[Hub]/) : Traits : Trunk fat-free mass :

chr22:38,787,166-41,004,384

Best TWAS P=1.7e-09 · Best GWAS P=5.75e-10 conditioned to 0.00917

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous MGAT3 0.08 0.04 lasso 4 0.04 4.3e-04 -5.9 5.6 1.9e-08 0.04 0.02 0.98 FALSE
2 GTEx Artery Aorta APOBEC3G 0.40 0.40 lasso 3 0.39 6.3e-23 5.0 5.4 7.8e-08 0.04 0.56 0.44 FALSE
3 GTEx Esophagus Muscularis MGAT3 0.09 0.02 enet 15 0.02 1.3e-02 -2.3 5.2 1.6e-07 0.08 0.08 0.62 FALSE
4 GTEx Heart Atrial Appendage MGAT3 0.14 0.14 lasso 2 0.12 3.5e-06 -5.9 6.0 2.6e-09 0.02 0.01 0.99 TRUE
5 GTEx Nerve Tibial SYNGR1 0.26 0.18 enet 27 0.21 3.6e-15 -4.9 -5.8 7.0e-09 -0.04 0.06 0.94 FALSE
6 GTEx Pituitary APOBEC3G 0.34 0.04 enet 11 0.11 1.2e-03 4.8 5.7 1.2e-08 0.04 0.15 0.09 TRUE
7 GTEx Skin Sun Exposed Lower leg MGAT3 0.13 0.05 lasso 3 0.02 4.7e-03 -5.9 5.9 4.3e-09 0.01 0.01 0.98 FALSE
8 GTEx Skin Sun Exposed Lower leg APOBEC3G 0.10 0.09 lasso 3 0.06 7.5e-06 5.0 5.3 1.2e-07 0.05 0.56 0.41 FALSE
9 GTEx Vagina APOBEC3G 0.23 0.07 lasso 5 0.06 1.8e-02 4.8 5.4 8.0e-08 0.05 0.11 0.07 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma TNRC6B 0.02 0.01 blup 92 0.01 2.7e-03 -4.8 -5.2 1.6e-07 0.82 0.02 0.78 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ADSL 0.04 0.03 enet 6 0.03 1.6e-04 -6.1 -5.2 1.9e-07 0.86 0.00 0.94 FALSE
12 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma APOBEC3G 0.15 0.04 enet 17 0.09 9.7e-06 4.8 5.1 2.7e-07 0.03 0.00 0.83 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma ADSL 0.03 0.00 blup 33 0.01 8.9e-03 -5.9 -5.3 1.1e-07 0.82 0.01 0.60 FALSE
14 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ADSL 0.06 0.02 lasso 2 0.03 6.6e-03 -6.0 -6.0 2.2e-09 0.97 0.00 0.81 FALSE
15 The Cancer Genome Atlas Pancreatic Adenocarcinoma ADSL 0.09 0.03 lasso 3 0.01 7.7e-02 -6.1 -6.0 1.7e-09 0.91 0.00 0.76 TRUE