TWAS
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Usage
Models
Genes
Traits
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Traits
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Trunk fat-free mass
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chr10:95,019,584-97,070,115
Best TWAS P=9e-09 · Best GWAS P=1.86e-14 conditioned to 2.78e-08
95M
95.5M
96M
96.5M
97M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
5
The Cancer Genome Atlas
Prostate Adenocarcinoma
TBC1D12
0.04
0.04
blup
63
0.03
3.9e-04
4.9
5.8
9.0e-09
0.49
0.03
0.93
TRUE
2
GTEx
Ovary
HELLS
0.15
0.04
lasso
5
0.09
3.1e-03
5.0
5.6
2.1e-08
0.34
0.11
0.41
FALSE
1
CommonMind
Brain Pre-frontal Cortex
HELLS
0.04
0.04
enet
12
0.04
5.1e-06
4.9
5.5
4.2e-08
0.41
0.97
0.01
FALSE
3
GTEx
Testis
PIPSL
0.14
0.00
enet
21
0.00
3.0e-01
2.2
-5.4
6.3e-08
-0.38
0.03
0.53
FALSE
4
The Cancer Genome Atlas
Cervical Squamous Cell Carcinoma
TBC1D12
0.04
0.01
blup
63
0.03
8.3e-03
4.5
-5.2
2.3e-07
-0.43
0.03
0.56
FALSE