[Hub]/) : Traits : Trunk fat-free mass :

chr3:9,283,299-11,999,795

Best TWAS P=8.76e-13 · Best GWAS P=8.55e-16 conditioned to 1.46e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CRELD1 0.46 0.16 enet 51 0.27 2.2e-22 -6.1 -6.8 8.5e-12 0.07 0.00 1.00 FALSE
2 GTEx Adipose Visceral Omentum CRELD1 0.19 0.12 lasso 4 0.10 4.1e-06 -6.1 -5.8 5.5e-09 -0.02 0.00 0.99 FALSE
3 GTEx Artery Aorta CRELD1 0.30 0.07 lasso 7 0.12 2.4e-07 -6.1 -6.1 8.6e-10 0.03 0.00 1.00 FALSE
4 GTEx Artery Aorta RP11-1020A11.1 0.15 0.01 lasso 3 0.00 4.0e-01 -6.1 -6.8 9.7e-12 -0.03 0.02 0.75 FALSE
5 GTEx Artery Tibial CRELD1 0.43 0.15 enet 41 0.21 1.1e-16 -6.1 -6.1 9.0e-10 0.08 0.00 1.00 FALSE
6 GTEx Breast Mammary Tissue CRELD1 0.25 0.19 lasso 6 0.18 2.2e-09 -6.1 -5.9 2.8e-09 -0.02 0.00 1.00 FALSE
7 GTEx Cells Transformed fibroblasts CRELD1 0.39 0.19 enet 39 0.28 4.5e-21 -6.1 -7.1 8.8e-13 0.04 0.00 1.00 TRUE
8 GTEx Cells Transformed fibroblasts HRH1 0.20 0.00 lasso 3 0.01 1.1e-01 8.0 -6.5 7.0e-11 -0.77 0.00 0.95 TRUE
9 GTEx Cells Transformed fibroblasts RP11-1020A11.1 0.20 0.10 enet 67 0.09 1.9e-07 -6.1 -6.2 7.5e-10 0.01 0.00 1.00 FALSE
10 GTEx Esophagus Muscularis CRELD1 0.21 0.10 lasso 1 0.08 1.7e-05 -6.1 -6.1 8.8e-10 -0.02 0.00 1.00 FALSE
11 GTEx Nerve Tibial CRELD1 0.17 0.05 enet 9 0.13 2.0e-09 -6.1 -5.1 2.7e-07 0.04 0.00 1.00 FALSE
12 GTEx Skin Sun Exposed Lower leg CRELD1 0.29 0.15 enet 36 0.23 8.2e-19 -6.1 -6.2 4.2e-10 0.04 0.00 1.00 FALSE
13 GTEx Testis CRELD1 0.22 0.22 lasso 8 0.26 1.1e-11 4.6 -6.6 5.5e-11 0.00 0.14 0.86 FALSE
14 METSIM Adipose BRK1 0.04 0.02 bslmm 559 0.01 8.9e-03 4.2 -5.3 1.0e-07 -0.04 0.20 0.59 FALSE
15 METSIM Adipose CRELD1 0.23 0.16 bslmm 480 0.21 3.1e-30 -6.1 -5.5 3.5e-08 0.07 0.00 1.00 FALSE
16 ROSMAP Brain Pre-frontal Cortex AC022007.5 0.05 0.02 blup 515 0.03 2.8e-04 5.6 5.2 1.6e-07 0.02 0.07 0.93 FALSE
17 YFS Blood FANCD2 0.04 0.04 lasso 1 0.04 7.7e-13 5.7 -5.7 1.5e-08 -0.06 0.04 0.96 TRUE
18 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CRELD1 0.03 0.00 blup 49 0.01 1.4e-02 -2.4 -5.2 2.1e-07 0.05 0.01 0.11 FALSE
19 The Cancer Genome Atlas Prostate Adenocarcinoma CIDECP 0.04 0.02 blup 33 0.03 3.8e-04 4.6 5.2 1.9e-07 0.00 0.05 0.89 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma LOC401052 0.06 0.07 enet 6 0.06 3.5e-07 5.7 -5.6 1.6e-08 -0.05 0.01 0.99 FALSE
21 The Cancer Genome Atlas Soft Tissue Sarcoma CRELD1 0.12 0.01 enet 22 0.04 1.4e-03 -2.1 -5.4 8.7e-08 0.04 0.02 0.19 FALSE