[Hub]/) : Traits : Trunk predicted mass : ← →

chr1:37,628,741-40,737,589

Best TWAS P=1.02e-10 · Best GWAS P=2.65e-11 conditioned to 0.00109

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Adrenal Gland	FHL3	0.24	0.15	enet	17	0.34	7.4e-13	5.06	6.5	1.0e-10	-0.02	0.01	0.99	TRUE
38	NTR	Blood	PABPC4	0.01	0.00	blup	383	0.00	2.8e-02	4.53	-6.5	1.0e-10	-0.68	0.05	0.48	TRUE
48	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FHL3	0.13	0.03	enet	6	0.05	4.9e-04	-5.81	6.3	2.4e-10	-0.07	0.00	0.94	FALSE
44	The Cancer Genome Atlas	Colon Adenocarcinoma	FHL3	0.10	0.05	lasso	2	0.06	2.9e-04	5.44	6.0	2.0e-09	-0.04	0.00	0.97	FALSE
28	GTEx	Pancreas	FHL3	0.17	0.05	lasso	3	0.10	6.6e-05	-5.81	6.0	2.5e-09	0.00	0.00	1.00	FALSE
13	GTEx	Breast Mammary Tissue (Female)	PABPC4	0.10	0.00	enet	9	0.01	1.5e-01	6.07	-6.0	2.6e-09	-0.83	0.03	0.47	FALSE
5	GTEx	Artery Aorta	FHL3	0.35	0.22	lasso	4	0.27	3.9e-15	5.06	5.9	4.5e-09	-0.05	0.01	0.99	FALSE
46	The Cancer Genome Atlas	Brain Lower Grade Glioma	INPP5B	0.05	0.03	blup	68	0.05	6.7e-06	4.95	5.8	8.9e-09	-0.05	0.03	0.96	FALSE
9	GTEx	Artery Tibial	FHL3	0.13	0.11	lasso	2	0.13	1.1e-10	5.44	5.7	1.0e-08	-0.06	0.02	0.98	FALSE
47	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FHL3	0.08	0.08	lasso	2	0.08	1.4e-09	-5.81	5.7	1.1e-08	0.01	0.00	1.00	FALSE
14	GTEx	Cells EBV-transformed lymphocytes	SF3A3	0.23	0.11	enet	18	0.09	5.8e-04	5.44	5.7	1.2e-08	-0.05	0.02	0.93	FALSE
49	The Cancer Genome Atlas	Stomach Adenocarcinoma	FHL3	0.10	0.05	lasso	2	0.03	2.2e-03	-5.81	5.7	1.5e-08	-0.01	0.00	0.96	FALSE
3	GTEx	Adrenal Gland	PABPC4	0.20	0.09	lasso	8	0.06	3.0e-03	4.53	-5.7	1.6e-08	-0.77	0.05	0.80	FALSE
11	GTEx	Artery Tibial	UTP11L	0.09	0.14	lasso	3	0.12	1.1e-09	5.44	5.7	1.6e-08	-0.06	0.02	0.98	FALSE
1	GTEx	Adipose Visceral Omentum	FHL3	0.10	0.02	enet	9	0.00	1.9e-01	5.30	5.6	2.2e-08	-0.07	0.05	0.81	FALSE
17	GTEx	Esophagus Mucosa	FHL3	0.14	0.14	lasso	5	0.12	3.4e-08	5.44	5.6	2.2e-08	-0.07	0.03	0.97	FALSE
32	GTEx	Skin Sun Exposed Lower leg	FHL3	0.15	0.09	lasso	5	0.10	1.2e-08	-5.81	5.6	2.3e-08	-0.01	0.00	1.00	FALSE
37	NTR	Blood	KIAA0754	0.03	0.00	bslmm	366	0.01	1.6e-03	-0.85	5.6	2.5e-08	0.62	0.09	0.77	FALSE
31	GTEx	Skin Sun Exposed Lower leg	RP11-69E11.4	0.13	0.12	lasso	6	0.15	1.3e-12	5.80	5.5	3.0e-08	0.72	0.34	0.66	FALSE
39	NTR	Blood	SF3A3	0.10	0.12	lasso	6	0.13	7.2e-39	-5.83	-5.5	3.7e-08	0.01	0.00	1.00	FALSE
15	GTEx	Cells Transformed fibroblasts	FHL3	0.24	0.17	lasso	4	0.15	1.4e-11	5.44	5.5	4.2e-08	-0.06	0.02	0.98	FALSE
8	GTEx	Artery Coronary	RP11-109P14.10	0.26	0.10	enet	10	0.00	3.7e-01	5.06	5.5	4.6e-08	-0.07	0.02	0.96	FALSE
36	METSIM	Adipose	SF3A3	0.08	0.11	lasso	3	0.11	7.4e-16	5.44	5.4	5.3e-08	-0.07	0.04	0.96	FALSE
27	GTEx	Ovary	RP11-69E11.4	0.25	0.05	enet	11	0.03	6.7e-02	4.46	5.4	5.4e-08	0.68	0.05	0.43	FALSE
26	GTEx	Nerve Tibial	FHL3	0.20	0.12	lasso	7	0.14	1.9e-10	4.83	5.4	5.5e-08	-0.05	0.02	0.98	FALSE
35	METSIM	Adipose	FHL3	0.15	0.12	lasso	5	0.14	6.3e-20	-5.81	5.4	5.5e-08	-0.01	0.00	1.00	FALSE
50	The Cancer Genome Atlas	Thyroid Carcinoma	FHL3	0.12	0.03	enet	8	0.03	6.4e-04	4.83	5.4	6.3e-08	-0.06	0.01	0.99	FALSE
18	GTEx	Esophagus Mucosa	SF3A3	0.08	0.06	lasso	4	0.05	1.5e-04	5.44	5.4	7.7e-08	-0.07	0.04	0.95	FALSE
20	GTEx	Esophagus Mucosa	PPIEL	0.11	0.02	lasso	3	0.02	9.4e-03	5.61	5.3	9.4e-08	0.76	0.13	0.59	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	SF3A3	0.23	0.11	lasso	6	0.08	7.7e-04	5.44	5.3	1.0e-07	-0.08	0.04	0.93	FALSE
33	GTEx	Spleen	RP11-69E11.4	0.25	0.12	lasso	4	0.15	9.3e-05	4.05	5.3	1.1e-07	0.70	0.18	0.60	FALSE
41	YFS	Blood	SF3A3	0.50	0.29	enet	44	0.44	3.2e-162	5.44	5.3	1.1e-07	0.00	0.02	0.98	FALSE
2	GTEx	Adipose Visceral Omentum	SF3A3	0.20	0.18	lasso	2	0.18	1.5e-09	5.44	5.3	1.2e-07	-0.07	0.03	0.97	FALSE
25	GTEx	Lung	SF3A3	0.21	0.20	lasso	2	0.21	1.1e-15	5.44	5.3	1.2e-07	-0.07	0.03	0.97	FALSE
29	GTEx	Skin Not Sun Exposed Suprapubic	FHL3	0.11	0.11	lasso	4	0.07	1.0e-04	5.27	5.3	1.2e-07	-0.05	0.02	0.97	FALSE
34	GTEx	Thyroid	SF3A3	0.13	0.16	lasso	2	0.16	1.7e-12	5.06	5.3	1.3e-07	-0.07	0.04	0.96	FALSE
42	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FHL3	0.08	0.02	enet	7	0.03	1.1e-03	5.06	5.3	1.3e-07	0.02	0.00	0.95	FALSE
43	The Cancer Genome Atlas	Breast Invasive Carcinoma	FHL3	0.06	0.01	enet	10	0.01	4.2e-04	-5.81	5.3	1.3e-07	0.00	0.00	0.99	FALSE
45	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BMP8A	0.04	0.03	blup	48	0.04	3.5e-05	4.05	5.3	1.3e-07	0.68	0.02	0.97	FALSE
21	GTEx	Esophagus Muscularis	SF3A3	0.14	0.03	enet	13	0.06	2.9e-04	5.44	5.2	1.5e-07	-0.10	0.03	0.92	FALSE
10	GTEx	Artery Tibial	SF3A3	0.16	0.11	enet	8	0.12	1.2e-09	5.06	5.2	1.8e-07	-0.06	0.04	0.96	FALSE
23	GTEx	Heart Atrial Appendage	SF3A3	0.15	0.12	lasso	4	0.08	1.4e-04	5.06	5.2	1.8e-07	-0.07	0.05	0.88	FALSE
12	GTEx	Breast Mammary Tissue	SF3A3	0.14	0.18	lasso	2	0.16	8.5e-09	5.06	5.2	2.0e-07	-0.08	0.06	0.94	FALSE
24	GTEx	Lung	FHL3	0.14	0.07	enet	24	0.13	6.0e-10	4.95	5.2	2.0e-07	-0.01	0.02	0.98	FALSE
6	GTEx	Artery Aorta	INPP5B	0.21	0.13	lasso	3	0.21	5.5e-12	-3.86	5.2	2.2e-07	-0.03	0.12	0.88	FALSE
7	GTEx	Artery Coronary	FHL3	0.31	0.22	lasso	5	0.18	1.3e-06	5.06	5.2	2.3e-07	-0.07	0.04	0.94	FALSE
19	GTEx	Esophagus Mucosa	BMP8A	0.08	0.02	lasso	2	0.01	1.4e-01	-2.48	5.2	2.3e-07	0.69	0.08	0.86	FALSE
40	ROSMAP	Brain Pre-frontal Cortex	FHL3	0.07	0.06	enet	8	0.06	4.9e-08	4.83	5.2	2.5e-07	-0.08	0.07	0.93	FALSE
30	GTEx	Skin Not Sun Exposed Suprapubic	SF3A3	0.24	0.14	lasso	4	0.15	1.1e-08	5.06	5.2	2.6e-07	-0.07	0.06	0.94	FALSE
22	GTEx	Esophagus Muscularis	RP11-109P14.10	0.17	0.11	lasso	6	0.13	3.6e-08	-4.22	5.1	3.1e-07	-0.03	0.24	0.76	FALSE