[Hub]/) : Traits : Trunk fat mass :

chr3:93,537,290-94,472,527

Best TWAS P=1.72e-10 · Best GWAS P=1.02e-16 conditioned to 2.62e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Heart Atrial Appendage PROS1 0.31 0.16 enet 7 0.19 8.4e-09 6.0 -5.5 4.7e-08 -0.68 0.96 0.02 FALSE
2 METSIM Adipose STX19 0.06 0.09 lasso 3 0.08 1.8e-11 5.8 6.2 6.8e-10 0.50 1.00 0.00 FALSE
3 YFS Blood DHFRL1 0.07 0.04 lasso 9 0.04 4.1e-14 6.5 5.9 4.7e-09 0.54 1.00 0.00 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma DHFRL1 0.07 0.05 lasso 1 0.05 3.4e-11 5.8 -5.8 7.8e-09 -0.43 0.36 0.64 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma STX19 0.04 0.02 lasso 1 0.01 5.5e-04 5.9 5.9 4.3e-09 0.64 0.02 0.77 FALSE
6 The Cancer Genome Atlas Glioblastoma Multiforme DHFRL1 0.20 0.12 lasso 8 0.11 3.7e-04 5.8 -5.8 5.0e-09 -0.44 0.01 0.10 FALSE
7 The Cancer Genome Atlas Glioblastoma Multiforme STX19 0.52 -0.01 enet 15 0.17 5.6e-06 5.9 5.4 7.5e-08 0.30 0.00 0.16 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DHFRL1 0.07 0.05 enet 17 0.05 2.5e-06 5.8 -6.3 3.2e-10 -0.54 0.04 0.92 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DHFRL1 0.13 0.07 lasso 2 0.07 5.7e-08 5.8 -5.8 7.8e-09 -0.43 0.36 0.63 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma STX19 0.35 0.11 enet 12 0.20 2.4e-22 5.9 6.4 1.7e-10 0.49 0.04 0.96 TRUE
11 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma STX19 0.60 0.12 enet 25 0.36 2.4e-21 5.9 5.3 1.4e-07 0.33 0.01 0.99 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma DHFRL1 0.10 0.06 lasso 2 0.05 5.2e-06 5.8 -5.8 7.8e-09 -0.43 0.36 0.63 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma STX19 0.51 0.13 enet 19 0.34 3.9e-40 5.9 5.5 3.4e-08 0.40 0.28 0.72 FALSE
14 The Cancer Genome Atlas Liver Hepatocellular Carcinoma STX19 0.15 0.08 lasso 1 0.05 1.8e-03 5.9 5.9 4.3e-09 0.64 0.02 0.56 FALSE
15 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma STX19 0.28 -0.01 enet 15 0.08 6.4e-04 5.9 5.8 5.1e-09 0.44 0.00 0.27 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma ARL13B 0.03 0.00 blup 39 0.00 2.1e-01 -6.5 6.0 1.7e-09 0.66 0.01 0.68 FALSE
17 The Cancer Genome Atlas Thyroid Carcinoma STX19 0.24 0.03 enet 10 0.09 2.4e-09 5.9 5.4 8.0e-08 0.36 0.01 0.46 FALSE