Best TWAS P=3.31e-21 · Best GWAS P=5.06e-35 conditioned to 1.76e-15
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HACE1 | 0.14 | 0.10 | enet | 28 | 0.11 | 8.9e-14 | 3.4 | -5.3 | 9.3e-08 | -0.42 | 1.00 | 0.00 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | LIN28B | 0.04 | 0.04 | lasso | 9 | 0.03 | 3.9e-05 | 10.0 | 9.4 | 3.3e-21 | 0.74 | 0.26 | 0.73 | TRUE |
| 3 | GTEx | Cells EBV-transformed lymphocytes | HACE1 | 0.40 | 0.15 | lasso | 8 | 0.22 | 1.1e-07 | 4.6 | -5.6 | 1.7e-08 | -0.43 | 0.56 | 0.36 | FALSE |