Best TWAS P=9e-09 · Best GWAS P=1.86e-14 conditioned to 2.78e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HELLS | 0.04 | 0.04 | enet | 12 | 0.04 | 5.1e-06 | 4.9 | 5.5 | 4.2e-08 | 0.41 | 0.97 | 0.01 | FALSE |
| 2 | GTEx | Ovary | HELLS | 0.15 | 0.04 | lasso | 5 | 0.09 | 3.1e-03 | 5.0 | 5.6 | 2.1e-08 | 0.34 | 0.11 | 0.41 | FALSE |
| 3 | GTEx | Testis | PIPSL | 0.14 | 0.00 | enet | 21 | 0.00 | 3.0e-01 | 2.2 | -5.4 | 6.3e-08 | -0.38 | 0.03 | 0.53 | FALSE |
| 4 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | TBC1D12 | 0.04 | 0.01 | blup | 63 | 0.03 | 8.3e-03 | 4.5 | -5.2 | 2.3e-07 | -0.43 | 0.03 | 0.56 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TBC1D12 | 0.04 | 0.04 | blup | 63 | 0.03 | 3.9e-04 | 4.9 | 5.8 | 9.0e-09 | 0.49 | 0.03 | 0.93 | TRUE |