[Hub]/) : Traits : Trunk fat-free mass :

chr1:752,566-3,191,909

Best TWAS P=1.56e-11 · Best GWAS P=4.88e-10 conditioned to 0.223

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RER1 0.06 0.00 blup 359 0.01 8.1e-03 1.2 -5.6 1.9e-08 0.19 0.04 0.18 FALSE
2 CommonMind Brain Pre-frontal Cortex SLC35E2 0.35 0.15 enet 24 0.17 1.0e-20 -6.2 6.0 2.3e-09 -0.82 0.01 0.99 FALSE
3 GTEx Adipose Subcutaneous C1orf86 0.15 0.05 enet 10 0.04 2.0e-04 -5.2 -6.6 4.0e-11 0.28 0.38 0.14 FALSE
4 GTEx Adipose Subcutaneous RP11-181G12.2 0.09 0.07 lasso 1 0.05 1.3e-04 -5.2 5.2 2.0e-07 0.01 0.61 0.20 FALSE
5 GTEx Adipose Visceral Omentum RP11-345P4.6 0.40 0.24 enet 28 0.20 1.8e-10 2.6 5.6 2.5e-08 -0.13 1.00 0.00 TRUE
6 GTEx Brain Cerebellar Hemisphere NADK 0.18 0.11 lasso 7 0.09 3.1e-03 -5.6 -5.8 8.8e-09 0.85 0.04 0.49 FALSE
7 GTEx Brain Cerebellar Hemisphere RP5-890O3.9 0.24 0.02 lasso 9 0.02 1.3e-01 -6.2 6.7 1.6e-11 -0.70 0.02 0.67 TRUE
8 GTEx Esophagus Gastroesophageal Junction RP11-181G12.2 0.16 0.02 enet 18 0.01 1.1e-01 5.9 6.0 2.3e-09 0.06 0.05 0.58 FALSE
9 GTEx Esophagus Mucosa TMEM52 0.17 0.18 lasso 2 0.20 2.9e-13 -5.4 5.4 7.2e-08 -0.69 0.64 0.36 FALSE
10 GTEx Esophagus Muscularis RP11-181G12.2 0.23 0.14 lasso 4 0.19 1.0e-11 5.1 6.0 2.1e-09 0.04 0.38 0.62 TRUE
11 GTEx Lung NADK 0.07 0.03 lasso 3 0.02 8.5e-03 5.2 -5.8 5.8e-09 0.73 0.07 0.81 FALSE
12 GTEx Lung AL590822.2 0.09 0.00 lasso 3 0.00 2.0e-01 5.6 6.0 2.5e-09 0.07 0.04 0.53 FALSE
13 GTEx Muscle Skeletal NADK 0.06 0.00 enet 9 0.00 1.3e-01 -5.6 -6.0 1.7e-09 0.73 0.10 0.69 FALSE
14 GTEx Muscle Skeletal C1orf86 0.20 0.16 lasso 4 0.15 8.0e-15 -5.2 -5.3 8.9e-08 -0.01 0.81 0.19 FALSE
15 GTEx Muscle Skeletal TMEM52 0.11 0.08 lasso 6 0.10 7.2e-10 -5.7 5.7 1.5e-08 -0.77 0.28 0.72 FALSE
16 GTEx Muscle Skeletal RP11-181G12.2 0.12 0.13 enet 8 0.14 7.6e-14 -5.2 5.4 5.6e-08 0.04 0.81 0.19 FALSE
17 GTEx Nerve Tibial RP11-181G12.2 0.24 0.22 lasso 5 0.21 3.7e-15 -5.2 5.4 5.6e-08 0.01 0.81 0.19 FALSE
18 GTEx Skin Not Sun Exposed Suprapubic TMEM52 0.19 0.18 lasso 4 0.14 2.6e-08 5.2 5.6 2.1e-08 -0.67 0.08 0.92 FALSE
19 GTEx Skin Sun Exposed Lower leg TMEM52 0.17 0.14 lasso 7 0.15 2.0e-12 5.8 5.8 4.8e-09 -0.68 0.09 0.91 FALSE
20 METSIM Adipose TNFRSF14 0.07 0.05 blup 373 0.05 1.9e-07 3.3 6.1 1.0e-09 -0.05 0.98 0.00 TRUE
21 ROSMAP Brain Pre-frontal Cortex C1orf222 0.11 0.14 enet 18 0.14 1.8e-17 -3.9 5.6 1.8e-08 -0.65 1.00 0.00 FALSE
22 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM52 0.02 0.01 blup 37 0.02 6.6e-03 -5.5 5.8 7.1e-09 -0.65 0.01 0.77 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C1orf86 0.03 0.02 blup 49 0.01 1.3e-02 5.9 5.4 5.7e-08 0.05 0.03 0.70 FALSE