[Hub]/) : Traits : Trunk fat-free mass : ← →

chr19:46,276,056-51,224,297

Best TWAS P=1.94e-12 · Best GWAS P=5.01e-19 conditioned to 4.73e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Cells Transformed fibroblasts	TBC1D17	0.11	0.03	enet	23	0.04	6.5e-04	-5.5	7.0	1.9e-12	-0.02	0.16	0.82	TRUE
23	METSIM	Adipose	SAE1	0.12	0.04	lasso	5	0.07	1.7e-10	-4.1	-6.3	2.9e-10	0.61	0.59	0.41	TRUE
19	GTEx	Testis	NTN5	0.16	0.02	enet	23	0.06	9.6e-04	-3.7	-6.3	3.4e-10	-0.02	0.02	0.79	TRUE
35	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	GRLF1	0.04	0.04	blup	51	0.03	7.0e-05	4.8	6.0	2.5e-09	-0.04	0.43	0.09	TRUE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	LIN7B	0.02	0.00	enet	7	0.02	5.1e-05	5.3	-5.6	2.3e-08	-0.04	0.01	0.94	TRUE
17	GTEx	Small Intestine Terminal Ileum	PNMAL1	0.40	0.00	enet	11	0.15	2.7e-04	5.2	5.5	4.2e-08	-0.01	0.02	0.66	TRUE
14	GTEx	Skin Sun Exposed Lower leg	CCDC9	0.13	0.00	lasso	5	0.00	2.2e-01	2.4	-5.2	1.8e-07	0.23	0.11	0.21	TRUE
9	GTEx	Esophagus Mucosa	AP2A1	0.18	0.09	enet	8	0.13	7.7e-09	-5.8	-7.0	3.3e-12	-0.01	0.02	0.98	FALSE
12	GTEx	Nerve Tibial	AP2A1	0.16	0.05	lasso	4	0.07	1.3e-05	-6.2	-6.9	4.6e-12	0.02	0.01	0.99	FALSE
18	GTEx	Stomach	VRK3	0.10	-0.01	enet	10	-0.01	7.3e-01	3.8	6.5	7.7e-11	0.00	0.05	0.40	FALSE
7	GTEx	Colon Sigmoid	PRR12	0.20	0.01	lasso	8	0.00	4.9e-01	3.8	6.3	3.3e-10	0.02	0.04	0.28	FALSE
16	GTEx	Skin Sun Exposed Lower leg	AP2A1	0.15	0.08	enet	10	0.07	1.9e-06	-6.2	-6.2	4.2e-10	-0.01	0.01	0.99	FALSE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	AP2A1	0.04	0.03	lasso	4	0.04	1.8e-08	-6.2	6.0	1.5e-09	-0.02	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PNKP	0.15	0.16	enet	23	0.16	7.0e-19	-5.9	-6.0	2.3e-09	0.03	0.43	0.57	FALSE
11	GTEx	Muscle Skeletal	AKT1S1	0.10	0.09	lasso	3	0.08	1.9e-08	-5.8	5.8	5.7e-09	-0.05	0.46	0.54	FALSE
1	CommonMind	Brain Pre-frontal Cortex	MED25	0.05	0.01	blup	361	0.02	2.2e-03	-6.4	-5.7	1.0e-08	0.03	0.02	0.90	FALSE
21	GTEx	Whole Blood	PNKP	0.14	0.10	enet	12	0.12	1.5e-11	-5.6	-5.7	1.5e-08	-0.04	0.53	0.47	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	SAE1	0.21	0.09	lasso	3	0.07	2.0e-03	-4.4	-5.7	1.6e-08	0.77	0.06	0.67	FALSE
6	GTEx	Colon Sigmoid	MED25	0.28	0.22	enet	10	0.17	1.2e-06	-6.6	-5.6	2.4e-08	0.07	0.01	0.99	FALSE
29	The Cancer Genome Atlas	Breast Invasive Carcinoma	NTN5	0.02	0.01	enet	11	0.01	7.6e-04	-3.9	-5.5	3.3e-08	0.00	0.04	0.74	FALSE
10	GTEx	Muscle Skeletal	FUZ	0.09	0.06	enet	9	0.03	3.2e-04	-6.6	-5.5	3.7e-08	0.01	0.00	1.00	FALSE
20	GTEx	Testis	AC006942.4	0.24	0.03	enet	9	0.10	3.9e-05	-2.8	5.4	5.9e-08	0.00	0.02	0.96	FALSE
24	YFS	Blood	PNKP	0.22	0.28	enet	47	0.30	3.9e-101	-5.6	-5.4	6.8e-08	-0.03	0.50	0.50	FALSE
33	The Cancer Genome Atlas	Lung Adenocarcinoma	PNKP	0.03	0.00	blup	46	0.02	4.0e-03	-5.6	-5.4	6.8e-08	-0.05	0.02	0.09	FALSE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	MED25	0.01	0.00	blup	47	0.02	2.9e-04	3.6	-5.4	7.1e-08	0.05	0.06	0.69	FALSE
31	The Cancer Genome Atlas	Colon Adenocarcinoma	SNRNP70	0.05	0.02	lasso	3	0.02	2.9e-02	4.1	-5.4	7.9e-08	-0.02	0.02	0.55	FALSE
22	METSIM	Adipose	PNMAL1	0.24	0.27	bslmm	380	0.28	2.9e-41	5.2	5.3	9.2e-08	-0.01	0.00	1.00	FALSE
36	The Cancer Genome Atlas	Thyroid Carcinoma	IL4I1	0.07	0.01	blup	63	0.03	7.6e-04	-5.8	5.3	1.0e-07	-0.02	0.03	0.71	FALSE
15	GTEx	Skin Sun Exposed Lower leg	NTN5	0.11	0.09	enet	18	0.05	6.2e-05	-3.9	-5.3	1.1e-07	0.02	0.92	0.06	FALSE
32	The Cancer Genome Atlas	Brain Lower Grade Glioma	TBC1D17	0.06	0.03	blup	50	0.02	9.5e-04	-5.6	5.2	1.5e-07	-0.02	0.08	0.87	FALSE
3	GTEx	Adipose Visceral Omentum	PNMAL1	0.18	0.15	lasso	2	0.14	9.7e-08	5.2	5.2	1.6e-07	-0.02	0.00	1.00	FALSE
8	GTEx	Colon Transverse	PNMAL1	0.35	0.28	lasso	4	0.27	2.0e-13	5.2	5.2	1.7e-07	-0.02	0.00	1.00	FALSE
25	YFS	Blood	SAE1	0.07	0.02	enet	18	0.05	3.6e-16	-8.0	-5.2	2.1e-07	0.56	0.75	0.25	FALSE
13	GTEx	Ovary	PNMAL1	0.51	0.36	lasso	8	0.34	4.1e-09	5.2	5.2	2.3e-07	-0.01	0.00	0.99	FALSE
30	The Cancer Genome Atlas	Breast Invasive Carcinoma	TSKS	0.02	0.02	blup	41	0.03	2.1e-06	-1.9	-5.2	2.5e-07	-0.02	0.65	0.25	FALSE
34	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CGB	0.09	0.05	enet	3	0.06	5.3e-07	-4.1	-5.1	3.0e-07	-0.04	0.00	1.00	FALSE