[Hub]/) : Traits : Trunk fat-free mass : ← →

chr2:197,560,575-201,571,143

Best TWAS P=3.76e-11 · Best GWAS P=1.99e-12 conditioned to 0.000417

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	GTEx	Skin Sun Exposed Lower leg	MARS2	0.04	0.05	enet	8	0.03	1.2e-03	-6.7	6.6	3.8e-11	-0.86	0.06	0.93	TRUE
5	GTEx	Brain Hippocampus	FTCDNL1	0.35	0.24	enet	24	0.26	9.0e-07	-4.4	-6.5	8.5e-11	-0.10	0.26	0.33	TRUE
6	GTEx	Brain Nucleus accumbens basal ganglia	C2orf47	0.25	0.01	lasso	3	0.00	2.8e-01	5.3	-5.8	6.8e-09	0.04	0.05	0.52	TRUE
9	GTEx	Lung	RFTN2	0.06	0.08	lasso	8	0.06	2.7e-05	-6.6	-6.6	5.1e-11	0.86	0.06	0.94	FALSE
15	GTEx	Thyroid	PLCL1	0.04	0.01	lasso	4	0.00	2.6e-01	-6.5	-6.5	6.2e-11	0.76	0.15	0.62	FALSE
11	GTEx	Spleen	RFTN2	0.11	0.03	enet	26	0.05	2.4e-02	-6.6	-6.5	6.4e-11	0.84	0.06	0.54	FALSE
12	GTEx	Spleen	MARS2	0.12	0.04	lasso	5	0.00	3.4e-01	-6.6	6.3	2.2e-10	-0.82	0.06	0.44	FALSE
23	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RFTN2	0.05	0.01	blup	61	0.02	3.1e-02	-5.1	-6.3	2.4e-10	0.70	0.04	0.40	FALSE
17	GTEx	Whole Blood	PLCL1	0.08	0.08	enet	15	0.05	4.1e-05	-6.0	-6.3	3.6e-10	0.92	0.17	0.83	FALSE
14	GTEx	Thyroid	SF3B1	0.04	0.02	enet	14	0.02	2.0e-02	-5.1	-6.2	5.8e-10	0.72	0.09	0.84	FALSE
7	GTEx	Breast Mammary Tissue	SF3B1	0.06	0.06	lasso	4	0.03	6.6e-03	-5.1	-5.9	3.3e-09	0.61	0.17	0.67	FALSE
8	GTEx	Breast Mammary Tissue (Female)	SF3B1	0.05	-0.01	lasso	3	-0.01	8.1e-01	-5.1	-5.8	8.7e-09	0.65	0.05	0.10	FALSE
21	The Cancer Genome Atlas	Lung Adenocarcinoma	C2orf60	0.03	0.03	blup	44	0.03	1.8e-04	-5.3	5.7	1.6e-08	-0.05	0.01	0.97	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	TYW5	0.11	0.12	lasso	5	0.11	5.5e-14	-5.3	5.6	1.8e-08	-0.04	0.02	0.98	FALSE
2	CommonMind	Brain Pre-frontal Cortex	TYW5	0.08	0.14	lasso	8	0.13	2.2e-15	-5.3	5.6	2.3e-08	-0.05	0.02	0.98	FALSE
3	GTEx	Adipose Subcutaneous	RFTN2	0.14	0.10	enet	11	0.13	5.3e-11	-6.1	-5.5	3.0e-08	0.86	0.17	0.82	FALSE
20	YFS	Blood	PLCL1	0.10	0.10	lasso	9	0.14	1.5e-43	-6.2	-5.4	5.7e-08	0.83	0.50	0.50	FALSE
22	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C2orf60	0.04	0.05	lasso	5	0.03	2.1e-03	-5.4	5.4	5.8e-08	-0.04	0.01	0.91	FALSE
4	GTEx	Brain Caudate basal ganglia	TYW5	0.23	0.11	lasso	3	0.11	5.4e-04	-4.5	5.4	6.6e-08	-0.03	0.04	0.55	FALSE
16	GTEx	Thyroid	RFTN2	0.04	0.01	enet	11	0.01	9.5e-02	-6.6	-5.4	8.4e-08	0.80	0.07	0.80	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	C2orf69	0.07	0.04	enet	13	0.06	3.6e-08	-5.1	5.2	1.7e-07	-0.05	0.05	0.95	FALSE
13	GTEx	Testis	SF3B1	0.10	0.07	enet	17	0.08	2.6e-04	-5.1	-5.2	2.2e-07	0.55	0.45	0.50	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SF3B1	0.06	0.07	enet	10	0.07	2.5e-09	-5.1	-5.1	2.8e-07	0.49	0.99	0.01	FALSE