TWAS hub - CRELD1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.4620	0.0740	4.2e-11	0.157	NA	0.273	NA	0.191	7.3e-13	NA	2.2e-22	NA	1.7e-15
2	GTEx	Adipose Visceral Omentum	0.1920	0.0680	5.7e-04	0.115	NA	0.093	NA	0.105	1.5e-06	NA	1.5e-05	NA	4.1e-06
3	GTEx	Artery Aorta	0.3000	0.0740	1.0e-05	0.072	NA	0.116	NA	0.124	8.6e-05	NA	6.0e-07	NA	2.5e-07
4	GTEx	Artery Tibial	0.4252	0.0867	7.1e-08	0.152	NA	0.214	NA	0.184	5.8e-12	NA	1.1e-16	NA	2.3e-14
5	GTEx	Breast Mammary Tissue	0.2490	0.0710	1.9e-04	0.188	NA	0.143	NA	0.176	5.8e-10	NA	8.2e-08	NA	2.2e-09
6	GTEx	Cells Transformed fibroblasts	0.3940	0.0750	7.1e-11	0.191	NA	0.279	NA	0.241	2.7e-14	NA	4.5e-21	NA	4.7e-18
7	GTEx	Esophagus Mucosa	0.1390	0.0570	4.5e-03	0.058	NA	0.111	NA	0.105	9.8e-05	NA	7.7e-08	NA	1.7e-07
8	GTEx	Esophagus Muscularis	0.2100	0.0640	2.1e-04	0.103	NA	0.043	NA	0.078	8.6e-07	NA	1.2e-03	NA	1.7e-05
9	GTEx	Nerve Tibial	0.1659	0.0599	1.1e-03	0.045	NA	0.129	NA	0.122	3.6e-04	NA	2.0e-09	NA	5.9e-09
10	GTEx	Skin Not Sun Exposed Suprapubic	0.2850	0.0650	1.6e-07	0.067	NA	0.133	NA	-0.003	1.6e-04	NA	9.7e-08	NA	4.9e-01
11	GTEx	Skin Sun Exposed Lower leg	0.2880	0.0620	8.0e-09	0.146	NA	0.229	NA	0.202	4.0e-12	NA	8.2e-19	NA	1.3e-16
12	GTEx	Testis	0.2160	0.0590	3.4e-07	0.222	NA	0.252	NA	0.255	3.4e-10	NA	1.5e-11	NA	1.1e-11
13	METSIM	Adipose	0.2303	0.0495	3.1e-15	0.157	0.132	0.180	0.207	0.176	7.5e-23	3.4e-19	3.0e-26	3.1e-30	1.2e-25
14	ROSMAP	Brain Pre-frontal Cortex	0.1541	0.0376	3.9e-16	0.139	0.144	0.141	0.149	0.141	2.1e-17	4.3e-18	9.4e-18	1.0e-18	1.2e-17
15	YFS	Blood	0.1228	0.0261	0.0e+00	0.092	0.107	0.115	0.118	0.117	2.0e-28	3.7e-33	1.6e-35	2.3e-36	4.0e-36
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.0458	0.0319	1.6e-03	0.003	0.020	0.028	NA	0.010	1.2e-01	2.1e-03	3.5e-04	NA	2.1e-02
17	TCGA	Brain Lower Grade Glioma	0.0481	0.0273	1.2e-03	0.033	0.028	0.025	NA	0.025	1.0e-04	3.1e-04	6.4e-04	NA	6.4e-04
18	TCGA	Lung Squamous Cell Carcinoma	0.0308	0.0201	7.4e-03	-0.001	0.012	-0.002	NA	-0.002	4.8e-01	1.4e-02	5.7e-01	NA	7.7e-01
19	TCGA	Soft Tissue Sarcoma	0.1170	0.0650	5.8e-04	0.013	0.035	0.043	NA	0.029	5.3e-02	3.5e-03	1.4e-03	NA	7.9e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Comparative height size at age 10	7.0	38.7	69.6	-8.3	-7.0	-7.3	-6.8	-6.7	-8.2	-5.9	-6.8	-6.5	-6.6	-7.7	-6.5	-6.5	1.4	-0.4	-4.8	2.6	-5.3	-6.1
Height	6.3	121.3	216.1	-14.7	-13.0	-12.6	-13.4	-12.1	-14.2	-11.4	-12.1	-11.9	-10.7	-13.9	-10.1	-12.6	0.7	-2.6	-8.3	2.6	-9.7	-8.4
Standing height	5.2	51.3	97.0	-9.8	-7.9	-8.2	-8.3	-7.2	-9.4	-7.0	-7.2	-7.5	-8.0	-9.4	-6.5	-7.9	1.0	-0.8	-5.8	1.9	-6.8	-6.3
Trunk fat-free mass	5.1	29.1	51.1	-6.8	-5.8	-6.1	-6.1	-5.9	-7.1	-4.9	-6.1	-5.1	-5.1	-6.2	-6.6	-5.5	2.7	0.7	-3.8	2.7	-5.2	-5.4
Trunk predicted mass	5.1	29.1	50.8	-6.8	-5.8	-6.1	-6.1	-5.9	-7.1	-5.0	-6.1	-5.2	-5.1	-6.3	-6.5	-5.5	2.5	0.6	-3.8	2.5	-5.2	-5.3
Whole body water mass	5.1	29.1	51.3	-6.6	-6.1	-6.1	-5.8	-6.1	-7.1	-4.7	-6.4	-4.9	-4.6	-5.9	-7.2	-5.4	3.3	1.1	-3.4	3.4	-5.1	-5.4
Whole body fat-free mass	4.9	28.0	49.4	-6.5	-5.9	-5.9	-5.7	-6.0	-7.0	-4.5	-6.2	-4.8	-4.7	-5.8	-7.0	-5.3	3.2	1.1	-3.3	3.3	-5.0	-5.4
Sitting height	4.7	33.4	64.5	-7.8	-6.0	-6.5	-6.4	-5.2	-8.0	-5.3	-5.2	-5.9	-7.6	-7.5	-5.5	-6.0	1.1	0.3	-5.0	2.3	-5.8	-5.6
Medication: Ventolin 100micrograms inhaler	4.7	6.0	12.5	2.8	2.7	2.7	3.4	2.3	3.5	2.8	2.2	3.1	2.7	2.6	0.7	2.8	1.3	1.3	1.8	1.4	1.7	2.4
Basal metabolic rate	4.7	25.9	50.7	-6.1	-5.9	-5.7	-5.4	-5.9	-6.6	-4.2	-6.1	-4.5	-4.1	-5.3	-7.1	-5.0	3.4	1.3	-2.9	3.6	-4.6	-5.1
Leg fat-free mass (right)	4.6	24.7	52.2	-6.0	-5.8	-5.5	-5.0	-5.8	-6.5	-3.9	-6.0	-4.3	-3.7	-5.2	-7.2	-4.9	3.6	1.4	-2.6	3.9	-4.5	-4.9
Leg predicted mass (right)	4.6	24.8	52.6	-6.0	-5.8	-5.5	-5.1	-5.9	-6.5	-3.9	-6.1	-4.3	-3.7	-5.2	-7.2	-4.9	3.6	1.4	-2.6	4.0	-4.5	-4.9
Leg fat-free mass (left)	4.5	23.7	50.5	-5.7	-5.8	-5.4	-5.0	-5.8	-6.3	-3.9	-6.0	-4.2	-3.6	-5.0	-7.1	-4.8	3.6	1.4	-2.4	3.8	-4.4	-4.8
Leg predicted mass (left)	4.4	23.5	49.7	-5.7	-5.8	-5.3	-5.0	-5.8	-6.2	-3.9	-6.0	-4.2	-3.6	-5.0	-7.0	-4.8	3.5	1.4	-2.5	3.8	-4.4	-4.8
Birth weight	4.4	9.4	18.4	-3.8	-3.1	-3.6	-3.4	-3.0	-4.3	-3.1	-2.9	-3.4	-3.5	-3.6	-3.2	-2.8	0.8	0.1	-2.7	0.7	-3.4	-3.4
Arm fat-free mass (left)	4.4	22.5	44.9	-5.6	-5.3	-5.2	-5.0	-5.3	-6.2	-3.8	-5.6	-4.1	-3.9	-4.9	-6.7	-4.9	3.3	1.3	-2.8	3.5	-4.4	-5.1
Hip circumference	4.3	18.7	41.7	-4.9	-5.9	-4.7	-4.7	-5.4	-5.7	-3.3	-5.7	-3.7	-2.9	-4.0	-6.5	-4.4	2.9	0.9	-1.4	3.8	-3.0	-3.6
Arm predicted mass (left)	4.3	21.8	45.8	-5.5	-5.2	-5.2	-4.8	-5.2	-6.1	-3.6	-5.5	-4.0	-3.8	-4.7	-6.8	-4.8	3.6	1.6	-2.8	3.6	-4.4	-5.0
Arm fat-free mass (right)	4.2	21.7	41.7	-5.4	-5.1	-5.3	-4.9	-5.1	-5.8	-3.9	-5.3	-4.2	-3.8	-4.8	-6.5	-4.6	3.3	1.4	-3.3	3.1	-4.9	-5.1
Arm predicted mass (right)	4.2	21.6	40.8	-5.4	-5.1	-5.2	-4.9	-5.1	-5.8	-3.9	-5.3	-4.1	-3.9	-4.9	-6.4	-4.6	3.4	1.4	-3.1	3.1	-4.8	-5.1
Weight	3.6	17.7	46.0	-4.7	-5.4	-4.5	-4.0	-5.3	-5.2	-3.0	-5.6	-3.3	-2.4	-3.7	-6.8	-4.0	3.7	1.7	-1.4	4.2	-3.0	-4.0
Illness, injury, bereavement, stress in last 2 years	2.9	3.5	9.8	-2.6	-1.9	-1.6	-3.1	-1.8	-2.7	-1.8	-1.7	-2.0	-2.3	-2.0	-0.8	-2.6	-0.7	-2.1	-0.6	-0.3	-0.5	-0.6
Pain all over the body in last month	2.7	2.9	6.5	-1.3	-2.3	-2.5	-1.6	-2.3	-1.9	-2.0	-2.4	-1.8	-1.6	-1.2	-1.8	-1.6	0.5	-0.1	-1.8	1.3	-0.8	-1.3
Number of operations (self-reported)	2.7	4.0	9.7	-1.7	-2.8	-2.8	-1.5	-2.8	-2.6	-1.8	-3.1	-2.2	1.0	-0.8	-3.0	-2.0	1.4	-0.1	-0.3	1.2	-0.9	-1.4
Pack years adult smoking proportion	2.5	3.8	7.9	2.0	1.1	2.1	2.8	1.1	2.1	2.2	0.8	2.5	2.7	1.9	-0.1	1.6	1.1	1.0	2.6	2.0	2.2	2.6
Pack years of smoking	2.5	3.7	8.4	1.9	1.0	2.1	2.6	1.0	2.1	2.2	0.8	2.4	2.9	1.9	-0.2	1.5	1.2	0.9	2.5	2.1	2.2	2.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.3	2.8	9.5	1.7	1.3	1.3	1.5	1.6	1.9	0.1	1.6	0.5	1.2	1.0	3.1	1.7	-2.8	-1.4	0.6	-2.7	1.2	1.4
Waist Hip Ratio (WHR)	2.2	10.1	19.5	3.7	3.2	3.5	4.4	3.5	4.4	3.5	3.5	3.8	2.4	3.6	2.4	3.5	0.5	1.0	3.2	0.3	3.4	2.4
Fasting Glucose	2.1	2.5	5.5	1.7	2.3	2.2	1.5	2.0	1.6	1.9	1.9	2.2	1.4	1.7	1.3	1.1	0.4	0.6	1.1	0.5	1.5	1.0
Lung FEV1/FVC ratio	2.1	10.7	24.4	4.9	3.0	4.1	3.5	3.6	4.6	2.3	3.7	3.3	2.3	4.2	4.0	3.8	-1.5	-0.4	2.4	-2.9	2.2	1.7
Medication: Co-codamol	2.1	2.4	7.4	-1.4	-0.8	-1.3	-0.6	-1.6	-1.0	-0.7	-1.4	-0.6	-1.7	-1.2	-2.7	-0.5	2.3	1.7	-1.7	2.3	-1.6	-2.1
Diabetes (father)	2.0	2.5	5.1	1.5	1.5	2.2	1.7	1.8	2.3	1.8	1.7	2.1	1.1	1.5	1.8	1.2	-0.5	-0.2	1.7	-0.7	1.8	1.1
Tinnitus: Yes, but not now, but have in the past	2.0	2.1	4.7	2.1	1.9	1.3	1.9	1.1	1.3	1.6	1.0	1.6	1.9	2.2	-0.4	1.7	1.5	1.0	0.6	1.1	0.6	1.1
Medication: Aspirin	2.0	2.6	12.6	-0.6	-1.4	-1.1	-0.4	-1.7	-1.0	0.1	-1.9	-0.0	0.4	-0.2	-3.0	-0.3	3.5	2.3	-0.4	3.0	-0.3	-1.5
Alzheimer’s Disease (in father)	1.9	2.0	4.9	-1.5	-0.9	-2.2	-1.1	-1.9	-0.9	-2.1	-1.8	-1.9	-0.5	-1.8	-0.7	-0.9	-0.2	-1.4	-2.0	-0.3	-1.2	-0.7
Heel T-Score	1.9	15.1	23.8	4.3	4.3	4.8	3.9	4.8	4.9	4.4	4.8	4.2	3.6	4.4	4.2	3.4	-0.8	0.5	3.6	-1.9	3.9	3.3
Eye problems/disorders: Diabetes related eye disease	1.9	2.0	5.9	-1.6	-1.3	-1.7	-2.4	-1.5	-2.2	-1.3	-1.6	-1.3	-0.5	-1.3	-1.7	-1.9	0.8	-0.5	-0.2	0.7	-1.3	-0.9
Forced vital capacity (FVC)	1.9	7.3	16.7	-4.0	-2.2	-2.7	-3.9	-2.6	-3.6	-2.3	-2.5	-2.6	-3.8	-4.1	-2.0	-2.9	-0.2	0.4	-2.1	0.1	-2.3	-1.9
Hearing aid user	1.9	2.1	4.1	-1.4	-2.0	-1.7	-1.6	-2.0	-1.8	-1.9	-1.9	-1.9	-0.7	-1.4	-1.0	-1.5	-0.3	-1.1	-1.4	0.0	-0.6	-1.1
Alzheimer’s Disease (including proxy)	1.8	2.6	7.7	-1.9	-1.5	-2.8	-1.1	-2.3	-1.1	-2.2	-2.3	-2.7	-0.2	-1.9	-0.4	-1.1	-0.8	-1.0	-0.6	-1.4	-0.7	-1.0
Ulcerative Colitis	1.8	2.6	11.2	-0.9	0.7	0.4	-0.2	0.7	0.4	-0.8	0.7	-0.6	-0.8	-1.5	3.1	-0.4	-3.3	-3.0	0.7	-2.9	1.3	1.4
Medication: Omeprazole	1.8	2.1	4.5	1.6	0.7	1.8	1.5	0.9	1.6	1.6	0.9	1.7	2.0	2.1	-0.2	1.5	1.8	1.3	1.1	1.4	0.5	1.6
Had major operations	1.8	2.2	5.4	-1.6	-1.8	-1.8	-1.4	-1.6	-2.3	-1.3	-1.8	-1.6	0.9	-1.0	-2.2	-1.5	1.3	0.2	-0.3	1.3	-1.3	-0.7
Heart disease (mother)	1.7	2.1	4.5	-1.7	-0.8	-1.3	-1.1	-1.1	-1.7	-0.4	-1.1	-0.7	-1.4	-1.7	-2.1	-2.0	1.0	1.4	-1.7	1.6	-1.7	-1.2
Deep venous thrombosis (DVT) (self-reported)	1.7	2.2	4.8	2.0	1.5	1.8	1.7	1.6	1.6	1.6	1.5	2.1	1.8	2.2	0.1	1.4	0.7	1.5	0.6	0.9	-0.0	0.7
Trunk fat mass	1.6	7.0	24.0	-2.2	-4.0	-2.6	-1.8	-3.4	-2.8	-1.4	-3.6	-1.6	-0.8	-1.4	-4.9	-1.9	3.0	1.6	-0.5	3.7	-1.6	-2.7
Medication: Simvastatin	1.6	2.4	11.8	1.7	1.4	1.3	1.4	0.4	1.8	1.7	0.2	1.7	3.4	2.1	-0.4	1.2	1.7	1.4	1.1	0.9	1.2	0.9
Birth weight of first child	1.6	2.9	6.0	-1.5	-1.9	-2.1	-1.8	-2.0	-1.8	-2.4	-2.0	-2.3	-1.0	-1.7	-0.8	-1.4	-1.2	-1.8	-1.4	-0.8	-1.4	-1.4
Mouth/teeth dental problems: Bleeding gums	1.6	2.1	5.3	-1.5	-1.2	-1.4	-2.3	-1.4	-2.0	-0.7	-1.4	-0.7	-1.9	-1.8	-1.9	-1.9	0.6	0.4	-0.2	1.4	-0.8	-2.0
Wheeze or whistling in the chest in last year	1.6	2.8	5.1	1.8	1.3	1.4	2.2	1.5	1.6	2.2	1.3	1.9	1.6	2.0	-0.3	2.3	1.9	1.6	1.9	1.8	1.3	0.4
Whole body fat mass	1.6	6.6	23.1	-2.1	-3.7	-2.5	-1.9	-3.5	-2.7	-1.4	-3.7	-1.5	-0.4	-1.4	-4.8	-2.0	2.9	1.4	-0.1	3.7	-1.2	-2.1
Family relationship satisfaction	1.6	1.9	5.0	2.2	1.3	1.4	1.7	1.5	1.8	1.3	1.4	1.4	1.7	1.9	0.8	1.7	0.2	0.7	1.6	-0.2	0.0	1.0
Long-standing illness, disability or infirmity	1.6	2.4	12.8	0.5	-0.6	-1.0	-0.1	-1.0	-0.0	0.7	-1.2	0.1	0.7	0.8	-2.9	0.8	3.6	2.6	-0.2	3.4	-0.0	-0.8
Diabetes diagnosed by doctor	1.6	2.7	6.1	-1.4	-1.2	-1.7	-1.1	-1.9	-1.6	-1.9	-2.0	-1.6	-0.0	-1.0	-2.5	-1.4	1.9	0.3	-1.8	1.4	-2.1	-2.2
Medication: Aspirin	1.6	2.0	9.9	-0.6	-1.3	-0.9	0.0	-1.6	-0.8	0.2	-1.7	0.1	0.2	-0.3	-2.6	-0.1	3.2	2.1	-0.4	2.5	-0.2	-1.4
Supplements: Fish oil (including cod liver oil)	1.6	2.0	5.9	2.1	1.5	2.0	1.7	1.6	1.5	1.7	1.6	2.0	1.2	2.4	0.7	0.6	0.7	1.0	0.4	0.2	0.4	0.6
Angina	1.5	2.0	12.2	-0.6	-1.3	-0.5	0.2	-1.1	-0.8	0.6	-1.3	0.5	1.4	-0.3	-2.4	-0.4	2.6	1.4	1.2	3.5	0.3	0.5
Alcohol usually taken with meals	1.5	2.5	6.9	-1.6	-0.3	-1.2	-1.9	-0.3	-2.4	-1.9	-0.3	-1.6	-2.4	-1.9	-0.5	-0.9	0.1	-0.4	-2.1	-0.5	-2.6	-2.2
Financial difficulties in last 2 years	1.5	2.0	3.8	1.5	2.0	1.4	1.4	1.4	1.4	1.6	1.3	1.4	1.3	1.1	1.8	0.4	-1.3	-0.6	1.2	-0.8	1.9	1.7
Angina (self-reported)	1.5	1.9	11.3	-0.6	-1.4	-0.5	0.1	-1.0	-0.8	0.7	-1.3	0.4	1.4	-0.3	-2.4	-0.6	2.6	1.3	1.3	3.4	0.3	0.5
Knee pain experienced in last month	1.5	2.4	8.6	-1.2	-1.6	-1.2	-1.0	-1.6	-1.2	-0.2	-1.8	-0.4	-0.6	-1.2	-2.9	-0.3	2.3	1.9	0.2	2.6	-0.9	-2.0
Average weekly beer plus cider intake	1.5	2.2	6.2	1.6	1.5	1.6	1.8	1.0	1.6	1.6	1.1	1.5	1.2	2.0	1.2	1.1	-0.3	-0.7	2.2	-0.2	2.5	1.5
Heart disease (siblings)	1.5	1.9	4.8	0.6	2.0	1.8	1.0	1.5	0.6	2.0	1.4	2.0	1.4	1.1	-0.7	1.1	1.7	1.2	1.0	2.2	0.3	0.1
Leg fat mass (left)	1.5	5.8	22.3	-1.7	-3.1	-2.3	-1.6	-3.1	-2.5	-1.2	-3.4	-1.3	-0.3	-0.9	-4.7	-1.9	3.1	1.6	-0.1	3.7	-1.3	-2.4
Fluid intelligence score	1.4	2.8	6.1	-2.3	-1.6	-1.8	-2.1	-1.2	-2.2	-1.8	-1.3	-1.8	-2.2	-2.5	-0.8	-1.4	-0.3	-0.3	-0.9	-1.0	-2.0	-2.2
Blood clot in the leg (DVT)	1.4	1.9	4.2	1.8	1.3	1.7	1.5	1.4	1.4	1.6	1.3	2.0	1.6	2.1	-0.1	1.2	0.8	1.5	0.7	1.1	-0.0	0.7
Migraine (self-reported)	1.4	1.7	4.7	-2.0	-1.2	-1.7	-0.8	-1.3	-1.9	-0.4	-1.4	-1.1	-1.0	-1.2	-1.9	-1.3	1.1	0.4	-0.2	0.7	-0.6	-2.2
Loneliness, isolation	1.4	1.9	4.8	-1.6	-1.8	-1.5	-1.6	-2.0	-1.3	-1.0	-2.2	-1.8	0.0	-1.6	-0.6	-2.0	-0.0	-0.7	0.5	-0.3	1.1	1.1
Arm fat mass (left)	1.4	5.8	23.2	-1.6	-3.3	-2.2	-1.5	-3.2	-2.4	-1.1	-3.5	-1.1	-0.0	-1.0	-4.8	-1.5	3.2	1.7	0.2	3.7	-1.0	-2.0
Pain type(s) experienced in last month: Hip pain	1.4	1.8	3.5	-1.5	-1.6	-1.8	-1.4	-1.6	-1.6	-1.4	-1.8	-1.6	-0.6	-1.0	-1.9	0.0	0.5	0.6	-0.9	0.7	-1.0	-1.7
Alzheimer’s Disease (in mother)	1.3	1.5	4.3	-0.8	-1.9	-1.8	-0.7	-1.8	-0.7	-1.6	-2.0	-2.1	0.4	-0.9	-0.3	-0.7	-1.0	-0.7	0.9	-1.1	0.2	-0.3
Ulcerative Colitis (UC)	1.3	2.4	9.3	-0.8	1.2	0.5	0.1	1.0	0.2	-0.5	1.2	-0.2	-1.7	-1.2	3.0	-1.0	-2.7	-3.0	0.6	-2.2	1.5	1.3
Bipolar Disorder (2011)	1.3	1.2	6.1	1.3	-0.1	0.0	0.7	0.5	0.8	0.4	0.0	0.0	1.4	0.3	1.4	1.1	-2.5	-0.9	0.9	-1.6	1.9	1.2
Primary Biliary Cirrhosis	1.3	1.8	4.3	1.1	2.0	1.7	1.9	2.1	1.5	1.4	2.0	1.8	0.3	1.2	0.7	1.2	0.2	1.4	-0.7	-0.1	-0.6	-0.8
Allergy or Eczema	1.3	3.3	8.2	1.4	1.9	2.0	1.9	2.2	1.6	2.2	2.1	1.7	2.9	1.9	1.5	1.8	0.1	0.4	2.6	-0.4	1.7	1.7
Impedance of leg (right)	1.3	6.4	23.8	2.3	2.8	2.5	1.9	3.7	2.8	1.4	4.0	1.6	-0.2	1.7	4.9	1.8	-3.2	-1.4	0.2	-2.9	1.5	1.8
Qualifications: CSEs or equivalent	1.3	1.8	4.4	1.4	1.6	1.1	2.0	1.8	1.4	1.6	1.6	1.2	0.9	1.5	1.2	2.1	0.4	1.0	1.0	0.1	1.1	0.5
Waist circumference	1.3	4.9	19.7	-1.6	-3.2	-1.9	-1.1	-3.1	-1.8	-0.7	-3.4	-0.8	0.4	-0.8	-4.4	-1.5	3.1	1.5	0.8	3.7	-0.5	-1.3
Alcohol intake versus 10 years previously	1.3	1.9	8.1	0.7	-0.6	-0.3	0.1	-0.9	0.1	1.0	-1.1	0.5	1.8	1.2	-2.4	-0.0	2.4	2.9	-0.2	2.7	0.5	-0.3
Asthma	1.3	2.6	6.1	1.4	2.2	1.3	2.1	1.8	2.5	1.6	1.6	1.1	2.3	1.8	1.4	1.2	0.4	0.5	1.4	-0.1	1.5	1.9
Arm fat mass (right)	1.3	5.5	21.2	-1.7	-3.3	-2.2	-1.5	-3.2	-2.5	-1.1	-3.5	-1.2	-0.2	-1.0	-4.6	-1.7	2.9	1.5	0.4	3.6	-0.7	-1.9
Ever highly irritable/argumentative for 2 days	1.3	1.6	3.5	1.8	1.9	1.2	1.2	1.6	1.1	1.9	1.7	1.5	0.7	1.9	1.0	0.6	0.3	0.2	0.8	-0.2	1.0	1.0
Forced vital capacity (FVC), Best measure	1.3	4.7	11.7	-3.2	-1.6	-2.3	-3.0	-2.2	-2.6	-1.7	-2.1	-2.0	-3.2	-3.4	-1.9	-2.1	0.1	0.6	-1.8	0.3	-1.7	-1.3
Leg fat mass (right)	1.3	5.0	19.6	-1.4	-3.0	-2.0	-1.5	-2.9	-2.2	-1.0	-3.1	-1.1	-0.2	-0.7	-4.4	-1.7	3.0	1.5	0.1	3.6	-1.2	-2.1
Mineral and other dietary supplements	1.3	1.8	3.8	-1.7	-1.6	-1.9	-1.0	-1.7	-1.2	-1.5	-1.6	-1.7	-1.8	-1.9	-1.2	-0.3	-0.0	-0.3	-0.7	0.4	-0.7	-1.3
Breast cancer (self-reported)	1.3	1.5	5.7	-1.1	-0.7	-0.3	-1.4	-0.4	-1.1	-1.1	-0.4	-0.9	-1.7	-1.9	0.9	-1.4	-2.4	-1.9	-0.6	-1.7	-0.3	-0.2
Ovarian Cancer	1.2	1.6	6.3	-1.3	-2.0	-0.7	-1.8	-0.5	-1.1	-1.4	-0.6	-0.9	-2.5	-1.8	0.4	-1.0	-1.6	-0.4	-1.3	-0.6	-0.6	-0.6
Type 2 Diabetes (T2D) (2018)	1.2	2.2	5.8	-0.9	-0.6	-1.4	-0.6	-1.5	-0.9	-1.8	-1.4	-1.1	-0.5	-0.7	-2.2	-0.7	2.2	0.8	-1.9	1.5	-2.4	-2.2
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	4.0	-0.3	-1.8	-1.6	-1.3	-1.9	-1.4	-1.6	-2.0	-1.5	-0.3	-0.6	-1.6	-1.3	0.5	-0.6	-0.4	1.0	-0.8	-0.2
Impedance of leg (left)	1.2	5.8	21.8	2.0	2.7	2.4	2.0	3.5	2.5	1.4	3.8	1.5	-0.3	1.6	4.7	1.6	-3.3	-1.6	0.0	-2.6	1.5	1.5
Medication: Amlodipine	1.2	1.7	4.4	1.5	1.6	1.3	1.4	0.9	1.1	1.8	0.7	1.7	1.5	1.3	0.2	0.7	0.8	0.4	1.4	1.2	1.7	2.1
Neck or shoulder pain in last month	1.2	1.7	5.2	-0.7	-1.2	-2.0	-0.3	-1.4	-1.7	-1.1	-1.6	-1.5	-0.1	-0.6	-2.1	-0.2	1.1	0.5	-0.5	1.3	-1.1	-2.3
Asthma (self-reported)	1.2	2.4	6.0	1.2	2.0	1.2	1.9	1.5	2.4	1.5	1.4	1.0	2.4	1.7	1.3	1.1	0.3	0.4	1.4	-0.1	1.7	2.1
Mother’s age at death	1.2	1.5	3.8	-1.2	-1.5	-1.3	-0.9	-1.2	-0.6	-1.9	-1.1	-1.4	-1.6	-1.6	0.1	-0.5	-1.2	-0.5	-2.0	-0.6	-0.9	-1.5
Ever depressed for a whole week	1.2	1.5	6.5	2.6	0.3	0.9	1.0	0.5	2.1	0.9	0.5	1.1	1.9	2.1	0.5	1.6	0.5	1.1	0.2	-0.1	0.6	1.1
Supplements: Calcium	1.2	1.3	3.0	0.6	1.5	1.2	1.2	1.7	1.0	0.9	1.7	0.8	0.8	0.7	1.6	0.5	-1.3	-0.8	1.5	-0.9	0.8	1.3
Intelligence (Savage-Jansen 2018)	1.1	3.4	8.4	-2.7	-1.6	-2.0	-2.3	-1.3	-2.9	-1.9	-1.3	-2.0	-2.8	-2.9	-0.7	-1.1	-0.8	-0.3	-1.3	-0.5	-2.1	-1.3
Schizophrenia vs Biploar Disorder	1.1	1.5	3.4	-1.2	-0.3	-1.3	-1.6	-0.9	-1.2	-1.3	-0.6	-1.4	-1.1	-1.0	0.4	-1.8	-1.5	-1.5	-1.8	-1.4	-1.0	-0.2
Rheumatoid Arthritis	1.1	1.5	8.5	-1.2	-0.7	-1.0	-1.4	-0.4	-1.1	-1.4	0.0	-1.4	-1.7	-1.0	-1.1	-0.9	0.8	0.5	-1.2	0.9	-2.9	-0.4
Allergy	1.1	2.5	10.2	-1.2	-1.5	-1.2	-1.7	-1.6	-1.6	-1.8	-1.4	-1.3	-3.2	-1.9	-0.7	-1.1	-0.7	-0.3	-2.1	-0.6	-1.3	-2.0
Illnesses of siblings	1.1	1.6	7.9	0.4	-0.1	0.6	0.2	0.7	0.3	-0.5	0.8	-0.2	-0.5	-0.2	2.4	-0.3	-2.8	-2.0	0.7	-2.5	0.8	1.3
Medication: Cholesterol lowering	1.1	1.7	11.1	1.5	0.9	0.6	1.6	0.3	1.2	1.0	0.1	1.0	3.3	1.8	-0.3	0.9	1.7	0.8	1.1	1.1	0.7	1.2
Overall health rating	1.1	2.4	9.1	1.5	0.3	0.4	1.6	-0.1	1.4	1.5	-0.3	0.9	3.0	1.7	-0.7	0.8	2.3	1.0	2.2	1.9	1.9	2.2
Commuting to job workplace: Walk	1.1	1.2	4.9	-0.2	-1.0	-0.5	0.1	-0.9	-0.5	0.2	-0.7	0.3	-1.0	-0.0	-1.8	0.8	2.2	2.2	-0.3	2.1	-0.6	-0.7
Illnesses of father: High blood pressure	1.1	1.4	4.9	-0.8	-1.5	-1.1	-1.4	-2.2	-0.6	-0.8	-2.2	-0.8	-0.6	-0.3	-1.7	-1.5	1.2	-0.7	-0.3	1.1	0.4	0.4
Smoking Status	1.0	2.4	8.9	-1.4	-1.8	-1.1	-0.3	-1.7	-1.2	-0.7	-1.9	-0.5	-0.2	-0.7	-3.0	-0.1	2.1	1.9	-1.7	2.1	-1.6	-1.4
Cardiovascular Disease	1.0	3.2	8.7	2.0	1.4	1.6	2.1	0.4	1.6	1.8	0.3	2.2	2.3	2.1	-1.2	1.7	3.0	2.4	1.2	2.5	0.5	0.5
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	6.2	-0.6	-0.3	-0.6	-0.8	-1.1	-0.3	-0.6	-1.1	-0.1	-0.1	-0.4	-1.9	0.4	1.2	1.6	-1.3	0.8	-1.4	-2.5
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	5.0	2.0	0.7	1.0	1.0	1.1	1.0	1.1	1.2	1.1	0.2	2.2	0.7	1.3	0.5	0.1	0.1	0.5	1.1	1.2
Falls in the last year	1.0	1.3	3.1	1.1	1.2	1.8	1.1	1.2	1.7	1.6	1.3	1.5	0.1	1.1	1.1	1.5	0.1	0.4	0.9	-0.2	1.4	0.2
Number of children fathered	1.0	1.1	3.6	0.7	0.9	1.0	0.4	0.8	0.6	1.1	0.6	1.0	1.9	1.1	0.2	0.8	0.4	-0.4	1.8	0.7	1.7	1.7
Eye problems/disorders: None of the above	1.0	1.2	2.8	1.4	0.9	1.7	0.1	1.2	1.4	1.0	1.2	1.1	0.6	0.9	1.6	0.5	-1.3	0.0	0.6	-1.6	1.0	1.0
Medication: Ibuprofen	1.0	1.2	2.6	1.5	1.5	1.5	1.4	1.5	1.0	1.4	1.6	1.5	0.3	0.8	0.4	1.6	0.5	0.9	0.4	-0.2	-0.0	0.5
Illnesses of father: None of the above (group 1)	1.0	1.3	6.6	-1.0	-0.4	-0.3	-1.5	0.0	-2.0	-0.7	0.1	-0.7	-2.6	-1.8	-0.2	-1.0	-0.8	-0.6	-0.5	-1.1	-1.1	-1.0
Financial situation satisfaction	1.0	1.2	3.1	1.5	1.0	0.8	0.7	0.5	1.1	0.8	0.5	1.4	1.0	1.2	-0.7	1.8	1.3	1.6	-0.2	1.8	-0.3	0.4
Medication: Paracetamol	1.0	1.5	4.5	1.1	2.1	1.0	2.0	1.8	1.0	1.2	2.1	1.1	-0.3	1.1	0.7	2.0	0.4	0.8	0.1	0.1	-0.7	-0.6
Bipolar Disorder (2018)	0.9	1.4	4.0	1.5	0.1	1.5	1.4	1.1	1.0	1.4	0.7	1.4	2.0	1.1	0.3	1.0	0.4	0.7	1.6	0.3	1.4	1.4
Hearing difficulty/problems: Yes	0.9	1.3	3.4	-1.1	-1.6	-0.9	-1.3	-1.9	-1.0	-0.4	-1.7	-0.3	-1.5	-0.8	-1.8	-1.0	1.4	-0.2	0.4	1.5	0.0	-0.4
Medication: Metformin	0.9	1.3	4.1	0.8	1.0	1.0	1.7	0.6	1.1	0.9	0.5	1.2	1.4	1.3	-1.2	0.9	2.0	1.1	0.0	2.0	-0.4	-0.4
Body mass index (BMI)	0.9	3.6	17.1	-0.3	-2.0	-1.0	-0.4	-2.2	-1.1	0.1	-2.5	0.0	1.1	0.4	-4.1	-0.5	3.5	2.2	1.1	3.6	-0.1	-1.4
Had other major operations	0.9	1.1	4.1	-0.4	-1.1	-0.7	-0.6	-1.0	-0.3	-0.3	-1.3	-0.8	2.0	-0.1	0.3	-1.3	-1.2	-1.1	1.3	-1.0	1.6	0.9
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	8.7	-0.6	0.0	0.0	0.2	0.3	0.3	0.6	0.3	-0.1	0.3	-0.5	1.3	-0.5	-1.1	-1.6	3.0	-1.1	2.1	1.2
Time employed in main current job	0.9	1.0	4.6	-0.1	0.9	0.5	-0.2	1.1	-0.3	0.2	1.0	-0.1	0.0	-0.1	2.1	-0.0	-1.9	-1.5	-0.0	-2.0	1.2	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	3.6	-1.0	-1.9	-1.8	-0.5	-1.6	-1.4	-0.9	-1.8	-1.4	-0.2	-1.0	-1.7	-0.8	1.4	0.5	-0.4	1.6	-0.2	-0.4
Commuting to job workplace: Public transport	0.9	1.1	3.5	-0.9	-1.1	-1.4	-0.4	-0.7	-1.1	-0.9	-0.6	-1.3	-1.9	-0.7	0.3	-1.4	-1.0	-1.0	-1.1	-1.2	-0.4	-1.3
High cholesterol (Self-reported)	0.9	1.6	8.4	0.8	0.9	1.2	0.9	0.3	1.6	1.2	0.1	1.1	2.9	1.3	0.5	0.2	0.9	0.1	1.5	0.4	1.7	2.0
Vascular/heart problems diagnosed by doctor	0.9	2.5	6.6	-1.6	-1.0	-0.3	-2.5	0.2	-1.4	-1.0	0.3	-1.2	-2.4	-1.7	1.5	-2.1	-2.5	-2.1	-0.3	-2.6	-0.4	0.5
Pain experienced in last month	0.9	1.4	7.8	-0.2	0.1	1.0	-0.0	0.2	0.6	-0.3	0.4	0.3	-0.1	-0.2	2.2	-0.6	-2.8	-2.1	0.2	-2.2	1.2	1.2
Heart attack/myocardial infarction (self-reported)	0.9	1.2	5.7	-0.3	-1.2	-1.2	0.4	-1.5	-0.6	-0.3	-1.6	-0.6	0.8	-0.1	-1.7	-0.5	1.9	0.8	0.3	2.4	0.2	-0.3
Impedance of whole body	0.9	4.7	18.0	1.8	1.8	2.1	1.8	2.7	2.4	1.1	3.0	1.3	-0.2	1.4	4.2	1.6	-3.2	-1.9	0.5	-2.3	1.8	2.1
Verbal and Numeric Reasoning (VNR)	0.8	1.9	4.5	-1.5	-0.9	-1.5	-1.4	-1.0	-1.9	-1.7	-1.0	-1.7	-2.1	-2.1	0.1	-1.1	-1.1	-0.3	-1.1	-1.2	-1.2	-1.2
Crohns Disease (2012)	0.8	1.3	4.7	0.8	0.7	1.6	0.3	1.1	1.7	1.6	0.0	1.4	1.1	0.9	1.2	0.6	-0.2	0.3	2.2	-1.0	1.2	1.5
LDL Cholesterol	0.8	1.2	5.1	0.9	0.8	1.3	0.9	0.5	0.6	1.2	0.5	1.2	0.9	0.6	0.8	0.6	-0.7	-1.2	1.5	0.1	2.3	2.1
Type 2 Diabetes (T2D) (2012)	0.8	0.9	3.5	-0.6	-0.8	-0.8	-0.7	-0.5	-0.6	-0.9	0.0	-0.9	-1.2	-0.6	1.1	-1.6	-1.8	-0.8	-1.0	-1.9	0.1	-0.2
BMI	0.8	4.4	20.6	-0.7	-1.9	-0.6	-0.6	-2.2	-1.2	-0.0	-2.4	0.4	0.1	0.2	-4.5	-0.5	3.9	3.2	0.2	3.8	-1.4	-2.1
Systolic Blood Pressure	0.8	4.2	10.6	2.6	3.3	1.8	3.0	2.2	2.5	2.2	2.2	2.4	2.2	2.1	0.9	2.4	1.2	1.3	1.0	0.9	0.8	1.6
Respiratory disease	0.8	1.8	8.0	0.8	1.3	1.0	1.3	0.8	1.8	1.4	0.6	1.1	2.8	1.3	-0.1	1.2	1.0	0.8	1.7	1.3	1.5	1.5
Number of treatments/medications taken	0.8	1.5	7.4	1.1	0.8	0.3	1.4	0.4	0.8	1.0	0.4	1.0	0.5	1.4	-1.2	1.1	2.7	2.2	-0.3	2.1	-0.5	-0.4
Relative age of first facial hair	0.8	1.6	5.7	-1.2	-0.8	-1.6	-0.7	-1.2	-1.1	-1.5	-1.2	-1.4	-1.4	-1.6	-1.1	-0.6	-0.1	0.2	-2.4	-0.0	-1.5	-1.4
Relative age voice broke	0.8	1.3	2.4	-1.3	-0.9	-1.0	-1.4	-1.4	-0.5	-1.5	-1.4	-1.0	-0.5	-1.5	-1.1	-1.5	0.7	-0.3	-1.5	0.5	-1.2	0.5
Serious illness, injury or assault to yourself	0.8	1.0	3.9	-0.4	0.3	-0.3	0.1	-0.2	-0.5	0.2	-0.2	0.1	-0.6	-0.4	-1.7	-0.5	1.8	2.0	-1.0	1.8	-1.1	-1.3
Heart attack	0.8	1.1	5.6	-0.3	-1.1	-1.1	0.5	-1.3	-0.4	-0.1	-1.4	-0.5	0.9	0.0	-1.6	-0.3	1.8	1.1	0.2	2.4	0.2	-0.3
Mouth/teeth dental problems: Dentures	0.8	1.4	7.6	1.1	0.6	1.0	1.2	0.2	1.3	0.9	-0.1	1.2	2.8	1.5	-0.7	0.7	1.1	0.7	0.9	1.8	1.0	1.2
Chronic bronchitis/emphysema (mother)	0.8	1.0	2.7	-0.9	-0.4	-1.4	-1.7	-1.3	-1.1	-1.1	-1.3	-1.3	-0.7	-1.1	-0.7	-1.5	-0.0	-0.9	-0.2	0.0	-0.1	-0.8
Worry too long after embarrassment	0.8	1.4	5.9	-0.2	-0.1	-0.2	-1.4	-0.1	0.0	-0.8	0.1	-0.7	-0.5	-0.8	2.2	-0.5	-2.0	-2.4	0.1	-2.2	1.1	0.6
Smoking status: Previous	0.8	1.2	6.4	0.6	-0.6	-0.6	0.7	-0.2	0.2	0.2	-0.3	-0.1	-0.3	0.8	-1.4	1.5	1.8	2.5	-1.5	1.3	-1.0	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	6.2	-2.1	-0.3	-0.6	-1.3	-0.1	-1.8	-0.4	-0.1	-0.6	-2.5	-2.2	-0.8	-1.7	0.1	0.7	-1.2	-0.1	-1.9	-0.9
Average weekly red wine intake	0.8	1.1	5.4	-1.0	-0.6	-0.9	-0.6	-0.7	-1.0	-0.5	-0.8	-0.2	-0.3	-0.8	-2.3	-0.3	1.7	0.6	-0.7	1.3	-1.9	-1.2
Number of self-reported non-cancer illnesses	0.8	1.4	7.2	0.6	0.1	-0.3	0.9	-0.8	0.9	0.7	-0.9	0.5	2.7	1.0	-1.2	0.5	1.9	0.9	1.6	1.8	1.1	0.9
Alcohol drinker status: Never	0.8	0.9	4.3	0.7	-0.2	-0.2	0.2	-0.2	-0.2	0.2	-0.1	0.3	-0.4	0.6	-1.7	1.0	2.0	1.2	-0.6	2.1	-1.5	0.1
Fractured/broken bones in last 5 years	0.8	1.0	3.7	1.1	1.0	0.3	1.9	0.5	1.1	0.7	0.5	0.6	0.6	1.2	-0.4	1.4	1.4	1.5	0.1	1.4	0.4	-0.8
Age at First Birth	0.7	1.0	4.1	-1.2	-0.5	-0.8	-1.8	-0.4	-1.4	-0.7	-0.4	-1.0	-2.0	-1.8	-0.5	-0.7	-0.3	0.4	-0.6	-0.4	-1.0	-0.6
Supplements: Zinc	0.7	0.8	4.6	-1.3	-0.3	-0.9	-1.0	-0.3	-0.9	-0.8	-0.3	-1.0	-0.6	-1.2	-0.1	-2.1	-0.1	-0.8	-0.2	-0.9	-0.9	-0.1
High blood pressure	0.7	1.9	5.2	1.7	1.1	0.3	2.2	0.1	1.5	0.7	0.0	0.9	2.3	1.9	-0.9	2.0	2.0	1.6	0.0	1.4	0.2	-0.7
Happiness	0.7	0.9	2.9	1.6	0.3	0.5	0.6	0.7	0.9	0.6	0.7	0.4	1.4	1.7	0.8	1.2	-0.2	-0.4	1.3	-0.3	0.7	1.1
Prospective memory result	0.7	0.8	2.1	-0.4	-0.8	-1.2	-0.7	-0.8	-0.9	-1.4	-0.7	-1.4	-1.1	-0.6	-0.2	-1.2	-0.5	-0.0	-1.3	-0.4	-1.3	-0.1
Pulse wave reflection index	0.7	0.9	3.7	0.7	0.4	0.3	0.3	0.6	0.4	0.9	0.5	0.5	1.3	0.8	1.2	-0.2	-0.7	-0.8	1.1	-0.9	1.7	1.9
Loud music exposure frequency	0.7	0.7	1.7	1.2	0.9	0.6	0.4	0.7	0.8	0.7	0.8	0.6	0.5	0.9	1.3	0.3	-1.3	-0.8	1.0	-0.7	1.1	1.0
Number of full brothers	0.7	0.9	3.4	0.5	0.7	0.4	1.3	0.9	-0.0	0.6	0.7	0.4	0.3	0.8	-0.7	0.5	1.5	1.6	0.1	1.8	-0.3	-1.5
Age at first live birth	0.7	1.2	5.3	0.4	0.9	0.8	0.1	1.7	0.2	0.5	1.8	0.3	-0.8	0.0	2.1	0.8	-1.7	-0.7	0.2	-2.3	-0.0	0.2
Emphysema/chronic bronchitis	0.7	0.8	2.8	0.5	0.4	0.0	1.4	0.4	0.3	1.1	0.3	0.5	0.2	1.1	-0.5	1.0	1.7	1.5	0.6	1.4	0.9	0.2
Alcohol intake frequency.	0.7	1.6	6.0	0.4	-1.8	-0.8	-1.4	-1.2	-1.2	-0.6	-1.3	-0.4	-0.1	0.4	-2.4	-0.1	1.9	1.4	-1.0	2.0	-1.6	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	3.7	0.4	-1.4	-0.9	-0.4	-0.8	-0.6	-0.9	-0.6	-0.4	-1.9	-0.4	-0.9	-0.6	0.7	0.9	-1.9	0.8	-1.6	-1.3
Medication: Blood pressure	0.7	1.4	4.2	-0.6	-0.8	-1.4	0.3	-1.5	-0.2	-0.9	-1.5	-0.9	0.2	-0.3	-2.1	0.8	1.6	1.3	-1.3	1.5	-1.0	-1.6
Medication: Atorvastatin	0.7	0.8	5.3	0.8	0.7	0.4	1.0	0.4	0.7	-0.5	0.2	0.1	1.9	0.6	1.2	-0.1	0.0	-1.1	0.0	-0.1	0.5	2.3
Irritability	0.7	1.3	4.5	0.3	1.2	0.8	1.2	1.1	0.8	0.3	1.2	0.7	-0.9	0.2	-0.4	1.6	2.0	1.4	-1.1	-0.0	-2.1	-1.0
Prostate Cancer	0.6	0.9	3.4	-1.0	-0.6	-0.6	-0.9	-0.4	-1.2	-1.0	-0.4	-1.1	-0.5	-0.8	0.7	-0.9	-1.8	-1.5	-0.3	-1.5	0.4	-0.0
HDL Cholesterol	0.6	1.0	2.9	-0.8	-0.8	-1.2	-0.3	-0.7	-0.6	-1.7	-0.6	-1.7	-0.6	-0.7	0.1	-0.4	-0.8	-1.4	-0.5	-1.4	-1.2	-1.6
Schizophrenia (2014)	0.6	1.3	7.9	0.2	0.4	0.3	0.5	0.4	0.8	0.1	0.4	-0.1	0.7	0.1	2.0	-0.4	-2.8	-1.4	0.2	-2.6	1.4	0.6
Blood Platelet Count	0.6	6.9	14.3	2.7	1.9	2.8	3.8	2.6	3.4	3.6	2.7	3.2	0.7	3.6	1.2	3.1	1.1	1.2	2.4	0.7	3.2	2.2
Trunk fat percentage	0.6	2.4	10.8	-0.4	-2.4	-0.9	-0.1	-1.8	-0.9	-0.0	-2.0	0.0	0.6	0.3	-3.3	-0.4	2.4	1.4	0.6	3.2	-0.1	-1.3
Hayfever, allergic rhinitis or eczema	0.6	1.3	3.1	0.6	1.2	1.1	1.0	1.7	0.8	1.3	1.6	0.8	1.8	1.1	1.4	1.1	-0.3	-0.6	1.6	-0.7	1.0	1.0
Hearing difficulty/problems with background noise	0.6	0.9	2.0	-0.8	-1.3	-1.1	-0.4	-1.2	-0.2	-1.3	-1.0	-1.2	-1.3	-1.0	0.5	0.0	-0.8	-1.4	-0.4	-1.4	0.2	-0.1
Mouth/teeth dental problems	0.6	1.0	3.2	0.4	1.2	0.6	1.5	1.3	0.8	0.6	1.4	0.1	0.6	0.8	1.7	0.9	-0.8	-0.5	0.5	-1.8	0.5	0.7
Diabetes (self-reported)	0.6	0.9	3.0	-0.6	-0.3	-0.9	-0.0	-1.0	-0.7	-1.1	-1.0	-1.0	0.3	-0.3	-1.2	-1.0	1.3	0.5	-1.3	0.6	-1.3	-1.7
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	7.8	-1.9	-0.7	-1.3	-2.2	-1.1	-1.6	-1.2	-0.9	-1.3	-2.8	-2.4	-0.5	-1.1	-0.6	0.6	-1.2	-0.7	-1.5	-1.1
Tense / ‘highly strung’	0.6	1.0	2.9	1.1	1.0	0.8	1.1	1.0	1.7	0.9	1.0	0.7	0.8	1.0	1.3	0.5	0.2	-0.2	0.8	-1.3	0.7	1.2
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	3.1	-0.9	-0.6	-1.1	-0.9	-0.6	-1.2	-1.5	-0.7	-1.3	-0.7	-0.9	-0.3	-0.5	-0.4	0.1	-1.3	-0.4	-1.8	-1.1
Headache pain in last month	0.6	1.0	3.5	-0.4	0.2	-0.4	-0.2	0.4	-0.9	0.4	0.3	-0.2	-0.8	-0.6	-1.3	0.6	1.9	1.9	-0.7	1.5	-1.7	-1.1
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	7.6	-0.9	-0.4	0.1	-1.2	0.3	-0.3	-0.3	0.5	-0.5	-2.8	-1.2	0.9	-0.2	-1.5	-0.4	-0.5	-1.4	-0.3	-0.7
Medication for pain relief, constipation, heartburn	0.6	1.1	4.8	-1.5	-0.7	-0.4	-1.1	-0.6	-0.0	-1.0	-0.6	-0.8	-1.0	-1.6	0.8	-1.5	-2.2	-1.3	-0.5	-1.0	0.3	0.5
Supplements: Vitamin C	0.6	0.8	3.1	-0.2	0.9	0.3	1.4	0.6	0.4	1.2	0.4	0.6	1.4	0.5	-0.5	-0.3	1.7	1.8	-0.0	0.8	0.0	0.2
Arm fat percentage (left)	0.6	2.3	9.6	0.1	-2.1	-0.8	0.1	-2.0	-0.5	-0.0	-2.3	-0.0	1.3	0.7	-3.1	-0.1	2.3	1.2	1.3	2.9	0.6	-0.6
Medication for cholesterol	0.6	0.8	2.4	-0.5	0.1	0.5	-0.6	0.6	-0.7	0.2	0.7	0.0	-0.4	-1.0	1.2	-1.3	-1.4	-1.5	1.2	-1.3	0.5	1.4
Back pain experienced in last month	0.6	0.9	4.6	0.6	0.4	-0.1	0.1	0.5	0.3	0.8	0.4	0.3	0.5	0.7	-1.0	1.6	2.1	1.9	-0.2	1.6	-0.2	-0.5
Osteoarthritis (self-reported)	0.6	0.7	4.0	-0.6	-0.6	-0.1	-0.7	-0.7	-0.4	0.4	-0.8	0.3	0.2	-0.2	-2.0	-0.1	1.4	1.1	0.7	1.9	-0.2	-0.4
Medication: Gliclazide	0.6	0.7	2.2	-0.5	-0.9	0.1	-0.7	-0.7	-0.2	-0.1	-0.8	0.1	1.5	-0.1	-1.1	-1.4	0.8	-0.5	1.4	1.3	0.2	0.5
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.5	-0.3	0.3	-0.4	-0.9	-0.4	-0.2	-0.8	-0.3	-0.8	-0.2	-0.7	1.1	-0.9	-1.5	-1.2	-0.7	-1.6	0.9	-0.2
Age started oral contraceptive pill	0.6	0.7	4.1	0.1	0.7	0.2	-0.6	0.6	-0.0	-0.6	0.6	-0.4	-0.1	-0.6	1.7	-0.6	-1.5	-1.0	-0.6	-2.0	-0.1	0.1
Basal cell carcinoma (self-reported)	0.6	0.8	2.8	1.0	0.1	0.4	1.7	0.9	1.1	0.3	1.0	0.2	-0.4	0.6	1.2	1.4	-0.8	-0.1	-0.4	-1.2	0.3	-0.9
Worry (Nagel 2018)	0.5	1.1	2.4	1.4	0.5	1.2	1.1	0.8	1.4	1.2	0.9	1.2	1.2	1.2	1.1	0.7	0.1	-0.4	1.6	-0.5	0.9	1.5
Irritable Bowel Disease (IBD)	0.5	1.1	4.5	-0.6	0.6	0.4	-0.1	0.8	0.5	-0.2	1.0	-0.1	-1.2	-0.6	2.1	-0.8	-1.4	-2.0	0.9	-1.6	0.8	1.3
Hypothyroidism (self reported)	0.5	1.0	3.0	0.2	-1.5	-0.9	-1.0	-0.9	-0.2	-1.6	-0.8	-1.2	-0.4	-0.1	0.7	-0.0	-1.7	-1.6	-1.2	-1.5	-0.4	0.1
Hand grip strength (left)	0.5	1.3	4.8	-2.2	-0.3	-1.3	-1.9	-0.6	-1.9	-0.4	-0.7	-1.0	-1.1	-2.0	-1.1	-1.4	0.5	-0.0	0.4	0.3	-0.6	-0.4
Maternal smoking around birth	0.5	0.8	2.2	-1.0	-0.7	-1.1	-1.1	-1.2	-0.5	-0.5	-1.2	-0.7	0.1	-0.8	-0.3	-1.5	-0.3	-1.2	1.1	0.1	0.9	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	2.6	-0.1	-1.6	-0.4	-0.1	-1.2	-0.2	0.1	-1.3	0.1	0.5	0.1	-1.3	-0.3	1.4	0.7	-0.6	1.2	0.8	0.2
Impedance of arm (right)	0.5	2.5	10.5	0.6	0.7	1.4	1.0	1.6	1.1	0.5	1.8	0.7	-0.4	0.4	3.2	0.8	-3.2	-2.0	0.9	-1.9	1.7	1.9
Arm fat percentage (right)	0.5	2.0	8.4	0.1	-1.8	-0.4	0.3	-1.7	-0.6	0.3	-2.0	0.3	1.2	0.7	-2.9	-0.0	2.1	1.2	1.6	2.9	0.9	-0.4
Qualifications: A levels/AS levels or equivalent	0.5	1.1	3.7	0.2	0.5	0.9	0.3	0.9	0.2	0.6	0.7	0.3	0.8	-0.1	1.7	-0.1	-1.8	-0.7	1.9	-1.8	1.3	1.4
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	3.1	0.6	-0.9	-0.2	0.5	0.4	-0.2	-0.1	0.2	0.1	-0.5	-0.3	-0.6	0.8	0.3	1.8	-1.1	0.3	-1.4	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.7	1.2	1.0	0.9	0.8	1.3	0.4	1.0	1.2	0.9	0.5	0.5	0.4	1.1	0.4	0.7	0.2	-0.3	-0.1	0.3
Depression (self-reported)	0.5	0.6	1.3	0.7	1.1	0.9	1.0	0.8	0.7	1.1	0.8	1.1	-0.1	0.5	0.6	0.8	0.6	0.4	0.6	0.1	1.0	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	5.2	-1.4	-0.4	-1.3	-1.8	-0.9	-1.2	-1.1	-0.9	-1.2	-2.3	-2.2	-0.5	-0.7	-0.4	0.5	-1.3	-0.6	-1.3	-0.7
Pulse wave Arterial Stiffness index	0.5	0.6	2.4	-0.1	-0.6	-0.5	-0.5	-0.5	0.1	-0.2	-0.5	-0.3	-0.2	-0.4	1.0	-0.4	-1.4	-0.8	0.8	-1.1	1.6	0.9
Length of working week for main job	0.5	0.6	2.4	-1.3	-0.5	-0.1	-0.7	-0.1	-0.9	-0.3	0.0	-0.4	-1.6	-0.8	-0.6	-0.1	0.5	0.7	-0.5	-0.0	-1.3	-1.4
Exposure to tobacco smoke at home	0.5	0.6	1.5	-0.6	-0.3	-1.2	-0.8	-0.9	-0.5	-1.1	-0.9	-1.2	-0.0	-1.0	-0.2	-0.7	-0.6	-0.3	-1.0	-0.3	-0.1	-1.1
High blood pressure (siblings)	0.5	0.7	2.6	-0.6	-0.3	-0.7	-0.9	-1.1	-0.3	0.3	-1.2	0.0	-0.2	-0.2	-1.6	-0.5	1.4	1.0	-0.5	0.9	0.2	-1.2
Body fat percentage	0.5	2.0	9.2	0.1	-1.9	-0.6	0.2	-1.6	-0.5	0.2	-1.8	0.2	1.2	0.7	-3.0	-0.2	2.3	1.3	1.1	3.0	0.3	-0.7
Comparative body size at age 10	0.5	1.5	4.0	-1.2	-1.9	-1.0	-1.1	-2.0	-1.1	-0.6	-2.0	-0.9	-0.2	-1.1	-1.3	-1.3	-0.1	-1.2	0.9	0.8	1.1	1.4
Pulse wave peak to peak time	0.5	0.6	3.9	-0.6	-0.0	-0.0	-0.2	0.0	-0.8	-0.4	0.1	-0.3	-0.4	-0.3	-1.2	-0.2	1.2	0.4	-1.1	1.0	-2.0	-1.2
Qualifications: College or University degree	0.5	1.5	7.0	-1.9	0.1	0.0	-0.5	0.1	-0.1	-0.3	0.1	-0.7	-0.6	-1.7	1.9	-0.8	-2.4	-1.2	0.6	-2.6	0.8	0.9
Age at last live birth	0.5	0.8	4.5	-0.4	0.1	0.1	-0.1	0.7	-0.4	-0.3	0.7	-0.5	-0.4	-0.9	1.5	-0.1	-1.9	-1.4	0.5	-2.1	0.1	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	3.4	0.8	0.2	0.4	-0.4	0.4	0.3	-0.4	0.3	-0.2	1.4	0.9	-0.1	0.8	0.8	-0.1	1.8	0.1	-0.6	1.2
Hypertension (Self-reported)	0.5	1.3	3.8	1.3	0.8	0.1	1.8	-0.2	1.1	0.5	-0.3	0.7	1.8	1.5	-1.0	1.6	1.9	1.3	-0.2	1.5	0.3	-0.5
Friendships satisfaction	0.5	0.6	2.8	-1.0	-0.5	-0.7	0.4	-0.1	-0.9	-0.3	-0.0	-1.0	-0.6	-1.1	1.0	-0.1	-1.7	-0.9	0.7	-1.2	0.3	0.1
Qualifications: nursing, teaching	0.5	0.8	2.1	-0.6	-1.4	-1.0	-0.8	-1.0	-1.0	-1.1	-1.0	-1.3	-0.6	-0.3	-0.4	-1.5	-0.6	-0.5	0.0	-1.2	-0.8	-0.7
Eye problems/disorders: Cataract	0.5	0.6	1.3	-0.7	-0.4	-0.8	-0.1	-0.8	-0.6	-0.6	-0.7	-0.6	-0.7	-0.8	-1.2	-0.6	0.9	0.5	-1.1	1.0	-1.1	-0.9
Ever smoked	0.5	0.8	2.6	1.2	-0.3	0.6	0.8	0.4	0.6	0.4	0.3	1.1	-0.0	1.0	-0.8	1.3	1.5	1.6	-1.1	1.4	-0.5	-0.0
Bipolar Disorder or Schizophrenia	0.4	0.9	3.8	1.2	0.1	0.7	1.4	0.6	1.0	0.9	0.3	0.7	2.0	1.1	0.7	0.6	-0.6	0.2	0.8	-0.7	1.3	1.2
Major Depression (MDD)	0.4	0.5	5.4	0.5	-0.4	-0.6	-0.5	-0.4	-0.2	-0.8	-0.3	-0.4	0.2	0.2	-0.3	0.4	-0.1	-0.1	-2.3	0.8	-0.6	-0.4
Coronary Artery Disease (CAD)	0.4	0.4	1.5	0.6	0.3	0.8	0.9	0.7	0.7	0.8	0.0	0.7	0.2	0.5	0.7	0.3	-0.9	-0.3	-0.3	0.0	1.2	1.0
Lupus	0.4	0.6	2.8	-0.6	-0.6	-0.3	-0.4	-1.0	-0.1	0.3	-1.1	0.0	0.9	0.3	-1.0	-0.9	0.4	0.2	0.6	1.7	1.1	0.9
Blood Eosinophil Count	0.4	3.2	9.9	-2.1	-1.6	-2.3	-0.3	-2.3	-1.2	-1.9	-2.1	-2.8	-0.2	-0.9	0.9	-1.3	-3.1	-2.6	1.0	-1.7	1.5	-0.3
Medication for hormone replacement therapy	0.4	0.4	1.5	0.4	0.4	-0.7	0.4	0.5	0.8	-0.0	0.5	-0.5	0.3	0.9	0.8	0.2	0.0	-0.1	-0.9	-1.0	0.5	-1.2
Severe depression (siblings)	0.4	0.4	2.6	0.6	-0.2	0.2	0.3	-0.5	0.3	0.1	-0.7	0.3	1.2	0.5	-0.7	-0.4	0.4	0.3	1.6	0.5	0.8	0.1
Hand grip strength (right)	0.4	1.1	3.8	-1.9	-0.6	-1.3	-1.4	-0.9	-1.2	-0.2	-1.0	-1.0	-0.4	-1.7	-1.4	-1.0	1.0	0.4	0.3	0.6	-0.3	-0.2
Past tobacco smoking	0.4	0.8	3.6	-1.0	0.1	-0.2	-0.9	-0.2	-0.5	-0.4	-0.2	-0.7	-0.1	-0.9	0.8	-1.3	-1.4	-1.9	1.0	-1.2	0.6	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	3.0	0.7	1.3	0.6	1.5	1.3	0.9	0.7	1.3	0.6	0.3	0.5	0.8	1.7	-0.4	0.6	0.8	-0.8	0.0	-0.2
Neuroticism score	0.4	0.8	2.2	1.4	0.5	0.8	0.9	0.6	1.3	0.8	0.7	0.6	0.5	1.0	1.4	0.7	-0.0	-0.4	0.4	-0.8	1.2	1.5
Number of live births	0.4	0.6	2.9	0.7	0.5	0.1	1.4	0.3	0.4	0.1	0.1	0.4	1.7	0.8	0.9	-0.4	-1.0	-1.1	-0.2	-0.3	1.0	0.7
Medication: Lansoprazole	0.4	0.5	2.1	-0.8	0.1	-0.7	-0.3	-0.5	-0.7	-0.6	-0.5	-0.8	-1.2	-0.5	-0.4	-0.0	-0.4	0.6	-0.6	-0.5	-0.7	-1.5
Illnesses of mother	0.4	0.5	1.3	0.8	0.1	1.1	0.7	0.6	0.8	0.5	0.6	1.2	0.3	0.9	1.0	0.0	-0.7	-0.5	0.6	-0.3	1.1	0.6
Impedance of arm (left)	0.4	1.9	8.5	0.5	0.2	0.9	0.7	1.0	1.3	-0.0	1.2	0.1	-0.4	0.2	2.9	0.6	-2.9	-2.0	0.2	-2.0	1.3	1.8
Breastfed as a baby	0.4	0.5	1.9	0.9	0.5	0.6	0.1	0.2	1.0	0.6	0.1	0.3	1.4	0.6	0.6	0.5	-0.1	0.3	0.7	-0.4	1.3	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.0	1.3	-0.0	0.7	0.8	0.3	1.0	1.0	0.3	1.0	0.5	1.3	0.5	0.4	0.6	0.2	1.1	-0.1	1.4	0.6
Medication: Paracetamol	0.4	0.7	2.5	1.1	1.3	0.6	1.2	1.0	0.6	0.7	1.3	0.5	0.0	1.2	0.8	1.6	0.0	0.1	0.4	-0.3	-0.2	-0.3
Health satisfaction	0.4	0.6	2.3	0.3	-1.1	-0.5	-0.7	-0.8	0.1	0.2	-0.9	-0.1	1.0	0.3	-1.0	0.3	0.7	0.7	1.1	1.5	0.6	0.3
Suffer from ‘nerves’	0.4	0.7	2.8	1.0	-0.5	-0.1	0.2	-0.1	-0.2	0.7	0.0	0.4	-0.6	1.2	-0.7	1.2	1.7	1.3	0.6	1.3	0.3	0.3
Commuting to job workplace: Car/motor vehicle	0.4	0.5	3.0	-0.1	-0.1	0.4	-0.7	-0.2	-0.6	0.2	-0.5	0.4	1.7	-0.4	-0.9	0.2	0.6	0.5	0.4	1.5	0.1	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	1.8	-0.0	-0.7	-0.8	0.0	-0.8	-0.6	-0.2	-0.8	-0.5	-0.1	0.1	-1.3	0.2	1.0	0.9	0.1	1.0	-0.5	-0.5
Mood swings	0.4	0.7	2.9	1.1	0.4	0.3	1.3	0.2	0.5	0.8	0.2	0.5	0.9	0.9	-0.0	0.8	1.3	0.5	-0.1	0.8	0.8	1.7
Miserableness	0.4	0.7	3.9	0.4	-0.3	-0.6	0.7	-0.6	-0.4	0.1	-0.6	0.0	0.2	0.3	-1.4	0.1	2.0	1.0	-1.2	1.5	-0.4	-0.3
Medication: Bendroflumethiazide	0.4	0.7	3.6	-0.0	-0.3	-0.6	-0.9	-1.2	-0.2	-0.8	-1.2	-0.6	0.6	0.1	-0.1	-1.1	-0.4	-1.9	0.2	-0.3	0.8	1.2
Leg fat percentage (left)	0.4	1.3	5.9	0.4	-1.0	-0.3	0.4	-1.0	-0.2	0.2	-1.2	0.2	1.5	1.3	-2.3	-0.2	1.9	1.0	1.1	2.4	0.4	-0.7
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.2	-0.6	-0.4	-0.6	-0.7	-1.1	-1.0	-0.4	-1.1	-0.4	-0.4	-0.9	-0.5	-0.8	0.2	-0.8	-0.0	0.7	0.7	0.4
Commuting to job workplace: Cycle	0.4	0.5	1.9	-0.3	0.5	-0.0	0.1	0.8	-0.5	-0.1	0.9	-0.3	-1.1	0.2	1.2	0.2	-1.1	-1.0	-0.3	-0.9	0.4	-1.4
Cholesterol lowering medication	0.4	0.6	3.5	1.2	0.6	0.7	0.8	0.0	1.3	-0.0	-0.1	0.2	1.9	1.1	0.5	0.7	0.7	0.1	-0.0	-0.0	0.3	0.7
Depressed Affect (Nagel 2018)	0.3	0.6	2.9	0.7	-0.2	-0.2	0.9	-0.3	0.1	0.5	-0.4	-0.1	1.6	0.9	-0.2	-0.4	1.3	-0.0	0.4	0.7	1.4	1.7
Depression (Nagel 2018)	0.3	0.5	1.6	0.9	-0.9	0.0	0.3	-0.6	0.3	0.0	-0.9	0.2	1.3	0.7	-0.9	0.1	1.0	0.7	-1.1	0.9	0.3	0.4
Neuroticism (Nagel 2018)	0.3	0.6	2.3	0.9	0.3	0.5	1.0	0.4	0.7	0.9	0.5	0.6	1.0	0.9	0.5	-0.0	0.7	-0.5	1.1	0.1	1.1	1.5
Breast Cancer	0.3	0.7	2.3	1.0	0.6	0.7	0.7	0.1	1.0	0.8	0.0	1.1	0.9	0.6	-1.1	0.4	1.2	1.5	0.0	1.2	-0.2	0.2
Neuroticism	0.3	0.8	2.0	1.4	0.6	0.7	1.0	0.7	1.1	0.9	0.8	0.5	0.7	1.2	1.2	0.5	-0.0	-0.5	1.1	-0.6	1.4	1.1
Systolic blood pressure, automated reading	0.3	0.8	3.0	0.9	1.4	0.4	1.7	0.6	1.2	0.5	0.5	0.7	1.5	0.5	0.2	1.1	0.5	0.7	-0.3	0.5	0.2	1.0
Average weekly fortified wine intake	0.3	0.4	1.3	-0.1	-0.8	0.1	-0.7	-0.8	0.3	-0.5	-0.8	-0.2	0.8	-0.1	0.1	-0.7	-0.9	-1.2	0.4	-0.6	0.5	0.7
Taking other prescription medications	0.3	0.5	2.3	0.9	0.2	-0.2	0.8	-0.1	0.4	0.2	-0.1	0.1	0.3	0.9	-1.0	0.2	1.5	1.1	-0.3	1.5	-0.4	-0.5
Age when periods started (menarche)	0.3	0.7	3.2	-0.5	0.8	0.8	0.3	1.2	0.2	0.6	1.2	0.7	-0.7	-0.7	1.0	0.6	-1.8	0.2	0.6	-1.6	-0.2	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.8	0.5	1.2	0.5	0.7	1.2	0.9	0.5	1.2	0.5	-0.1	0.4	0.2	1.7	0.2	1.0	0.4	-0.4	-0.5	-1.2
Supplements: Glucosamine	0.3	0.4	2.1	0.3	0.1	0.3	-0.4	0.6	-0.1	-0.2	0.6	-0.3	0.3	0.8	1.2	0.3	-0.7	-0.7	0.0	-1.4	0.0	1.0
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.2	0.7	1.1	0.7	1.0	0.8	0.7	0.4	0.9	0.3	-0.1	0.7	0.2	0.5	0.1	0.3	0.1	0.0	-0.7	-1.0
Medication: Atenolol	0.3	0.4	1.6	0.0	-0.9	-1.1	-0.5	-1.2	0.0	-0.6	-1.3	-0.6	0.7	-0.2	-0.3	-0.0	-0.3	-0.1	-0.7	0.6	0.7	0.3
Medication: Ramipril	0.3	0.4	2.3	0.1	-0.1	-0.1	-0.1	-0.2	-0.3	0.6	-0.2	0.4	-0.6	0.1	-0.9	0.3	1.2	1.5	-0.7	1.1	-0.1	-1.0
Father’s age at death	0.3	0.5	1.1	-0.9	-1.1	-0.6	-0.6	-0.4	-0.7	-0.4	-0.4	-0.8	-1.1	-0.9	-0.6	0.6	0.3	0.7	-0.5	0.0	-0.9	-0.4
Hair/balding pattern: Pattern 4	0.3	0.7	2.1	-1.1	-0.3	-0.3	-1.3	-0.7	-1.3	-0.3	-0.8	-0.3	0.2	-0.9	-1.0	-1.5	0.2	-1.4	1.2	0.2	-0.1	-0.0
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	2.5	0.4	-1.2	-0.9	-0.7	-0.8	-0.2	-1.3	-0.7	-1.1	-1.0	0.2	0.3	0.1	-0.8	-0.4	-1.6	-0.8	-0.5	-0.6
Leg fat percentage (right)	0.3	1.2	4.8	0.7	-0.8	-0.1	0.4	-0.8	0.1	0.4	-1.0	0.4	1.6	1.3	-1.9	0.0	1.8	1.0	1.3	2.2	0.6	-0.4
Exposure to tobacco smoke outside home	0.3	0.5	1.4	0.3	-0.5	-1.2	0.5	-1.0	-0.3	-0.8	-1.0	-1.1	0.5	0.0	-0.7	-0.4	-0.3	0.0	-1.1	0.5	-0.2	-0.3
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.9	-0.7	-0.7	-0.2	-0.3	-0.3	-1.4	-0.7	-0.2	-0.6	-0.9	-0.7	0.1	-0.2	-0.6	-0.8	0.3	-0.4	-0.7	0.2
Medication: Blood pressure	0.3	0.6	3.2	0.8	0.8	-0.3	1.1	-0.2	0.5	0.5	-0.3	0.4	1.8	1.1	-0.5	0.5	1.1	0.9	0.0	0.9	0.6	0.0
Pulse rate, automated reading	0.3	0.9	4.7	-1.1	-0.6	-0.9	-1.0	-0.5	-0.9	-1.1	-0.5	-1.0	-2.2	-1.2	-0.5	-1.0	0.0	-1.0	-0.6	-0.0	-0.5	-1.1
Chest pain or discomfort	0.3	0.5	5.1	0.3	-0.7	-0.5	0.6	-0.4	0.2	-0.0	-0.7	-0.1	2.2	0.7	-0.5	0.2	0.2	0.5	0.1	0.6	0.7	-0.5
Leg pain on walking	0.3	0.4	1.3	-0.1	-0.9	0.3	0.1	-0.6	0.4	0.8	-0.5	0.6	-0.4	0.2	-0.5	0.3	0.5	0.5	1.0	1.1	0.9	0.2
Illnesses of father: Heart disease	0.3	0.5	2.9	0.3	-0.4	-0.1	0.1	-0.0	0.3	0.5	-0.3	0.2	1.7	0.9	-0.1	0.3	0.7	0.6	0.3	0.8	1.2	1.1
Handedness (chirality/laterality): Left-handed	0.3	0.3	2.6	-0.0	0.0	-0.3	-0.1	0.0	-0.6	-0.5	0.1	-0.3	-0.7	-0.7	-0.3	-0.3	0.4	0.4	-1.0	0.3	-1.6	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.7	-0.1	-0.6	-0.6	0.8	-0.1	-0.8	-0.5	-0.2	-0.7	0.5	0.4	-0.3	-0.3	-0.5	-0.2	0.0	-0.5	-0.4	-1.3
Osteoporosis (self-reported)	0.3	0.3	1.8	0.7	0.4	-0.0	0.5	0.1	0.4	-0.9	-0.1	-0.5	1.3	0.4	0.6	0.0	0.0	-0.2	-0.6	-0.2	-0.4	0.9
Average weekly champagne plus white wine intake	0.3	0.4	1.1	-0.7	-0.8	-0.4	-1.0	-0.8	-0.6	-1.0	-0.9	-0.7	-0.6	-0.4	-0.5	-0.5	-0.1	-0.5	-0.3	-0.0	-0.4	-0.7
Guilty feelings	0.3	0.4	2.2	0.5	-0.4	0.3	-0.3	-0.1	0.4	-0.2	-0.0	-0.0	-1.0	0.2	0.9	0.0	-1.0	-1.5	0.0	-1.1	0.9	0.2
Wears glasses or contact lenses	0.3	0.4	1.7	-0.5	0.1	0.3	0.1	-0.0	0.4	-0.0	0.1	0.3	0.3	-1.0	0.9	-0.4	-1.3	-0.5	-0.4	-0.7	0.4	1.3
Ever taken oral contraceptive pill	0.3	0.4	2.2	0.2	0.7	0.0	0.8	0.4	0.2	0.5	0.3	0.4	0.3	0.3	-0.2	1.0	0.9	1.5	-0.7	0.4	-0.7	0.1
Medication: Lisinopril	0.3	0.4	2.1	-0.3	0.4	0.2	1.2	0.3	-0.0	0.4	0.3	0.6	-0.2	0.3	-0.8	0.1	1.5	1.2	0.3	1.1	-0.6	0.0
Unable to work because of sickness or disability	0.3	0.3	1.0	0.5	0.6	0.2	0.7	0.3	0.3	0.3	0.3	0.5	-0.9	-0.2	0.7	0.5	0.0	0.1	1.0	0.2	1.0	1.0
Myopia	0.3	0.5	2.0	0.4	0.2	1.1	-0.9	0.8	0.0	1.2	0.8	1.1	0.1	0.1	-0.2	-0.5	-0.1	0.0	1.4	0.1	0.1	0.9
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	2.0	0.1	-0.5	0.1	-0.2	-0.5	-0.3	-0.0	-0.5	0.0	0.9	0.5	-1.1	-0.0	1.4	0.7	0.1	0.9	-0.6	0.4
Reaction Time	0.2	0.3	1.5	0.7	0.0	0.7	0.6	0.6	1.1	0.3	0.6	0.3	-0.1	0.2	0.6	0.4	0.5	-0.3	0.5	-0.7	0.1	1.2
Body Mass Index (BMI) (2010)	0.2	0.2	1.0	-0.0	-0.4	-0.7	-0.0	-0.1	-0.5	-0.7	-0.1	-1.0	-0.0	-0.3	0.3	0.0	-0.7	-0.5	-0.3	-0.3	-0.5	-0.7
Mean Putamen Volume	0.2	0.3	0.9	-0.4	-0.5	-0.3	-0.7	-0.6	-0.2	0.0	-0.7	-0.1	0.6	0.0	-1.0	-0.6	0.8	-0.1	0.2	0.8	0.2	-0.2
Neuroticism (2016)	0.2	0.2	0.8	0.9	0.7	0.1	-0.3	0.2	0.7	0.2	0.2	0.5	0.6	0.3	0.6	0.5	-0.5	-0.4	-0.1	-0.3	-0.1	0.7
Triglycerides	0.2	0.3	0.8	0.1	-0.1	-0.5	-0.7	-0.6	-0.9	-0.6	-0.5	-0.4	-0.5	0.0	-0.4	-0.2	0.0	-0.9	-0.6	0.6	0.2	0.5
Chronotype (morning person)	0.2	0.5	2.6	0.4	-0.4	0.4	0.3	0.4	0.3	0.7	0.4	0.6	-0.8	0.9	-0.8	0.5	0.9	1.6	-0.4	0.4	-1.0	-0.5
Average weekly spirits intake	0.2	0.3	0.8	-0.1	-0.7	0.2	-0.2	-0.7	-0.2	-0.6	-0.7	0.2	0.1	-0.1	-0.5	-0.9	0.1	-0.9	-0.9	0.2	0.1	0.3
Sensitivity / hurt feelings	0.2	0.3	1.3	0.6	0.1	0.2	0.7	-0.1	0.3	-0.0	-0.0	0.1	0.6	0.3	0.8	-0.1	-0.6	-1.1	0.6	-0.2	0.7	1.1
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.4	0.3	-0.2	-0.3	-0.2	0.3	0.4	0.3	0.3	0.0	-0.0	0.9	0.2	-0.1	0.5	0.0	-0.2	-0.3	0.6	-1.2
Ever had hysterectomy (womb removed)	0.2	0.3	1.3	0.2	-0.1	0.2	-1.1	-0.5	-0.1	0.1	-0.5	0.3	0.4	0.1	-1.0	-0.8	0.7	-0.0	0.5	0.6	-0.2	0.3
Vitamin and mineral supplements	0.2	0.3	1.4	-0.1	-0.4	-0.4	-1.2	-0.4	-0.4	-0.3	-0.4	0.0	-0.6	-0.6	-1.2	0.1	0.5	0.1	-0.2	0.9	-0.4	-0.5
Diabetes (mother)	0.2	0.2	1.1	-0.0	-0.4	0.1	0.1	-0.4	0.1	0.1	-0.4	0.1	0.8	0.4	-0.8	0.1	1.0	0.3	0.5	1.0	0.4	0.2
Townsend deprivation index at recruitment	0.2	0.3	2.1	0.1	0.6	0.1	1.5	0.1	0.7	0.5	0.3	0.2	-0.2	0.7	0.4	0.8	-0.3	0.1	0.1	-0.1	0.6	-0.5
Current tobacco smoking	0.2	0.3	1.2	-1.1	-0.5	-0.4	0.1	-0.5	-0.9	-0.4	-0.6	-0.1	-0.2	-0.6	-1.0	-0.6	0.4	-0.1	-0.2	0.8	-0.5	-0.2
Fed-up feelings	0.2	0.4	2.0	0.9	-0.1	-0.2	1.0	-0.5	0.9	0.2	-0.4	-0.2	-0.1	0.7	0.5	0.4	0.8	0.2	0.2	-0.3	1.4	1.1
Medication: Levothyroxine sodium	0.2	0.4	2.4	0.1	-0.4	-0.5	-0.0	-0.4	0.1	-0.8	-0.3	-0.6	-0.7	-0.2	0.1	0.7	-0.7	-0.1	-1.6	-0.5	-0.8	-1.1
Chronic bronchitis/emphysema (father)	0.2	0.2	0.7	-0.2	-0.3	-0.6	0.8	-0.3	-0.0	-0.5	-0.1	-0.5	-0.5	-0.1	-0.4	0.3	0.5	0.2	0.2	0.8	-0.5	-0.7
Number of incorrect matches in round	0.2	0.3	1.3	-0.4	0.6	-0.5	-0.9	-0.1	-0.8	-0.4	-0.1	-0.8	0.1	-0.2	0.5	-0.6	-0.5	-0.9	0.4	-1.1	0.2	-0.0
Nervous feelings	0.2	0.3	1.7	0.6	-0.2	0.0	-0.5	-0.3	0.4	0.6	-0.2	0.4	-0.0	0.2	-0.5	-0.0	1.1	-0.2	1.3	0.4	0.3	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.8	0.3	-0.4	0.1	0.1	-0.2	0.1	0.5	-0.4	0.5	0.7	0.3	-0.7	-0.4	1.3	-0.0	0.4	1.0	0.7	0.1
Hair/balding pattern: Pattern 2	0.2	0.3	1.0	0.2	0.3	0.2	1.0	0.4	0.1	0.4	0.3	0.2	0.5	1.0	0.5	0.7	-0.1	0.4	0.6	-0.6	0.6	0.0
Had menopause	0.2	0.3	1.0	-0.9	0.3	-0.4	-1.0	-0.1	-0.7	-0.1	-0.1	-0.4	0.5	-0.7	0.0	-0.7	-0.3	-0.6	0.6	0.2	0.2	0.9
Qualifications: None of the above	0.2	0.4	1.3	1.1	0.5	0.6	1.0	0.4	0.7	0.7	0.5	0.9	0.7	0.8	0.4	0.6	-0.2	-0.3	-0.4	0.5	1.1	0.0
Hair/balding pattern: Pattern 3	0.2	0.3	1.2	-0.2	-0.6	-0.6	-0.1	-1.1	0.4	-1.0	-1.1	-0.8	-0.0	-0.9	-0.3	0.0	0.0	0.5	-0.4	0.4	-0.4	0.1
Pulse rate	0.2	0.4	1.2	0.3	0.9	0.9	0.6	0.8	1.1	0.3	0.8	0.5	-0.8	0.3	0.8	0.8	-0.4	0.1	0.1	-0.5	0.6	-0.1
Lung cancer (father)	0.2	0.2	1.5	-0.2	-0.1	0.3	0.4	0.4	-0.4	0.3	0.5	0.4	-1.0	-0.2	0.5	0.4	-1.2	-0.4	-0.1	-0.3	0.5	0.1
Peak expiratory flow (PEF)	0.2	0.4	1.0	-1.0	-0.3	-0.6	-0.6	-0.8	-0.5	-0.5	-0.9	-0.7	-0.4	-0.9	0.1	-0.3	-0.8	0.4	-0.0	-0.9	0.2	-0.6
Glaucoma (self-reported)	0.2	0.2	0.8	0.5	-0.9	-0.5	-0.3	-0.5	-0.1	-0.7	-0.5	-0.6	0.2	0.4	0.3	-0.2	-0.1	-0.5	0.6	0.2	0.4	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.9	-0.3	0.2	-0.1	0.5	-0.0	0.3	-0.0	0.1	-0.3	0.3	0.4	1.1	0.2	-0.7	-0.0	0.4	-1.4	0.5	0.4
Shortness of breath walking on level ground	0.2	0.3	1.3	0.3	-1.1	-0.5	-0.7	-0.3	0.0	-0.7	-0.6	-0.7	0.5	0.2	-0.6	0.5	-0.1	-0.3	0.4	0.3	-0.3	-0.4
Medication: Allopurinol	0.2	0.3	1.1	0.3	-0.6	0.0	0.5	-0.5	0.1	-0.3	-0.4	0.3	-0.6	-0.2	-0.9	-0.2	1.0	0.8	-0.2	0.5	-1.0	-0.6
Medication: Seretide 50 evohaler	0.2	0.3	1.1	-0.3	0.1	0.3	0.1	0.4	0.2	0.5	0.3	0.1	-0.1	-0.3	0.6	-0.0	-0.6	-0.6	1.1	-0.2	1.1	0.8
Mean time to correctly identify matches	0.2	0.4	2.5	0.8	-0.4	0.6	-0.1	-0.1	0.9	-0.3	-0.1	0.2	0.6	0.3	0.4	0.0	0.2	-1.1	0.3	-0.6	0.3	1.6
Number of full sisters	0.2	0.3	0.9	0.7	0.3	-0.0	0.5	0.5	0.4	-0.3	0.5	-0.3	0.9	0.2	0.3	0.9	-0.1	0.6	-0.1	-0.8	-0.9	-0.3
Illnesses of siblings: Diabetes	0.2	0.2	0.9	-0.4	-0.4	-0.5	-0.3	-0.3	-0.3	-0.2	-0.3	-0.2	0.4	-0.2	-0.7	0.2	0.5	0.4	-0.5	0.9	-0.5	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	0.9	0.8	0.8	-0.4	0.6	-0.0	0.9	-0.1	-0.0	-0.2	0.9	0.1	0.6	0.8	0.0	0.8	-0.4	-0.9	0.3	0.3
Risk taking	0.2	0.3	1.5	-0.6	0.1	0.1	0.3	0.2	-0.8	0.2	0.1	0.3	-0.7	-0.1	-0.8	-1.2	0.2	0.0	-0.0	0.8	-0.6	-0.9
Alcohol drinker status: Previous	0.2	0.2	0.7	0.2	0.4	-0.2	-0.2	0.1	-0.5	-0.6	0.0	-0.4	-0.6	-0.4	0.1	-0.7	-0.4	-0.0	-0.6	-0.4	-0.9	-0.2
Schizophrenia (2018)	0.1	0.3	1.1	0.3	0.0	-0.4	0.6	-0.2	0.5	0.1	-0.1	-0.3	0.9	0.6	0.7	-0.0	-1.0	-0.3	-0.3	-1.1	0.6	0.3
Crohns Disease (2017)	0.1	0.2	0.5	-0.2	-0.2	-0.0	-0.2	0.5	0.5	0.1	0.6	-0.1	-0.5	0.1	0.6	-0.1	0.4	-0.1	0.5	-0.7	-0.4	0.5
HbA1C	0.1	0.1	0.6	-0.2	-0.4	-0.3	-0.3	-0.1	-0.3	0.8	-0.2	-0.3	0.5	-0.1	-0.4	-0.5	0.3	0.1	0.2	0.2	0.7	-0.5
Blood Red Count	0.1	1.2	6.0	0.5	-0.7	0.7	0.1	-0.0	0.5	1.4	-0.1	1.2	1.0	1.0	-0.4	0.7	0.4	0.0	2.4	1.5	2.0	1.8
Blood White Count	0.1	0.6	2.0	-0.4	0.5	-0.6	1.3	-0.1	-0.2	0.4	-0.2	-0.2	0.9	0.4	-1.0	1.0	1.2	0.9	0.5	1.4	0.4	-0.7
Lung FVC	0.1	0.5	1.8	0.6	1.3	0.4	0.4	0.7	0.6	0.5	0.9	0.6	-0.3	0.3	0.2	1.3	-0.1	1.2	-0.9	-0.3	-0.6	-0.6
Hair Pigment	0.1	2.1	9.6	0.6	1.3	0.4	1.3	0.8	0.2	1.2	0.7	1.1	0.4	0.7	-2.1	1.0	3.1	2.4	0.1	2.7	-1.9	0.1
Tanning	0.1	1.1	7.8	0.4	0.1	0.5	1.4	0.1	0.8	1.0	0.2	1.1	0.1	0.6	-1.0	0.7	1.3	2.8	-0.5	1.5	0.0	-1.4
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.9	0.8	-0.6	-0.2	0.4	-0.6	0.3	0.1	-0.6	0.1	0.2	0.6	0.1	-0.3	0.3	0.1	-0.5	-0.0	0.9	0.3
Multivitamins +/- minerals	0.1	0.2	0.5	-0.1	-0.4	-0.3	0.5	-0.6	-0.2	-0.6	-0.4	-0.5	-0.4	-0.2	0.0	-0.4	-0.1	0.3	-0.7	-0.2	-0.7	-0.3
Stomach or abdominal pain in last month	0.1	0.2	1.0	-0.1	-0.4	-0.2	-0.5	0.1	-0.7	0.5	0.1	-0.1	-0.6	-0.2	-0.5	0.1	0.0	1.0	0.6	0.1	-0.5	-0.2
High blood pressure (mother)	0.1	0.1	1.0	-0.1	0.1	0.1	-1.0	0.1	-0.0	-0.1	0.0	-0.3	0.3	-0.0	-0.3	0.4	0.8	0.3	-0.2	-0.1	-0.5	-0.1
Worrier / anxious feelings	0.1	0.1	0.6	-0.1	-0.5	0.1	0.0	-0.1	0.4	0.4	0.0	0.1	0.8	0.1	0.2	0.1	0.4	-0.0	0.2	-0.5	-0.3	0.8
Noisy workplace	0.1	0.1	0.3	0.4	-0.2	0.2	-0.6	-0.5	0.2	-0.6	-0.3	-0.2	0.1	-0.0	-0.0	-0.5	-0.4	-0.4	0.2	-0.0	-0.2	0.2
Gout (self-reported)	0.1	0.2	1.4	0.1	0.0	0.2	1.2	0.1	0.2	-0.4	0.1	0.2	-0.0	-0.3	-0.2	-0.1	0.2	0.3	-0.5	-0.1	-1.0	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.4	0.0	-0.3	-0.2	-0.0	-0.1	-0.6	-0.2	-0.1	-0.2	-0.2	0.2	0.1	-0.3	0.2	-0.6	-0.4	-0.1	0.3	-0.5
Ever had bowel cancer screening	0.1	0.1	0.6	0.7	0.8	-0.1	0.2	0.1	0.1	0.2	0.2	0.3	-0.2	0.4	0.2	-0.3	-0.5	0.3	-0.2	-0.3	-0.2	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	0.6	0.7	0.4	0.7	-0.5	0.4	-0.2	0.3	0.4	0.7	-0.4	0.2	0.1	-0.3	-0.1	-0.2	0.3	0.2	0.1	-0.6
Smoking status: Current	0.1	0.2	0.6	-0.8	-0.2	-0.1	0.2	-0.4	-0.5	-0.3	-0.5	0.1	0.2	-0.4	-0.8	-0.3	0.3	-0.1	-0.1	0.5	-0.3	0.2
Eye problems/disorders: Glaucoma	0.1	0.1	0.6	-0.0	-0.0	-0.5	-0.1	-0.2	0.0	-0.8	-0.2	-0.6	-0.2	0.1	0.1	0.5	0.6	0.1	0.3	0.5	-0.5	-0.4
Diastolic blood pressure, automated reading	0.1	0.2	0.8	0.0	0.1	-0.7	0.6	-0.6	0.4	-0.6	-0.6	-0.4	-0.0	-0.6	-0.6	0.1	0.5	0.4	-0.9	0.3	-0.6	-0.1

Hub : Genes

CRELD1

Models

Trait associations