[Hub]/) : Traits : Trunk fat-free mass : →

chr1:752,566-3,191,909

Best TWAS P=1.56e-11 · Best GWAS P=4.88e-10 conditioned to 0.223

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Brain Cerebellar Hemisphere	RP5-890O3.9	0.24	0.02	lasso	9	0.02	1.3e-01	-6.2	6.7	1.6e-11	-0.70	0.02	0.67	TRUE
20	METSIM	Adipose	TNFRSF14	0.07	0.05	blup	373	0.05	1.9e-07	3.3	6.1	1.0e-09	-0.05	0.98	0.00	TRUE
10	GTEx	Esophagus Muscularis	RP11-181G12.2	0.23	0.14	lasso	4	0.19	1.0e-11	5.1	6.0	2.1e-09	0.04	0.38	0.62	TRUE
5	GTEx	Adipose Visceral Omentum	RP11-345P4.6	0.40	0.24	enet	28	0.20	1.8e-10	2.6	5.6	2.5e-08	-0.13	1.00	0.00	TRUE
3	GTEx	Adipose Subcutaneous	C1orf86	0.15	0.05	enet	10	0.04	2.0e-04	-5.2	-6.6	4.0e-11	0.28	0.38	0.14	FALSE
13	GTEx	Muscle Skeletal	NADK	0.06	0.00	enet	9	0.00	1.3e-01	-5.6	-6.0	1.7e-09	0.73	0.10	0.69	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SLC35E2	0.35	0.15	enet	24	0.17	1.0e-20	-6.2	6.0	2.3e-09	-0.82	0.01	0.99	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	RP11-181G12.2	0.16	0.02	enet	18	0.01	1.1e-01	5.9	6.0	2.3e-09	0.06	0.05	0.58	FALSE
12	GTEx	Lung	AL590822.2	0.09	0.00	lasso	3	0.00	2.0e-01	5.6	6.0	2.5e-09	0.07	0.04	0.53	FALSE
19	GTEx	Skin Sun Exposed Lower leg	TMEM52	0.17	0.14	lasso	7	0.15	2.0e-12	5.8	5.8	4.8e-09	-0.68	0.09	0.91	FALSE
11	GTEx	Lung	NADK	0.07	0.03	lasso	3	0.02	8.5e-03	5.2	-5.8	5.8e-09	0.73	0.07	0.81	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM52	0.02	0.01	blup	37	0.02	6.6e-03	-5.5	5.8	7.1e-09	-0.65	0.01	0.77	FALSE
6	GTEx	Brain Cerebellar Hemisphere	NADK	0.18	0.11	lasso	7	0.09	3.1e-03	-5.6	-5.8	8.8e-09	0.85	0.04	0.49	FALSE
15	GTEx	Muscle Skeletal	TMEM52	0.11	0.08	lasso	6	0.10	7.2e-10	-5.7	5.7	1.5e-08	-0.77	0.28	0.72	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	C1orf222	0.11	0.14	enet	18	0.14	1.8e-17	-3.9	5.6	1.8e-08	-0.65	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	RER1	0.06	0.00	blup	359	0.01	8.1e-03	1.2	-5.6	1.9e-08	0.19	0.04	0.18	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	TMEM52	0.19	0.18	lasso	4	0.14	2.6e-08	5.2	5.6	2.1e-08	-0.67	0.08	0.92	FALSE
16	GTEx	Muscle Skeletal	RP11-181G12.2	0.12	0.13	enet	8	0.14	7.6e-14	-5.2	5.4	5.6e-08	0.04	0.81	0.19	FALSE
17	GTEx	Nerve Tibial	RP11-181G12.2	0.24	0.22	lasso	5	0.21	3.7e-15	-5.2	5.4	5.6e-08	0.01	0.81	0.19	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1orf86	0.03	0.02	blup	49	0.01	1.3e-02	5.9	5.4	5.7e-08	0.05	0.03	0.70	FALSE
9	GTEx	Esophagus Mucosa	TMEM52	0.17	0.18	lasso	2	0.20	2.9e-13	-5.4	5.4	7.2e-08	-0.69	0.64	0.36	FALSE
14	GTEx	Muscle Skeletal	C1orf86	0.20	0.16	lasso	4	0.15	8.0e-15	-5.2	-5.3	8.9e-08	-0.01	0.81	0.19	FALSE
4	GTEx	Adipose Subcutaneous	RP11-181G12.2	0.09	0.07	lasso	1	0.05	1.3e-04	-5.2	5.2	2.0e-07	0.01	0.61	0.20	FALSE