[Hub]/) : Traits : Trunk fat-free mass :

chr16:66,514,962-68,988,905

Best TWAS P=7.67e-14 · Best GWAS P=1.47e-13 conditioned to 1.02e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum KIAA0895L 0.47 0.06 enet 39 0.13 1.5e-04 -0.75 -5.6 2.6e-08 -0.04 0.39 0.04 FALSE
2 GTEx Brain Cerebellum PSMB10 0.11 0.03 lasso 4 0.05 1.6e-02 -0.94 5.5 3.2e-08 0.28 0.09 0.06 FALSE
3 GTEx Lung NFATC3 0.04 0.01 lasso 4 0.01 4.1e-02 5.96 -6.3 3.5e-10 -0.32 0.29 0.12 FALSE
4 GTEx Spleen NFATC3 0.29 0.30 lasso 2 0.25 3.3e-07 5.40 -5.3 1.3e-07 -0.31 0.40 0.15 FALSE
5 GTEx Thyroid PLA2G15 0.06 0.04 enet 5 0.04 5.7e-04 6.43 6.5 9.9e-11 0.38 0.44 0.43 TRUE
6 The Cancer Genome Atlas Breast Invasive Carcinoma KCTD19 0.02 0.02 blup 29 0.03 3.5e-06 -4.97 -5.9 2.8e-09 -0.03 0.01 0.98 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma NFATC3 0.22 0.05 lasso 3 0.06 3.6e-04 3.44 -5.9 3.8e-09 -0.35 0.00 0.98 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma AGRP 0.06 0.00 enet 9 0.02 5.3e-03 -2.32 -5.4 8.2e-08 -0.09 0.00 0.33 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NFATC3 0.11 0.04 enet 4 0.04 2.8e-05 6.72 -6.4 1.2e-10 -0.36 0.00 0.99 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma NFATC3 0.23 0.05 lasso 2 0.06 8.5e-08 6.72 -5.8 6.0e-09 -0.31 0.00 1.00 FALSE
11 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma AGRP 0.11 0.01 enet 6 0.07 2.5e-05 6.42 -7.5 7.7e-14 -0.12 0.00 0.78 TRUE
12 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma NFATC3 0.26 0.09 enet 4 0.13 9.8e-06 6.72 -5.3 1.3e-07 -0.29 0.01 0.96 FALSE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors NFATC3 0.46 0.16 lasso 4 0.20 1.7e-07 -3.37 -5.5 3.7e-08 -0.33 0.01 0.98 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma C16orf48 0.04 0.02 blup 17 0.04 8.5e-05 -2.45 6.2 7.3e-10 0.37 0.01 0.49 FALSE