[Hub]/) : Traits : Trunk fat-free mass : ← →

chr22:41,232,594-43,226,599

Best TWAS P=4.92e-10 · Best GWAS P=1.19e-15 conditioned to 1.58e-09

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Lung	RP5-821D11.7	0.08	0.02	enet	21	0.04	6.6e-04	4.2	6.2	4.9e-10	-0.40	0.53	0.04	TRUE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	WBP2NL	0.06	0.04	blup	140	0.03	9.6e-05	-5.1	6.1	9.5e-10	-0.53	0.58	0.24	FALSE
2	GTEx	Adipose Subcutaneous	CYP2D6	0.26	0.10	enet	34	0.20	1.2e-16	-3.5	-6.0	2.0e-09	0.45	1.00	0.00	FALSE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CSDC2	0.25	0.01	enet	11	0.06	2.3e-03	-3.3	-5.8	6.7e-09	0.21	0.00	0.00	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	WBP2NL	0.10	0.04	blup	140	0.05	1.8e-06	-3.8	5.8	8.8e-09	-0.40	0.98	0.00	FALSE
12	GTEx	Spleen	CCDC134	0.23	0.00	enet	14	0.09	2.7e-03	-5.1	5.7	1.1e-08	-0.40	0.07	0.07	FALSE
5	GTEx	Breast Mammary Tissue (Female)	POLR3H	0.09	-0.01	lasso	6	-0.01	6.4e-01	-5.1	5.7	1.2e-08	-0.46	0.04	0.06	FALSE
13	GTEx	Testis	SREBF2	0.25	0.03	lasso	12	0.04	4.6e-03	4.7	5.5	3.5e-08	-0.41	0.62	0.04	FALSE
6	GTEx	Breast Mammary Tissue (Female)	DESI1	0.14	0.07	lasso	4	0.11	4.2e-04	-5.1	5.5	3.6e-08	-0.45	0.08	0.12	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	WBP2NL	0.04	0.03	lasso	8	0.03	5.6e-04	5.2	5.5	4.8e-08	-0.34	0.56	0.03	FALSE
4	GTEx	Breast Mammary Tissue (Male)	CYP2D6	0.34	-0.01	lasso	6	0.00	3.2e-01	5.0	-5.4	7.8e-08	0.36	0.11	0.10	FALSE
7	GTEx	Colon Sigmoid	DESI1	0.21	0.08	enet	6	0.11	1.2e-04	-5.1	5.3	1.1e-07	-0.47	0.40	0.05	FALSE
3	GTEx	Breast Mammary Tissue	POLR3H	0.15	0.02	enet	15	0.03	9.0e-03	5.1	5.3	1.2e-07	-0.22	0.18	0.10	FALSE
9	GTEx	Muscle Skeletal	POLR3H	0.17	0.12	lasso	3	0.11	8.0e-11	5.2	5.3	1.4e-07	-0.18	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	WBP2NL	0.28	0.25	enet	16	0.35	1.3e-43	5.2	5.2	2.1e-07	-0.35	1.00	0.00	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	NAGA	0.08	0.10	lasso	4	0.09	7.3e-12	5.2	5.2	2.3e-07	-0.30	1.00	0.00	FALSE
11	GTEx	Nerve Tibial	NAGA	0.12	0.09	lasso	6	0.08	1.8e-06	5.0	5.2	2.4e-07	-0.29	0.99	0.00	FALSE
10	GTEx	Nerve Tibial	CYP2D6	0.32	0.21	lasso	6	0.24	2.8e-17	4.8	-5.2	2.5e-07	0.39	1.00	0.00	FALSE