[Hub]/) : Traits : Relative age of first facial hair :

chr21:39,849,553-41,383,143

Best TWAS P=7.38e-09 · Best GWAS P=1.82e-08 conditioned to 0.116

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PSMG1 0.19 0.24 enet 30 0.26 2.0e-31 -5.4 -5.5 4.5e-08 0.84 0.02 0.98 FALSE
2 GTEx Adipose Subcutaneous PSMG1 0.19 0.12 enet 26 0.13 4.1e-11 4.9 -5.2 1.7e-07 0.72 0.24 0.76 FALSE
3 GTEx Adipose Subcutaneous BRWD1-IT2 0.11 0.08 lasso 3 0.06 7.0e-06 -5.4 5.3 1.1e-07 -0.87 0.02 0.98 FALSE
4 GTEx Brain Cerebellum PSMG1 0.28 0.13 lasso 8 0.09 1.2e-03 -5.5 -5.5 4.8e-08 0.85 0.03 0.91 FALSE
5 GTEx Brain Hypothalamus PSMG1 0.46 0.20 lasso 5 0.16 1.5e-04 -5.4 -5.6 2.2e-08 0.81 0.04 0.94 FALSE
6 GTEx Colon Transverse PSMG1 0.23 0.19 lasso 5 0.22 1.4e-10 -5.3 -5.5 3.7e-08 0.82 0.03 0.97 FALSE
7 GTEx Esophagus Mucosa BRWD1-IT2 0.08 0.06 lasso 5 0.06 3.9e-05 4.5 5.4 6.0e-08 -0.88 0.04 0.94 FALSE
8 GTEx Muscle Skeletal PSMG1 0.13 0.16 enet 15 0.19 7.1e-18 5.5 -5.7 1.2e-08 0.81 0.01 0.99 FALSE
9 GTEx Nerve Tibial BRWD1-IT2 0.11 0.08 lasso 2 0.05 3.0e-04 -5.4 5.4 5.2e-08 -0.87 0.01 0.98 FALSE
10 GTEx Pancreas BRWD1-IT2 0.18 0.05 lasso 6 0.02 6.1e-02 -5.5 5.4 7.4e-08 -0.79 0.03 0.95 FALSE
11 GTEx Skin Not Sun Exposed Suprapubic BRWD1-IT2 0.13 0.09 lasso 3 0.08 2.5e-05 -5.4 5.2 2.1e-07 -0.86 0.02 0.98 FALSE
12 GTEx Testis PSMG1 0.30 0.10 lasso 4 0.06 9.5e-04 5.5 -5.1 2.7e-07 0.71 0.03 0.88 FALSE
13 GTEx Testis BRWD1-IT2 0.49 0.45 enet 19 0.46 9.0e-23 -5.0 -5.2 1.7e-07 0.86 0.03 0.97 FALSE
14 GTEx Thyroid BRWD1-IT2 0.16 0.13 lasso 6 0.14 1.1e-10 -5.4 5.5 3.5e-08 -0.85 0.02 0.98 FALSE
15 METSIM Adipose PSMG1 0.05 0.01 bslmm 638 0.02 3.6e-04 -5.6 -5.5 4.4e-08 0.78 0.02 0.98 FALSE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PSMG1 0.08 0.07 lasso 4 0.06 1.4e-07 -5.5 -5.5 4.6e-08 0.86 0.01 0.99 FALSE
17 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PSMG1 0.08 0.06 blup 61 0.06 2.5e-04 4.5 -5.4 8.1e-08 0.74 0.04 0.78 FALSE
18 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PSMG1 0.07 0.07 blup 61 0.04 6.3e-03 5.5 -5.5 3.5e-08 0.76 0.01 0.93 FALSE
19 The Cancer Genome Atlas Lung Adenocarcinoma PSMG1 0.04 0.02 blup 61 0.03 4.8e-04 4.7 -5.6 2.2e-08 0.76 0.01 0.98 FALSE
20 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PSMG1 0.04 0.04 blup 61 0.04 2.1e-05 -5.5 -5.8 7.4e-09 0.82 0.01 0.99 TRUE
21 The Cancer Genome Atlas Pancreatic Adenocarcinoma PSMG1 0.11 0.10 blup 61 0.08 2.2e-04 4.7 -5.5 4.5e-08 0.74 0.02 0.96 FALSE
22 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PSMG1 0.07 0.04 blup 61 0.06 1.7e-03 3.0 -5.5 4.8e-08 0.71 0.04 0.82 FALSE
23 The Cancer Genome Atlas Prostate Adenocarcinoma HMGN1 0.27 0.06 enet 17 0.10 2.5e-10 4.8 -5.2 1.7e-07 0.54 0.02 0.96 FALSE
24 The Cancer Genome Atlas Stomach Adenocarcinoma BRWD1 0.04 0.02 blup 97 0.03 2.3e-03 3.2 -5.2 2.5e-07 0.63 0.06 0.45 FALSE
25 The Cancer Genome Atlas Stomach Adenocarcinoma PSMG1 0.05 0.02 blup 61 0.02 1.4e-02 -5.4 -5.4 6.9e-08 0.83 0.01 0.93 FALSE