Best TWAS P=4.97e-09 · Best GWAS P=1.8e-07 conditioned to 0.503
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | APOC1P1 | 0.05 | 0.03 | blup | 37 | 0.03 | 5.2e-04 | 2.3 | -5.5 | 3.5e-08 | 0.41 | 0.11 | 0.06 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | APOC2 | 0.27 | 0.25 | enet | 14 | 0.24 | 3.8e-14 | -5.0 | 5.2 | 2.3e-07 | -0.93 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | APOC4 | 0.06 | 0.03 | blup | 34 | 0.04 | 8.4e-06 | -5.0 | -5.8 | 5.0e-09 | 0.83 | 0.01 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | APOC4 | 0.09 | 0.08 | enet | 9 | 0.12 | 1.9e-11 | -5.2 | -5.1 | 2.8e-07 | 0.87 | 0.00 | 0.99 | FALSE |