[Hub]/) : Traits : Trunk fat-free mass : ← →

chr7:90,624,416-93,160,671

Best TWAS P=4.64e-72 · Best GWAS P=2.09e-65 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
33	GTEx	Testis	CDK6	0.10	0.10	lasso	3	0.09	8.0e-05	17.03	-18.0	4.6e-72	-0.92	0.02	0.97	TRUE
16	GTEx	Colon Transverse	GATAD1	0.13	0.00	enet	16	0.05	3.0e-03	8.57	-9.7	5.0e-22	-0.38	0.21	0.14	TRUE
13	GTEx	Brain Cortex	AC000120.7	0.12	0.08	enet	16	0.07	7.0e-03	4.84	-6.7	1.8e-11	-0.42	0.14	0.05	TRUE
2	CommonMind	Brain Pre-frontal Cortex	KRIT1	0.04	0.01	blup	318	0.02	1.2e-03	4.92	-6.2	5.5e-10	-0.23	0.60	0.02	TRUE
10	GTEx	Artery Tibial	AC000120.7	0.08	0.06	lasso	4	0.06	3.2e-05	4.71	-6.0	1.9e-09	-0.26	0.96	0.00	TRUE
38	ROSMAP	Brain Pre-frontal Cortex	MTERF	0.04	0.00	blup	375	0.02	7.5e-04	2.17	5.6	2.0e-08	0.21	0.09	0.30	TRUE
42	The Cancer Genome Atlas	Breast Invasive Carcinoma	CYP51A1	0.01	0.02	blup	51	0.02	2.0e-04	5.00	-5.1	2.9e-07	-0.23	0.04	0.93	TRUE
1	CommonMind	Brain Pre-frontal Cortex	CDK6	0.12	0.10	lasso	2	0.10	1.9e-12	16.88	16.9	5.3e-64	1.00	0.01	0.99	FALSE
19	GTEx	Esophagus Muscularis	FAM133B	0.07	0.01	enet	2	0.01	1.2e-01	-11.62	-11.7	1.7e-31	-0.46	0.06	0.44	FALSE
15	GTEx	Cells Transformed fibroblasts	GATAD1	0.23	0.20	lasso	4	0.22	1.4e-16	8.57	-11.3	9.3e-30	-0.58	0.98	0.02	FALSE
41	YFS	Blood	GATAD1	0.01	0.01	blup	297	0.01	5.1e-04	8.57	-11.2	6.8e-29	-0.55	0.73	0.10	FALSE
12	GTEx	Brain Caudate basal ganglia	GATAD1	0.21	0.09	lasso	4	0.08	2.3e-03	6.72	-9.8	1.3e-22	-0.43	0.08	0.24	FALSE
5	GTEx	Adrenal Gland	GATAD1	0.40	0.22	lasso	7	0.25	2.0e-09	8.57	-9.7	2.1e-22	-0.47	0.68	0.07	FALSE
28	GTEx	Skin Sun Exposed Lower leg	PEX1	0.18	0.06	enet	41	0.03	1.5e-03	-9.27	-9.5	2.0e-21	-0.39	0.20	0.18	FALSE
17	GTEx	Esophagus Mucosa	GATAD1	0.16	0.05	enet	16	0.08	7.3e-06	8.57	-9.1	7.1e-20	-0.42	0.81	0.06	FALSE
37	ROSMAP	Brain Pre-frontal Cortex	KRIT1	0.04	0.03	bslmm	311	0.01	9.0e-03	4.98	8.9	4.3e-19	0.49	0.75	0.05	FALSE
32	GTEx	Stomach	GATAD1	0.30	0.13	lasso	5	0.15	8.6e-08	8.57	-8.8	8.9e-19	-0.46	0.98	0.00	FALSE
8	GTEx	Artery Coronary	GATAD1	0.12	0.15	lasso	3	0.12	8.0e-05	8.44	-8.8	1.1e-18	-0.41	0.19	0.20	FALSE
27	GTEx	Skin Not Sun Exposed Suprapubic	GATAD1	0.22	0.27	lasso	4	0.26	1.1e-14	8.57	-8.7	2.3e-18	-0.42	1.00	0.00	FALSE
39	ROSMAP	Brain Pre-frontal Cortex	GATAD1	0.17	0.15	lasso	4	0.16	6.0e-20	8.45	-8.7	2.8e-18	-0.43	1.00	0.00	FALSE
7	GTEx	Artery Aorta	GATAD1	0.09	0.08	enet	4	0.07	7.4e-05	8.57	-8.7	3.0e-18	-0.42	0.53	0.04	FALSE
30	GTEx	Spleen	PEX1	0.18	0.00	enet	38	0.05	2.4e-02	4.97	-8.7	3.0e-18	-0.32	0.08	0.07	FALSE
4	GTEx	Adipose Visceral Omentum	GATAD1	0.12	0.08	lasso	5	0.06	7.5e-04	8.57	-8.7	4.0e-18	-0.46	0.82	0.06	FALSE
20	GTEx	Lung	GATAD1	0.15	0.12	lasso	2	0.11	1.1e-08	8.57	-8.6	1.2e-17	-0.42	0.99	0.00	FALSE
29	GTEx	Skin Sun Exposed Lower leg	GATAD1	0.30	0.10	enet	14	0.16	7.0e-13	8.57	-8.4	3.6e-17	-0.39	1.00	0.00	FALSE
23	GTEx	Muscle Skeletal	GATAD1	0.05	0.00	enet	13	0.01	2.4e-02	3.75	-8.4	3.8e-17	-0.38	0.48	0.03	FALSE
34	GTEx	Thyroid	GATAD1	0.18	0.06	lasso	4	0.06	3.3e-05	8.57	-8.4	4.9e-17	-0.43	0.94	0.03	FALSE
14	GTEx	Breast Mammary Tissue (Female)	AC007566.10	0.04	-0.01	lasso	2	0.01	2.0e-01	1.57	-8.4	6.0e-17	-0.37	0.02	0.23	FALSE
9	GTEx	Artery Tibial	GATAD1	0.14	0.04	enet	17	0.04	4.1e-04	8.57	-8.3	1.5e-16	-0.38	0.70	0.10	FALSE
45	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GATAD1	0.04	0.04	lasso	2	0.03	2.8e-04	8.21	-7.9	2.5e-15	-0.36	0.15	0.11	FALSE
25	GTEx	Pancreas	GATAD1	0.12	0.13	lasso	2	0.14	2.0e-06	8.57	-7.8	8.2e-15	-0.40	0.18	0.45	FALSE
6	GTEx	Artery Aorta	KRIT1	0.15	0.00	enet	24	0.03	1.3e-02	0.64	-7.7	1.4e-14	-0.28	0.12	0.05	FALSE
43	The Cancer Genome Atlas	Breast Invasive Carcinoma	GATAD1	0.06	0.04	lasso	6	0.04	2.2e-09	8.21	-7.5	5.3e-14	-0.31	0.89	0.10	FALSE
22	GTEx	Muscle Skeletal	PEX1	0.06	0.03	lasso	5	0.02	2.7e-03	6.90	7.5	6.0e-14	0.30	0.54	0.13	FALSE
18	GTEx	Esophagus Muscularis	GATAD1	0.18	0.10	enet	33	0.13	1.6e-08	8.57	-7.2	8.4e-13	-0.32	0.98	0.00	FALSE
11	GTEx	Artery Tibial	AC007566.10	0.13	0.04	lasso	5	0.00	3.1e-01	5.89	-7.0	2.1e-12	-0.15	0.08	0.04	FALSE
40	YFS	Blood	CYP51A1	0.03	0.06	blup	288	0.05	1.2e-16	4.94	-6.6	3.6e-11	-0.31	1.00	0.00	FALSE
35	METSIM	Adipose	GATAD1	0.10	0.05	lasso	7	0.06	9.4e-10	3.75	-6.6	4.3e-11	-0.40	1.00	0.00	FALSE
24	GTEx	Nerve Tibial	GATAD1	0.30	0.19	lasso	5	0.23	1.8e-16	8.57	-6.6	5.0e-11	-0.35	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	GATAD1	0.21	0.14	enet	10	0.16	3.4e-13	8.57	-6.4	1.9e-10	-0.37	1.00	0.00	FALSE
47	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C7orf64	0.06	0.02	blup	36	0.02	6.0e-02	7.08	6.2	7.3e-10	0.22	0.04	0.05	FALSE
26	GTEx	Pituitary	KRIT1	0.21	-0.01	enet	14	0.20	1.1e-05	0.40	-5.8	5.1e-09	-0.09	0.28	0.07	FALSE
21	GTEx	Muscle Skeletal	CYP51A1	0.10	0.18	enet	21	0.17	5.0e-16	4.92	-5.6	2.5e-08	-0.24	1.00	0.00	FALSE
31	GTEx	Spleen	AC000120.7	0.10	0.07	lasso	5	0.04	3.9e-02	5.08	-5.3	1.4e-07	-0.23	0.15	0.08	FALSE
36	ROSMAP	Brain Pre-frontal Cortex	ANKIB1	0.03	0.03	enet	8	0.03	2.6e-04	5.01	-5.2	1.6e-07	-0.28	0.70	0.01	FALSE
44	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CYP51A1	0.07	0.04	lasso	2	0.04	4.3e-05	5.01	-5.2	1.8e-07	-0.27	0.04	0.95	FALSE
46	The Cancer Genome Atlas	Lung Adenocarcinoma	CYP51A1	0.03	0.03	enet	12	0.03	1.2e-04	5.00	-5.1	2.8e-07	-0.27	0.04	0.90	FALSE