[Hub]/) : Traits : Trunk fat-free mass :

chr7:75,913,086-77,744,459

Best TWAS P=7.79e-15 · Best GWAS P=7.28e-12 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DTX2P1-UPK3BP1-PMS2P11 0.18 0.09 enet 21 0.12 6.1e-15 6.1 7.8 7.8e-15 0.82 0.00 1.00 TRUE
2 GTEx Adipose Subcutaneous RP11-467H10.2 0.12 0.00 lasso 6 0.01 2.1e-02 3.1 6.0 1.4e-09 0.05 0.13 0.04 FALSE
3 GTEx Artery Aorta GSAP 0.19 0.07 lasso 2 0.04 2.8e-03 5.6 -5.9 3.2e-09 -0.03 0.25 0.09 TRUE
4 GTEx Brain Cerebellum GSAP 0.38 0.30 lasso 4 0.31 6.4e-10 5.4 -5.6 1.9e-08 -0.01 0.77 0.18 FALSE
5 GTEx Brain Frontal Cortex BA9 GSAP 0.38 0.22 lasso 6 0.21 3.0e-06 5.5 -6.4 1.3e-10 -0.13 0.14 0.22 TRUE
6 GTEx Heart Left Ventricle GSAP 0.21 0.02 lasso 5 0.03 9.3e-03 4.8 -5.6 1.8e-08 -0.01 0.12 0.05 TRUE
7 GTEx Muscle Skeletal GSAP 0.20 0.12 lasso 2 0.12 1.8e-11 5.5 -5.6 1.8e-08 -0.04 0.80 0.20 FALSE
8 GTEx Skin Sun Exposed Lower leg DTX2P1 0.16 0.03 enet 22 0.05 4.8e-05 6.9 5.4 5.5e-08 0.70 0.00 0.99 FALSE
9 GTEx Thyroid GSAP 0.19 0.08 lasso 3 0.07 3.3e-06 5.6 -5.7 9.8e-09 -0.02 0.69 0.23 FALSE
10 GTEx Thyroid AC007000.12 0.13 0.08 enet 24 0.07 2.6e-06 -4.5 -5.5 3.1e-08 -0.18 0.66 0.02 TRUE
11 ROSMAP Brain Pre-frontal Cortex GSAP 0.36 0.27 lasso 7 0.28 1.5e-35 5.5 -5.4 6.6e-08 -0.02 0.80 0.20 TRUE
12 The Cancer Genome Atlas Brain Lower Grade Glioma PION 0.08 0.05 lasso 3 0.05 8.5e-07 5.6 -5.7 1.5e-08 -0.06 0.00 1.00 TRUE
13 The Cancer Genome Atlas Prostate Adenocarcinoma PION 0.13 0.07 enet 9 0.08 3.4e-09 5.6 -5.5 4.8e-08 -0.03 0.00 1.00 FALSE