TWAS hub - PION

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0432	0.0121	1.1e-10	0.035	0.038	0.041	0.031	0.027	2.4e-11	3.2e-12	2.7e-13	2.3e-10	2.6e-09
2	TCGA	Breast Invasive Carcinoma	0.0529	0.0203	1.2e-05	0.014	0.022	0.030	NA	0.031	5.3e-04	1.8e-05	6.8e-07	NA	4.4e-07
3	TCGA	Kidney Renal Clear Cell Carcinoma	0.1292	0.0355	6.3e-09	0.058	0.072	0.088	NA	0.090	4.4e-07	1.8e-08	4.3e-10	NA	2.7e-10
4	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0800	0.0370	3.6e-03	-0.001	0.025	-0.001	NA	0.000	3.6e-01	1.3e-02	3.8e-01	NA	3.3e-01
5	TCGA	Brain Lower Grade Glioma	0.0845	0.0339	1.7e-04	0.048	0.037	0.054	NA	0.054	3.2e-06	3.9e-05	9.2e-07	NA	8.5e-07
6	TCGA	Liver Hepatocellular Carcinoma	0.3080	0.0870	7.0e-07	0.110	0.148	0.114	NA	0.137	7.8e-06	1.9e-07	5.2e-06	NA	5.3e-07
7	TCGA	Lung Adenocarcinoma	0.0487	0.0264	5.3e-03	-0.002	0.011	0.015	NA	0.002	8.2e-01	1.5e-02	6.3e-03	NA	1.5e-01
8	TCGA	Prostate Adenocarcinoma	0.1297	0.0437	5.7e-06	0.071	0.054	0.085	NA	0.072	6.9e-08	2.2e-06	3.5e-09	NA	5.5e-08
9	TCGA	Thyroid Carcinoma	0.1860	0.0540	3.9e-07	0.022	0.089	0.085	NA	0.077	2.7e-03	5.2e-09	1.1e-08	NA	6.3e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Ever highly irritable/argumentative for 2 days	5.3	6.3	12.6	1.1	3.5	2.9	1.1	3.0	0.3	2.3	3.5	2.7
Arm predicted mass (right)	3.0	15.1	43.4	0.9	-3.2	-3.2	-2.7	-6.6	1.5	-3.6	-6.4	-2.8
BMI	2.8	16.4	35.3	3.2	-3.1	-3.1	-3.6	-5.9	2.5	-4.0	-5.7	-3.8
Arm fat mass (right)	2.8	11.5	26.2	2.5	-2.4	-2.9	-3.0	-5.1	1.4	-3.4	-5.0	-2.9
Arm fat-free mass (right)	2.8	14.3	41.3	1.1	-3.1	-3.0	-2.6	-6.4	1.7	-3.3	-6.2	-2.7
Prostate Cancer	2.7	3.8	12.8	0.6	-2.6	-3.6	-0.3	-1.2	0.8	-1.1	-2.2	-2.4
Arm fat mass (left)	2.7	11.2	26.2	2.3	-2.3	-2.8	-3.0	-5.1	1.1	-3.3	-5.1	-3.0
Weight	2.6	12.7	31.5	1.8	-2.7	-3.1	-3.0	-5.6	1.0	-3.6	-5.5	-3.0
Whole body fat mass	2.6	10.7	25.2	2.1	-2.4	-3.0	-2.8	-5.0	1.2	-3.1	-5.0	-3.0
Commuting to job workplace: Walk	2.6	2.8	6.8	0.9	-2.2	-2.1	-1.7	0.3	1.5	-1.7	-0.6	-2.6
Type 2 Diabetes (T2D) (2012)	2.5	2.9	7.6	0.9	-2.1	-0.5	-1.0	-2.6	1.1	-1.6	-2.8	-1.4
Body mass index (BMI)	2.5	10.5	23.9	3.0	-2.1	-2.2	-2.7	-4.9	1.6	-3.4	-4.7	-2.8
Leg fat mass (right)	2.5	9.7	23.1	2.5	-2.1	-2.6	-2.4	-4.7	1.6	-2.9	-4.8	-2.7
Arm fat-free mass (left)	2.5	12.6	37.9	1.4	-2.5	-2.7	-2.7	-6.2	1.5	-3.2	-5.9	-2.4
Age started oral contraceptive pill	2.5	3.1	5.0	1.3	-2.2	-2.2	-2.1	-1.1	0.7	-1.9	-1.3	-2.1
Leg fat mass (left)	2.5	9.6	23.2	2.5	-2.1	-2.5	-2.4	-4.8	1.5	-2.8	-4.8	-2.7
Illnesses of siblings: Diabetes	2.3	2.8	5.9	0.4	-1.9	-1.7	-1.0	-1.8	1.4	-1.8	-2.4	-1.8
Basal metabolic rate	2.3	12.7	34.9	1.3	-2.6	-3.0	-2.8	-5.9	1.5	-3.5	-5.7	-2.6
Arm predicted mass (left)	2.3	11.9	36.4	1.0	-2.5	-2.7	-2.4	-6.0	1.3	-3.1	-5.8	-2.3
Age when periods started (menarche)	2.2	5.3	9.8	1.4	-2.2	-2.4	-2.6	-2.5	-0.8	-2.5	-2.4	-3.1
Stomach or abdominal pain in last month	2.2	2.8	7.6	2.8	2.2	1.6	0.8	2.3	0.5	-0.2	1.8	0.8
Trunk fat mass	2.2	9.3	22.4	1.6	-2.1	-2.9	-2.8	-4.7	0.8	-2.8	-4.7	-2.8
High blood pressure (siblings)	2.2	3.2	7.6	-0.1	-1.5	-2.2	-1.9	-0.8	1.2	-2.3	-1.7	-2.8
Whole body water mass	2.2	12.4	33.8	1.2	-2.7	-2.9	-2.7	-5.8	1.8	-3.4	-5.6	-2.5
Waist circumference	2.1	7.8	19.4	2.3	-2.0	-1.9	-1.9	-4.4	1.4	-2.8	-4.4	-2.4
Whole body fat-free mass	2.1	12.3	34.2	1.0	-2.7	-3.0	-2.8	-5.8	1.7	-3.3	-5.6	-2.5
Leg fat-free mass (left)	2.0	10.6	26.7	1.3	-2.3	-2.8	-2.7	-5.2	2.3	-3.1	-5.1	-2.4
High blood pressure (mother)	2.0	2.8	5.4	1.6	-1.2	-2.3	-2.0	-0.4	2.1	-1.4	-1.1	-2.2
Leg predicted mass (left)	2.0	10.5	27.5	1.2	-2.3	-2.8	-2.6	-5.2	2.3	-3.1	-5.1	-2.3
Trunk fat-free mass	2.0	11.5	32.0	1.0	-2.7	-2.8	-2.6	-5.7	1.4	-3.2	-5.5	-2.4
Trunk predicted mass	2.0	11.5	32.0	1.0	-2.7	-2.8	-2.7	-5.7	1.4	-3.2	-5.5	-2.4
Arm fat percentage (left)	2.0	7.9	14.6	2.8	-1.8	-2.4	-2.8	-3.7	0.9	-2.9	-3.8	-2.9
Bipolar Disorder (2011)	1.9	1.9	5.2	-0.6	1.2	0.8	1.4	1.7	-0.4	2.3	1.6	1.3
Allergy or Eczema	1.9	5.1	20.8	4.6	1.5	0.4	-0.3	2.8	-0.2	-3.3	1.1	-1.5
Arm fat percentage (right)	1.9	7.4	13.0	3.0	-1.6	-2.4	-2.7	-3.5	1.0	-2.9	-3.6	-2.7
Length of working week for main job	1.9	2.1	5.7	0.4	0.4	0.7	1.7	2.1	1.0	1.6	2.4	1.0
Average weekly beer plus cider intake	1.9	2.8	6.1	-0.1	2.5	2.2	0.9	2.2	-0.2	1.6	1.8	1.5
Nervous feelings	1.8	3.3	9.6	1.5	-0.8	-2.1	-2.1	-0.4	-0.4	-2.6	-1.1	-3.1
Allergy	1.8	4.1	8.8	-2.8	-2.4	-0.8	-0.1	-3.0	2.5	2.3	-1.6	0.7
Hip circumference	1.8	7.6	20.5	0.7	-2.1	-2.5	-2.4	-4.5	-0.0	-2.6	-4.4	-2.2
Blood clot in the leg (DVT)	1.8	2.3	7.8	-2.0	1.4	1.4	1.3	0.2	-2.8	1.0	0.6	1.3
Medication: Amlodipine	1.8	2.5	6.5	0.1	-1.3	-0.9	-1.3	-2.2	1.6	-1.8	-2.5	-0.9
Leg fat-free mass (right)	1.8	9.8	24.3	1.1	-2.5	-2.8	-2.6	-4.9	2.2	-3.0	-4.8	-2.3
Leg predicted mass (right)	1.8	9.8	25.0	1.0	-2.5	-2.7	-2.7	-5.0	2.2	-3.0	-4.8	-2.2
Hayfever, allergic rhinitis or eczema	1.7	3.7	10.6	3.3	2.4	0.9	0.3	3.0	-0.7	-1.8	1.7	-0.5
Hearing aid user	1.7	1.9	5.0	0.5	-1.9	-2.1	-1.1	-0.5	-0.6	-1.4	-0.8	-2.2
Deep venous thrombosis (DVT) (self-reported)	1.7	2.2	8.3	-2.2	1.0	1.1	1.1	0.5	-2.9	1.0	0.7	1.1
Impedance of arm (right)	1.6	7.4	24.4	-0.9	2.3	1.3	1.1	4.9	-2.5	2.1	4.6	1.4
Body fat percentage	1.6	6.2	13.6	2.0	-1.5	-2.4	-2.3	-3.5	0.4	-2.4	-3.7	-2.6
Qualifications: NVQ or HND or HNC or equivalent	1.6	2.0	4.2	0.4	-0.6	-0.9	-1.5	-1.8	-1.0	-2.1	-1.9	-1.4
Body Mass Index (BMI) (2010)	1.5	2.0	5.7	0.7	-0.6	-0.6	-1.3	-2.4	0.6	-1.6	-2.2	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.3	8.8	-0.6	3.0	1.1	1.4	1.9	-1.6	0.5	1.1	0.7
Leg pain on walking	1.5	1.8	7.5	2.7	1.1	0.2	-0.6	0.7	-1.8	-1.4	0.4	-1.2
Diabetes diagnosed by doctor	1.5	2.4	4.8	2.0	-1.5	-1.3	-0.7	-1.8	2.2	-1.1	-1.6	-1.1
Alcohol drinker status: Previous	1.5	1.7	5.2	2.3	0.9	1.0	-1.4	0.3	2.1	-1.0	0.4	-0.5
Impedance of whole body	1.5	7.8	21.5	-1.7	2.0	1.3	1.4	4.6	-3.5	2.5	4.3	1.3
Impedance of leg (right)	1.4	6.7	13.3	-1.3	2.3	1.8	2.0	3.7	-3.6	2.4	3.4	1.8
Trunk fat percentage	1.4	5.7	12.6	1.4	-1.5	-2.4	-2.4	-3.4	0.1	-2.2	-3.5	-2.4
Impedance of leg (left)	1.4	7.0	14.3	-1.4	2.1	1.8	1.9	3.6	-3.8	2.6	3.5	1.8
Heart attack	1.4	1.8	5.3	1.2	-0.3	-1.6	-1.4	-0.2	0.7	-1.7	-1.0	-2.3
Impedance of arm (left)	1.4	6.6	21.3	-1.5	1.8	1.1	0.9	4.6	-2.8	1.9	4.2	1.1
Peak expiratory flow (PEF)	1.4	3.2	8.5	-0.4	-0.3	-1.5	-1.4	-2.9	-1.9	-1.2	-2.9	-1.7
Loud music exposure frequency	1.4	1.6	3.8	0.9	0.8	1.1	0.9	1.2	-1.1	1.2	1.9	1.7
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	3.8	0.0	1.9	1.5	1.6	1.2	-1.8	0.6	1.2	1.1
Commuting to job workplace: Cycle	1.4	1.7	5.7	-0.7	-0.1	0.2	1.7	1.1	2.4	1.5	0.6	1.5
Heart attack/myocardial infarction (self-reported)	1.4	1.8	5.4	1.0	-0.4	-1.8	-1.5	-0.1	0.5	-1.6	-0.9	-2.3
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	3.5	1.9	1.1	0.4	0.5	1.9	1.7	-0.1	1.5	0.9
Illnesses of siblings	1.3	1.9	3.8	1.1	1.7	1.6	1.1	0.7	-0.8	1.4	1.5	2.0
Breastfed as a baby	1.3	1.6	3.8	-1.0	-1.7	-1.4	-0.3	-1.9	0.4	0.1	-1.9	-1.1
Leg fat percentage (right)	1.3	4.7	11.6	2.4	-1.0	-1.5	-1.6	-3.3	0.3	-2.1	-3.4	-1.9
Illnesses of father: High blood pressure	1.3	1.6	8.9	1.6	0.4	-0.3	-3.0	-0.2	0.5	-1.2	-0.2	-0.9
Leg fat percentage (left)	1.3	4.8	11.3	2.6	-1.2	-1.5	-1.7	-3.3	0.2	-2.1	-3.4	-1.9
Vascular/heart problems diagnosed by doctor	1.3	3.5	6.8	-1.8	0.7	1.5	2.3	1.9	-1.1	2.6	2.3	1.9
Crohns Disease (2017)	1.2	2.6	4.4	1.6	1.6	2.1	1.2	2.0	0.9	0.9	1.9	1.6
Depression (self-reported)	1.2	1.4	3.2	-0.7	1.5	0.9	0.7	1.8	-1.1	0.7	1.7	1.0
Chronic bronchitis/emphysema (mother)	1.2	1.4	3.9	-1.2	0.2	1.3	2.0	0.3	-0.2	1.8	0.6	1.4
Illness, injury, bereavement, stress in last 2 years	1.2	1.4	3.5	-0.9	-1.9	-1.2	-1.4	-1.2	0.2	-0.1	-0.8	-1.7
Neuroticism (2016)	1.1	1.5	5.0	0.9	0.7	-0.4	-2.2	0.7	-1.0	-1.6	0.4	-1.8
Average weekly spirits intake	1.1	1.3	3.9	-0.9	-1.1	-2.0	-1.9	-0.7	-0.1	-0.6	-0.6	-1.2
Medication: Simvastatin	1.1	1.6	5.5	1.3	0.7	-0.8	-2.3	-1.0	-0.7	-1.2	-0.6	-1.5
Medication: Lansoprazole	1.1	1.3	3.8	1.1	0.4	0.8	-0.7	1.9	0.8	0.4	1.9	0.9
Tense / ‘highly strung’	1.1	1.8	6.0	1.3	2.4	0.3	-1.0	2.1	-0.2	-0.7	1.5	0.2
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.1	4.6	-0.3	-1.5	-0.9	-0.5	-2.1	-0.2	-0.1	-1.3	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	3.0	0.8	1.1	1.0	-1.7	-1.0	1.5	-1.3	-0.8	0.2
Alzheimer’s Disease (in father)	1.0	1.1	2.4	1.6	-1.0	-1.2	-0.0	-0.7	-0.5	-0.9	-1.0	-1.4
Diabetes (mother)	1.0	1.3	4.9	0.3	0.3	-0.5	-0.8	-1.8	-0.4	-1.2	-2.2	-0.9
Supplements: Glucosamine	1.0	1.3	5.3	-2.3	-0.7	0.1	0.9	-1.3	-1.5	0.6	-1.0	0.4
Medication: Ramipril	1.0	1.3	3.0	1.4	0.8	-0.5	-1.7	1.2	0.2	-1.4	0.4	-1.6
Alcohol intake versus 10 years previously	1.0	1.5	5.6	2.4	-0.4	-0.6	-1.1	0.1	0.1	-1.8	0.0	-1.6
Noisy workplace	1.0	1.3	3.7	0.2	1.9	1.5	0.6	1.1	-1.2	0.4	1.3	0.6
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	3.0	-1.2	0.8	1.0	1.6	0.1	-0.5	1.2	0.5	1.7
Pulse wave reflection index	1.0	1.3	3.2	0.6	1.5	1.7	0.6	1.8	-0.3	0.6	1.4	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.1	3.9	1.4	-0.4	-0.8	-0.6	-0.5	-0.8	-2.0	-1.2	-0.7
Ever had prostate specific antigen (PSA) test	1.0	1.1	3.1	-1.5	0.5	0.9	1.8	0.1	-0.8	1.4	0.1	1.2
Ever depressed for a whole week	1.0	1.2	3.4	1.9	1.1	1.1	0.3	1.3	1.0	0.3	1.3	0.7
Coronary Artery Disease (CAD)	0.9	1.1	2.4	0.6	-1.6	-0.9	-0.8	-0.9	1.0	-1.1	-1.1	-1.1
Fasting Glucose	0.9	1.0	3.3	1.8	-0.8	-1.4	-0.8	-0.1	-0.3	-1.0	0.0	-1.4
Respiratory disease	0.9	1.9	4.6	1.5	1.4	0.8	-0.7	2.1	-2.2	-0.3	1.7	-0.1
Number of treatments/medications taken	0.9	1.7	4.3	1.7	-0.9	-1.5	-0.9	-0.3	1.0	-2.1	-1.1	-1.5
Hearing difficulty/problems: Yes	0.9	1.3	3.9	-0.0	-2.0	-1.2	-0.2	-1.5	-0.9	-0.8	-1.1	-1.2
Prospective memory result	0.9	1.1	4.0	0.6	2.0	1.3	0.3	1.2	-0.3	-0.6	0.9	1.1
Medication: Allopurinol	0.9	1.2	3.9	-2.0	-0.8	-0.8	-1.1	-1.0	1.2	0.2	-1.1	0.4
Medication: Omeprazole	0.9	1.0	2.6	-1.2	-1.0	-1.6	-0.6	-1.0	-0.3	-0.9	-1.4	-0.1
Medication: Seretide 50 evohaler	0.9	1.0	2.3	1.1	0.7	0.9	-1.5	0.9	1.1	-1.4	0.4	0.4
Number of full sisters	0.9	1.0	2.0	0.6	1.0	1.3	1.4	0.5	1.0	1.1	0.9	1.1
Knee pain experienced in last month	0.9	1.4	5.7	-0.3	-0.5	-0.5	-1.4	-2.4	0.7	-0.2	-1.8	-0.4
Hypertension (Self-reported)	0.9	2.4	5.3	1.0	-0.7	-1.4	-1.6	-2.0	1.1	-1.5	-2.3	-1.5
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	3.8	2.0	-0.1	-0.8	-1.4	1.3	1.1	-1.1	0.8	-1.4
Back pain experienced in last month	0.9	1.3	5.8	2.4	0.2	0.0	-1.2	0.1	1.5	-1.5	-0.1	0.1
Osteoporosis (self-reported)	0.9	1.1	3.3	-1.2	-0.2	0.2	-0.3	0.7	1.8	1.4	0.6	1.5
Medication: Bendroflumethiazide	0.9	1.4	4.0	1.0	-0.3	-0.7	-1.1	-1.7	1.4	-0.8	-2.0	-0.3
Unable to work because of sickness or disability	0.9	1.1	3.6	0.7	-1.2	-0.7	-0.9	-0.8	-0.4	-1.9	-0.7	-1.5
Medication: Omeprazole (e.g. Zanprol)	0.9	1.2	3.2	-0.9	-1.0	-1.8	-0.9	-0.8	-0.6	-1.2	-1.4	-0.5
Supplements: Calcium	0.9	1.0	3.6	-0.7	-1.4	-1.2	-1.9	-0.5	1.1	0.1	-0.2	-0.3
Alzheimer’s Disease (in mother)	0.8	1.0	3.3	-1.8	0.7	-0.3	0.6	1.3	-1.0	0.5	1.1	0.4
Irritable Bowel Disease (IBD)	0.8	1.9	2.6	1.5	1.4	1.2	1.6	1.5	1.2	1.2	1.1	1.6
Crohns Disease (2012)	0.8	1.3	2.7	0.7	1.5	1.6	0.6	0.9	1.1	1.1	0.8	1.5
Lupus	0.8	1.2	2.9	-1.5	0.7	0.9	1.3	0.1	1.3	0.8	-0.3	1.7
Type 2 Diabetes (T2D) (2018)	0.8	1.6	5.4	2.3	0.2	0.3	-0.6	-1.1	2.1	-1.2	-1.2	-0.2
Ever used hormone-replacement therapy (HRT)	0.8	1.0	2.8	0.3	-1.7	-1.6	0.5	0.2	0.7	-0.7	-0.5	-1.4
Medication: Metformin	0.8	1.2	5.2	2.3	0.0	-0.1	-0.6	-0.8	2.0	-0.0	-0.3	-0.0
Townsend deprivation index at recruitment	0.8	1.1	2.0	0.3	1.2	1.4	-0.3	1.1	1.4	0.3	1.4	1.0
High blood pressure	0.8	2.2	5.2	0.9	-0.6	-1.4	-1.5	-1.9	1.2	-1.5	-2.3	-1.5
Had menopause	0.8	1.0	4.5	-2.1	-0.2	0.2	0.1	-1.4	0.3	0.5	-1.3	0.7
Forced vital capacity (FVC)	0.8	3.1	19.0	-1.7	1.4	1.3	0.4	0.0	-4.4	0.3	0.5	1.3
Mouth/teeth dental problems	0.8	1.3	3.3	-1.8	-0.4	0.8	0.1	-1.7	0.5	1.0	-1.3	1.2
Diabetes (self-reported)	0.8	1.3	4.3	1.8	-0.8	-0.5	-0.4	-1.2	2.1	-0.7	-0.9	-0.4
Falls in the last year	0.8	1.0	2.0	1.4	-0.9	-0.7	-1.3	-0.7	0.7	-1.4	-0.6	-1.0
Medication: Cholesterol lowering	0.8	1.2	2.4	0.6	-0.8	-1.5	-1.4	-1.0	1.1	-0.4	-0.8	-1.5
Medication: Ventolin 100micrograms inhaler	0.8	1.1	2.4	1.5	-0.5	-1.0	-0.7	0.5	0.8	-1.5	-0.6	-1.4
Birth weight	0.8	1.8	5.0	0.5	-1.4	-1.7	-2.2	-0.9	-1.1	-1.1	-0.7	-1.6
Alcohol intake frequency.	0.8	1.9	4.5	2.1	-0.9	-0.9	-1.4	-0.9	1.8	-1.6	-0.8	-1.2
Illnesses of father: Heart disease	0.8	1.1	3.2	-0.3	-0.6	-1.3	-1.0	-1.3	-0.2	-0.4	-1.2	-1.8
Long-standing illness, disability or infirmity	0.8	1.3	8.6	-0.3	-0.2	-0.7	-0.1	-0.5	2.9	-0.3	-0.8	-1.1
Financial situation satisfaction	0.8	1.0	2.5	-0.7	1.5	0.9	0.8	0.6	0.2	0.9	0.9	1.6
Medication: Paracetamol	0.8	1.2	6.1	2.5	-0.7	-0.3	-0.7	-0.0	1.0	-1.4	-0.2	-0.4
Bipolar Disorder (2018)	0.7	1.2	3.3	0.6	0.2	1.1	-0.0	1.3	0.4	1.7	1.8	1.0
Neuroticism (Nagel 2018)	0.7	1.6	4.8	0.0	-0.2	-1.8	-0.9	1.7	-0.4	-1.3	0.7	-2.2
Worry (Nagel 2018)	0.7	1.4	3.4	-0.3	0.3	-1.6	-1.3	1.8	-0.4	-1.3	0.8	-1.7
Triglycerides	0.7	1.1	3.7	-1.0	-1.3	0.1	-0.4	-1.9	0.3	-0.3	-1.8	0.1
Cardiovascular Disease	0.7	2.3	6.2	2.5	0.6	-0.2	-1.7	-1.2	-0.1	-2.3	-1.5	-1.4
Lung FVC	0.7	3.8	14.0	-2.5	0.6	1.3	1.2	1.1	-3.7	1.4	1.8	1.9
Fed-up feelings	0.7	1.3	4.7	2.2	-0.4	-1.0	-0.4	0.3	0.0	-1.8	-0.3	-1.5
Qualifications: None of the above	0.7	1.5	6.9	2.6	0.1	0.9	-0.3	1.2	1.0	-1.4	0.7	-1.0
Neuroticism score	0.7	1.6	2.9	1.2	1.3	-0.5	-1.1	1.7	-0.5	-1.6	0.9	-1.7
Happiness	0.7	0.8	2.3	0.4	1.5	0.8	1.1	1.0	1.0	-0.0	0.7	0.8
Glaucoma (self-reported)	0.7	0.9	5.0	-0.4	0.1	-0.2	1.4	0.8	2.2	0.2	0.0	0.4
Shortness of breath walking on level ground	0.7	0.9	2.8	0.2	0.7	0.7	1.0	0.8	-1.7	0.1	0.8	1.3
Medication: Blood pressure	0.7	1.2	3.8	0.2	-1.1	-1.2	-0.7	-1.1	1.9	0.2	-1.1	-0.9
Heart disease (mother)	0.7	0.9	5.1	-0.5	0.2	-0.0	-0.4	0.9	2.3	0.7	0.7	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	2.7	0.0	-1.4	-1.1	-0.6	-0.1	-0.3	-1.1	-0.6	-1.7
Friendships satisfaction	0.7	0.8	2.8	1.7	1.3	0.2	0.5	0.7	-0.2	-1.3	0.3	-0.5
Osteoarthritis (self-reported)	0.7	0.9	3.3	-1.3	-0.5	-0.1	0.3	-1.8	0.2	-0.2	-1.7	0.3
Number of self-reported non-cancer illnesses	0.7	1.3	5.2	2.3	-0.3	-0.5	-0.6	0.2	1.0	-1.6	-0.4	-1.3
Mother’s age at death	0.7	0.9	2.2	-0.8	-0.6	-0.3	1.0	-0.8	1.3	1.5	-0.7	0.7
Diastolic blood pressure, automated reading	0.7	2.1	7.1	1.5	-1.0	-0.3	-0.9	-2.7	-1.1	-1.3	-1.9	-0.8
Blood Red Count	0.6	6.2	11.8	2.2	-1.8	-3.1	-3.4	-2.1	-0.7	-2.3	-2.2	-3.4
Blood White Count	0.6	4.7	17.7	4.2	-0.4	-1.0	-1.5	-0.2	2.3	-2.9	-1.7	-2.2
Smoking Status	0.6	1.4	8.2	-0.1	-0.6	0.3	-1.4	-0.0	2.9	1.4	0.2	0.5
Chronotype (morning person)	0.6	1.4	3.4	-0.3	-0.4	-0.2	-1.0	-1.6	-1.3	-1.3	-1.5	-1.9
Supplements: Zinc	0.6	0.6	1.4	0.4	0.1	0.9	1.0	0.4	1.2	0.8	0.6	1.0
Maternal smoking around birth	0.6	0.9	3.7	0.3	0.3	1.2	1.9	0.1	-0.5	0.8	0.3	1.3
Multivitamins +/- minerals	0.6	0.8	2.9	-1.7	-0.6	-1.1	-0.6	-0.2	-0.0	0.7	-0.4	-1.2
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	4.0	-0.5	2.0	0.5	1.1	1.3	-0.3	0.3	0.9	0.3
Pain all over the body in last month	0.6	0.6	1.9	0.4	-0.0	0.8	1.2	0.7	1.4	0.2	0.7	0.7
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.7	1.7	0.8	0.6	0.8	1.2	-0.8	-0.6	0.8	-0.1
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	13.2	-1.2	0.9	0.7	-0.3	-0.7	-3.6	-0.3	-0.3	0.7
Asthma	0.6	1.3	4.1	1.1	0.6	0.4	-0.3	1.6	-2.0	-1.4	0.8	-0.4
Lung cancer (father)	0.6	0.7	2.1	-1.5	-0.2	0.8	1.3	-0.0	0.5	1.1	-0.2	1.0
Medication: Paracetamol	0.6	1.0	5.7	2.4	-0.6	-0.2	-0.3	0.6	0.6	-1.2	0.4	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.6	1.2	0.4	-1.0	-0.8	1.0	0.5	-1.0	-0.1	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.9	1.7	0.4	-0.0	-0.2	1.0	0.4	-1.2	0.5	-0.3
Mouth/teeth dental problems: Loose teeth	0.6	0.7	4.2	2.0	-0.3	-0.3	0.0	0.0	0.1	-1.4	-0.2	-0.4
Emphysema/chronic bronchitis	0.6	0.7	2.9	0.1	1.7	1.0	-0.1	0.7	-0.9	0.3	0.9	0.6
Medication for pain relief, constipation, heartburn	0.6	1.1	3.3	-1.1	0.0	0.9	1.4	0.5	-0.5	1.8	1.0	0.9
Had major operations	0.6	0.7	1.9	-0.9	0.7	-0.4	-0.9	0.7	1.4	1.2	0.3	0.1
Supplements: Vitamin C	0.6	0.8	3.0	0.1	-1.7	-0.4	-0.9	-0.9	0.9	-0.4	-1.0	-0.4
Average weekly red wine intake	0.6	0.8	2.0	-0.2	-1.0	-0.7	-0.9	-1.4	1.0	0.2	-1.1	-1.0
Ever had bowel cancer screening	0.6	0.7	4.5	-0.4	-0.6	-0.1	0.8	0.6	-2.1	-0.5	0.2	-0.1
Asthma (self-reported)	0.6	1.1	4.3	1.2	0.5	0.5	-0.3	1.3	-2.1	-1.3	0.6	-0.5
Medication: Aspirin	0.6	0.8	2.5	0.0	-0.1	-0.5	-1.2	-0.3	-1.6	-1.2	-0.3	-1.0
Illnesses of father: None of the above (group 1)	0.6	0.8	2.2	-0.5	-0.1	0.9	1.5	0.6	-0.8	-0.1	0.9	1.4
Medication: Atorvastatin	0.6	0.8	2.6	0.3	-1.6	-1.3	-0.4	0.2	0.3	-0.9	-0.6	-1.1
Ever smoked	0.6	1.1	2.5	-0.4	-1.6	-1.1	-1.3	-0.5	1.3	0.8	-0.5	-1.1
Cholesterol lowering medication	0.6	0.9	2.3	1.4	0.2	-0.3	-1.5	-0.0	-1.0	-1.3	0.0	-1.1
Pain experienced in last month	0.6	1.0	4.2	-1.7	-0.8	-0.0	0.7	0.0	-0.3	2.1	0.4	0.2
Bipolar Disorder or Schizophrenia	0.5	1.2	3.7	1.9	0.1	1.7	0.6	1.1	0.7	0.1	1.1	1.1
Schizophrenia (2018)	0.5	1.0	4.2	2.0	-0.0	1.3	0.8	0.4	0.6	-1.3	-0.0	0.5
Age at First Birth	0.5	0.8	3.5	-1.9	-0.2	-0.2	0.2	-1.1	-1.0	0.5	-1.0	-0.3
HbA1C	0.5	0.6	1.3	0.9	-1.1	-0.9	-0.4	0.5	-0.1	-1.0	0.0	-1.1
Waist Hip Ratio (WHR)	0.5	2.5	11.4	3.4	0.5	1.9	0.6	1.0	1.9	-1.3	0.2	0.3
Neuroticism	0.5	1.2	3.8	0.1	0.8	-0.6	-0.8	2.0	-0.6	-1.2	0.9	-1.4
Frequency of depressed mood in last 2 weeks	0.5	0.7	3.4	-0.3	1.9	0.6	0.8	1.1	0.5	0.2	0.4	0.8
Ever had hysterectomy (womb removed)	0.5	0.6	2.6	-1.6	0.4	0.7	0.2	0.7	-0.6	0.1	0.8	0.6
Angina	0.5	0.7	2.6	1.6	0.0	-0.1	-1.1	0.9	0.4	-0.6	0.7	-0.8
Vitamin and mineral supplements	0.5	0.7	2.7	1.6	0.9	1.0	0.3	-0.0	-0.4	-0.4	0.3	0.9
Diabetes (father)	0.5	0.6	1.4	1.1	1.2	0.2	-0.8	0.9	0.4	0.6	0.6	-0.6
Relative age voice broke	0.5	0.8	2.2	-1.1	0.5	0.7	1.5	0.3	0.5	1.1	0.4	1.1
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	2.4	-1.6	-0.9	-0.5	-0.1	-0.7	-0.2	0.5	-0.2	-0.6
Serious illness, injury or assault to yourself	0.5	0.6	2.2	-0.2	0.7	0.4	-0.6	1.5	-0.1	-0.1	1.4	-0.2
Medication: Atenolol	0.5	0.6	1.7	1.3	0.0	-0.1	-0.4	1.0	1.2	-0.2	1.0	-0.4
Sitting height	0.5	3.5	15.8	-4.0	-1.2	-1.5	-0.5	-1.8	-2.5	0.6	-1.3	0.2
Number of incorrect matches in round	0.5	0.7	3.4	1.8	1.1	0.8	0.1	-0.2	0.3	-1.0	-0.6	0.1
Past tobacco smoking	0.5	0.9	3.7	0.5	1.2	0.5	1.2	0.1	-1.9	-0.8	0.1	0.5
Hair/balding pattern: Pattern 2	0.5	0.6	1.4	-0.9	0.5	0.5	1.1	1.2	-0.2	0.6	1.0	0.6
Had other major operations	0.5	0.6	1.5	-0.6	1.2	0.9	0.4	0.7	-1.0	0.5	0.7	0.3
Time employed in main current job	0.5	0.6	3.4	-0.8	-0.7	-0.7	-0.4	-0.2	-1.8	-0.2	0.1	0.0
Father’s age at death	0.5	0.7	3.8	1.9	-0.5	-0.5	-0.9	0.5	0.2	-0.9	0.5	-0.3
Hair/balding pattern: Pattern 3	0.5	0.7	2.6	0.4	-0.8	-1.0	-1.6	-0.2	1.3	0.2	-0.2	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.3	1.1	0.1	-0.5	-1.1	-0.7	0.3	-1.2	-0.7	-0.5
Qualifications: O levels/GCSEs or equivalent	0.5	0.9	3.1	-1.6	-0.2	0.6	0.3	-0.4	0.2	1.2	-0.0	1.8
Headache pain in last month	0.5	0.9	4.0	0.8	0.2	-0.0	0.4	0.7	-1.2	-2.0	-0.3	-0.9
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.7	0.2	0.8	1.1	0.8	1.3	-1.1	-0.5	0.9	0.9
Forced vital capacity (FVC), Best measure	0.5	1.8	10.2	-1.2	1.3	1.1	-0.0	0.3	-3.2	0.3	0.5	1.0
Age at first live birth	0.5	0.8	2.8	-1.7	-0.5	-1.1	0.1	-0.9	-0.9	0.4	-0.8	-0.9
Pulse wave peak to peak time	0.5	0.6	2.7	-0.0	0.5	-0.5	-0.2	-0.6	-1.6	-0.8	-0.5	-0.9
Medication: Ibuprofen	0.5	0.7	1.7	1.3	0.3	-0.3	-0.8	-0.5	0.9	-1.2	-0.9	-0.4
Suffer from ‘nerves’	0.5	0.7	1.5	0.4	0.2	-0.7	-0.9	0.9	-1.1	-1.1	0.4	-1.2
Chest pain or discomfort	0.5	0.7	1.5	0.8	-1.1	-1.0	-0.4	0.5	0.1	-1.2	-0.3	-1.2
Family relationship satisfaction	0.5	0.7	2.5	0.3	0.9	0.3	1.6	1.0	1.0	0.4	0.4	0.4
Smoking status: Previous	0.5	0.7	3.2	-0.3	-0.7	0.1	-1.5	-0.3	1.8	0.6	-0.1	-0.2
Eye problems/disorders: Cataract	0.5	0.6	2.0	-1.0	-0.4	-0.2	1.4	0.9	-0.5	0.7	0.3	-0.1
Breast cancer (self-reported)	0.5	0.7	1.9	1.4	-0.2	-0.0	-0.6	-0.1	1.3	-0.8	-0.1	-1.1
Medication: Gliclazide	0.5	0.5	2.2	1.5	-0.2	-0.6	-0.2	-1.0	0.1	0.1	-0.6	-0.9
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.1	-0.3	-0.5	0.4	0.1	1.1	-1.4	-1.2	0.6	0.3
Alcohol drinker status: Never	0.5	0.6	3.2	0.1	-0.9	-0.2	0.4	-0.7	1.8	0.3	-0.5	0.4
Myopia	0.5	0.7	2.1	0.3	1.5	0.8	-0.6	0.6	1.0	0.8	0.7	0.6
Depression (Nagel 2018)	0.4	0.6	1.7	-0.9	1.0	0.5	0.6	1.0	0.1	0.5	0.6	1.3
Schizophrenia vs Biploar Disorder	0.4	0.5	1.2	0.1	-0.9	-0.1	0.8	-0.9	-1.1	-0.7	-0.8	-0.1
Major Depression (MDD)	0.4	0.5	1.8	0.3	-0.6	-1.0	-0.3	0.3	0.4	-1.3	-0.4	-0.5
Reaction Time	0.4	0.8	2.3	-0.0	0.8	0.7	0.4	1.3	-1.5	0.3	1.1	0.4
Breast Cancer	0.4	1.0	3.8	0.7	-0.5	-0.2	0.2	1.9	0.4	0.9	2.0	0.2
Mean Putamen Volume	0.4	0.5	2.5	0.7	0.6	0.7	-1.6	0.0	0.4	-0.4	0.0	0.0
LDL Cholesterol	0.4	0.6	1.3	-1.1	-0.4	0.7	0.8	-1.1	-0.0	0.4	-0.7	1.1
Primary Biliary Cirrhosis	0.4	0.6	1.8	-0.9	-0.7	-1.0	0.4	-0.2	-0.6	1.4	-0.1	-0.7
Schizophrenia (2014)	0.4	1.0	3.1	1.5	-0.0	1.8	0.9	0.2	-0.6	0.2	0.6	1.2
Ulcerative Colitis	0.4	0.6	1.9	-0.1	0.4	0.3	1.2	-0.3	0.7	1.4	-0.3	1.2
Blood Eosinophil Count	0.4	2.9	17.1	1.7	-1.0	-0.8	-0.3	-0.4	4.1	-0.9	-0.9	-1.6
Blood Platelet Count	0.4	4.8	15.8	4.0	0.1	0.9	-2.0	-3.0	-0.9	-2.5	-2.4	-1.0
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	1.7	0.0	0.7	-0.5	-0.1	1.1	1.3	-0.0	0.6	-1.0
Pack years adult smoking proportion	0.4	0.6	1.7	1.3	-0.0	0.9	0.9	-0.3	1.0	-0.7	-0.2	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.6	-0.9	1.1	0.5	1.3	0.3	-0.2	-0.1	-0.0	0.7
Taking other prescription medications	0.4	0.6	2.4	1.1	0.4	-0.2	-0.8	0.1	-0.0	-1.5	-0.2	-1.0
Qualifications: CSEs or equivalent	0.4	0.5	1.3	0.5	0.2	0.7	1.0	0.6	0.6	0.4	0.7	1.1
Financial difficulties in last 2 years	0.4	0.5	1.3	-0.6	0.9	-0.4	1.1	0.3	-1.1	0.6	0.5	0.2
Worrier / anxious feelings	0.4	0.7	2.1	-1.4	0.7	-0.4	-0.5	1.4	0.5	-0.1	1.0	-0.3
Mouth/teeth dental problems: Dentures	0.4	0.7	1.8	0.7	-1.3	-1.1	-0.6	-0.4	0.0	-0.9	-0.1	-1.4
Illnesses of mother	0.4	0.4	1.8	0.0	0.5	1.2	0.3	-0.1	-1.4	-0.4	0.2	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	8.2	-1.2	0.8	0.6	-0.5	-0.6	-2.9	-0.0	-0.3	0.6
Pulse wave Arterial Stiffness index	0.4	0.5	2.5	-0.0	-0.5	0.4	0.1	0.4	1.6	0.6	0.3	0.8
Standing height	0.4	3.5	6.2	-2.4	-1.9	-2.4	-1.2	-2.4	-1.1	-1.0	-2.5	-0.8
Birth weight of first child	0.4	0.7	1.7	-1.3	0.5	0.1	0.6	0.1	-0.3	1.3	0.2	1.3
Gout (self-reported)	0.4	0.5	1.0	-0.7	-0.6	-0.7	-0.9	-0.7	0.8	-0.2	-1.0	0.2
Number of full brothers	0.4	0.5	1.6	-0.5	-1.2	-0.4	-0.7	0.4	0.7	-0.9	-0.3	-0.9
Worry too long after embarrassment	0.4	0.6	1.6	0.8	0.8	-0.5	-0.3	1.1	0.2	-1.2	0.5	-0.7
Health satisfaction	0.4	0.5	1.5	1.2	-0.5	-0.9	0.7	-0.3	0.6	-0.8	-0.4	-0.7
Eye problems/disorders: None of the above	0.4	0.4	1.1	-0.4	0.9	0.8	-0.2	0.1	-0.8	0.6	0.5	1.0
Neck or shoulder pain in last month	0.4	0.5	2.0	0.8	-0.3	-0.4	-0.8	0.1	0.4	-1.4	-0.3	-0.8
Angina (self-reported)	0.4	0.5	1.5	1.2	0.1	-0.0	-1.1	0.9	0.2	-0.4	0.8	-0.6
Medication: Aspirin	0.4	0.5	1.5	-0.5	-0.0	-0.6	-0.8	-0.1	-1.2	-0.9	-0.2	-0.9
Mood swings	0.4	0.7	2.6	0.5	1.0	-0.3	-0.5	1.6	0.5	-0.7	0.8	-1.0
Smoking status: Current	0.4	0.6	1.2	0.7	0.2	0.7	0.5	0.8	1.1	1.0	0.8	1.1
Average weekly champagne plus white wine intake	0.4	0.5	2.2	0.3	-0.7	-0.7	-1.5	-0.6	-0.1	-0.8	-0.5	-0.6
Wears glasses or contact lenses	0.4	0.5	1.6	-1.1	-1.3	-0.5	-0.6	-0.4	-0.1	-0.9	-0.3	0.3
Eye problems/disorders: Glaucoma	0.4	0.5	2.6	-0.7	-0.5	-0.4	1.0	0.6	1.6	-0.0	0.1	-0.0
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.6	0.8	-0.3	-0.7	0.3	-0.8	0.4	-1.3	-1.0	-0.3
High cholesterol (Self-reported)	0.4	0.7	1.7	0.9	1.3	-0.1	-1.3	0.0	-0.9	-0.5	0.3	-0.9
Number of operations (self-reported)	0.4	0.6	1.4	-1.1	0.5	0.6	-1.1	0.7	0.0	1.2	0.7	0.4
Irritability	0.4	0.7	2.5	0.8	0.2	-0.9	-1.2	0.1	1.6	-0.3	0.0	-1.1
Fractured/broken bones in last 5 years	0.4	0.5	1.5	0.9	0.1	-0.3	0.0	-0.3	-0.0	-1.2	-0.7	-1.1
Heart disease (siblings)	0.4	0.5	2.2	-0.6	-1.5	-0.6	-0.3	0.7	0.9	0.1	0.3	-0.6
Pack years of smoking	0.4	0.6	1.8	1.3	-0.3	0.6	0.9	-0.2	1.2	-0.7	-0.3	0.6
Depressed Affect (Nagel 2018)	0.3	0.7	2.4	-0.0	-0.3	-0.9	-0.2	1.5	-0.2	-0.7	0.6	-1.4
Alzheimer’s Disease (including proxy)	0.3	0.4	1.0	-0.4	0.1	-0.9	0.9	0.8	-1.0	-0.3	-0.0	-0.6
Ulcerative Colitis (UC)	0.3	0.6	1.6	0.9	0.5	-0.1	1.3	0.6	0.9	0.9	0.1	0.8
HDL Cholesterol	0.3	0.6	1.3	-0.3	-0.4	-1.1	-0.3	1.0	-0.0	0.7	1.0	-1.0
Heel T-Score	0.3	2.0	5.4	-0.5	-1.2	-2.0	-2.3	-1.4	0.1	-0.5	-1.2	-1.8
Hypothyroidism (self reported)	0.3	0.6	1.7	0.3	0.2	1.3	0.5	1.1	-0.4	0.4	1.1	0.7
Systolic blood pressure, automated reading	0.3	0.8	3.4	0.6	-1.0	-0.3	-0.8	-1.8	0.3	-0.2	-1.1	-0.0
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.3	1.1	0.0	0.2	0.9	-0.0	-0.1	-0.6	-0.1	-0.4
Hand grip strength (right)	0.3	0.8	1.8	0.5	-0.1	-1.0	-0.9	-0.7	-1.3	-0.7	-1.0	-1.2
Current tobacco smoking	0.3	0.5	1.7	1.3	-0.1	0.5	0.1	0.2	1.3	0.4	0.3	0.5
Average weekly fortified wine intake	0.3	0.4	0.9	0.2	0.6	0.1	0.5	0.6	0.5	0.9	0.8	0.7
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.9	0.5	0.3	0.4	-0.1	0.9	-0.8	-1.0	0.5	0.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.3	0.8	0.1	-0.0	0.7	1.1	0.9	-0.5	0.4	-0.1
Qualifications: A levels/AS levels or equivalent	0.3	0.7	2.9	-1.7	-0.3	-0.1	0.7	0.7	0.1	1.0	0.5	0.8
Exposure to tobacco smoke at home	0.3	0.4	1.3	-0.1	-0.9	-0.9	0.6	0.1	1.2	-0.2	-0.2	-0.2
Hair/balding pattern: Pattern 4	0.3	0.7	2.0	1.4	0.2	0.6	0.1	-0.5	-1.0	-1.4	-0.5	-0.5
Exposure to tobacco smoke outside home	0.3	0.4	1.7	0.1	-0.4	-0.1	0.2	-0.6	1.3	-0.5	-0.9	0.1
Wheeze or whistling in the chest in last year	0.3	0.5	1.5	1.2	-0.3	-0.2	0.5	1.2	-0.6	-0.0	0.7	-0.3
Number of children fathered	0.3	0.4	1.0	-0.5	-0.8	-0.5	0.6	1.0	0.6	0.3	0.6	-0.2
Overall health rating	0.3	0.5	1.7	1.3	0.5	-0.3	-0.3	0.2	1.1	-1.1	-0.1	-0.5
Age at last live birth	0.3	0.4	1.2	-1.1	-0.4	-0.6	0.7	-0.4	0.5	0.9	-0.4	-0.4
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.0	-0.8	-0.4	0.3	1.0	-0.7	-0.8	-0.5	-0.4	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	4.1	-0.6	-0.3	-0.3	0.4	-0.9	-2.0	-0.1	-0.7	-0.4
Qualifications: nursing, teaching	0.3	0.4	2.1	-1.5	-0.4	-0.3	0.0	-0.9	-0.5	0.3	-0.4	0.0
Medication for cholesterol	0.3	0.5	1.6	-1.2	-0.6	0.0	0.5	-0.6	0.6	1.3	-0.3	0.3
Miserableness	0.3	0.5	1.3	1.1	0.6	0.4	0.0	1.0	-0.6	-0.9	0.5	-0.6
Guilty feelings	0.3	0.4	1.3	0.5	1.1	0.1	0.4	1.0	-0.6	-0.3	0.4	-0.9
Ever taken oral contraceptive pill	0.3	0.3	0.7	-0.2	0.8	0.3	0.1	0.7	-0.7	0.4	0.8	-0.3
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.1	-0.4	-1.0	-0.1	-0.7	-0.4	0.9	-0.6	-0.3	0.1
Basal cell carcinoma (self-reported)	0.3	0.3	1.7	0.1	-0.2	-0.5	-0.0	0.5	1.3	-0.2	0.1	-0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.4	0.6	-0.6	-1.0	0.2	-0.1	1.2	-0.8	-0.6	-0.7
Ovarian Cancer	0.2	0.3	0.7	0.2	0.0	-0.0	0.4	-0.8	-0.7	-0.6	-0.8	-0.2
Rheumatoid Arthritis	0.2	0.3	1.0	0.2	0.7	0.9	0.1	0.1	-0.4	0.0	0.2	1.0
Lung FEV1/FVC ratio	0.2	0.8	1.9	0.4	-0.4	0.4	0.5	-1.4	-1.3	-1.3	-1.1	-0.1
Medication for hormone replacement therapy	0.2	0.2	0.9	-0.1	-0.4	-0.4	-0.1	0.9	-0.0	0.3	0.9	0.0
Medication: Co-codamol	0.2	0.2	1.0	0.2	-0.6	-0.3	1.0	0.0	-0.3	0.1	-0.0	-0.3
Severe depression (siblings)	0.2	0.3	1.2	0.4	0.3	-0.2	0.3	1.1	-0.3	0.0	0.8	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.0	0.4	-0.1	-0.8	-1.4	-0.3	-0.1	-1.2	-0.7	-0.3
Chronic bronchitis/emphysema (father)	0.2	0.3	0.9	-0.3	0.4	0.4	0.4	0.1	1.0	0.9	0.0	0.1
Alcohol usually taken with meals	0.2	0.3	0.8	0.9	0.1	0.3	-0.8	-0.1	0.9	-0.1	-0.2	0.8
Hearing difficulty/problems with background noise	0.2	0.4	2.0	-0.5	-1.4	-0.3	0.4	-0.5	0.2	-0.4	-0.5	-0.3
Fluid intelligence score	0.2	0.4	0.9	-0.2	-0.6	-0.6	0.5	-1.0	0.5	-0.0	-0.9	-0.3
Number of live births	0.2	0.2	1.0	1.0	-0.0	0.5	0.8	0.4	-0.1	-0.2	0.1	-0.3
Comparative body size at age 10	0.2	0.5	1.4	0.0	0.9	0.4	0.6	-0.4	1.1	-0.4	-0.2	1.2
Migraine (self-reported)	0.2	0.3	0.8	0.2	-0.8	0.2	0.9	-0.3	0.5	0.7	0.3	0.5
Mean time to correctly identify matches	0.2	0.3	1.3	-0.4	-0.5	-0.2	-0.1	0.7	-1.1	-0.3	0.3	-0.3
Pulse rate, automated reading	0.2	0.5	1.5	0.5	0.6	0.6	1.0	-0.5	-0.9	0.1	-0.2	1.2
Comparative height size at age 10	0.2	0.9	3.3	-1.8	-0.6	0.1	0.1	-0.9	0.1	1.2	-0.5	1.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	1.0	0.4	0.2	0.4	-0.1	0.3	0.7	0.4	0.1	1.0
Loneliness, isolation	0.2	0.3	1.0	-0.5	0.8	-0.3	-0.1	1.0	0.5	-0.6	0.5	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.6	-0.2	-0.9	-0.0	0.2	0.2	-1.3	-0.4	0.2	0.6
Commuting to job workplace: Public transport	0.2	0.2	0.4	-0.6	0.0	0.0	-0.5	0.5	-0.6	0.3	0.6	0.6
Medication: Blood pressure	0.2	0.3	1.2	0.3	0.8	-0.1	-1.1	-0.1	-0.3	-0.9	-0.2	0.0
Medication: Lisinopril	0.2	0.2	0.5	-0.7	0.4	-0.5	-0.1	0.5	-0.4	0.1	0.2	0.6
Height	0.1	1.1	4.7	-2.2	-0.7	-1.4	0.3	0.7	-1.2	0.6	0.6	-0.5
Hair Pigment	0.1	2.5	6.0	0.8	-1.2	-1.2	-2.4	-1.3	1.1	-2.2	-1.7	-1.5
Tanning	0.1	1.5	7.3	-0.8	1.5	1.4	0.7	0.3	-2.7	0.7	0.4	0.4
Hand grip strength (left)	0.1	0.3	0.6	0.7	0.1	-0.7	-0.8	0.6	-0.2	-0.3	0.0	-0.4
Sensitivity / hurt feelings	0.1	0.1	0.3	0.6	0.4	-0.3	-0.5	0.1	0.2	-0.5	-0.3	-0.3
Relative age of first facial hair	0.1	0.2	0.7	-0.8	-0.4	0.5	0.6	0.2	0.4	0.1	0.1	0.1
Medication: Levothyroxine sodium	0.1	0.1	0.4	0.4	-0.4	0.2	0.6	-0.0	0.1	-0.1	-0.3	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.9	0.9	0.2	-0.4	-0.5	0.9	0.2	-0.9	0.1	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.5	0.0	0.7	-0.5	0.7	0.4	-0.6	-0.2	0.0	-0.1
Pulse rate	0.1	0.2	0.6	0.7	0.4	0.2	-0.0	0.2	-0.8	0.1	0.6	0.6
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.6	0.5	-0.4	0.8	0.3	0.7	0.2	0.2	0.7	0.2
Qualifications: College or University degree	0.1	0.4	1.2	-1.1	0.5	0.5	0.1	0.4	-0.1	0.8	0.6	0.6
Mineral and other dietary supplements	0.1	0.2	0.6	0.8	0.7	-0.3	-0.0	-0.3	-0.1	0.5	0.0	-0.5
Risk taking	0.1	0.1	0.3	0.1	-0.3	-0.4	0.3	0.4	0.4	0.1	0.5	-0.1
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.4	-0.4	-0.5	-0.6	0.3	0.2	0.0	-0.2	0.2	-0.2
Systolic Blood Pressure	0.0	0.2	0.6	0.4	0.5	0.2	-0.7	-0.7	-0.1	-0.1	-0.5	0.3

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