Best TWAS P=1.03e-08 · Best GWAS P=1.1e-09 conditioned to 0.0229
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | TGM1 | 0.14 | 0.03 | enet | 21 | 0.03 | 5.1e-03 | -3.9 | 5.5 | 3.7e-08 | -0.75 | 0.02 | 0.96 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | ADCY4 | 0.07 | 0.02 | lasso | 4 | 0.03 | 4.7e-03 | -5.8 | -5.7 | 1.0e-08 | 0.86 | 0.01 | 0.90 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | NYNRIN | 0.05 | 0.02 | blup | 81 | 0.02 | 4.0e-03 | -4.4 | -5.3 | 1.5e-07 | 0.70 | 0.01 | 0.90 | FALSE |
| 4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | ADCY4 | 0.15 | 0.13 | lasso | 6 | 0.12 | 1.2e-05 | -5.7 | -5.7 | 1.2e-08 | 0.66 | 0.02 | 0.90 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | NFATC4 | 0.04 | 0.02 | blup | 66 | 0.02 | 1.1e-02 | -6.1 | 5.4 | 8.0e-08 | -0.77 | 0.00 | 0.96 | FALSE |