[Hub]/) : Traits : Trunk fat mass : ← →

chr17:40,009,690-41,538,783

Best TWAS P=7.97e-12 · Best GWAS P=7.38e-09 conditioned to 0.112

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	MLX	0.03	0.03	enet	12	0.02	6.5e-04	-5.3	-5.5	3.4e-08	-0.54	0.18	0.74	FALSE
2	CommonMind	Brain Pre-frontal Cortex	TUBG2	0.14	0.25	lasso	3	0.25	1.1e-29	-5.7	-5.7	9.1e-09	-0.57	0.02	0.98	FALSE
3	GTEx	Adipose Subcutaneous	TUBG2	0.21	0.18	enet	17	0.26	2.1e-21	-5.2	-5.9	3.2e-09	-0.75	0.05	0.95	FALSE
4	GTEx	Adipose Subcutaneous	HSD17B1	0.06	0.07	enet	5	0.06	6.8e-06	-5.7	-5.7	1.2e-08	-0.58	0.02	0.98	FALSE
5	GTEx	Artery Aorta	HSD17B1	0.06	0.05	enet	11	0.02	4.7e-02	-5.7	-5.4	5.3e-08	-0.54	0.03	0.89	FALSE
6	GTEx	Artery Tibial	TUBG2	0.25	0.22	enet	23	0.23	3.0e-18	-5.7	-5.3	1.0e-07	-0.64	0.03	0.97	FALSE
7	GTEx	Artery Tibial	HSD17B1	0.12	0.07	lasso	9	0.07	4.4e-06	-5.7	-5.8	5.1e-09	-0.60	0.02	0.98	FALSE
8	GTEx	Artery Tibial	RP11-400F19.6	0.07	0.01	lasso	5	0.01	3.0e-02	5.8	-5.6	2.1e-08	-0.97	0.02	0.96	FALSE
9	GTEx	Brain Caudate basal ganglia	TUBG2	0.39	0.24	enet	45	0.25	7.7e-08	-5.6	-6.8	8.0e-12	-0.67	0.03	0.97	TRUE
10	GTEx	Brain Cerebellum	TUBG2	0.18	0.11	enet	10	0.07	4.0e-03	-5.7	-5.4	6.5e-08	-0.73	0.03	0.95	FALSE
11	GTEx	Brain Cerebellum	HSD17B1P1	0.17	0.16	lasso	4	0.20	1.7e-06	-5.2	-5.5	3.4e-08	-0.48	0.04	0.94	FALSE
12	GTEx	Brain Cortex	TUBG2	0.36	0.36	enet	15	0.32	1.1e-09	-5.7	-5.8	7.7e-09	-0.60	0.03	0.97	FALSE
13	GTEx	Brain Frontal Cortex BA9	TUBG2	0.33	0.26	lasso	4	0.18	1.9e-05	-5.7	-5.9	3.7e-09	-0.56	0.03	0.97	FALSE
14	GTEx	Brain Hippocampus	TUBG2	0.40	0.18	lasso	8	0.20	1.8e-05	-5.6	-5.4	6.8e-08	-0.57	0.03	0.89	FALSE
15	GTEx	Brain Putamen basal ganglia	TUBG2	0.17	0.12	lasso	5	0.09	3.7e-03	-5.7	-5.7	1.2e-08	-0.58	0.03	0.86	FALSE
16	GTEx	Breast Mammary Tissue	TUBG2	0.15	0.06	enet	18	0.08	4.5e-05	-4.9	-5.5	3.4e-08	-0.71	0.11	0.88	FALSE
17	GTEx	Cells Transformed fibroblasts	TUBG2	0.16	0.18	lasso	4	0.17	6.5e-13	-5.7	-5.9	4.4e-09	-0.66	0.02	0.98	FALSE
18	GTEx	Cells Transformed fibroblasts	MLX	0.04	0.03	enet	8	0.00	3.3e-01	-5.6	-5.6	1.8e-08	-0.61	0.03	0.90	FALSE
19	GTEx	Colon Sigmoid	TUBG2	0.16	0.04	lasso	5	0.05	6.7e-03	-5.2	-5.5	3.9e-08	-0.56	0.04	0.85	FALSE
20	GTEx	Colon Transverse	HSD17B1P1	0.14	0.11	lasso	4	0.09	3.8e-05	-5.0	-5.3	1.0e-07	-0.58	0.04	0.96	FALSE
21	GTEx	Colon Transverse	HSD17B1	0.15	0.14	lasso	11	0.12	1.7e-06	-5.7	-5.7	1.5e-08	-0.59	0.02	0.98	FALSE
22	GTEx	Esophagus Gastroesophageal Junction	TUBG2	0.15	0.10	enet	18	0.12	3.7e-05	-5.1	-5.3	1.5e-07	-0.66	0.06	0.87	FALSE
23	GTEx	Esophagus Mucosa	TUBG2	0.09	0.09	lasso	4	0.11	5.5e-08	-5.7	-6.4	1.2e-10	-0.84	0.03	0.97	FALSE
24	GTEx	Esophagus Mucosa	HSD17B1P1	0.04	0.06	lasso	5	0.05	1.9e-04	-5.7	-5.7	1.2e-08	-0.59	0.03	0.96	FALSE
25	GTEx	Esophagus Muscularis	TUBG2	0.14	0.16	enet	17	0.06	2.1e-04	-5.7	-5.9	3.0e-09	-0.66	0.03	0.97	FALSE
26	GTEx	Esophagus Muscularis	HSD17B1	0.08	0.04	lasso	4	0.06	2.2e-04	-5.7	5.6	1.6e-08	0.57	0.02	0.96	FALSE
27	GTEx	Heart Atrial Appendage	TUBG2	0.07	0.05	lasso	2	0.02	2.9e-02	-5.3	-5.6	2.4e-08	-0.57	0.04	0.85	FALSE
28	GTEx	Lung	TUBG2	0.08	0.02	enet	8	0.04	7.8e-04	-5.7	-5.6	1.7e-08	-0.74	0.04	0.90	FALSE
29	GTEx	Lung	CNTNAP1	0.06	0.00	enet	16	0.02	1.5e-02	-4.9	5.3	9.2e-08	0.69	0.05	0.69	FALSE
30	GTEx	Nerve Tibial	TUBG2	0.26	0.28	enet	39	0.28	2.2e-20	-5.2	-5.7	1.0e-08	-0.75	0.14	0.86	FALSE
31	GTEx	Pancreas	CNTNAP1	0.13	0.09	lasso	7	0.09	9.1e-05	4.0	5.2	2.0e-07	0.82	0.11	0.72	FALSE
32	GTEx	Skin Not Sun Exposed Suprapubic	TUBG2	0.15	0.13	lasso	5	0.12	4.0e-07	5.8	-5.9	3.1e-09	-0.99	0.02	0.98	FALSE
33	GTEx	Skin Not Sun Exposed Suprapubic	TUBG1	0.11	0.01	lasso	6	0.00	1.7e-01	4.2	-5.3	1.4e-07	-0.71	0.05	0.65	FALSE
34	GTEx	Skin Sun Exposed Lower leg	TUBG2	0.14	0.10	enet	25	0.12	4.9e-10	-5.7	-6.1	1.2e-09	-0.83	0.02	0.98	FALSE
35	GTEx	Skin Sun Exposed Lower leg	TUBG1	0.04	0.06	lasso	1	0.05	8.3e-05	-5.7	5.7	9.1e-09	0.59	0.03	0.95	FALSE
36	GTEx	Stomach	HSD17B1P1	0.10	0.04	lasso	3	0.04	6.9e-03	4.0	-5.8	6.8e-09	-0.76	0.04	0.76	FALSE
37	GTEx	Testis	TUBG1	0.12	0.09	enet	18	0.08	1.8e-04	-5.2	-5.3	9.1e-08	-0.57	0.05	0.94	FALSE
38	GTEx	Thyroid	TUBG2	0.19	0.21	lasso	7	0.20	3.5e-15	-5.2	-5.5	3.7e-08	-0.64	0.22	0.78	FALSE
39	GTEx	Thyroid	HSD17B1P1	0.04	0.00	enet	9	0.00	2.2e-01	-5.7	-6.2	4.3e-10	-0.74	0.03	0.87	FALSE
40	GTEx	Thyroid	CNTNAP1	0.06	0.06	enet	12	0.06	3.5e-05	-5.7	5.6	2.2e-08	0.55	0.03	0.97	FALSE
41	GTEx	Thyroid	CTD-3193K9.3	0.05	0.02	enet	8	0.02	5.1e-03	-5.7	5.5	4.8e-08	0.50	0.03	0.94	FALSE
42	METSIM	Adipose	HSD17B1	0.08	0.08	lasso	6	0.06	3.1e-09	-5.7	-5.7	1.1e-08	-0.58	0.02	0.98	FALSE
43	METSIM	Adipose	TUBG2	0.08	0.09	lasso	6	0.09	5.2e-13	4.2	-5.5	4.7e-08	-0.79	0.44	0.55	FALSE
44	NTR	Blood	TUBG2	0.01	0.00	blup	247	0.01	4.0e-03	-4.9	6.7	2.3e-11	0.39	0.04	0.92	FALSE
45	The Cancer Genome Atlas	Breast Invasive Carcinoma	TUBG2	0.02	0.01	lasso	2	0.01	1.7e-02	4.9	-5.6	2.0e-08	-0.86	0.01	0.36	FALSE
46	The Cancer Genome Atlas	Colon Adenocarcinoma	CNTNAP1	0.06	0.05	blup	27	0.03	7.3e-03	-5.1	5.7	1.1e-08	0.55	0.02	0.87	FALSE
47	The Cancer Genome Atlas	Colon Adenocarcinoma	HSD17B1	0.03	0.01	blup	30	0.01	1.5e-01	-5.7	-5.7	9.9e-09	-0.61	0.01	0.72	FALSE
48	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	HSD17B1	0.06	0.04	lasso	5	0.06	4.0e-07	-5.7	-5.2	1.7e-07	-0.52	0.02	0.98	FALSE
49	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TUBG2	0.08	0.05	blup	29	0.07	3.5e-08	-5.6	-5.4	5.9e-08	-0.60	0.01	0.99	FALSE
50	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	HSD17B1	0.05	0.05	enet	25	0.04	1.4e-03	-5.7	-5.2	1.9e-07	-0.66	0.02	0.94	FALSE
51	The Cancer Genome Atlas	Brain Lower Grade Glioma	HSD17B1	0.30	0.05	enet	14	0.06	2.8e-07	-5.2	-5.8	5.6e-09	-0.71	0.03	0.97	FALSE
52	The Cancer Genome Atlas	Brain Lower Grade Glioma	TUBG2	0.07	0.12	enet	14	0.12	5.9e-13	-5.7	-5.6	1.9e-08	-0.58	0.01	0.99	FALSE
53	The Cancer Genome Atlas	Lung Adenocarcinoma	CNTNAP1	0.06	0.05	lasso	1	0.04	6.8e-06	-5.2	5.2	2.3e-07	0.54	0.05	0.94	FALSE
54	The Cancer Genome Atlas	Lung Adenocarcinoma	RND2	0.08	0.00	enet	16	0.02	3.5e-03	-3.8	5.2	2.1e-07	0.06	0.00	0.01	FALSE
55	The Cancer Genome Atlas	Lung Adenocarcinoma	TUBG2	0.07	0.01	enet	7	0.02	2.2e-03	4.9	-5.4	6.9e-08	-0.80	0.01	0.45	FALSE
56	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PSMC3IP	0.02	0.02	blup	33	0.02	9.8e-04	-5.7	-6.1	8.8e-10	-0.78	0.02	0.87	FALSE
57	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TUBG2	0.02	0.01	blup	29	0.02	4.5e-03	4.1	-5.6	2.0e-08	-0.63	0.01	0.61	FALSE
58	The Cancer Genome Atlas	Prostate Adenocarcinoma	CNTNAP1	0.06	0.04	blup	27	0.04	8.9e-05	-5.2	5.4	5.7e-08	0.62	0.06	0.90	FALSE
59	The Cancer Genome Atlas	Prostate Adenocarcinoma	HSD17B1	0.02	0.03	blup	30	0.03	4.0e-04	-5.2	-5.7	1.1e-08	-0.66	0.04	0.93	FALSE
60	The Cancer Genome Atlas	Prostate Adenocarcinoma	TUBG2	0.04	0.02	blup	29	0.02	1.5e-03	-5.7	-6.2	6.9e-10	-0.70	0.01	0.89	FALSE
61	The Cancer Genome Atlas	Thyroid Carcinoma	CNTNAP1	0.04	0.03	blup	27	0.05	2.7e-05	-5.3	5.8	5.7e-09	0.55	0.04	0.94	FALSE
62	The Cancer Genome Atlas	Thyroid Carcinoma	HSD17B1	0.05	0.07	blup	29	0.07	2.3e-07	-5.0	-6.0	2.0e-09	-0.76	0.10	0.90	FALSE
63	The Cancer Genome Atlas	Thyroid Carcinoma	TUBG2	0.20	0.13	blup	29	0.17	1.7e-16	4.9	-5.5	3.9e-08	-0.84	0.06	0.94	FALSE