[Hub]/) : Traits : Trunk fat-free mass :

chr5:111,499,732-112,950,045

Best TWAS P=9.77e-12 · Best GWAS P=7.13e-12 conditioned to 0.00178

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SRP19 0.08 0.06 lasso 5 0.07 1.3e-08 5.3 -5.6 1.7e-08 0.63 0.56 0.44 FALSE
2 GTEx Adipose Subcutaneous REEP5 0.10 0.09 lasso 2 0.05 2.8e-05 5.1 5.3 1.1e-07 -0.64 0.24 0.74 FALSE
3 GTEx Adipose Visceral Omentum REEP5 0.09 0.05 lasso 5 0.02 4.9e-02 5.9 5.8 7.4e-09 -0.60 0.04 0.90 FALSE
4 GTEx Artery Aorta REEP5 0.17 0.07 lasso 13 0.10 4.2e-06 6.4 6.0 1.8e-09 -0.74 0.02 0.98 FALSE
5 GTEx Artery Tibial REEP5 0.17 0.12 lasso 5 0.13 3.0e-10 5.1 5.3 1.0e-07 -0.58 0.41 0.59 FALSE
6 GTEx Cells Transformed fibroblasts CTC-487M23.5 0.07 0.03 lasso 3 0.03 2.9e-03 -4.5 -5.6 2.4e-08 0.66 0.04 0.89 FALSE
7 GTEx Colon Transverse REEP5 0.12 0.14 lasso 2 0.14 4.4e-07 5.7 5.8 5.4e-09 -0.58 0.13 0.86 FALSE
8 GTEx Esophagus Gastroesophageal Junction REEP5 0.18 0.03 lasso 3 0.03 3.7e-02 6.1 6.0 2.1e-09 -0.61 0.03 0.88 FALSE
9 GTEx Esophagus Mucosa REEP5 0.19 0.10 lasso 5 0.09 1.5e-06 6.1 6.1 1.0e-09 -0.60 0.04 0.94 FALSE
10 GTEx Esophagus Muscularis REEP5 0.18 0.09 lasso 4 0.14 5.9e-09 5.7 5.5 3.9e-08 -0.68 0.28 0.72 FALSE
11 GTEx Nerve Tibial REEP5 0.16 0.13 lasso 3 0.10 9.2e-08 5.1 5.3 1.2e-07 -0.59 0.83 0.16 FALSE
12 GTEx Nerve Tibial XBP1P1 0.06 0.05 lasso 2 0.04 6.1e-04 4.7 5.2 2.5e-07 -0.78 0.40 0.29 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic REEP5 0.11 0.10 lasso 7 0.10 6.3e-06 5.1 5.6 1.9e-08 -0.63 0.13 0.86 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic CTC-487M23.5 0.10 0.06 lasso 3 0.05 6.7e-04 5.5 5.5 4.7e-08 -0.56 0.18 0.51 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic CTC-487M23.7 0.08 0.09 enet 7 0.10 3.9e-06 5.5 5.9 4.4e-09 -0.65 0.12 0.84 FALSE
16 GTEx Skin Sun Exposed Lower leg REEP5 0.08 0.05 lasso 4 0.03 1.9e-03 5.1 5.3 1.4e-07 -0.70 0.17 0.81 FALSE
17 GTEx Skin Sun Exposed Lower leg CTC-487M23.5 0.17 0.07 lasso 6 0.06 7.7e-06 5.6 5.8 8.9e-09 -0.60 0.30 0.70 FALSE
18 GTEx Skin Sun Exposed Lower leg CTC-487M23.7 0.06 0.07 lasso 1 0.04 2.4e-04 5.6 5.6 1.8e-08 -0.52 0.06 0.92 FALSE
19 GTEx Testis REEP5 0.22 0.14 lasso 5 0.14 6.6e-07 5.7 6.2 7.4e-10 -0.59 0.07 0.92 FALSE
20 NTR Blood REEP5 0.03 0.04 lasso 9 0.04 3.3e-12 6.4 6.8 9.8e-12 -0.66 0.02 0.98 TRUE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma APC 0.03 0.02 blup 77 0.02 5.2e-03 5.8 5.5 2.9e-08 -0.45 0.02 0.49 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma SRP19 0.05 0.04 lasso 3 0.04 3.7e-05 5.5 -5.6 1.9e-08 0.60 0.60 0.34 FALSE
23 The Cancer Genome Atlas Stomach Adenocarcinoma REEP5 0.03 0.02 blup 47 0.03 4.1e-03 5.5 5.7 1.1e-08 -0.67 0.04 0.37 FALSE
24 The Cancer Genome Atlas Thyroid Carcinoma APC 0.02 0.02 enet 5 0.02 4.2e-03 -5.2 5.2 1.9e-07 -0.74 0.08 0.63 FALSE