7	-2.1	-0.4	-2.3	-1.8	-1.8	-1.5	-2.5	-0.2	0.5	0.6	-1.6	-0.3
Qualifications: A levels/AS levels or equivalent	1.8	3.9	6.0	0.3	2.4	2.2	2.3	2.2	1.3	-1.0	2.4	2.2	2.2	2.3	1.7	-1.3	-1.9	-2.2	2.1	2.0
Serious illness, injury or assault of a close relative in last 2 years	1.8	2.1	6.9	0.6	1.7	1.5	1.7	1.6	1.3	-0.3	1.5	1.2	1.4	1.6	1.4	-0.7	-0.5	-1.5	2.6	1.4
Blood Eosinophil Count	1.7	13.4	29.9	3.4	3.8	3.3	3.1	3.2	2.1	-0.5	2.8	3.4	3.3	3.6	3.2	-4.3	-5.5	-5.4	2.8	5.2
Medication: Metformin	1.7	2.4	5.6	-2.2	1.5	1.7	1.7	1.7	2.3	0.4	1.4	1.6	1.7	1.6	2.4	0.2	0.6	0.5	1.4	-1.2
Diabetes diagnosed by doctor	1.7	2.8	9.6	-3.1	1.2	1.6	1.5	1.6	2.3	0.5	1.3	1.5	1.6	1.3	2.5	0.6	1.1	1.3	1.6	-1.9
Guilty feelings	1.7	2.6	4.6	-0.7	1.9	2.1	2.0	2.1	1.2	-0.8	2.1	2.1	2.1	1.8	1.6	-0.3	-0.6	-0.8	2.1	0.8
Primary Biliary Cirrhosis	1.6	2.3	5.8	0.3	-1.6	-1.1	-1.3	-1.1	-2.4	-1.7	-1.9	-1.1	-1.2	-1.4	-1.9	2.3	1.3	1.5	-1.6	-1.1
Triglycerides	1.6	2.7	5.7	-0.4	1.7	1.7	1.6	1.8	2.4	1.9	1.6	1.7	1.7	1.6	1.9	-1.3	-1.0	-1.4	1.9	1.4
Emphysema/chronic bronchitis	1.6	1.8	3.2	0.3	1.8	1.6	1.6	1.5	0.7	-0.5	1.3	1.5	1.6	1.6	1.0	-1.2	-1.0	-1.3	1.8	1.1
Medication: Atorvastatin	1.6	2.0	5.8	-0.7	1.6	1.2	1.4	1.2	2.1	0.4	2.2	1.4	1.2	1.3	2.4	-0.7	-0.9	-1.0	1.6	0.7
Serious illness, injury or assault to yourself	1.5	1.8	6.2	1.1	1.3	1.2	1.3	1.2	0.4	-2.5	1.2	1.0	1.1	1.3	1.1	-0.6	-0.8	-1.6	1.9	1.6
Prospective memory result	1.5	1.8	5.1	-1.1	1.3	1.2	1.2	1.3	2.3	1.4	1.7	0.9	1.2	1.2	1.8	-1.1	-0.2	-0.6	2.2	0.5
Breastfed as a baby	1.5	1.8	2.9	-0.1	-1.7	-1.6	-1.5	-1.6	-0.5	1.2	-0.6	-1.7	-1.6	-1.5	-0.8	1.5	1.5	1.3	-1.2	-1.6
Comparative height size at age 10	1.5	8.3	20.4	-2.1	-3.0	-2.3	-2.3	-2.3	-1.7	0.0	-2.5	-2.4	-2.3	-2.7	-2.1	3.8	4.4	4.5	-2.4	-4.5
Irritable Bowel Disease (IBD)	1.4	3.3	5.3	0.4	2.0	1.9	1.9	2.1	2.3	1.5	1.9	1.3	1.8	2.1	1.8	-1.2	-1.3	-2.2	2.1	1.9
Blood Red Count	1.4	13.0	24.1	-0.0	-4.6	-4.5	-4.7	-4.5	-2.6	2.0	-4.0	-4.2	-4.5	-4.4	-3.7	2.7	1.3	2.3	-4.9	-1.6
Hand grip strength (left)	1.4	3.6	8.5	-2.2	1.8	2.0	2.1	1.9	2.9	1.7	2.5	2.4	2.1	1.8	2.3	-0.2	-0.9	-1.1	1.7	0.7
Pulse wave peak to peak time	1.4	1.6	3.6	-1.0	1.7	1.7	1.9	1.6	1.1	-0.4	0.6	1.9	1.7	1.7	1.1	-0.0	-0.1	-0.6	1.3	0.3
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	4.4	0.4	1.1	0.5	0.7	0.5	2.0	1.1	2.1	0.5	0.4	0.8	1.8	-1.5	-1.4	-1.5	0.7	1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.6	7.3	2.7	1.0	0.7	0.7	0.8	-0.2	-2.1	0.4	0.4	0.7	1.1	0.5	-1.3	-1.3	-1.8	1.1	1.7
Miserableness	1.4	2.3	4.8	0.8	1.5	1.4	1.3	1.3	1.0	-1.2	1.7	1.5	1.4	1.5	1.6	-1.6	-2.0	-2.1	1.4	2.2
Ever smoked	1.4	2.5	6.2	0.7	-1.7	-1.8	-1.6	-1.7	-1.0	0.4	-1.2	-2.5	-1.9	-1.9	-1.8	1.2	2.1	1.7	-0.5	-1.5
Relative age of first facial hair	1.3	2.7	8.3	-0.2	2.0	2.1	2.2	2.2	1.4	0.9	1.9	1.6	2.0	1.9	0.9	-0.6	0.7	-0.7	2.9	0.3
Average weekly fortified wine intake	1.3	1.5	3.8	0.3	1.6	1.1	1.2	1.2	1.3	0.6	1.4	0.8	1.0	1.3	1.3	-1.9	-0.7	-1.3	1.7	1.1
Alcohol intake versus 10 years previously	1.3	1.9	4.4	-1.2	-1.7	-1.4	-1.5	-1.4	-0.9	-0.2	-2.1	-1.0	-1.4	-1.5	-1.0	1.3	1.4	1.4	-1.9	-1.4
Gout (self-reported)	1.3	1.8	4.1	-0.2	-1.7	-1.4	-1.5	-1.4	-0.9	-0.7	-0.3	-1.7	-1.4	-1.5	-0.9	2.0	1.3	1.6	-1.5	-1.3
Leg fat mass (right)	1.3	4.9	8.3	-1.0	-2.6	-2.3	-2.5	-2.4	-1.9	-1.9	-2.8	-1.9	-2.3	-2.4	-1.5	2.5	1.0	2.4	-2.9	-2.3
Mineral and other dietary supplements	1.3	1.8	5.7	1.5	1.2	1.0	1.0	1.0	0.4	-0.1	0.9	1.0	1.0	1.3	0.6	-1.4	-1.9	-2.4	0.9	2.4
Leg fat mass (left)	1.3	5.3	9.0	-0.9	-2.8	-2.5	-2.6	-2.5	-2.0	-1.7	-2.9	-2.0	-2.4	-2.5	-1.7	2.5	1.0	2.4	-3.0	-2.3
Worry (Nagel 2018)	1.2	2.5	5.1	0.1	-1.5	-1.6	-1.5	-1.6	-2.3	-1.7	-1.5	-1.7	-1.7	-1.8	-1.4	0.9	1.6	2.0	-1.0	-1.8
Bipolar Disorder (2011)	1.2	1.1	5.2	-1.0	-0.4	-0.2	-0.2	-0.2	-0.8	-1.3	-1.0	-0.6	-0.3	-0.5	-0.5	1.0	1.6	2.3	-0.3	-2.3
Ever used hormone-replacement therapy (HRT)	1.2	1.5	2.7	1.2	-1.4	-1.6	-1.6	-1.6	-0.9	-0.2	-1.4	-1.6	-1.6	-1.4	-1.2	-0.1	-0.4	0.3	-1.6	0.1
Medication for hormone replacement therapy	1.2	1.3	3.8	1.9	-1.0	-1.3	-1.3	-1.3	-1.4	-1.5	-0.7	-1.2	-1.3	-1.0	-1.1	-0.6	-0.7	-0.6	-0.8	0.8
High blood pressure (mother)	1.2	1.6	4.4	-0.0	-1.1	-1.6	-1.5	-1.6	-1.3	-1.5	-1.3	-1.0	-1.5	-1.6	-0.5	0.3	0.2	1.1	-2.1	-1.3
Past tobacco smoking	1.2	2.2	5.5	-1.0	1.5	1.6	1.4	1.5	1.0	-0.3	1.0	2.4	1.7	1.6	1.7	-1.1	-2.1	-1.6	0.2	1.4
Medication: Cholesterol lowering	1.2	1.8	3.8	-0.0	1.6	1.5	1.5	1.5	1.2	-0.5	1.7	1.6	1.5	1.5	2.0	0.3	-0.9	-1.3	1.6	1.0
Tense / ‘highly strung’	1.2	1.9	4.5	0.0	-1.3	-1.5	-1.4	-1.5	-1.4	-1.0	-1.1	-1.6	-1.5	-1.7	-1.1	0.3	1.5	2.1	-0.9	-1.9
Medication for cholesterol, blood pressure or diabetes	1.2	2.1	7.8	1.2	1.0	1.0	0.8	0.9	0.4	1.0	1.0	0.9	1.0	1.2	0.0	-2.8	-2.5	-2.2	0.4	2.4
Hypothyroidism/myxoedema (self-reported)	1.2	2.4	6.0	-1.3	1.7	1.7	1.6	1.7	1.9	-0.3	2.1	1.8	1.7	1.7	2.4	-0.6	-0.9	-0.7	1.6	0.4
Health satisfaction	1.2	1.5	7.2	2.3	0.4	0.2	0.1	0.3	-0.3	-0.7	1.0	0.2	0.2	0.4	0.5	-0.4	-2.0	-2.4	0.9	2.7
High cholesterol (Self-reported)	1.2	2.1	5.8	-1.1	1.7	1.5	1.7	1.5	1.8	-0.4	1.5	1.7	1.6	1.4	2.4	0.0	-0.4	-0.7	2.0	0.5
Bipolar Disorder (2018)	1.1	1.7	5.9	-0.9	-1.1	-0.9	-1.0	-0.8	-0.9	-0.2	-1.6	-1.4	-1.0	-1.1	-1.3	0.5	1.8	2.4	-0.7	-2.4
LDL Cholesterol	1.1	1.7	4.9	1.1	1.3	1.1	1.0	1.1	1.3	0.4	1.2	1.1	1.1	1.3	1.4	-1.6	-1.1	-2.2	1.1	1.8
Hearing difficulty/problems: Yes	1.1	1.6	4.8	2.2	-1.1	-1.3	-1.3	-1.3	-1.9	-1.5	-0.5	-1.7	-1.4	-1.3	-1.7	-0.0	0.6	0.4	-0.8	0.1
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	2.3	-0.3	1.5	1.3	1.3	1.3	0.7	-1.3	1.2	1.4	1.4	1.1	1.5	-1.2	-0.9	-0.4	1.5	0.6
Blood clot in the leg (DVT)	1.1	1.5	3.8	-0.3	1.1	1.5	1.3	1.4	0.7	-0.1	0.3	2.0	1.6	1.7	1.2	-0.2	-1.4	-1.5	0.5	1.2
Mouth/teeth dental problems: Loose teeth	1.1	1.3	3.0	-0.4	1.2	1.2	1.3	1.2	1.7	1.2	1.2	0.9	1.1	1.2	1.4	-0.2	-0.6	-1.0	1.2	1.1
Medication: Allopurinol	1.1	1.4	3.9	-1.6	-1.2	-0.8	-0.9	-0.8	0.3	0.7	-0.3	-0.9	-0.8	-1.0	-0.2	2.0	1.4	1.8	-1.2	-1.9
Handedness (chirality/laterality): Left-handed	1.1	1.3	2.8	1.1	-1.3	-1.3	-1.3	-1.3	-1.5	-0.4	-1.1	-1.4	-1.3	-1.3	-1.7	0.4	-0.0	0.2	-1.4	0.1
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.7	-0.5	1.2	1.6	1.4	1.5	0.7	-0.1	0.3	1.9	1.6	1.7	1.3	-0.0	-1.0	-1.2	0.8	0.9
Coronary Artery Disease (CAD)	1.0	1.2	3.0	-0.2	1.2	0.9	0.9	0.9	1.3	0.1	0.8	1.2	1.0	0.9	1.6	-1.7	-1.7	-1.0	0.7	0.9
Lupus	1.0	1.5	5.2	-1.4	-0.9	-0.5	-0.7	-0.5	-0.8	1.6	-1.1	-0.6	-0.5	-0.9	-1.1	0.4	1.7	2.3	-1.2	-2.2
Vitamin and mineral supplements	1.0	1.3	2.9	-0.9	1.3	1.5	1.3	1.4	0.8	1.7	0.9	1.4	1.4	1.4	0.8	-0.7	-0.7	-0.7	0.7	0.6
Qualifications: CSEs or equivalent	1.0	1.4	5.7	-1.1	-0.8	0.0	-0.1	0.1	-0.7	-0.8	-1.4	-0.3	-0.0	-0.1	-0.6	2.4	2.1	1.8	0.1	-2.1
Medication: Levothyroxine sodium	1.0	1.6	3.3	-0.1	1.6	1.5	1.4	1.5	1.1	-1.0	1.8	1.4	1.5	1.5	1.7	-1.0	-0.9	-0.6	1.1	0.4
Heart attack	1.0	1.3	4.3	1.8	0.9	0.7	0.7	0.7	-0.1	-0.7	0.7	0.7	0.8	1.0	0.3	-1.0	-1.8	-2.0	0.8	2.1
Arm fat percentage (right)	1.0	4.1	7.1	-0.3	-2.3	-2.2	-2.3	-2.2	-2.1	-2.7	-2.4	-1.9	-2.1	-2.2	-1.4	1.7	0.7	2.1	-2.4	-1.9
Hip circumference	1.0	4.1	11.3	-2.2	-1.9	-1.3	-1.4	-1.4	-1.2	-1.3	-2.2	-1.2	-1.3	-1.6	-1.0	3.4	2.3	3.1	-1.9	-3.4
Happiness	1.0	1.3	3.8	1.0	0.8	1.0	0.9	1.0	0.8	0.6	0.8	1.1	1.1	1.2	0.9	-0.6	-1.6	-1.8	0.9	2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.6	3.5	-0.5	-1.4	-1.2	-1.3	-1.2	-1.0	-1.5	-0.5	-1.2	-1.2	-1.4	-0.5	1.7	1.1	1.8	-0.5	-1.9
Worry too long after embarrassment	1.0	1.6	4.2	1.6	1.4	1.0	1.1	1.0	0.1	-1.8	2.0	0.9	1.0	1.0	1.0	-1.6	-1.0	-1.1	1.7	1.1
Neck or shoulder pain in last month	1.0	1.4	3.7	-1.9	0.8	1.3	1.3	1.4	1.0	-0.0	0.5	1.1	1.3	1.1	1.0	1.6	1.2	0.5	1.6	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.1	2.1	1.5	-1.1	-1.2	-1.3	-1.2	-0.9	-0.1	-0.5	-1.2	-1.2	-1.1	-1.3	-0.1	-0.9	-0.6	-1.4	1.0
Age at last live birth	1.0	1.5	4.0	-1.8	-1.2	-1.0	-0.8	-1.1	-0.5	-0.1	-0.9	-0.5	-0.9	-1.1	-0.3	2.0	1.2	1.6	-1.4	-1.8
Tinnitus: Yes, now most or all of the time	1.0	1.2	2.1	-0.1	-1.1	-1.4	-1.2	-1.3	-0.7	0.8	-1.2	-1.5	-1.4	-1.3	-1.1	0.4	1.3	1.2	-0.6	-0.9
Risk taking	1.0	1.4	2.9	1.1	-1.3	-1.7	-1.4	-1.6	-1.1	-0.4	-1.1	-1.7	-1.7	-1.4	-1.0	1.1	0.7	0.5	-1.0	-0.3
Heart attack/myocardial infarction (self-reported)	1.0	1.3	4.4	1.7	0.9	0.8	0.9	0.8	-0.0	-0.6	0.7	0.8	0.9	1.1	0.4	-0.8	-1.7	-2.1	0.9	2.1
Intelligence (Savage-Jansen 2018)	0.9	2.7	6.6	-1.0	1.7	1.6	1.8	1.6	1.9	-0.7	1.9	2.3	1.6	1.6	2.6	-0.2	-0.9	-1.7	1.6	1.6
Ulcerative Colitis	0.9	1.3	3.9	-0.7	1.3	1.1	1.4	1.4	2.0	1.0	1.3	0.9	1.1	1.0	1.3	0.4	0.4	-0.7	1.8	0.5
Hypothyroidism (self reported)	0.9	2.0	6.5	-2.5	1.3	1.4	1.3	1.4	2.1	-0.0	1.3	1.6	1.4	1.3	2.5	0.3	0.0	0.1	1.1	-0.6
Number of treatments/medications taken	0.9	1.7	5.6	-1.2	-0.7	-0.9	-0.8	-0.7	0.5	-1.1	0.3	-1.2	-0.9	-1.0	1.1	1.6	2.4	2.1	0.5	-2.3
Multivitamins +/- minerals	0.9	1.2	2.3	0.4	-1.3	-1.2	-1.2	-1.2	-1.0	-1.1	-1.5	-1.0	-1.2	-1.3	-1.0	1.0	0.8	0.9	-0.9	-0.9
Chronic bronchitis/emphysema (father)	0.9	1.0	1.8	-1.0	-1.0	-0.8	-0.9	-0.7	-1.0	-0.6	-0.9	-1.0	-0.9	-1.0	-0.7	1.1	1.3	1.3	-1.1	-1.4
Number of children fathered	0.9	1.0	4.4	-1.0	-0.7	-0.2	-0.2	-0.1	-0.2	0.0	-0.8	-0.6	-0.3	-0.3	-0.5	1.8	2.1	1.7	0.2	-1.8
Ulcerative Colitis (UC)	0.8	1.4	3.1	-0.2	1.4	1.4	1.4	1.6	1.8	1.6	1.1	0.7	1.2	1.3	1.0	-0.2	0.2	-0.8	1.7	0.6
Reaction Time	0.8	1.4	3.9	0.8	-1.3	-1.1	-1.1	-1.1	-1.2	0.5	-1.0	-1.4	-1.1	-1.0	-1.2	1.7	1.1	1.1	-2.0	-1.0
HDL Cholesterol	0.8	1.3	3.2	-0.5	1.3	1.5	1.3	1.2	1.0	-0.3	1.3	1.7	1.5	1.4	1.8	-0.1	-0.6	-0.9	0.4	0.9
Chronotype (morning person)	0.8	1.9	11.5	-3.4	-0.9	-0.4	-0.4	-0.5	0.6	0.5	-1.1	-0.1	-0.4	-1.0	-0.2	1.7	1.4	2.1	-1.3	-2.2
Average weekly spirits intake	0.8	0.9	2.1	-0.1	1.5	1.1	1.2	1.1	0.8	-0.1	0.2	1.2	1.1	1.1	0.6	-1.3	-0.4	-0.9	1.3	0.9
Severe depression (siblings)	0.8	0.9	2.1	-0.3	1.5	1.2	1.2	1.2	0.8	0.1	0.2	1.0	1.1	1.0	1.0	-1.2	0.2	0.2	1.5	-0.6
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	1.9	-0.9	0.8	1.4	1.1	1.4	1.0	1.0	0.9	1.0	1.3	1.1	1.1	0.4	0.4	0.0	1.0	-0.4
Allergy	0.8	1.9	3.9	1.0	-1.4	-1.7	-1.8	-1.7	-0.6	2.0	-1.7	-1.4	-1.6	-1.4	-1.2	0.1	-0.4	-0.2	-1.9	0.2
Weight	0.8	3.9	8.1	-1.3	-2.3	-1.9	-2.0	-2.0	-1.5	-1.4	-2.4	-1.5	-1.9	-2.0	-1.3	2.8	1.3	2.3	-2.4	-2.4
Noisy workplace	0.8	1.0	2.9	-1.5	0.9	1.0	1.0	1.0	1.5	1.7	0.6	1.0	1.0	0.9	0.8	-0.4	0.7	0.3	0.9	-0.8
Exposure to tobacco smoke at home	0.8	0.9	2.6	-0.3	0.6	0.7	0.6	0.6	1.1	1.4	1.0	1.0	0.8	0.9	0.8	-0.0	-1.6	-1.5	-0.4	1.3
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	3.5	0.0	1.2	1.1	1.2	1.0	0.4	-1.4	0.5	1.7	1.2	1.2	1.3	-0.7	-1.9	-1.2	0.9	0.9
Migraine (self-reported)	0.8	1.0	5.0	-0.3	-0.7	-0.4	-0.4	-0.4	-0.9	-1.0	-0.7	-0.4	-0.4	-0.4	-0.9	2.2	1.8	1.3	-0.2	-1.6
Medication: Ibuprofen	0.8	0.9	2.8	-1.2	0.5	0.7	0.9	0.8	0.4	0.0	0.2	0.5	0.7	0.7	0.3	1.6	1.7	1.1	1.1	-1.5
Family relationship satisfaction	0.8	1.0	2.8	-0.3	1.0	0.9	1.0	0.9	1.4	0.3	1.7	0.8	0.9	0.9	1.7	-0.3	-0.8	-0.9	1.0	1.1
Commuting to job workplace: Walk	0.8	0.9	3.4	-1.4	-0.9	-0.4	-0.6	-0.4	-0.7	-0.8	-0.8	-0.2	-0.3	-0.6	-0.7	1.8	1.3	1.3	-0.4	-1.3
Medication: Aspirin	0.8	1.0	3.7	0.2	1.1	0.6	0.8	0.7	1.4	-1.0	1.9	0.4	0.6	0.8	1.9	-0.4	-0.3	-0.7	1.6	0.4
Medication: Bendroflumethiazide	0.8	1.3	4.6	0.5	-0.6	-1.5	-1.0	-1.3	0.4	-1.4	0.7	-2.2	-1.6	-1.2	0.7	0.3	1.2	1.0	0.2	-1.0
Alcohol drinker status: Never	0.8	1.0	2.2	-1.0	1.2	1.1	1.2	1.0	0.7	-1.5	0.8	1.5	1.1	1.1	1.3	-0.0	0.0	-0.4	1.0	0.0
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	1.9	0.3	1.0	1.2	1.0	1.2	0.4	-0.3	0.9	1.1	1.2	1.3	1.1	-0.0	-0.7	-1.3	1.4	1.1
Maternal smoking around birth	0.7	1.0	4.7	2.2	-0.6	-0.8	-0.9	-0.9	-1.0	0.1	-1.1	-0.8	-0.8	-0.5	-1.0	-0.6	-1.2	-1.1	-0.3	1.3
Age when periods started (menarche)	0.7	1.8	4.7	1.9	-1.6	-1.4	-1.5	-1.4	-2.2	-1.0	-1.1	-1.6	-1.4	-1.2	-1.3	0.6	0.3	0.7	-1.0	-0.8
Number of live births	0.7	1.0	3.0	0.6	-1.3	-1.2	-1.3	-1.1	-0.8	1.7	-0.5	-1.5	-1.2	-0.9	-0.8	0.5	-0.2	0.4	-1.0	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	5.7	-2.4	1.3	1.8	1.8	1.7	1.4	-0.7	1.6	2.4	1.9	1.5	1.8	0.7	-0.2	-0.1	1.3	-0.3
Arm fat mass (right)	0.7	3.0	5.4	-0.5	-2.1	-1.8	-2.0	-1.9	-1.6	-2.3	-2.1	-1.4	-1.8	-1.8	-1.1	1.9	0.4	1.6	-2.3	-1.5
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.6	0.8	1.0	0.9	0.9	1.0	1.1	0.5	1.1	0.3	0.8	1.1	0.4	-0.8	-0.4	-0.9	1.3	0.8
Illnesses of father: Heart disease	0.7	1.0	2.5	0.8	1.2	0.8	1.0	0.8	0.5	-1.6	0.9	0.8	0.8	1.0	0.8	-0.3	-0.8	-1.3	1.6	1.3
Arm fat percentage (left)	0.7	2.9	5.7	-0.3	-2.0	-1.9	-2.0	-1.9	-1.6	-2.4	-2.0	-1.6	-1.9	-1.8	-0.9	1.6	0.3	1.5	-2.2	-1.4
Ever had bowel cancer screening	0.7	0.8	2.1	1.4	-0.7	-1.1	-1.1	-1.1	-0.5	0.4	-0.3	-1.2	-1.1	-0.8	-0.6	-1.4	-0.7	-0.4	-0.5	0.4
Wears glasses or contact lenses	0.7	0.7	1.8	1.3	-0.6	-1.1	-0.9	-1.1	-0.6	-0.4	-0.7	-1.3	-1.1	-0.9	-0.7	0.1	0.7	0.6	-1.0	-0.5
Financial situation satisfaction	0.7	0.8	3.0	1.7	0.7	0.1	0.4	0.2	-0.1	-0.6	1.2	-0.1	0.0	0.4	0.5	-0.8	-1.1	-1.6	0.6	1.7
Medication: Paracetamol	0.7	1.0	4.2	-1.8	-0.6	-0.6	-0.4	-0.5	0.3	-0.7	0.3	-0.6	-0.7	-0.6	0.7	2.0	1.6	1.4	-0.1	-1.5
Irritability	0.7	1.1	4.4	-0.6	-1.1	-1.0	-0.8	-0.9	-0.9	-0.9	-1.0	-1.1	-1.0	-1.0	-0.7	2.1	1.5	1.1	-0.4	-0.9
Depressed Affect (Nagel 2018)	0.6	1.3	5.7	1.3	0.7	0.5	0.5	0.5	0.1	-2.4	1.1	0.6	0.6	0.8	1.1	-0.8	-1.5	-1.8	0.9	1.8
Prostate Cancer	0.6	0.9	7.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.6	2.8
Fasting Glucose	0.6	0.7	1.4	-0.4	0.9	1.2	1.2	1.2	0.7	-1.0	0.8	1.2	1.2	1.0	0.5	0.2	0.1	-0.3	1.0	0.2
Allergy or Eczema	0.6	1.6	5.8	-2.4	0.9	1.2	1.3	1.2	1.4	1.0	1.6	1.0	1.2	0.9	1.2	0.4	1.1	0.9	1.8	-1.1
Frequency of depressed mood in last 2 weeks	0.6	0.8	5.4	-1.8	-0.6	-0.2	-0.2	-0.2	0.3	-0.1	-0.6	0.1	-0.2	-0.3	0.3	2.3	1.1	1.1	-0.3	-1.3
Hand grip strength (right)	0.6	1.7	5.7	-2.4	0.9	1.1	1.2	1.1	2.1	1.9	1.2	1.5	1.2	1.0	1.4	0.8	0.2	0.1	1.4	-0.4
Stomach or abdominal pain in last month	0.6	0.7	2.1	0.2	0.9	0.8	0.9	0.8	0.4	-0.6	0.8	0.9	0.8	0.8	0.5	-1.0	-1.0	-1.3	0.5	1.4
Hair/balding pattern: Pattern 2	0.6	0.7	2.2	-1.2	-0.6	-0.1	-0.3	-0.1	-0.2	0.6	-1.3	-0.2	-0.2	-0.1	-0.2	1.5	1.3	1.3	-0.4	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	2.8	0.7	-0.9	-0.7	-0.8	-0.7	-1.1	-1.7	0.1	-0.8	-0.7	-0.7	-0.5	1.5	0.6	0.5	0.1	-0.6
Wheeze or whistling in the chest in last year	0.6	1.0	4.5	1.3	0.8	0.9	1.0	1.0	-0.2	-2.1	0.6	0.7	0.9	1.2	0.8	0.4	-0.6	-1.1	0.8	1.0
Medication for pain relief, constipation, heartburn	0.6	1.1	3.5	0.4	-1.1	-0.9	-1.1	-1.0	-1.6	-0.8	-1.3	-0.5	-0.8	-1.0	-1.7	-0.1	-0.5	0.1	-1.9	0.2
Mean time to correctly identify matches	0.6	1.1	3.4	0.9	-1.2	-1.1	-1.1	-1.1	-0.6	1.1	-0.5	-1.5	-1.1	-0.9	-0.8	1.1	0.8	0.8	-1.8	-0.7
Chest pain or discomfort	0.6	0.8	4.0	-0.3	0.9	0.9	1.2	0.9	0.5	-1.0	0.7	0.8	0.8	0.9	0.9	0.7	0.5	-0.4	2.0	0.3
Knee pain experienced in last month	0.6	0.9	3.2	-1.8	0.1	0.8	0.7	0.7	0.2	-0.3	-0.9	1.1	0.9	0.7	0.5	1.8	0.8	0.9	-0.1	-1.4
Average weekly red wine intake	0.6	0.8	3.4	1.0	0.9	0.9	0.7	0.9	-0.5	-1.8	0.9	0.5	0.8	0.8	0.1	-0.9	-0.8	-0.8	1.0	0.9
Mood swings	0.6	1.2	5.0	1.4	-0.9	-1.2	-1.1	-1.2	-1.5	-2.2	-0.3	-1.3	-1.2	-0.9	-0.6	0.4	-0.4	-0.1	-0.6	0.4
Loneliness, isolation	0.6	0.9	7.8	1.1	-0.8	-0.5	-0.7	-0.6	-1.3	-2.8	-0.7	-0.1	-0.5	-0.5	-0.3	0.9	-0.6	-0.4	-0.4	0.4
Medication: Gliclazide	0.6	0.7	2.0	-0.3	0.8	0.8	0.7	0.9	1.4	0.6	0.9	0.8	0.8	1.0	1.2	-0.5	-0.6	-0.8	1.0	0.6
Arm fat mass (left)	0.6	2.4	4.4	-0.5	-1.9	-1.6	-1.8	-1.7	-1.3	-1.9	-1.9	-1.2	-1.6	-1.6	-0.9	1.8	0.3	1.4	-2.1	-1.3
Average weekly champagne plus white wine intake	0.6	0.9	3.4	1.1	0.7	0.4	0.4	0.4	0.5	0.5	0.3	0.8	0.5	0.6	0.4	-1.2	-1.9	-1.7	-0.3	1.7
Ever depressed for a whole week	0.6	0.7	3.3	1.8	-0.6	-1.0	-1.1	-0.9	-0.5	-0.9	0.3	-1.2	-1.0	-0.9	-0.2	0.0	-0.5	-0.6	0.0	0.9
Heart disease (siblings)	0.6	0.7	2.0	1.0	-1.0	-0.9	-1.0	-0.8	-0.5	-0.1	-0.3	-1.4	-0.9	-1.0	-0.6	0.1	0.9	0.8	-0.9	-0.6
Major Depression (MDD)	0.5	0.7	1.8	0.5	-0.8	-0.8	-0.8	-0.8	-1.1	-0.3	-0.6	-0.9	-0.8	-0.8	-1.1	1.3	0.9	0.6	-0.1	-0.3
Ovarian Cancer	0.5	0.6	2.3	-0.5	-0.7	-0.3	-0.4	-0.3	-0.9	-0.5	-0.6	-0.5	-0.3	-0.4	-0.8	1.5	1.4	1.2	-0.1	-1.4
Fed-up feelings	0.5	0.9	2.4	0.3	0.6	0.5	0.6	0.5	0.7	-1.4	0.9	0.9	0.6	0.7	1.2	0.0	-1.6	-1.5	0.5	1.5
Mouth/teeth dental problems	0.5	0.8	3.5	-1.7	-0.3	-0.0	-0.1	-0.1	0.3	-0.9	0.8	0.4	0.1	-0.3	1.1	1.3	0.4	1.5	-0.6	-1.9
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	4.9	0.5	-0.7	-0.8	-0.7	-0.8	-1.3	-2.2	-0.8	-0.7	-0.8	-0.7	-0.6	0.7	0.1	0.5	-1.0	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.6	-1.0	0.3	0.5	0.7	0.6	0.3	0.3	-0.1	0.4	0.5	0.6	0.1	1.6	1.3	0.9	0.8	-1.3
Lung cancer (father)	0.5	0.6	1.9	-1.0	0.3	0.4	0.7	0.5	0.8	-0.1	0.0	0.2	0.4	0.5	1.0	1.4	1.1	0.8	0.4	-1.4
Peak expiratory flow (PEF)	0.5	1.1	7.5	-2.7	-0.2	0.2	0.2	0.1	0.3	-0.7	-0.3	0.9	0.3	-0.3	0.4	1.6	1.1	1.5	0.2	-1.6
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.3	0.9	-0.6	-0.5	-0.8	-0.6	-0.8	-1.5	-1.5	-0.1	-0.5	-0.5	-0.5	0.3	-1.2	-0.3	-0.5	0.5
Forced vital capacity (FVC), Best measure	0.5	1.8	7.2	-2.7	0.8	1.4	1.5	1.4	1.4	-0.2	1.4	1.6	1.4	1.0	1.4	1.3	1.0	0.7	1.3	-1.1
Age at first live birth	0.5	0.8	4.0	-1.7	-0.6	-0.3	-0.2	-0.4	-0.1	-0.5	-0.4	0.1	-0.3	-0.4	-0.2	2.0	1.2	1.3	-0.7	-1.6
Medication: Omeprazole	0.5	0.5	1.4	-0.2	0.6	0.8	0.6	0.8	0.5	-0.0	0.8	0.9	0.9	1.0	1.2	0.1	-0.7	-0.9	0.8	0.7
Number of full sisters	0.5	0.6	1.8	-0.9	0.8	0.9	0.9	0.8	0.3	-1.4	0.3	1.2	1.0	0.8	1.1	-0.0	-0.7	0.1	0.2	-0.4
Suffer from ‘nerves’	0.5	0.8	8.6	0.1	-0.4	-0.4	-0.4	-0.5	-1.0	-2.9	-0.3	-0.2	-0.4	-0.3	0.2	1.0	0.1	0.8	0.2	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.0	0.3	-0.9	-0.4	-0.6	-0.6	-1.2	-1.4	-1.2	0.1	-0.3	-0.3	-0.6	1.2	-0.5	0.1	-1.2	0.1
Medication: Aspirin	0.5	0.6	2.6	0.0	0.9	0.3	0.5	0.3	1.3	-0.7	1.5	0.1	0.3	0.4	1.6	-0.5	-0.1	-0.4	1.4	0.1
Osteoporosis (self-reported)	0.5	0.7	2.2	-0.1	0.7	0.2	0.3	0.2	1.1	0.5	1.5	0.5	0.3	0.4	1.4	-1.5	-1.2	-0.8	0.2	0.8
Illnesses of father: None of the above (group 1)	0.5	0.6	6.2	0.1	0.3	0.3	0.3	0.4	1.0	2.5	0.6	-0.1	0.3	0.4	0.2	-1.0	-0.1	-0.1	0.2	-0.2
Number of self-reported non-cancer illnesses	0.5	0.8	2.5	-0.8	-0.3	-0.6	-0.4	-0.5	-0.0	-1.5	-0.1	-0.8	-0.6	-0.6	0.7	1.4	1.6	1.4	0.0	-1.5
Commuting to job workplace: Public transport	0.5	0.6	2.4	1.1	0.4	0.0	0.1	-0.0	-0.0	-1.6	0.5	0.3	0.1	0.2	0.2	-1.0	-1.1	-1.2	-0.1	1.3
Cholesterol lowering medication	0.5	0.8	2.4	0.5	0.7	0.5	0.5	0.5	1.2	-0.9	1.3	0.5	0.5	0.6	1.6	-0.3	-0.6	-1.1	1.3	1.1
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.6	-0.9	1.1	0.8	1.0	0.8	1.1	-1.0	1.1	1.6	0.9	0.9	1.6	0.4	-0.6	-0.9	0.7	0.8
Age at First Birth	0.4	0.6	4.0	-2.0	0.1	0.3	0.4	0.3	1.0	0.7	0.4	0.3	0.3	0.2	0.5	1.1	1.0	0.8	0.0	-0.9
Mean Putamen Volume	0.4	0.5	4.0	0.4	-0.1	-0.0	-0.0	0.0	-1.2	-2.0	0.0	-0.3	-0.1	-0.0	-0.6	0.8	0.6	0.5	0.0	-0.6
Rheumatoid Arthritis	0.4	0.5	3.4	1.1	0.4	0.6	0.5	0.7	-0.4	-1.9	0.2	0.4	0.6	0.6	0.1	-0.9	-0.6	0.0	0.1	-0.2
Type 2 Diabetes (T2D) (2012)	0.4	0.4	1.8	-1.4	-0.4	-0.2	-0.0	-0.2	0.4	0.4	0.3	-0.3	-0.2	-0.2	0.6	0.6	1.0	0.9	-0.4	-1.3
Respiratory disease	0.4	0.8	5.3	-0.9	0.1	0.6	0.6	0.6	-0.9	-2.3	-0.0	0.3	0.6	0.4	-0.1	1.4	1.3	1.0	-0.1	-1.0
Townsend deprivation index at recruitment	0.4	0.6	3.2	-0.2	-0.9	-0.2	-0.4	-0.2	-0.8	-0.1	-1.1	-0.4	-0.2	-0.3	-1.0	1.8	1.0	0.7	-0.5	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	2.8	-1.3	-0.2	0.3	0.3	0.3	0.7	1.1	-0.4	0.3	0.3	0.3	0.3	1.7	1.0	0.9	0.1	-1.1
Hayfever, allergic rhinitis or eczema	0.4	0.9	2.7	-1.2	0.9	1.1	1.3	1.2	0.8	-0.2	1.4	0.7	1.1	0.9	0.7	-0.1	0.7	0.6	1.6	-0.6
Number of incorrect matches in round	0.4	0.7	2.3	0.9	-0.9	-0.4	-0.5	-0.3	-0.5	1.4	-0.2	-1.1	-0.4	-0.5	-0.9	0.6	1.5	0.9	-0.5	-0.9
Hearing difficulty/problems with background noise	0.4	0.7	2.1	-0.1	1.0	0.8	1.0	0.8	0.6	-1.1	1.4	0.9	0.9	0.8	1.3	-0.1	0.0	-0.1	0.9	0.1
Pain all over the body in last month	0.4	0.5	2.4	-0.9	-0.0	-0.1	0.1	0.0	-0.0	-0.4	-0.7	-0.2	-0.2	-0.1	0.3	0.8	1.6	1.1	0.6	-1.3
Fluid intelligence score	0.4	0.7	2.0	-0.0	0.7	0.7	0.7	0.6	0.4	-1.4	0.8	1.3	0.8	0.9	1.2	0.5	-1.1	-1.1	0.1	0.9
Mouth/teeth dental problems: Dentures	0.4	0.7	3.2	1.8	-0.7	-0.7	-0.7	-0.7	-0.8	0.9	-1.1	-1.0	-0.8	-0.5	-1.3	0.3	0.4	-0.5	-0.3	0.7
Asthma	0.4	0.7	6.7	-0.7	0.4	0.6	0.8	0.7	-0.4	-2.6	0.9	0.5	0.6	0.6	0.7	0.7	0.8	0.3	0.5	-0.3
Depression (self-reported)	0.4	0.4	1.3	-0.7	-0.7	-0.6	-0.6	-0.6	-0.5	-0.4	0.1	-0.6	-0.6	-0.7	-0.2	0.8	0.6	1.1	-0.0	-1.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.3	0.8	-0.6	-0.5	-0.6	-0.5	-0.9	0.6	-0.8	-0.9	-0.6	-0.3	-1.2	-0.8	-0.3	-0.3	-0.6	0.5
Headache pain in last month	0.4	0.7	2.2	-1.2	0.7	0.4	0.8	0.5	0.9	-0.9	1.4	0.6	0.4	0.7	1.5	0.3	-0.0	-0.6	1.0	0.4
Shortness of breath walking on level ground	0.4	0.5	2.2	0.9	0.2	0.3	0.2	0.3	-0.1	-0.6	0.5	0.3	0.3	0.4	0.3	-0.3	-1.3	-1.3	0.2	1.5
Medication: Seretide 50 evohaler	0.4	0.5	1.9	1.0	0.0	-0.4	-0.4	-0.4	-0.1	-1.2	0.8	-0.3	-0.4	-0.4	0.2	-1.4	-0.8	-0.6	-0.3	0.9
Pulse rate, automated reading	0.4	1.3	9.9	-3.1	-0.0	0.3	0.4	0.2	1.8	2.0	0.4	0.8	0.4	0.1	1.0	0.9	0.4	0.7	0.3	-1.0
Had major operations	0.4	0.5	3.0	-1.7	0.5	0.4	0.6	0.4	1.0	0.5	0.1	0.7	0.5	0.3	0.9	-0.1	0.2	0.6	0.7	-0.9
Supplements: Vitamin C	0.4	0.5	2.3	1.5	-0.5	-0.9	-0.7	-0.8	0.0	-1.2	0.4	-1.1	-0.9	-0.6	0.0	-0.4	-0.3	-0.3	0.1	0.2
Asthma (self-reported)	0.4	0.8	5.2	-0.9	0.5	0.8	0.9	0.8	-0.4	-2.3	0.8	0.6	0.8	0.7	0.7	0.8	0.9	0.5	0.4	-0.5
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.6	-1.2	-0.4	-0.2	-0.2	-0.1	0.4	-0.2	0.0	-0.3	-0.2	-0.4	0.4	1.2	1.2	1.3	0.4	-1.3
Fractured/broken bones in last 5 years	0.4	0.5	1.7	-1.0	0.4	0.5	0.6	0.6	0.9	0.2	0.4	0.3	0.5	0.6	1.1	0.6	0.8	0.2	1.3	-0.6
Pain experienced in last month	0.4	0.7	1.3	1.1	-0.5	-1.0	-0.9	-1.0	-0.3	1.1	0.1	-1.0	-1.0	-0.9	-0.5	-1.0	-1.1	-0.4	-0.8	0.6
Pack years of smoking	0.4	0.6	3.9	0.3	-0.6	-0.8	-0.7	-0.9	0.1	2.0	0.2	-0.9	-0.8	-0.7	-0.4	-0.0	-0.2	-0.2	-0.7	0.5
Depression (Nagel 2018)	0.3	0.5	3.3	-1.1	-0.3	0.1	0.0	0.0	0.6	0.3	-0.4	0.1	0.1	-0.0	0.5	1.8	1.1	0.9	-0.1	-1.2
Neuroticism (Nagel 2018)	0.3	0.6	6.7	1.0	0.2	0.0	0.1	-0.1	-0.8	-2.6	0.6	0.1	0.0	0.1	0.4	-0.3	-0.4	-0.5	0.6	0.6
Alzheimer’s Disease (in mother)	0.3	0.3	1.2	0.3	-0.2	0.3	0.0	0.1	-0.3	-1.1	0.1	0.9	0.4	0.3	0.2	0.9	-1.1	-0.5	-0.6	0.3
Alzheimer’s Disease (in father)	0.3	0.3	1.0	1.0	0.3	0.5	0.4	0.5	-0.2	-0.7	0.2	0.7	0.6	0.6	0.1	-0.3	-0.7	-0.7	0.0	0.4
Alzheimer’s Disease (including proxy)	0.3	0.4	1.6	0.5	-0.4	0.3	-0.1	0.1	-0.4	-1.0	-0.0	0.9	0.4	0.3	0.1	1.3	-0.9	-0.3	-0.9	-0.1
Neuroticism (2016)	0.3	0.5	3.8	-0.7	-0.2	-0.1	-0.1	-0.2	-0.6	-2.0	0.3	-0.0	-0.1	-0.2	0.4	1.1	0.8	0.7	0.2	-0.9
Neuroticism	0.3	0.8	9.2	0.1	0.5	0.4	0.5	0.4	-0.1	-3.0	1.0	0.6	0.4	0.4	1.1	0.3	-0.6	-0.5	0.6	0.5
Hair Pigment	0.3	8.8	15.3	1.2	-3.1	-3.7	-3.7	-3.7	-3.2	0.6	-3.7	-3.5	-3.7	-3.8	-3.4	1.1	0.9	1.9	-3.9	-1.2
Tanning	0.3	4.0	7.1	-2.0	2.1	2.3	2.3	2.3	2.7	1.3	1.4	2.6	2.3	2.3	2.4	-0.3	-1.1	-1.5	2.0	1.1
Sensitivity / hurt feelings	0.3	0.5	3.7	0.8	-0.4	-0.7	-0.7	-0.7	-0.9	-1.9	0.2	-0.5	-0.7	-0.5	0.1	-0.4	-0.9	-0.1	-0.5	0.0
Angina	0.3	0.4	1.6	0.0	0.8	0.6	0.7	0.7	0.4	0.6	0.0	0.5	0.6	0.7	0.5	-0.2	0.2	-0.6	1.3	0.6
Supplements: Zinc	0.3	0.3	0.9	-0.5	0.2	0.2	0.1	0.2	0.9	0.8	0.9	0.3	0.2	0.1	0.7	-0.6	-0.8	-0.4	-0.1	0.5
Pack years adult smoking proportion	0.3	0.4	5.0	-0.0	-0.3	-0.5	-0.4	-0.5	0.5	2.2	0.4	-0.6	-0.5	-0.4	-0.1	-0.0	-0.2	-0.2	-0.4	0.4
Nervous feelings	0.3	0.6	3.2	0.4	-0.6	-0.7	-0.7	-0.7	-1.3	-1.8	-0.4	-0.7	-0.8	-0.8	-0.7	-0.2	0.4	0.7	-0.0	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	4.1	0.8	-0.3	-0.0	-0.1	0.0	-1.2	-2.0	-0.7	-0.0	-0.0	-0.2	-0.5	1.0	0.4	0.1	0.0	-0.0
Had other major operations	0.3	0.4	4.4	-0.8	-0.5	-0.4	-0.4	-0.4	0.7	2.1	0.2	-0.1	-0.4	-0.3	0.1	0.6	0.4	0.1	-0.3	-0.1
Forced vital capacity (FVC)	0.3	1.0	3.2	-1.8	0.7	1.1	1.2	1.1	1.0	-0.6	1.2	1.3	1.2	0.8	1.0	0.9	0.6	0.3	0.9	-0.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.5	1.2	-0.3	-0.6	-0.6	-0.5	-0.1	-1.1	0.6	-0.7	-0.7	-0.4	0.5	-0.4	-0.7	-0.6	0.3	0.7
Time employed in main current job	0.3	0.3	1.7	-0.1	0.1	-0.1	-0.2	-0.2	0.6	0.5	0.3	0.5	-0.0	-0.1	0.5	-0.7	-1.1	-1.0	-0.5	1.3
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	4.4	-2.1	0.7	1.1	1.1	1.0	0.7	-0.4	0.9	1.7	1.2	0.7	1.0	0.7	-0.1	0.2	0.6	-0.4
Length of working week for main job	0.3	0.3	1.6	1.2	-0.1	-0.1	-0.1	-0.1	-0.3	0.0	-1.0	0.0	-0.1	-0.0	-0.6	0.1	-0.4	-1.0	-0.2	1.0
Medication: Paracetamol	0.3	0.5	2.1	-1.3	-0.4	-0.5	-0.2	-0.4	0.4	-0.1	0.1	-0.6	-0.5	-0.4	0.5	1.4	1.2	1.0	0.1	-1.0
Glaucoma (self-reported)	0.3	0.4	1.9	0.1	0.5	0.4	0.5	0.4	0.5	-0.8	1.4	0.5	0.4	0.3	1.2	-0.0	-0.3	-0.5	0.4	0.3
Exposure to tobacco smoke outside home	0.3	0.4	1.0	1.0	-0.8	-0.7	-0.7	-0.7	-0.5	-0.3	-0.7	-1.0	-0.8	-0.4	-0.7	0.9	0.0	-0.2	-0.5	0.3
Angina (self-reported)	0.3	0.4	1.7	0.2	0.8	0.7	0.8	0.7	0.2	0.1	0.1	0.5	0.6	0.8	0.5	-0.3	0.1	-0.8	1.3	0.7
Heart disease (mother)	0.3	0.4	1.6	0.9	0.5	-0.2	0.1	-0.1	0.6	-0.3	0.8	-0.7	-0.3	-0.0	0.5	-1.3	-0.2	-0.7	0.8	0.7
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.9	0.4	-0.5	-0.6	-0.4	-0.6	-0.7	-0.3	-0.1	-0.8	-0.7	-0.6	-0.6	0.9	0.3	0.4	-0.2	-0.2
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	2.0	-0.5	0.6	0.2	0.3	0.2	0.6	1.2	0.5	0.3	0.2	0.1	0.3	-1.4	-0.0	0.3	0.3	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.6	-0.9	0.2	0.3	0.3	0.4	0.2	-0.4	-0.0	0.2	0.3	0.3	0.8	0.8	1.0	1.0	0.6	-1.2
Long-standing illness, disability or infirmity	0.3	0.4	1.1	-0.8	0.7	0.7	0.6	0.8	0.9	-0.2	0.7	0.3	0.6	0.6	1.0	0.1	0.3	-0.3	1.1	0.3
Eye problems/disorders: Cataract	0.3	0.3	1.4	0.1	-0.2	-0.1	-0.4	-0.3	-0.4	-0.4	-1.1	0.5	-0.1	-0.3	-0.2	-0.8	-0.8	-0.3	-1.2	0.3
Breast cancer (self-reported)	0.3	0.4	1.2	0.0	0.7	0.8	0.7	0.7	-0.1	-0.9	1.1	0.6	0.8	0.7	0.4	-0.5	-0.1	-0.2	0.3	-0.1
Ever taken oral contraceptive pill	0.3	0.4	1.7	-0.2	-0.5	-0.4	-0.4	-0.4	-0.6	-1.3	-0.3	-0.6	-0.5	-0.6	-0.4	0.8	0.8	0.6	-0.0	-0.5
Number of operations (self-reported)	0.3	0.4	1.1	-0.1	-0.7	-1.0	-0.9	-1.0	-0.3	0.2	-0.5	-0.8	-1.0	-1.0	-0.5	-0.0	0.2	0.2	-0.6	-0.0
Age started oral contraceptive pill	0.3	0.3	1.3	0.4	-0.0	0.0	-0.0	0.0	0.6	0.8	1.1	-0.1	0.0	0.2	0.4	-0.3	-0.9	-1.0	-0.1	1.1
Unable to work because of sickness or disability	0.3	0.3	3.9	-0.9	0.0	-0.2	-0.2	-0.1	0.6	2.0	0.1	-0.3	-0.2	-0.4	0.3	-0.4	0.2	0.3	-0.1	-0.2
Myopia	0.3	0.4	4.0	1.1	0.4	-0.1	0.0	-0.1	-0.7	-2.0	0.3	-0.0	-0.1	-0.1	0.2	-0.7	-0.6	-0.2	-0.2	0.4
BMI	0.2	1.2	7.3	-0.4	0.1	0.2	-0.0	-0.0	0.2	-1.9	-0.1	1.0	0.3	0.4	0.9	0.4	-2.7	-1.7	-0.8	1.7
Smoking Status	0.2	0.4	2.0	0.9	0.6	0.5	0.7	0.6	0.6	0.2	1.0	-0.0	0.4	0.6	0.3	0.2	0.2	-0.3	1.4	0.2
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.9	-0.1	0.5	0.3	0.4	0.4	0.5	-0.7	0.6	0.2	0.2	0.3	0.6	0.2	0.0	-0.8	0.8	1.0
Diabetes (father)	0.2	0.2	0.7	-0.5	0.2	0.4	0.4	0.4	-0.2	-0.8	0.2	0.6	0.5	0.2	0.2	0.5	-0.1	-0.3	0.6	0.5
Taking other prescription medications	0.2	0.3	1.7	0.0	0.3	0.1	0.2	0.2	0.5	-0.9	1.0	-0.1	0.1	0.2	1.3	0.5	0.6	-0.1	0.8	-0.1
Had menopause	0.2	0.2	0.8	0.8	-0.1	-0.4	-0.4	-0.5	-0.1	0.2	0.3	-0.3	-0.4	-0.0	0.4	-0.2	-0.9	-0.7	-0.5	0.8
Neuroticism score	0.2	0.5	5.4	0.0	-0.3	-0.4	-0.2	-0.4	-0.6	-2.3	0.3	-0.2	-0.4	-0.3	0.4	0.9	0.2	0.3	0.3	-0.2
Worrier / anxious feelings	0.2	0.3	0.9	-0.6	-0.3	-0.2	-0.2	-0.2	-0.9	-0.6	-0.2	-0.1	-0.2	-0.5	-0.2	0.9	0.5	0.9	-0.3	-0.9
Pulse rate	0.2	0.4	3.8	-1.9	0.2	0.3	0.4	0.3	0.9	0.4	0.2	0.5	0.4	0.1	0.5	0.4	0.0	0.5	0.2	-0.6
Birth weight	0.2	0.4	2.7	1.6	-0.1	-0.2	-0.2	-0.2	0.1	0.8	0.4	-0.2	-0.2	0.1	-0.1	-0.1	-0.9	-1.0	0.0	1.0
Alcohol intake frequency.	0.2	0.5	2.9	-0.1	-0.7	-0.4	-0.4	-0.4	-0.9	-1.5	-0.7	-0.2	-0.4	-0.3	-0.4	1.7	0.6	0.2	-0.7	-0.4
Illnesses of siblings: Diabetes	0.2	0.2	0.7	-0.6	0.4	0.5	0.6	0.5	0.7	-0.1	0.5	0.5	0.5	0.6	0.8	0.0	-0.0	-0.1	0.4	0.1
Pain type(s) experienced in last month: Hip pain	0.2	0.2	1.0	0.3	0.2	0.2	0.1	0.2	0.6	-0.7	0.5	0.2	0.2	0.4	1.0	0.3	-0.7	-0.7	-0.3	0.5
Medication: Lisinopril	0.2	0.3	0.8	0.2	-0.3	-0.8	-0.5	-0.6	0.1	-0.4	-0.2	-0.9	-0.8	-0.7	0.3	0.3	0.6	0.6	-0.2	-0.8
Commuting to job workplace: Cycle	0.2	0.2	0.8	0.6	-0.5	-0.1	-0.3	-0.1	-0.5	0.4	0.2	-0.4	-0.2	-0.2	-0.9	0.7	0.5	-0.2	-0.1	0.4
Basal cell carcinoma (self-reported)	0.2	0.3	1.1	0.7	0.1	0.2	0.0	0.2	-0.8	-0.0	-1.1	0.2	0.2	0.2	-0.7	-0.9	-0.6	0.3	-0.3	-0.4
Arm predicted mass (left)	0.2	0.8	4.1	-1.7	-0.8	-0.5	-0.5	-0.6	0.1	0.5	-1.1	-0.0	-0.4	-0.5	-0.3	2.0	0.5	0.8	-1.1	-1.0
Body Mass Index (BMI) (2010)	0.1	0.1	0.7	-0.8	0.1	0.2	0.3	0.1	0.3	-0.2	-0.2	0.6	0.2	0.2	0.6	0.5	-0.2	0.0	0.1	-0.2
Waist Hip Ratio (WHR)	0.1	0.6	2.3	0.8	0.3	0.0	0.1	0.0	0.0	1.5	-0.9	0.5	0.1	0.3	0.0	-1.2	-1.2	-1.4	0.2	1.4
Lung FEV1/FVC ratio	0.1	0.7	4.1	0.7	-0.3	-0.3	-0.7	-0.5	-1.1	-0.5	-0.7	0.5	-0.1	-0.2	-0.4	-0.6	-2.0	-1.3	-0.9	1.4
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	1.1	0.3	-0.1	0.1	-0.1	0.1	0.5	1.0	-0.2	-0.0	0.1	-0.0	0.2	0.3	0.1	0.4	-0.3	-0.4
Diabetes (mother)	0.1	0.1	0.5	-0.1	-0.0	-0.4	-0.3	-0.4	0.5	-0.3	0.1	-0.2	-0.3	-0.2	0.7	-0.5	-0.4	0.1	-0.7	-0.1
Leg fat-free mass (left)	0.1	0.6	1.5	-0.8	0.5	0.6	0.6	0.5	0.7	-1.2	0.4	1.1	0.7	0.6	1.0	0.7	-1.1	-0.7	-0.1	0.4
Supplements: Glucosamine	0.1	0.1	0.7	-0.9	0.1	0.2	0.2	0.1	0.4	-0.0	-0.0	0.3	0.2	0.2	0.2	-0.3	0.4	0.5	0.1	-0.7
Body mass index (BMI)	0.1	0.5	3.4	-0.2	0.0	-0.0	-0.1	-0.1	0.2	-1.4	-0.4	0.6	0.0	0.2	0.7	0.1	-1.8	-1.1	-0.6	1.0
Leg predicted mass (left)	0.1	0.6	1.6	-0.8	0.5	0.6	0.5	0.4	0.7	-1.2	0.4	1.1	0.7	0.6	1.0	0.7	-1.2	-0.7	-0.2	0.4
Waist circumference	0.1	0.5	2.4	-0.6	-0.8	-0.7	-0.8	-0.7	-0.3	-0.5	-1.5	-0.3	-0.6	-0.6	-0.1	1.3	-0.1	0.5	-0.9	-0.7
Medication: Simvastatin	0.1	0.2	0.8	0.4	-0.0	-0.2	-0.2	-0.2	0.1	-0.7	-0.0	-0.2	-0.2	-0.2	0.6	0.9	0.4	-0.1	0.7	0.0
Trunk fat-free mass	0.1	0.5	2.3	-1.5	0.3	0.5	0.5	0.3	1.1	0.5	0.3	1.1	0.6	0.5	0.7	1.2	-0.3	-0.4	-0.0	0.0
Trunk predicted mass	0.1	0.5	2.3	-1.5	0.3	0.5	0.5	0.4	1.1	0.5	0.3	1.1	0.6	0.5	0.7	1.1	-0.3	-0.4	0.0	0.0
Medication: Ventolin 100micrograms inhaler	0.1	0.2	1.0	-1.0	-0.1	-0.0	0.1	0.1	0.2	0.1	-0.7	-0.1	-0.1	-0.1	-0.2	-0.2	0.8	0.6	0.2	-0.4
Arm fat-free mass (right)	0.1	0.5	2.9	-1.7	-0.1	0.1	0.1	-0.0	0.9	0.7	-0.3	0.7	0.2	0.1	0.5	1.6	-0.3	-0.2	-0.6	-0.2
Number of full brothers	0.1	0.1	0.9	-0.4	-0.3	0.1	-0.2	0.1	0.1	0.2	0.1	0.1	0.1	-0.1	0.1	0.6	-0.2	0.2	-1.0	-0.1
Eye problems/disorders: None of the above	0.1	0.1	0.4	-0.3	-0.1	-0.3	-0.2	-0.2	-0.4	-0.6	0.6	-0.6	-0.3	-0.1	-0.3	-0.1	-0.0	0.0	0.2	0.1
Arm predicted mass (right)	0.1	0.4	2.8	-1.7	-0.3	-0.1	-0.1	-0.2	0.7	0.6	-0.5	0.5	0.0	-0.1	0.4	1.5	-0.2	-0.0	-0.8	-0.3
Overall health rating	0.1	0.3	1.8	-0.0	-0.0	0.2	0.2	0.2	-0.6	-1.4	-0.6	0.2	0.2	0.1	0.1	1.2	0.4	0.3	0.2	-0.5
Whole body fat-free mass	0.1	0.4	1.7	-1.3	0.2	0.4	0.4	0.3	0.9	-0.1	0.2	0.9	0.5	0.4	0.7	1.1	-0.6	-0.4	-0.2	0.1
Leg fat-free mass (right)	0.1	0.7	1.7	-0.7	0.6	0.7	0.7	0.6	0.9	-1.0	0.6	1.2	0.8	0.8	1.1	0.6	-1.3	-0.9	-0.1	0.5
Back pain experienced in last month	0.1	0.2	0.9	-0.3	0.1	0.2	0.2	0.3	0.8	0.8	-0.2	0.2	0.2	0.3	0.3	0.9	0.5	-0.1	0.3	0.0
Whole body water mass	0.1	0.5	1.9	-1.4	0.3	0.5	0.5	0.3	1.0	0.0	0.3	1.0	0.6	0.5	0.8	1.1	-0.6	-0.5	-0.1	0.1
Leg predicted mass (right)	0.1	0.6	1.6	-0.7	0.6	0.7	0.7	0.6	0.8	-1.0	0.6	1.2	0.8	0.8	1.0	0.6	-1.3	-0.9	-0.1	0.5
Eye problems/disorders: Glaucoma	0.1	0.2	0.6	-0.4	0.2	-0.0	0.2	-0.0	0.2	-0.8	0.8	0.2	-0.0	-0.1	0.7	0.4	0.5	0.0	0.4	-0.1
Basal metabolic rate	0.1	0.4	2.8	-1.3	-0.5	-0.3	-0.3	-0.4	0.2	-0.5	-0.5	0.3	-0.2	-0.3	0.1	1.7	-0.1	0.3	-0.9	-0.6
Arm fat-free mass (left)	0.1	0.7	3.7	-1.5	-0.8	-0.5	-0.5	-0.6	-0.0	0.3	-1.1	0.1	-0.4	-0.5	-0.4	1.9	0.3	0.6	-1.1	-0.8
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

ATF1

Models

Trait associations