TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Relative age of first facial hair
:
←
→
chr6:104,478,130-106,230,491
Best TWAS P=3.31e-21 · Best GWAS P=5.06e-35 conditioned to 1.76e-15
104.4M
104.6M
104.8M
105M
105.2M
105.4M
105.6M
105.8M
106M
106.2M
0
10
20
30
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
CommonMind
Brain Pre-frontal Cortex
LIN28B
0.04
0.04
lasso
9
0.03
3.9e-05
10.0
9.4
3.3e-21
0.74
0.26
0.73
TRUE
3
GTEx
Cells EBV-transformed lymphocytes
HACE1
0.40
0.15
lasso
8
0.22
1.1e-07
4.6
-5.6
1.7e-08
-0.43
0.56
0.36
FALSE
1
CommonMind
Brain Pre-frontal Cortex
HACE1
0.14
0.10
enet
28
0.11
8.9e-14
3.4
-5.3
9.3e-08
-0.42
1.00
0.00
FALSE