Best TWAS P=1.13e-10 · Best GWAS P=3.12e-15 conditioned to 4.35e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | SENP6 | 0.08 | 0.00 | enet | 5 | 0.00 | 0.82400 | 6.6 | 6.5 | 1.1e-10 | 0.76 | 0.04 | 0.46 | TRUE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | MYO6 | 0.11 | 0.03 | lasso | 3 | 0.04 | 0.00206 | 6.6 | -5.2 | 1.7e-07 | -0.70 | 0.14 | 0.47 | FALSE |
| 3 | METSIM | Adipose | COL12A1 | 0.04 | 0.01 | blup | 309 | 0.02 | 0.00051 | -2.1 | -5.6 | 2.0e-08 | -0.48 | 0.12 | 0.53 | FALSE |