TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Relative age of first facial hair
:
←
→
chr14:24,020,127-25,430,242
Best TWAS P=1.03e-08 · Best GWAS P=1.1e-09 conditioned to 0.0229
24M
24.2M
24.4M
24.6M
24.8M
25M
25.2M
25.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Colon Adenocarcinoma
ADCY4
0.07
0.02
lasso
4
0.03
4.7e-03
-5.8
-5.7
1.0e-08
0.86
0.01
0.90
TRUE
4
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
ADCY4
0.15
0.13
lasso
6
0.12
1.2e-05
-5.7
-5.7
1.2e-08
0.66
0.02
0.90
FALSE
1
GTEx
Esophagus Mucosa
TGM1
0.14
0.03
enet
21
0.03
5.1e-03
-3.9
5.5
3.7e-08
-0.75
0.02
0.96
FALSE
5
The Cancer Genome Atlas
Thyroid Carcinoma
NFATC4
0.04
0.02
blup
66
0.02
1.1e-02
-6.1
5.4
8.0e-08
-0.77
0.00
0.96
FALSE
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
NYNRIN
0.05
0.02
blup
81
0.02
4.0e-03
-4.4
-5.3
1.5e-07
0.70
0.01
0.90
FALSE