[Hub]/) : Traits : Trunk predicted mass :

chr1:37,628,741-40,737,589

Best TWAS P=1.02e-10 · Best GWAS P=2.65e-11 conditioned to 0.00109

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum FHL3 0.10 0.02 enet 9 0.00 1.9e-01 5.30 5.6 2.2e-08 -0.07 0.05 0.81 FALSE
2 GTEx Adipose Visceral Omentum SF3A3 0.20 0.18 lasso 2 0.18 1.5e-09 5.44 5.3 1.2e-07 -0.07 0.03 0.97 FALSE
3 GTEx Adrenal Gland PABPC4 0.20 0.09 lasso 8 0.06 3.0e-03 4.53 -5.7 1.6e-08 -0.77 0.05 0.80 FALSE
4 GTEx Adrenal Gland FHL3 0.24 0.15 enet 17 0.34 7.4e-13 5.06 6.5 1.0e-10 -0.02 0.01 0.99 TRUE
5 GTEx Artery Aorta FHL3 0.35 0.22 lasso 4 0.27 3.9e-15 5.06 5.9 4.5e-09 -0.05 0.01 0.99 FALSE
6 GTEx Artery Aorta INPP5B 0.21 0.13 lasso 3 0.21 5.5e-12 -3.86 5.2 2.2e-07 -0.03 0.12 0.88 FALSE
7 GTEx Artery Coronary FHL3 0.31 0.22 lasso 5 0.18 1.3e-06 5.06 5.2 2.3e-07 -0.07 0.04 0.94 FALSE
8 GTEx Artery Coronary RP11-109P14.10 0.26 0.10 enet 10 0.00 3.7e-01 5.06 5.5 4.6e-08 -0.07 0.02 0.96 FALSE
9 GTEx Artery Tibial FHL3 0.13 0.11 lasso 2 0.13 1.1e-10 5.44 5.7 1.0e-08 -0.06 0.02 0.98 FALSE
10 GTEx Artery Tibial SF3A3 0.16 0.11 enet 8 0.12 1.2e-09 5.06 5.2 1.8e-07 -0.06 0.04 0.96 FALSE
11 GTEx Artery Tibial UTP11L 0.09 0.14 lasso 3 0.12 1.1e-09 5.44 5.7 1.6e-08 -0.06 0.02 0.98 FALSE
12 GTEx Breast Mammary Tissue SF3A3 0.14 0.18 lasso 2 0.16 8.5e-09 5.06 5.2 2.0e-07 -0.08 0.06 0.94 FALSE
13 GTEx Breast Mammary Tissue (Female) PABPC4 0.10 0.00 enet 9 0.01 1.5e-01 6.07 -6.0 2.6e-09 -0.83 0.03 0.47 FALSE
14 GTEx Cells EBV-transformed lymphocytes SF3A3 0.23 0.11 enet 18 0.09 5.8e-04 5.44 5.7 1.2e-08 -0.05 0.02 0.93 FALSE
15 GTEx Cells Transformed fibroblasts FHL3 0.24 0.17 lasso 4 0.15 1.4e-11 5.44 5.5 4.2e-08 -0.06 0.02 0.98 FALSE
16 GTEx Esophagus Gastroesophageal Junction SF3A3 0.23 0.11 lasso 6 0.08 7.7e-04 5.44 5.3 1.0e-07 -0.08 0.04 0.93 FALSE
17 GTEx Esophagus Mucosa FHL3 0.14 0.14 lasso 5 0.12 3.4e-08 5.44 5.6 2.2e-08 -0.07 0.03 0.97 FALSE
18 GTEx Esophagus Mucosa SF3A3 0.08 0.06 lasso 4 0.05 1.5e-04 5.44 5.4 7.7e-08 -0.07 0.04 0.95 FALSE
19 GTEx Esophagus Mucosa BMP8A 0.08 0.02 lasso 2 0.01 1.4e-01 -2.48 5.2 2.3e-07 0.69 0.08 0.86 FALSE
20 GTEx Esophagus Mucosa PPIEL 0.11 0.02 lasso 3 0.02 9.4e-03 5.61 5.3 9.4e-08 0.76 0.13 0.59 FALSE
21 GTEx Esophagus Muscularis SF3A3 0.14 0.03 enet 13 0.06 2.9e-04 5.44 5.2 1.5e-07 -0.10 0.03 0.92 FALSE
22 GTEx Esophagus Muscularis RP11-109P14.10 0.17 0.11 lasso 6 0.13 3.6e-08 -4.22 5.1 3.1e-07 -0.03 0.24 0.76 FALSE
23 GTEx Heart Atrial Appendage SF3A3 0.15 0.12 lasso 4 0.08 1.4e-04 5.06 5.2 1.8e-07 -0.07 0.05 0.88 FALSE
24 GTEx Lung FHL3 0.14 0.07 enet 24 0.13 6.0e-10 4.95 5.2 2.0e-07 -0.01 0.02 0.98 FALSE
25 GTEx Lung SF3A3 0.21 0.20 lasso 2 0.21 1.1e-15 5.44 5.3 1.2e-07 -0.07 0.03 0.97 FALSE
26 GTEx Nerve Tibial FHL3 0.20 0.12 lasso 7 0.14 1.9e-10 4.83 5.4 5.5e-08 -0.05 0.02 0.98 FALSE
27 GTEx Ovary RP11-69E11.4 0.25 0.05 enet 11 0.03 6.7e-02 4.46 5.4 5.4e-08 0.68 0.05 0.43 FALSE
28 GTEx Pancreas FHL3 0.17 0.05 lasso 3 0.10 6.6e-05 -5.81 6.0 2.5e-09 0.00 0.00 1.00 FALSE
29 GTEx Skin Not Sun Exposed Suprapubic FHL3 0.11 0.11 lasso 4 0.07 1.0e-04 5.27 5.3 1.2e-07 -0.05 0.02 0.97 FALSE
30 GTEx Skin Not Sun Exposed Suprapubic SF3A3 0.24 0.14 lasso 4 0.15 1.1e-08 5.06 5.2 2.6e-07 -0.07 0.06 0.94 FALSE
31 GTEx Skin Sun Exposed Lower leg RP11-69E11.4 0.13 0.12 lasso 6 0.15 1.3e-12 5.80 5.5 3.0e-08 0.72 0.34 0.66 FALSE
32 GTEx Skin Sun Exposed Lower leg FHL3 0.15 0.09 lasso 5 0.10 1.2e-08 -5.81 5.6 2.3e-08 -0.01 0.00 1.00 FALSE
33 GTEx Spleen RP11-69E11.4 0.25 0.12 lasso 4 0.15 9.3e-05 4.05 5.3 1.1e-07 0.70 0.18 0.60 FALSE
34 GTEx Thyroid SF3A3 0.13 0.16 lasso 2 0.16 1.7e-12 5.06 5.3 1.3e-07 -0.07 0.04 0.96 FALSE
35 METSIM Adipose FHL3 0.15 0.12 lasso 5 0.14 6.3e-20 -5.81 5.4 5.5e-08 -0.01 0.00 1.00 FALSE
36 METSIM Adipose SF3A3 0.08 0.11 lasso 3 0.11 7.4e-16 5.44 5.4 5.3e-08 -0.07 0.04 0.96 FALSE
37 NTR Blood KIAA0754 0.03 0.00 bslmm 366 0.01 1.6e-03 -0.85 5.6 2.5e-08 0.62 0.09 0.77 FALSE
38 NTR Blood PABPC4 0.01 0.00 blup 383 0.00 2.8e-02 4.53 -6.5 1.0e-10 -0.68 0.05 0.48 TRUE
39 NTR Blood SF3A3 0.10 0.12 lasso 6 0.13 7.2e-39 -5.83 -5.5 3.7e-08 0.01 0.00 1.00 FALSE
40 ROSMAP Brain Pre-frontal Cortex FHL3 0.07 0.06 enet 8 0.06 4.9e-08 4.83 5.2 2.5e-07 -0.08 0.07 0.93 FALSE
41 YFS Blood SF3A3 0.50 0.29 enet 44 0.44 3.2e-162 5.44 5.3 1.1e-07 0.00 0.02 0.98 FALSE
42 The Cancer Genome Atlas Bladder Urothelial Carcinoma FHL3 0.08 0.02 enet 7 0.03 1.1e-03 5.06 5.3 1.3e-07 0.02 0.00 0.95 FALSE
43 The Cancer Genome Atlas Breast Invasive Carcinoma FHL3 0.06 0.01 enet 10 0.01 4.2e-04 -5.81 5.3 1.3e-07 0.00 0.00 0.99 FALSE
44 The Cancer Genome Atlas Colon Adenocarcinoma FHL3 0.10 0.05 lasso 2 0.06 2.9e-04 5.44 6.0 2.0e-09 -0.04 0.00 0.97 FALSE
45 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BMP8A 0.04 0.03 blup 48 0.04 3.5e-05 4.05 5.3 1.3e-07 0.68 0.02 0.97 FALSE
46 The Cancer Genome Atlas Brain Lower Grade Glioma INPP5B 0.05 0.03 blup 68 0.05 6.7e-06 4.95 5.8 8.9e-09 -0.05 0.03 0.96 FALSE
47 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FHL3 0.08 0.08 lasso 2 0.08 1.4e-09 -5.81 5.7 1.1e-08 0.01 0.00 1.00 FALSE
48 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FHL3 0.13 0.03 enet 6 0.05 4.9e-04 -5.81 6.3 2.4e-10 -0.07 0.00 0.94 FALSE
49 The Cancer Genome Atlas Stomach Adenocarcinoma FHL3 0.10 0.05 lasso 2 0.03 2.2e-03 -5.81 5.7 1.5e-08 -0.01 0.00 0.96 FALSE
50 The Cancer Genome Atlas Thyroid Carcinoma FHL3 0.12 0.03 enet 8 0.03 6.4e-04 4.83 5.4 6.3e-08 -0.06 0.01 0.99 FALSE