Hub : Genes

HMGN1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0620	0.0200	9.6e-05	0.023	0.024	0.026	0.024	0.025	6.3e-04	5.0e-04	3.4e-04	5.5e-04	3.8e-04
2	GTEx	Cells Transformed fibroblasts	0.0660	0.0290	5.2e-03	0.034	NA	0.027	NA	0.031	1.3e-03	NA	4.0e-03	NA	2.1e-03
3	GTEx	Esophagus Mucosa	0.1070	0.0410	1.8e-03	0.083	NA	0.065	NA	0.068	3.4e-06	NA	3.9e-05	NA	2.6e-05
4	GTEx	Testis	0.2150	0.0540	2.4e-06	0.220	NA	0.171	NA	0.211	4.0e-10	NA	4.8e-08	NA	9.7e-10
5	METSIM	Adipose	0.1076	0.0264	1.7e-12	0.127	0.085	0.093	0.101	0.114	1.7e-18	1.1e-12	8.0e-14	7.3e-15	9.7e-17
6	YFS	Blood	0.1740	0.0356	5.1e-11	0.034	0.049	0.064	0.064	0.048	2.1e-11	1.4e-15	3.4e-20	5.0e-20	2.4e-15
7	TCGA	Bladder Urothelial Carcinoma	0.0710	0.0320	6.5e-08	0.115	0.088	0.084	NA	0.088	5.8e-10	6.2e-08	1.4e-07	NA	6.2e-08
8	TCGA	Breast Invasive Carcinoma	0.0415	0.0172	5.6e-09	0.054	0.041	0.044	NA	0.047	3.7e-11	7.6e-09	2.0e-09	NA	5.9e-10
9	TCGA	Cervical Squamous Cell Carcinoma	0.1020	0.0650	5.1e-03	0.034	0.016	0.028	NA	0.042	8.8e-03	5.4e-02	1.6e-02	NA	3.7e-03
10	TCGA	Colon Adenocarcinoma	0.0640	0.0360	9.1e-04	0.029	0.045	0.042	NA	0.006	7.9e-03	1.3e-03	1.9e-03	NA	1.4e-01
11	TCGA	Glioblastoma Multiforme	0.1930	0.1020	6.6e-04	0.044	0.080	0.050	NA	0.064	1.7e-02	2.1e-03	1.2e-02	NA	5.3e-03
12	TCGA	Head and Neck Squamous Cell Carcinoma	0.0765	0.0307	1.1e-09	0.102	0.078	0.079	NA	0.095	1.7e-11	4.3e-09	3.2e-09	NA	8.7e-11
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.1708	0.0582	4.1e-13	0.144	0.127	0.121	NA	0.139	6.6e-16	3.6e-14	1.5e-13	NA	2.4e-15
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1340	0.0570	9.7e-07	0.124	0.113	0.141	NA	0.109	1.5e-07	5.2e-07	1.9e-08	NA	8.5e-07
15	TCGA	Brain Lower Grade Glioma	0.1391	0.0620	1.3e-08	0.077	0.077	0.076	NA	0.073	4.5e-09	3.9e-09	5.6e-09	NA	1.1e-08
16	TCGA	Liver Hepatocellular Carcinoma	0.1160	0.0540	4.0e-05	0.116	0.103	0.124	NA	0.120	4.4e-06	1.5e-05	1.9e-06	NA	2.9e-06
17	TCGA	Lung Adenocarcinoma	0.0985	0.0383	2.0e-08	0.077	0.082	0.076	NA	0.071	2.7e-09	8.6e-10	3.2e-09	NA	1.0e-08
18	TCGA	Lung Squamous Cell Carcinoma	0.0455	0.0283	5.7e-04	0.028	0.029	0.031	NA	0.031	3.0e-04	2.7e-04	1.6e-04	NA	1.6e-04
19	TCGA	Ovarian Serous Cystadenocarcinoma	0.0630	0.0370	1.8e-03	0.049	0.020	0.013	NA	0.016	2.8e-04	1.6e-02	4.3e-02	NA	2.7e-02
20	TCGA	Pheochromocytoma and Paraganglioma	0.1190	0.0640	1.5e-04	0.132	0.108	0.110	NA	0.117	6.3e-06	4.5e-05	3.9e-05	NA	2.2e-05
21	TCGA	Prostate Adenocarcinoma	0.2695	0.0997	1.4e-08	0.058	0.088	0.097	NA	0.070	1.0e-06	1.8e-09	2.5e-10	NA	8.4e-08
22	TCGA	Stomach Adenocarcinoma	0.0700	0.0350	5.4e-05	0.084	0.047	0.042	NA	0.062	1.1e-06	2.3e-04	5.1e-04	NA	2.9e-05
23	TCGA	Thyroid Carcinoma	0.1520	0.0550	5.6e-17	0.206	0.186	0.182	NA	0.195	8.8e-20	8.6e-18	1.8e-17	NA	9.9e-19
24	TCGA	Uterine Corpus Endometrial Carcinoma	0.2270	0.0910	4.4e-05	0.088	0.129	0.180	NA	0.163	2.0e-03	2.0e-04	9.6e-06	NA	2.7e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Age when periods started (menarche)	14.9	35.8	48.2	-4.7	-6.2	-6.5	-6.6	-6.3	0.5	-6.5	-6.5	-5.6	-6.9	-5.6	-6.2	-6.3	-5.7	-6.7	-6.3	-4.6	-6.0	-5.9	-6.4	-5.8	-6.2	-6.5	-5.9
Supplements: Glucosamine	10.8	14.1	22.0	3.5	3.8	3.8	4.1	4.0	0.8	4.1	4.1	3.2	3.9	3.4	4.0	4.0	3.3	3.4	3.6	4.7	3.6	4.7	3.5	3.9	4.0	3.8	2.8
Osteoarthritis (self-reported)	9.6	12.5	16.5	2.6	3.5	3.9	4.0	3.8	1.5	3.7	3.9	2.7	3.8	2.7	3.8	3.9	3.6	3.2	3.9	4.1	3.2	3.8	3.5	3.7	3.8	3.8	3.0
Relative age of first facial hair	9.4	19.3	27.3	-3.7	-4.3	-4.8	-4.9	-4.7	0.4	-4.7	-5.0	-3.4	-4.7	-3.7	-4.8	-4.8	-3.8	-5.1	-4.5	-3.0	-3.9	-3.8	-4.9	-5.2	-4.8	-4.9	-4.8
Average weekly beer plus cider intake	7.5	10.9	16.9	2.9	3.0	3.8	3.7	3.4	2.5	3.5	3.8	2.2	3.7	2.2	3.4	3.5	3.5	2.8	3.8	3.2	2.7	3.5	4.1	3.3	3.4	3.5	2.8
Relative age voice broke	7.0	10.7	18.7	-2.5	-3.2	-3.9	-3.6	-3.3	-0.5	-3.4	-3.7	-2.8	-3.7	-2.3	-3.3	-3.5	-3.4	-3.2	-3.8	-2.9	-3.0	-3.1	-4.3	-3.5	-3.3	-3.5	-2.8
Intelligence (Savage-Jansen 2018)	6.5	20.1	45.3	-3.5	-4.3	-5.4	-4.7	-4.2	-1.2	-4.4	-4.9	-3.2	-5.7	-2.4	-4.2	-4.6	-4.8	-4.6	-5.4	-3.7	-3.7	-4.9	-6.7	-5.6	-4.2	-4.6	-3.4
Blood Platelet Count	6.2	71.4	129.3	6.3	9.2	8.1	8.4	8.7	-2.5	9.2	8.7	9.1	10.6	10.8	8.7	8.7	4.9	11.4	7.3	4.4	9.2	8.0	7.3	8.0	8.7	8.9	9.9
Irritability	6.1	10.4	14.0	-1.8	-3.4	-3.5	-3.5	-3.4	-0.7	-3.4	-3.5	-3.2	-3.7	-2.5	-3.4	-3.5	-3.2	-3.7	-3.5	-2.2	-3.4	-3.0	-3.5	-3.3	-3.4	-3.5	-3.3
Pulse rate, automated reading	6.0	19.3	25.4	-3.7	-4.8	-4.5	-4.6	-4.5	-2.9	-4.7	-4.6	-5.0	-5.0	-4.6	-4.5	-4.5	-4.2	-4.7	-4.4	-3.3	-5.0	-4.2	-4.2	-3.5	-4.5	-4.6	-4.2
Chest pain or discomfort	5.9	8.5	17.1	-1.8	-2.9	-3.2	-2.9	-2.7	-0.5	-2.7	-3.0	-2.7	-3.7	-1.9	-2.7	-2.8	-3.2	-4.1	-3.3	-1.1	-2.7	-2.4	-4.1	-4.1	-2.7	-3.0	-3.1
Allergy	5.6	13.0	25.2	1.6	3.2	4.3	3.6	3.4	0.4	3.8	3.8	2.6	4.4	2.8	3.5	3.7	3.8	5.0	4.3	1.2	2.9	3.1	4.8	5.0	3.5	3.9	3.6
Pulse rate	5.3	9.0	12.1	-2.6	-3.3	-3.0	-3.2	-3.1	-1.5	-3.2	-3.1	-3.1	-3.4	-3.4	-3.1	-3.1	-2.8	-3.5	-2.9	-2.0	-3.2	-2.9	-2.7	-2.7	-3.1	-3.2	-3.0
Osteoporosis (self-reported)	5.1	6.3	8.8	-2.2	-2.7	-2.6	-2.7	-2.6	-0.0	-2.7	-2.8	-2.7	-2.7	-2.4	-2.6	-2.7	-2.1	-2.1	-2.5	-2.9	-2.8	-2.7	-3.0	-1.9	-2.6	-2.7	-2.0
Respiratory disease	5.0	11.1	25.1	-2.1	-2.9	-4.1	-3.4	-3.1	-1.2	-3.3	-3.6	-2.4	-3.9	-1.7	-3.1	-3.4	-4.0	-4.2	-4.2	-1.6	-2.6	-2.9	-5.0	-4.7	-3.1	-3.5	-2.9
Type 2 Diabetes (T2D) (2018)	4.9	9.2	12.7	3.6	3.1	3.3	3.3	3.5	1.7	3.4	3.4	2.1	2.9	2.4	3.5	3.5	3.0	3.1	3.2	2.3	2.6	2.6	2.3	2.8	3.5	3.5	3.4
Lung FEV1/FVC ratio	4.8	24.4	45.5	-5.0	-5.3	-4.2	-5.4	-5.6	1.8	-5.8	-5.2	-4.8	-5.2	-6.7	-5.6	-5.4	-2.7	-5.1	-3.7	-4.8	-5.3	-5.6	-2.3	-3.5	-5.6	-5.2	-5.4
Qualifications: O levels/GCSEs or equivalent	4.6	7.3	16.1	-1.9	-2.3	-3.3	-3.1	-2.7	0.6	-2.8	-3.2	-1.3	-3.2	-1.6	-2.8	-2.9	-2.7	-2.7	-3.2	-2.0	-1.8	-2.7	-4.0	-3.5	-2.8	-3.0	-2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	4.5	5.9	9.3	-1.7	-2.4	-2.3	-2.7	-2.7	-0.8	-2.6	-2.7	-2.1	-2.5	-2.3	-2.7	-2.7	-1.9	-3.0	-2.2	-1.7	-2.3	-2.0	-2.1	-2.9	-2.7	-2.7	-3.0
Number of incorrect matches in round	4.3	7.1	11.2	3.0	2.6	2.8	2.9	2.8	-0.1	3.0	2.8	2.1	3.1	2.3	2.8	2.8	2.7	2.8	2.8	2.5	2.4	3.4	2.6	2.6	2.8	2.7	2.2
Body mass index (BMI)	4.2	18.0	24.8	2.6	4.2	4.7	5.0	4.6	0.9	4.8	4.9	3.3	4.5	3.7	4.6	4.7	4.3	4.0	4.7	3.7	3.8	4.4	4.8	4.1	4.6	4.7	3.8
Past tobacco smoking	4.2	7.7	11.6	1.6	2.9	3.0	2.8	2.8	-1.1	3.1	3.0	3.1	3.4	3.2	2.8	2.9	2.8	3.0	3.0	1.2	3.0	1.9	3.1	1.8	2.8	3.2	3.4
Leg fat mass (right)	4.2	16.2	22.8	2.1	3.9	4.5	4.8	4.4	1.1	4.5	4.7	2.9	4.0	2.9	4.4	4.5	4.4	3.3	4.5	4.5	3.5	4.6	4.7	4.2	4.4	4.4	3.0
Alcohol drinker status: Previous	4.2	4.8	11.1	-1.0	-1.8	-2.9	-2.2	-2.2	-0.9	-2.1	-2.5	-1.3	-2.3	-0.7	-2.2	-2.3	-2.7	-2.2	-2.9	-1.8	-1.6	-1.7	-3.3	-3.1	-2.2	-2.5	-1.5
Medication: Allopurinol	4.1	5.4	9.5	1.5	2.6	2.2	2.4	2.6	1.5	2.5	2.5	2.4	2.2	2.4	2.5	2.5	2.1	3.1	2.1	1.0	2.4	1.4	2.1	2.3	2.5	2.6	3.1
Ever smoked	4.1	7.2	13.0	-1.5	-3.0	-3.1	-2.6	-2.5	0.3	-2.8	-2.8	-3.3	-3.6	-3.0	-2.5	-2.6	-3.0	-2.8	-3.1	-1.1	-3.1	-1.9	-3.3	-1.3	-2.5	-2.9	-3.0
Hayfever, allergic rhinitis or eczema	4.0	8.7	15.6	-2.0	-2.7	-3.6	-3.1	-3.0	0.5	-3.3	-3.2	-2.0	-3.3	-2.6	-3.1	-3.2	-3.1	-4.0	-3.5	-1.0	-2.3	-2.2	-3.2	-3.6	-3.1	-3.5	-3.1
Medication: Cholesterol lowering	4.0	6.2	8.4	2.7	2.6	2.9	2.6	2.6	0.7	2.7	2.7	2.3	2.9	2.1	2.6	2.7	2.6	2.4	2.9	1.8	2.5	2.5	2.6	2.0	2.6	2.7	2.2
Leg fat mass (left)	3.9	15.2	21.7	2.1	3.8	4.4	4.7	4.3	0.7	4.4	4.6	2.8	3.9	2.9	4.3	4.3	4.2	3.3	4.3	4.1	3.4	4.4	4.5	4.1	4.3	4.3	3.0
Allergy or Eczema	3.8	10.1	19.0	-1.8	-2.7	-4.1	-3.4	-3.3	-0.4	-3.3	-3.6	-1.8	-3.0	-1.6	-3.3	-3.5	-3.9	-3.7	-4.2	-1.6	-2.3	-2.1	-4.2	-4.4	-3.3	-3.8	-2.9
Arm fat percentage (left)	3.8	15.2	21.5	2.1	3.8	4.5	4.6	4.4	0.5	4.4	4.6	2.7	3.9	3.1	4.3	4.4	4.0	3.7	4.4	3.8	3.3	4.0	4.3	4.1	4.3	4.4	3.4
Leg fat percentage (left)	3.8	13.6	19.2	2.0	3.7	4.0	4.4	4.1	-0.5	4.3	4.2	3.1	3.9	3.6	4.1	4.1	3.6	3.3	3.9	3.5	3.5	4.3	3.8	3.3	4.1	4.1	3.2
Major Depression (MDD)	3.7	4.5	7.3	-2.1	-2.3	-2.1	-2.3	-2.1	-0.1	-2.1	-2.2	-2.3	-2.6	-2.3	-2.2	-2.2	-1.6	-2.7	-1.9	-1.4	-2.3	-2.2	-1.7	-2.0	-2.2	-2.1	-2.5
Hair/balding pattern: Pattern 3	3.7	5.5	7.9	2.5	2.6	2.5	2.3	2.2	1.8	2.4	2.4	2.7	2.8	2.3	2.2	2.3	2.5	1.9	2.5	2.1	2.7	2.6	2.5	1.3	2.2	2.3	1.9
Body fat percentage	3.7	14.7	20.7	1.9	3.7	4.4	4.6	4.3	0.3	4.4	4.5	2.7	3.8	2.9	4.3	4.4	4.1	3.3	4.4	3.9	3.3	4.1	4.2	3.9	4.3	4.3	3.2
Leg fat percentage (right)	3.7	13.3	18.5	1.8	3.7	4.0	4.3	4.0	0.0	4.2	4.2	3.0	3.9	3.4	4.0	4.0	3.6	3.1	3.9	3.7	3.4	4.2	3.9	3.1	4.0	4.0	3.1
Commuting to job workplace: Car/motor vehicle	3.7	4.3	5.8	1.8	2.2	2.0	2.3	2.4	1.9	2.3	2.2	1.8	1.6	1.9	2.4	2.3	1.9	2.1	1.9	2.1	2.1	2.0	1.2	2.0	2.4	2.3	1.8
Arm fat mass (left)	3.7	15.3	21.4	2.2	3.8	4.4	4.6	4.3	1.4	4.4	4.6	2.7	3.8	2.7	4.3	4.4	4.4	3.4	4.4	4.0	3.3	4.1	4.5	4.1	4.3	4.4	3.1
BMI	3.6	20.9	31.0	2.1	4.5	5.4	5.1	4.8	0.6	5.1	5.2	3.8	5.1	3.9	4.8	5.0	5.0	4.5	5.4	3.7	4.2	4.7	5.6	4.4	4.8	5.1	3.8
Hip circumference	3.6	15.5	25.6	2.2	3.9	4.7	4.4	4.2	2.2	4.2	4.5	3.0	4.0	2.2	4.1	4.3	5.1	3.3	4.8	3.7	3.5	4.0	5.0	3.9	4.1	4.3	2.6
Headache pain in last month	3.6	6.1	8.6	-1.5	-2.5	-2.9	-2.4	-2.5	-0.9	-2.4	-2.7	-2.7	-2.9	-1.7	-2.5	-2.6	-2.8	-2.8	-2.9	-1.9	-2.7	-2.1	-2.9	-2.6	-2.5	-2.7	-2.2
Whole body fat mass	3.6	15.2	21.4	1.9	3.7	4.5	4.6	4.3	1.2	4.3	4.6	2.7	3.8	2.6	4.3	4.4	4.4	3.2	4.4	4.3	3.3	4.3	4.5	4.2	4.3	4.3	2.9
Smoking status: Previous	3.6	5.3	7.8	-1.8	-2.5	-2.4	-2.4	-2.4	1.3	-2.6	-2.5	-2.5	-2.7	-2.6	-2.3	-2.4	-2.2	-2.1	-2.3	-1.5	-2.5	-1.8	-2.6	-1.4	-2.3	-2.6	-2.8
Loneliness, isolation	3.6	5.0	9.0	1.9	2.2	2.3	2.6	2.4	-1.3	2.7	2.5	1.6	2.5	2.3	2.4	2.4	1.9	1.9	2.1	2.3	1.9	3.0	2.4	2.0	2.4	2.3	1.7
Arm fat mass (right)	3.5	14.4	20.3	2.0	3.7	4.4	4.5	4.2	0.9	4.3	4.4	2.6	3.7	2.7	4.2	4.3	4.2	3.3	4.3	3.9	3.2	4.0	4.5	4.0	4.2	4.2	2.9
Peak expiratory flow (PEF)	3.5	8.0	13.0	-3.5	-3.0	-3.0	-2.9	-3.2	0.7	-3.4	-3.0	-2.3	-2.9	-3.6	-3.2	-3.2	-2.3	-3.1	-2.8	-1.8	-2.6	-2.3	-1.6	-2.0	-3.2	-3.3	-3.2
Length of working week for main job	3.4	3.7	7.2	-1.4	-2.2	-2.2	-1.9	-2.0	-1.3	-2.0	-2.1	-2.2	-1.8	-1.4	-2.0	-2.1	-2.7	-2.2	-2.3	-1.2	-2.2	-1.3	-1.8	-1.4	-2.0	-2.1	-1.7
Mean time to correctly identify matches	3.4	6.6	11.2	1.9	2.7	2.7	3.0	3.2	0.9	3.0	3.0	1.9	2.0	2.6	3.2	3.1	2.5	2.5	2.6	1.9	2.3	1.6	1.4	1.8	3.2	3.2	3.3
Medication: Omeprazole	3.3	4.0	6.9	2.6	2.1	2.2	2.3	2.2	0.3	2.2	2.2	1.8	1.7	1.9	2.2	2.2	2.0	1.4	2.1	2.3	2.0	1.9	1.9	1.4	2.2	2.2	1.4
Illnesses of father: Heart disease	3.3	4.6	6.5	-2.1	-2.4	-2.0	-2.0	-2.1	-1.8	-2.4	-2.2	-2.5	-2.4	-2.3	-2.2	-2.2	-1.8	-2.4	-1.9	-2.0	-2.5	-2.5	-2.0	-1.6	-2.2	-2.1	-1.6
Mood swings	3.3	6.0	7.7	-2.5	-2.7	-2.4	-2.7	-2.6	0.1	-2.7	-2.7	-2.6	-2.8	-2.6	-2.7	-2.6	-2.1	-2.5	-2.3	-1.7	-2.7	-2.5	-2.0	-1.7	-2.7	-2.6	-2.6
Trunk fat percentage	3.2	12.9	18.6	1.5	3.3	4.3	4.2	4.0	0.5	4.0	4.2	2.1	3.5	2.2	4.0	4.1	4.1	3.1	4.3	3.8	2.8	3.8	4.2	4.0	4.0	4.1	2.8
Arm fat percentage (right)	3.2	12.7	17.9	1.8	3.4	4.1	4.2	4.0	-0.1	4.1	4.2	2.5	3.5	2.9	4.0	4.0	3.7	3.3	4.0	3.5	3.1	3.6	3.9	3.7	4.0	4.1	3.0
Illnesses of father: None of the above (group 1)	3.1	3.9	5.6	1.1	2.2	1.8	2.1	2.2	1.0	2.3	2.2	2.2	1.9	2.3	2.2	2.1	1.7	2.4	1.7	1.2	2.2	1.6	1.9	1.4	2.2	2.2	2.0
Alcohol drinker status: Never	3.1	3.7	9.3	-1.3	-1.7	-2.4	-1.9	-1.7	0.1	-1.6	-2.0	-1.4	-2.2	-0.5	-1.7	-1.9	-2.5	-1.9	-2.6	-2.1	-1.6	-1.9	-3.1	-2.8	-1.7	-1.9	-1.1
Impedance of arm (right)	3.0	13.8	18.9	-3.5	-4.0	-3.8	-4.1	-3.9	-1.4	-4.3	-4.0	-3.7	-4.3	-4.2	-3.9	-3.9	-3.4	-3.7	-3.7	-2.5	-3.9	-4.0	-3.7	-2.6	-3.9	-3.9	-3.5
Knee pain experienced in last month	3.0	4.7	7.5	1.7	1.9	2.3	2.5	2.4	0.8	2.5	2.3	1.3	2.1	2.1	2.5	2.4	2.0	2.3	2.2	2.6	1.8	2.7	1.2	2.6	2.5	2.3	1.7
Mean Putamen Volume	2.9	3.4	6.6	-1.9	-2.3	-1.4	-1.8	-2.1	-0.8	-2.0	-1.8	-2.4	-2.1	-2.4	-2.0	-1.9	-1.3	-1.8	-1.3	-1.1	-2.3	-2.0	-0.5	-0.6	-2.0	-1.8	-2.6
Hayfever/allergic rhinitis (self-reported)	2.9	3.8	7.8	-0.2	-1.9	-2.5	-2.1	-2.1	-1.8	-2.2	-2.2	-1.3	-1.6	-1.2	-2.1	-2.2	-2.8	-1.9	-2.6	-1.1	-1.6	-1.4	-2.2	-1.8	-2.1	-2.3	-1.5
Wheeze or whistling in the chest in last year	2.9	5.2	11.2	-1.1	-2.4	-2.4	-1.9	-1.8	-0.0	-2.3	-2.1	-3.1	-3.3	-2.6	-1.8	-2.0	-1.9	-2.8	-2.4	-1.5	-2.8	-2.8	-3.2	-2.0	-1.8	-2.1	-1.4
Heart disease (siblings)	2.9	3.5	5.7	-2.0	-2.1	-1.8	-1.6	-1.8	0.2	-1.9	-1.7	-2.2	-2.0	-1.5	-1.9	-1.9	-1.9	-2.4	-1.8	-2.1	-2.2	-2.4	-1.4	-2.1	-1.9	-1.7	-1.3
Trunk fat mass	2.8	11.8	17.8	1.3	3.1	4.1	4.0	3.8	1.0	3.8	4.1	1.9	3.3	1.7	3.8	3.9	4.1	2.6	4.2	4.1	2.6	3.9	4.2	3.9	3.8	3.8	2.2
Sensitivity / hurt feelings	2.7	4.6	10.0	-2.9	-2.2	-1.9	-2.3	-2.2	0.3	-2.4	-2.1	-2.2	-2.5	-3.2	-2.2	-2.2	-0.9	-2.7	-1.6	-0.9	-2.3	-2.1	-1.1	-1.6	-2.2	-2.2	-3.0
Ever used hormone-replacement therapy (HRT)	2.7	3.4	8.1	2.0	1.6	2.1	2.1	2.0	-0.0	1.9	2.1	0.7	1.8	1.2	2.0	2.1	1.6	2.1	2.0	1.7	1.2	2.0	1.9	2.9	2.0	2.0	1.5
Waist circumference	2.7	10.0	13.6	1.9	3.1	3.6	3.7	3.5	-0.1	3.7	3.6	2.2	3.4	2.7	3.4	3.5	3.3	3.2	3.6	2.6	2.7	3.4	3.5	3.3	3.4	3.6	2.6
Medication: Simvastatin	2.7	4.0	6.2	2.0	2.1	2.4	2.2	2.2	0.7	2.3	2.2	1.6	1.9	1.7	2.2	2.3	2.5	1.5	2.5	2.0	1.8	2.1	1.6	1.2	2.2	2.3	1.4
Eye problems/disorders: Glaucoma	2.7	3.2	4.9	-1.0	-2.2	-1.6	-1.9	-2.0	-1.8	-1.9	-1.9	-2.2	-1.6	-1.8	-2.0	-1.9	-1.6	-1.6	-1.5	-1.5	-2.2	-1.4	-1.1	-0.8	-2.0	-1.9	-2.2
Qualifications: CSEs or equivalent	2.6	3.4	5.2	0.3	1.9	2.0	2.1	2.1	1.5	1.9	2.1	1.5	1.7	1.7	2.1	2.1	1.8	2.1	1.9	0.9	1.7	0.7	1.9	2.0	2.1	2.3	2.2
Medication: Lansoprazole	2.6	2.9	4.0	-1.7	-1.8	-1.7	-1.8	-1.7	0.8	-1.7	-1.8	-1.6	-1.9	-1.4	-1.7	-1.7	-1.4	-1.7	-1.6	-2.0	-1.7	-1.5	-2.0	-2.0	-1.7	-1.8	-1.9
Chronic bronchitis/emphysema (mother)	2.6	3.1	5.2	-1.0	-1.8	-1.9	-1.7	-1.8	-0.7	-2.0	-1.8	-1.6	-2.2	-1.9	-1.9	-1.9	-1.4	-2.3	-1.8	-1.2	-1.7	-1.9	-1.5	-1.9	-1.9	-1.9	-1.7
Alcohol intake versus 10 years previously	2.5	3.8	6.1	1.9	1.8	2.5	2.0	2.0	1.4	2.0	2.1	1.3	2.2	1.0	2.0	2.1	2.3	2.2	2.5	1.1	1.6	1.7	2.2	2.2	2.0	2.2	1.6
Coronary Artery Disease (CAD)	2.4	2.9	8.6	-2.4	-1.9	-0.7	-1.6	-1.7	1.9	-1.9	-1.5	-2.1	-1.6	-2.9	-1.8	-1.5	0.1	-1.8	-0.3	-1.4	-2.1	-2.3	-0.1	-0.9	-1.8	-1.3	-1.8
Medication: Bendroflumethiazide	2.4	3.7	6.4	1.5	1.9	2.5	1.9	1.8	0.3	2.0	2.0	1.7	2.4	1.1	1.8	2.0	2.3	2.2	2.5	0.9	1.8	1.8	2.5	1.9	1.8	2.1	1.5
Ever had prostate specific antigen (PSA) test	2.4	2.8	5.5	-2.1	-1.6	-2.0	-1.6	-1.7	-1.7	-1.6	-1.7	-1.4	-1.5	-0.7	-1.6	-1.7	-2.3	-1.1	-2.1	-2.2	-1.6	-1.6	-1.8	-1.5	-1.6	-1.7	-0.8
Pack years adult smoking proportion	2.3	3.5	10.7	-0.5	-1.3	-2.5	-1.4	-1.3	-3.3	-1.4	-1.7	-1.0	-2.4	-0.2	-1.3	-1.6	-2.4	-1.8	-2.6	-1.4	-1.2	-2.1	-3.2	-2.6	-1.3	-1.6	-0.3
Medication: Seretide 50 evohaler	2.3	2.6	9.2	-1.6	-1.4	-2.1	-1.4	-1.1	0.2	-1.4	-1.5	-1.5	-2.5	-0.9	-1.1	-1.4	-1.9	-2.1	-2.2	-0.1	-1.4	-1.6	-3.0	-1.9	-1.1	-1.5	-0.8
Severe depression (siblings)	2.2	2.4	6.0	-1.2	-1.9	-1.3	-1.7	-1.6	-0.2	-1.7	-1.5	-2.2	-2.0	-2.4	-1.6	-1.5	-0.9	-1.3	-1.2	-1.2	-2.1	-1.8	-0.9	-0.0	-1.6	-1.5	-1.6
Stomach or abdominal pain in last month	2.2	2.8	5.6	-0.4	-1.8	-1.4	-1.7	-1.6	0.8	-1.8	-1.7	-2.0	-2.0	-2.3	-1.7	-1.6	-0.9	-2.4	-1.2	-1.0	-1.9	-1.6	-1.7	-1.7	-1.7	-1.7	-2.1
Hair/balding pattern: Pattern 2	2.2	2.8	4.8	1.9	1.7	1.9	1.8	2.0	0.8	1.7	1.8	1.3	1.4	1.2	1.9	1.9	1.9	2.0	1.9	0.7	1.5	0.6	1.0	1.7	1.9	2.0	2.2
Average weekly red wine intake	2.2	3.3	6.7	-0.6	-1.4	-2.1	-2.0	-2.1	-0.2	-2.0	-2.1	-0.7	-1.5	-1.1	-2.1	-2.1	-1.9	-1.7	-2.1	-2.5	-1.2	-1.9	-1.8	-2.6	-2.1	-2.0	-1.3
Bilateral oophorectomy (both ovaries removed)	2.1	2.4	4.1	-0.3	-1.4	-1.5	-1.7	-1.7	-2.0	-1.6	-1.7	-1.2	-1.2	-0.8	-1.7	-1.7	-1.9	-1.3	-1.5	-1.8	-1.4	-1.4	-1.6	-1.8	-1.7	-1.6	-1.5
Tinnitus: Yes, but not now, but have in the past	2.1	2.3	4.0	-1.6	-1.7	-1.1	-1.6	-1.5	1.0	-1.6	-1.5	-2.0	-1.9	-2.0	-1.6	-1.5	-0.8	-1.6	-0.9	-1.1	-1.9	-1.7	-1.0	-0.8	-1.6	-1.4	-2.0
Forced expiratory volume in 1-second (FEV1)	2.1	7.1	15.4	-3.2	-2.9	-2.6	-2.8	-3.0	1.7	-3.2	-2.8	-2.4	-2.6	-3.9	-3.0	-2.9	-1.7	-3.1	-2.4	-1.5	-2.6	-2.3	-1.2	-1.6	-3.0	-3.0	-2.9
Migraine (self-reported)	2.1	2.7	5.4	-1.5	-1.7	-1.7	-1.5	-1.5	0.1	-1.5	-1.7	-2.1	-1.9	-1.0	-1.6	-1.6	-1.5	-1.9	-1.7	-1.2	-2.0	-1.5	-2.3	-1.8	-1.6	-1.6	-1.2
Medication for cholesterol	2.1	3.2	5.4	-0.9	-1.7	-2.3	-2.0	-2.0	-0.6	-2.0	-2.1	-0.9	-1.9	-1.3	-2.0	-2.1	-2.1	-1.9	-2.3	-0.8	-1.3	-1.3	-1.6	-1.8	-2.0	-2.2	-1.7
Father’s age at death	2.0	2.6	5.9	2.4	1.9	1.2	1.3	1.5	0.3	1.6	1.5	2.2	1.8	1.9	1.6	1.5	0.9	1.9	1.1	1.6	2.1	2.3	1.2	1.4	1.6	1.3	1.2
Medication for cholesterol, blood pressure or diabetes	2.0	3.4	5.1	-1.8	-2.0	-2.0	-1.8	-1.8	-0.7	-1.9	-1.9	-2.3	-2.2	-1.6	-1.8	-1.9	-2.0	-2.1	-2.0	-0.8	-2.2	-1.6	-1.9	-1.4	-1.8	-1.9	-1.9
Number of full brothers	2.0	2.5	7.2	-1.0	-1.2	-1.9	-1.6	-1.6	0.1	-1.7	-1.7	-0.6	-1.5	-0.7	-1.6	-1.7	-1.8	-1.9	-2.0	-1.4	-0.9	-1.6	-1.9	-2.7	-1.6	-1.7	-1.1
Handedness (chirality/laterality): Left-handed	2.0	2.4	6.1	-0.5	-1.3	-2.0	-1.6	-1.6	-1.1	-1.6	-1.9	-0.5	-1.4	-0.3	-1.6	-1.7	-2.3	-1.2	-2.1	-1.1	-0.9	-1.2	-2.5	-1.8	-1.6	-1.8	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	2.0	2.1	6.0	1.3	1.3	1.3	1.7	1.8	1.1	1.6	1.7	0.6	0.8	0.5	1.8	1.7	1.6	0.8	1.3	2.5	1.0	1.7	1.0	1.7	1.8	1.6	1.2
Back pain experienced in last month	2.0	2.9	6.0	2.1	1.5	1.8	2.0	2.0	1.2	1.9	1.8	0.6	1.4	1.1	2.0	2.0	1.6	2.2	1.7	0.5	1.1	0.8	1.0	2.3	2.0	2.0	2.5
Medication: Lisinopril	2.0	2.6	5.6	1.5	1.8	1.8	1.5	1.8	1.7	1.8	1.6	1.7	1.6	1.9	1.8	1.8	1.6	1.6	1.7	-0.1	1.7	0.5	0.7	0.4	1.8	2.0	2.4
Pack years of smoking	2.0	2.9	14.5	0.1	-1.1	-2.2	-1.2	-1.1	-3.8	-1.2	-1.5	-0.8	-2.0	0.1	-1.1	-1.4	-2.3	-1.5	-2.4	-1.1	-1.0	-1.6	-2.8	-2.4	-1.1	-1.4	-0.2
Mouth/teeth dental problems: Dentures	1.9	3.2	6.9	-0.6	-1.7	-2.1	-1.8	-1.8	-1.6	-1.9	-2.0	-1.8	-1.7	-0.9	-1.8	-1.9	-2.5	-1.4	-2.2	-1.5	-1.9	-1.2	-2.6	-1.4	-1.8	-2.0	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.9	6.1	10.6	-3.0	-2.5	-2.7	-2.6	-2.8	1.9	-3.0	-2.6	-1.7	-2.5	-3.3	-2.7	-2.8	-1.7	-2.9	-2.5	-1.3	-2.0	-2.0	-1.4	-1.9	-2.7	-2.9	-2.6
Eye problems/disorders: Cataract	1.9	2.2	4.6	1.5	1.4	1.9	1.3	1.2	-1.9	1.5	1.4	1.1	1.6	1.0	1.2	1.4	1.6	1.4	1.9	1.5	1.2	1.8	2.1	1.8	1.2	1.4	0.3
Guilty feelings	1.9	2.8	4.8	0.5	-1.8	-1.7	-1.8	-1.8	-1.2	-1.7	-1.8	-1.7	-2.0	-1.8	-1.8	-1.8	-1.4	-1.9	-1.6	-1.2	-1.8	-1.5	-1.1	-1.3	-1.8	-1.8	-2.2
Pain type(s) experienced in last month: Hip pain	1.9	2.4	4.1	1.3	1.3	1.7	1.8	1.8	0.7	1.7	1.8	0.4	1.4	0.9	1.8	1.8	1.4	1.4	1.6	1.6	0.9	1.6	1.5	2.0	1.8	1.8	1.7
High cholesterol (Self-reported)	1.9	3.4	5.0	2.0	1.9	2.0	1.9	1.9	-0.3	2.1	2.0	1.8	2.2	2.2	2.0	2.0	1.7	1.7	1.9	1.5	1.9	2.2	1.4	1.1	2.0	2.0	1.6
Chronotype (morning person)	1.8	4.1	9.4	2.0	2.2	2.1	1.7	1.4	0.6	2.0	1.9	3.0	3.1	2.4	1.5	1.7	1.6	2.8	2.0	0.1	2.6	1.9	3.0	1.4	1.5	1.8	1.7
Medication: Metformin	1.8	2.6	4.3	1.1	1.3	1.8	1.9	2.0	2.1	1.7	1.9	0.4	0.9	0.4	1.9	1.9	1.9	0.9	1.7	1.9	0.9	1.3	1.1	1.7	1.9	1.9	1.8
Diabetes (mother)	1.8	2.3	9.8	-1.4	-1.3	-1.7	-1.5	-1.6	-1.0	-1.5	-1.6	-0.6	-1.1	-0.4	-1.6	-1.6	-2.0	-0.6	-1.8	-3.1	-1.0	-1.9	-1.8	-1.7	-1.6	-1.5	-0.5
High blood pressure (mother)	1.8	2.6	5.6	-1.2	-1.7	-1.5	-1.7	-1.9	0.4	-1.6	-1.8	-1.5	-1.7	-1.2	-1.9	-1.8	-1.2	-1.9	-1.4	-1.3	-1.7	-1.2	-1.1	-1.7	-1.9	-1.8	-2.4
Diabetes (self-reported)	1.8	2.8	4.5	2.0	1.5	1.7	2.0	2.1	1.0	1.9	2.0	0.6	1.1	0.9	2.1	2.0	1.6	1.5	1.6	1.7	1.1	1.4	1.0	1.8	2.1	2.0	2.1
Weight	1.8	9.0	16.0	1.2	2.7	3.5	3.5	3.1	2.4	3.1	3.5	1.7	2.7	1.0	3.1	3.2	3.8	2.1	3.6	3.8	2.3	3.5	4.0	3.5	3.1	3.1	1.5
Worry too long after embarrassment	1.8	3.0	9.5	-1.9	-2.2	-1.1	-1.6	-1.6	-0.9	-1.9	-1.5	-2.5	-2.2	-3.1	-1.7	-1.6	-0.5	-2.0	-0.9	-1.0	-2.3	-2.2	-0.4	-0.4	-1.7	-1.5	-1.8
Qualifications: nursing, teaching	1.8	2.7	5.6	-1.0	-1.4	-1.8	-1.9	-1.6	-2.0	-1.6	-1.8	-1.0	-1.7	-0.6	-1.7	-1.7	-1.8	-1.3	-1.8	-2.4	-1.3	-2.1	-1.8	-2.0	-1.7	-1.5	-1.0
Financial situation satisfaction	1.8	2.2	4.2	-1.4	-1.8	-1.4	-1.4	-1.6	-1.6	-1.6	-1.4	-2.0	-1.3	-1.9	-1.6	-1.6	-1.5	-1.5	-1.3	-1.0	-2.0	-1.1	-0.5	-0.6	-1.6	-1.6	-1.1
Illnesses of father: High blood pressure	1.8	2.2	4.4	-1.9	-1.5	-1.0	-1.6	-1.7	0.3	-1.8	-1.5	-1.4	-1.3	-2.1	-1.7	-1.5	-0.6	-2.1	-0.8	-0.7	-1.5	-1.4	-0.8	-1.5	-1.7	-1.5	-1.6
Neuroticism (2016)	1.7	2.4	5.1	-0.8	-1.8	-1.5	-1.6	-1.4	0.0	-1.4	-1.4	-2.2	-2.2	-1.5	-1.4	-1.4	-1.4	-2.1	-1.5	-0.7	-2.0	-1.8	-1.4	-1.3	-1.4	-1.4	-1.8
Systolic Blood Pressure	1.7	8.4	13.6	-3.5	-3.0	-2.2	-3.3	-3.3	-2.0	-3.3	-3.1	-2.6	-2.6	-3.1	-3.3	-3.1	-2.1	-2.6	-2.1	-3.3	-3.0	-3.7	-1.7	-2.3	-3.3	-2.9	-2.8
Smoking Status	1.7	4.0	7.7	-0.6	-2.0	-2.4	-1.8	-1.8	0.7	-2.2	-2.0	-2.4	-2.8	-2.4	-1.8	-1.9	-2.1	-2.1	-2.4	-0.9	-2.2	-1.9	-2.6	-1.0	-1.8	-2.1	-1.8
Current tobacco smoking	1.7	2.8	5.5	-0.5	-1.7	-2.1	-1.4	-1.4	-1.7	-1.7	-1.5	-1.9	-2.4	-1.6	-1.4	-1.5	-2.1	-1.7	-2.2	-1.2	-1.8	-2.1	-2.1	-1.1	-1.4	-1.6	-0.9
Hearing difficulty/problems with background noise	1.7	2.8	9.1	1.2	1.2	2.6	1.6	1.5	2.1	1.6	1.8	-0.0	1.1	-0.5	1.5	1.8	3.0	0.6	2.8	1.5	0.5	1.3	2.3	1.6	1.5	1.8	0.5
Qualifications: A levels/AS levels or equivalent	1.7	3.8	8.9	-0.7	-1.7	-2.4	-2.3	-1.9	-1.6	-1.9	-2.4	-1.1	-2.2	-1.0	-2.0	-2.1	-2.0	-1.5	-2.3	-2.2	-1.4	-2.0	-3.0	-2.2	-2.0	-2.1	-1.7
Impedance of arm (left)	1.7	7.8	12.2	-2.7	-3.0	-2.7	-3.1	-2.9	-0.7	-3.3	-3.0	-3.0	-3.3	-3.5	-2.9	-2.8	-2.4	-2.6	-2.6	-2.1	-3.0	-3.3	-2.8	-1.8	-2.9	-2.9	-2.4
Number of children fathered	1.7	1.9	6.7	0.1	-1.0	-1.7	-1.5	-1.2	-2.1	-1.0	-1.5	-0.4	-1.1	0.5	-1.1	-1.3	-2.1	-0.5	-1.8	-1.9	-0.7	-1.2	-2.6	-1.8	-1.1	-1.2	-0.4
Commuting to job workplace: Public transport	1.7	2.0	5.0	-0.7	-1.4	-1.4	-1.5	-1.6	-1.3	-1.6	-1.5	-1.0	-1.3	-1.0	-1.6	-1.6	-1.3	-2.2	-1.3	-0.5	-1.2	-1.2	-1.0	-2.2	-1.6	-1.6	-1.3
Verbal and Numeric Reasoning (VNR)	1.6	3.8	13.1	-1.4	-1.6	-2.6	-1.9	-1.5	-0.0	-1.6	-2.1	-0.9	-2.7	-0.6	-1.6	-1.8	-2.1	-1.3	-2.6	-2.7	-1.2	-2.7	-3.6	-2.6	-1.6	-1.7	-0.6
Illnesses of siblings	1.6	2.2	6.1	1.6	1.1	1.4	1.4	1.4	-1.1	1.7	1.4	0.8	1.9	1.4	1.4	1.4	0.8	1.9	1.2	1.6	1.1	2.5	1.6	2.1	1.4	1.3	0.9
Depression (self-reported)	1.6	1.9	5.3	-1.1	-1.3	-1.4	-1.5	-1.3	0.9	-1.1	-1.5	-1.0	-1.7	-0.8	-1.3	-1.4	-1.0	-1.7	-1.4	-1.0	-1.2	-1.0	-1.9	-2.3	-1.3	-1.4	-1.4
Arm predicted mass (right)	1.6	8.4	13.6	2.0	2.8	3.2	3.3	3.0	3.1	3.0	3.2	2.0	2.8	1.4	3.0	3.0	3.7	1.9	3.3	3.5	2.5	3.5	3.6	2.9	3.0	2.9	1.5
Diastolic blood pressure, automated reading	1.6	5.0	9.4	-2.8	-2.5	-1.6	-2.3	-2.3	-2.1	-2.3	-2.3	-2.7	-2.1	-2.3	-2.3	-2.1	-1.6	-1.8	-1.5	-3.1	-2.7	-2.9	-1.9	-1.9	-2.3	-2.0	-1.8
Hearing difficulty/problems: Yes	1.5	2.3	6.2	-0.1	1.5	2.2	1.4	1.6	1.6	1.5	1.6	0.8	1.2	0.1	1.6	1.8	2.5	1.3	2.3	1.1	1.1	0.9	1.5	1.7	1.6	1.8	1.0
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	5.5	-0.8	-1.4	-1.7	-1.5	-1.3	0.5	-1.5	-1.6	-1.1	-1.9	-1.0	-1.3	-1.5	-1.4	-2.3	-1.7	-0.1	-1.2	-1.0	-2.4	-2.2	-1.3	-1.6	-1.6
Mouth/teeth dental problems	1.5	2.4	7.2	0.4	1.4	2.0	1.5	1.4	1.5	1.5	1.7	1.3	1.6	0.5	1.4	1.6	2.4	1.5	2.1	0.4	1.4	0.8	2.7	1.3	1.4	1.7	0.8
Asthma	1.5	3.0	6.9	-0.6	-1.4	-2.1	-1.8	-1.7	-0.2	-2.0	-1.8	-0.9	-2.1	-1.5	-1.7	-1.8	-1.7	-2.6	-2.0	-0.4	-1.2	-1.7	-2.3	-2.6	-1.7	-1.9	-1.7
Hair/balding pattern: Pattern 4	1.5	3.6	7.4	-2.6	-2.1	-1.9	-1.5	-1.8	-2.7	-1.9	-1.7	-2.1	-1.8	-1.3	-1.8	-1.8	-2.4	-1.0	-2.0	-2.3	-2.2	-2.5	-1.5	-0.7	-1.8	-1.6	-0.5
Emphysema/chronic bronchitis	1.5	1.7	4.3	-0.9	-1.3	-1.4	-1.2	-1.1	-0.0	-1.4	-1.3	-1.4	-1.9	-1.3	-1.1	-1.2	-1.3	-1.6	-1.4	-0.6	-1.3	-1.6	-2.1	-1.5	-1.1	-1.2	-1.1
Medication: Gliclazide	1.5	1.7	3.0	1.6	1.3	1.5	1.4	1.5	1.1	1.3	1.4	0.9	1.2	0.5	1.5	1.5	1.7	0.5	1.6	1.5	1.1	1.2	1.0	0.6	1.5	1.5	1.3
Cholesterol lowering medication	1.5	2.2	3.3	0.8	1.4	1.7	1.7	1.7	-0.3	1.8	1.7	0.9	1.5	1.6	1.7	1.7	1.2	1.3	1.5	1.8	1.2	1.8	1.0	1.4	1.7	1.7	1.2
Irritable Bowel Disease (IBD)	1.4	3.4	7.8	-1.9	-2.1	-1.6	-2.1	-1.8	-1.0	-1.9	-1.7	-2.2	-2.2	-1.8	-1.7	-1.7	-1.7	-0.9	-1.6	-2.8	-2.2	-2.8	-1.4	-0.6	-1.7	-1.5	-1.3
Breast Cancer	1.4	3.4	8.1	1.6	1.8	2.1	1.8	1.8	-0.6	1.9	1.9	1.7	2.1	1.8	1.8	1.9	1.9	2.9	2.1	0.0	1.7	0.9	1.9	2.0	1.8	2.1	2.4
Blood White Count	1.4	10.6	17.0	1.7	3.7	3.3	3.7	3.8	0.8	3.5	3.7	3.2	3.0	2.9	3.7	3.7	3.1	3.5	3.2	2.5	3.5	2.2	2.8	2.9	3.7	3.8	4.1
Medication: Levothyroxine sodium	1.4	2.4	6.0	1.4	1.5	1.5	1.4	1.4	-1.1	1.8	1.5	1.8	2.2	2.4	1.4	1.4	1.0	2.4	1.4	-0.2	1.7	1.6	1.5	1.2	1.4	1.5	1.3
Qualifications: None of the above	1.4	3.0	6.1	1.8	1.3	1.8	2.4	2.1	1.0	2.0	2.2	0.4	1.3	1.3	2.1	2.1	1.6	0.5	1.7	2.5	1.0	1.8	1.2	0.9	2.1	2.0	1.9
Falls in the last year	1.4	1.9	5.8	-2.0	-1.4	-1.4	-0.9	-0.9	-0.5	-1.1	-1.2	-1.7	-2.0	-0.3	-1.0	-1.1	-1.5	-1.7	-1.4	-0.2	-1.6	-1.4	-2.4	-1.5	-1.0	-1.1	-1.0
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	7.7	0.9	1.3	1.7	1.6	1.5	-1.1	1.8	1.6	1.2	2.4	2.0	1.5	1.5	1.0	2.8	1.6	0.3	1.3	2.0	1.7	2.3	1.5	1.6	1.4
High blood pressure (siblings)	1.4	2.1	3.4	-1.2	-1.1	-1.5	-1.6	-1.6	0.8	-1.8	-1.6	-0.5	-1.7	-1.5	-1.6	-1.6	-1.0	-1.9	-1.4	-0.8	-0.9	-1.6	-1.7	-1.7	-1.6	-1.6	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	4.8	-0.6	-1.3	-0.9	-1.3	-1.4	0.4	-1.4	-1.4	-1.2	-1.5	-1.9	-1.5	-1.4	-0.3	-1.4	-0.7	-1.0	-1.3	-1.1	-0.3	-0.7	-1.5	-1.4	-2.2
Commuting to job workplace: Cycle	1.4	1.7	4.3	-0.5	-1.1	-1.6	-1.5	-1.4	-1.2	-1.3	-1.5	-0.7	-1.1	-0.2	-1.4	-1.5	-2.1	-0.9	-1.7	-0.6	-0.9	-0.8	-1.5	-1.2	-1.4	-1.5	-1.3
Average weekly spirits intake	1.3	1.6	2.5	-0.9	-1.3	-1.0	-1.3	-1.4	0.2	-1.5	-1.3	-1.2	-1.3	-1.5	-1.4	-1.3	-0.5	-1.6	-0.8	-1.1	-1.3	-1.5	-0.9	-1.4	-1.4	-1.3	-1.6
Had menopause	1.3	1.6	3.6	1.8	0.9	1.7	1.0	1.2	-0.3	1.1	1.3	-0.0	1.0	0.1	1.2	1.3	1.9	0.8	1.9	1.7	0.4	1.2	1.6	1.8	1.2	1.3	0.1
Financial difficulties in last 2 years	1.3	1.8	3.7	-0.4	-1.4	-1.5	-1.3	-1.3	-0.7	-1.2	-1.4	-1.3	-1.5	-0.8	-1.3	-1.3	-1.4	-1.9	-1.5	-1.0	-1.4	-0.9	-1.9	-1.9	-1.3	-1.4	-1.0
Qualifications: College or University degree	1.3	4.1	8.9	-1.3	-2.1	-1.9	-2.3	-2.1	-2.6	-2.1	-2.1	-1.8	-2.0	-1.6	-2.1	-2.1	-2.1	-1.0	-1.9	-3.0	-2.0	-2.6	-1.5	-1.1	-2.1	-1.9	-1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.6	4.0	0.0	-1.6	-1.3	-1.2	-1.3	-0.5	-1.3	-1.4	-2.0	-1.1	-1.1	-1.2	-1.3	-1.6	-1.1	-1.4	-1.0	-1.8	-1.2	-1.6	-0.6	-1.2	-1.3	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.6	5.3	-1.2	-1.8	-1.7	-1.5	-1.4	1.5	-1.7	-1.5	-1.9	-2.3	-2.2	-1.4	-1.5	-1.2	-2.1	-1.6	-0.1	-1.8	-1.4	-1.9	-1.0	-1.4	-1.6	-1.9
Diabetes diagnosed by doctor	1.3	2.2	3.9	2.0	1.2	1.6	1.8	1.8	1.4	1.6	1.7	0.3	1.0	0.6	1.8	1.7	1.6	1.1	1.5	1.5	0.8	1.3	1.1	1.6	1.8	1.7	1.7
Pain experienced in last month	1.3	2.2	5.0	-2.0	-1.1	-1.4	-1.9	-1.8	-0.8	-1.7	-1.7	0.1	-1.0	-0.7	-1.8	-1.7	-1.2	-1.6	-1.3	-1.3	-0.5	-1.4	-0.8	-2.2	-1.8	-1.7	-1.8
Neuroticism (Nagel 2018)	1.2	2.9	4.6	-1.7	-1.8	-1.7	-1.9	-1.8	-0.6	-1.8	-1.8	-1.7	-2.1	-1.6	-1.8	-1.8	-1.2	-2.1	-1.6	-1.0	-1.8	-1.6	-1.4	-1.5	-1.8	-1.8	-2.1
Hypothyroidism (self reported)	1.2	2.7	7.2	0.3	1.3	1.7	1.6	1.6	-0.9	1.8	1.6	1.1	2.2	2.1	1.6	1.6	0.8	2.7	1.5	0.6	1.3	1.8	1.4	2.4	1.6	1.7	1.7
Neuroticism score	1.2	2.5	6.0	-2.4	-1.9	-1.0	-1.5	-1.5	0.1	-1.7	-1.4	-2.1	-1.9	-2.5	-1.6	-1.5	-0.4	-2.0	-0.8	-0.7	-2.0	-1.7	-0.4	-0.7	-1.6	-1.4	-1.9
Gout (self-reported)	1.2	1.7	3.5	0.8	1.4	1.3	1.4	1.5	0.2	1.4	1.4	1.1	0.9	0.9	1.5	1.5	1.1	1.8	1.3	0.9	1.2	0.7	1.1	1.9	1.5	1.6	1.7
Arm fat-free mass (right)	1.2	6.4	12.2	1.6	2.3	2.8	2.8	2.5	3.4	2.5	2.8	1.6	2.4	0.6	2.4	2.6	3.4	1.4	3.0	3.1	2.0	3.0	3.5	2.7	2.4	2.4	1.0
Asthma (self-reported)	1.2	2.4	5.6	-0.4	-1.2	-1.8	-1.6	-1.5	-0.3	-1.7	-1.6	-0.8	-1.8	-1.3	-1.5	-1.6	-1.5	-2.4	-1.8	-0.2	-1.0	-1.3	-2.0	-2.3	-1.5	-1.7	-1.6
Ever taken oral contraceptive pill	1.2	1.4	3.0	-0.6	-1.1	-1.2	-1.2	-1.3	0.3	-1.4	-1.2	-0.8	-1.5	-1.7	-1.3	-1.3	-0.6	-1.3	-1.0	-1.1	-1.0	-1.5	-0.7	-1.0	-1.3	-1.3	-1.1
Fractured/broken bones in last 5 years	1.2	1.5	3.8	-0.2	-1.2	-1.4	-1.3	-1.3	-0.9	-1.4	-1.4	-0.9	-1.1	-0.7	-1.2	-1.3	-1.4	-1.3	-1.4	-1.1	-1.0	-1.2	-2.0	-1.7	-1.2	-1.3	-0.3
Medication: Omeprazole (e.g. Zanprol)	1.2	1.5	3.6	1.9	1.1	1.4	1.3	1.2	-0.5	1.4	1.3	0.8	1.1	1.5	1.2	1.3	0.9	0.7	1.3	1.7	1.0	1.5	1.0	0.7	1.2	1.3	0.5
Impedance of whole body	1.2	6.3	8.6	-2.2	-2.6	-2.7	-2.8	-2.6	-1.3	-2.9	-2.7	-2.3	-2.9	-2.6	-2.6	-2.6	-2.5	-2.3	-2.7	-2.0	-2.5	-2.8	-2.9	-1.9	-2.6	-2.7	-1.8
Bipolar Disorder or Schizophrenia	1.1	2.6	7.0	1.0	1.6	2.1	1.5	1.3	0.7	1.5	1.7	1.6	2.2	1.0	1.4	1.6	2.0	1.8	2.2	0.6	1.5	1.4	2.6	1.9	1.4	1.7	1.0
Crohns Disease (2017)	1.1	2.5	4.5	-2.1	-1.5	-1.6	-1.7	-1.5	-1.3	-1.6	-1.6	-1.3	-1.7	-1.0	-1.5	-1.5	-1.8	-1.1	-1.7	-2.0	-1.5	-2.1	-1.6	-1.4	-1.5	-1.4	-0.8
Triglycerides	1.1	1.8	3.3	1.0	1.3	1.8	1.6	1.5	0.6	1.2	1.6	0.8	1.3	0.7	1.4	1.5	1.4	1.4	1.7	0.6	0.9	0.2	1.7	1.5	1.4	1.7	1.8
Impedance of leg (right)	1.1	5.5	8.4	-2.0	-2.2	-2.8	-2.7	-2.5	-1.2	-2.6	-2.7	-1.6	-2.5	-1.8	-2.5	-2.6	-2.5	-2.4	-2.7	-1.8	-1.9	-2.4	-2.9	-2.6	-2.5	-2.6	-1.7
Fluid intelligence score	1.1	2.3	8.7	-1.3	-1.2	-1.9	-1.5	-1.1	-1.0	-1.2	-1.6	-0.9	-1.9	-0.2	-1.1	-1.3	-1.9	-0.4	-2.0	-2.2	-1.0	-2.2	-2.9	-1.3	-1.1	-1.2	0.1
Pulse wave reflection index	1.1	1.3	6.5	0.7	1.1	1.0	1.0	1.1	2.5	0.9	1.0	1.0	0.9	0.2	1.1	1.1	1.3	0.8	1.1	1.8	1.1	1.2	1.0	1.3	1.1	0.9	0.6
Glaucoma (self-reported)	1.1	1.3	2.1	-0.3	-1.3	-0.9	-1.2	-1.5	-1.2	-1.4	-1.3	-1.1	-0.5	-1.3	-1.5	-1.3	-0.7	-0.8	-0.7	-1.4	-1.2	-0.8	-0.2	-0.5	-1.5	-1.3	-1.4
Angina (self-reported)	1.1	1.4	3.9	2.0	1.1	1.0	1.3	1.2	-0.3	1.3	1.1	0.7	1.1	1.3	1.2	1.2	0.5	1.3	0.8	1.7	0.9	1.7	0.6	1.6	1.2	1.1	0.9
Comparative height size at age 10	1.1	6.0	15.4	1.7	2.1	2.7	2.6	2.4	2.4	2.0	2.7	1.3	2.2	-0.1	2.3	2.4	3.3	1.3	2.9	3.9	1.8	2.9	3.5	3.3	2.3	2.2	0.8
Risk taking	1.1	1.6	7.1	1.0	1.0	1.4	1.5	1.3	1.8	1.2	1.3	0.4	0.9	0.5	1.3	1.3	1.3	-0.1	1.4	2.7	0.8	1.8	0.9	0.8	1.3	1.2	0.5
Arm predicted mass (left)	1.1	5.8	11.0	1.4	2.2	2.6	2.8	2.4	2.7	2.4	2.7	1.6	2.2	0.8	2.4	2.5	3.2	1.4	2.8	3.1	1.9	2.9	3.3	2.5	2.4	2.4	1.0
Blood Red Count	1.0	9.2	13.8	0.6	3.1	3.4	3.5	3.6	-0.8	3.6	3.6	2.5	2.9	3.5	3.6	3.6	2.6	3.1	3.2	2.4	2.8	2.5	2.4	2.4	3.6	3.7	3.4
Neuroticism	1.0	2.3	4.6	-2.1	-1.8	-1.4	-1.5	-1.5	-0.2	-1.6	-1.4	-1.9	-1.9	-1.7	-1.6	-1.5	-1.0	-1.9	-1.3	-0.9	-1.9	-1.7	-0.8	-0.8	-1.6	-1.5	-1.7
Angina	1.0	1.3	3.7	1.9	1.1	1.0	1.3	1.2	0.1	1.2	1.2	0.7	1.0	1.2	1.2	1.2	0.6	1.2	0.8	1.6	0.9	1.6	0.7	1.5	1.2	1.1	1.0
Leg fat-free mass (left)	1.0	5.4	12.6	0.7	1.8	2.7	2.5	2.2	2.9	2.1	2.6	0.9	1.9	-0.0	2.2	2.4	3.3	1.2	2.9	3.2	1.4	2.6	3.5	3.1	2.2	2.2	0.5
Impedance of leg (left)	1.0	5.0	8.6	-1.6	-2.1	-2.7	-2.5	-2.3	-1.6	-2.5	-2.5	-1.4	-2.4	-1.6	-2.3	-2.4	-2.5	-2.0	-2.8	-2.0	-1.8	-2.2	-2.9	-2.3	-2.3	-2.5	-1.4
Leg predicted mass (left)	1.0	5.6	13.0	0.8	1.8	2.8	2.6	2.3	2.9	2.2	2.6	0.9	1.9	-0.0	2.3	2.4	3.3	1.3	3.0	3.3	1.4	2.6	3.6	3.1	2.3	2.3	0.5
Worrier / anxious feelings	1.0	1.9	3.3	-1.8	-1.5	-1.5	-1.3	-1.4	0.2	-1.5	-1.4	-1.3	-1.7	-1.4	-1.4	-1.5	-1.1	-1.8	-1.4	-0.8	-1.4	-1.6	-1.0	-1.4	-1.4	-1.5	-1.1
Illnesses of mother	1.0	1.2	4.2	1.1	1.0	0.5	1.1	1.2	-1.0	1.1	1.0	1.0	1.1	1.4	1.2	1.1	-0.1	1.9	0.3	0.2	1.1	0.8	0.3	1.2	1.2	1.0	2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	4.1	-1.0	-1.4	-1.1	-1.1	-1.2	0.3	-1.4	-1.1	-1.4	-1.5	-2.0	-1.3	-1.2	-0.5	-1.5	-0.9	-1.2	-1.5	-1.5	-0.5	-0.9	-1.3	-1.2	-1.1
Neck or shoulder pain in last month	1.0	1.4	6.7	2.6	1.1	0.7	1.2	1.3	0.7	1.4	1.1	0.8	1.0	1.4	1.3	1.2	0.5	0.9	0.6	1.3	1.0	1.6	0.2	0.7	1.3	1.0	1.1
Medication: Blood pressure	1.0	1.9	3.7	0.7	1.3	1.9	1.5	1.5	0.3	1.6	1.6	0.7	1.6	1.1	1.6	1.7	1.6	1.3	1.9	0.7	1.0	1.2	1.1	1.1	1.6	1.7	1.1
Arm fat-free mass (left)	1.0	5.2	10.8	1.2	2.0	2.5	2.6	2.3	2.6	2.2	2.6	1.3	2.0	0.5	2.2	2.3	3.1	1.2	2.7	3.0	1.7	2.7	3.3	2.6	2.2	2.2	0.7
HbA1C	0.9	1.0	3.4	1.8	1.2	0.4	0.5	0.9	-0.6	0.8	0.4	1.7	1.3	1.6	0.5	0.5	0.6	0.6	0.8	1.3	1.4	1.8	0.3	-0.4	0.5	0.4	0.2
Schizophrenia (2014)	0.9	2.1	6.5	0.6	1.2	1.8	1.4	1.2	0.3	1.4	1.5	1.2	1.9	0.9	1.2	1.4	1.7	1.7	1.8	0.6	1.2	1.2	2.5	2.0	1.2	1.5	1.0
Medication: Atenolol	0.9	1.1	2.1	0.7	0.9	1.4	1.2	1.1	0.5	1.2	1.2	0.3	1.2	0.7	1.1	1.2	1.3	1.2	1.4	0.3	0.6	0.8	1.3	1.1	1.1	1.3	1.2
Noisy workplace	0.9	1.2	2.6	-1.6	-1.4	-1.0	-1.0	-0.8	0.2	-1.1	-0.9	-1.6	-1.0	-1.1	-0.8	-0.9	-1.4	-0.5	-1.1	-1.5	-1.4	-1.4	-1.2	-0.2	-0.8	-0.8	0.0
Prospective memory result	0.9	1.1	4.7	1.1	0.9	0.8	1.0	1.0	0.4	1.1	1.0	0.4	0.9	0.9	1.1	1.1	0.7	0.8	0.7	2.2	0.7	2.0	0.5	1.7	1.1	0.8	0.3
Leg fat-free mass (right)	0.9	4.6	10.9	0.8	1.6	2.5	2.3	2.0	2.6	1.9	2.4	0.7	1.7	-0.2	2.0	2.2	3.0	1.2	2.7	3.0	1.2	2.5	3.3	3.1	2.0	2.0	0.4
Mineral and other dietary supplements	0.9	1.3	5.1	-1.9	-0.9	-1.0	-1.1	-1.1	-0.3	-1.0	-1.0	-0.2	-0.9	-0.8	-1.2	-1.1	-0.5	-0.9	-0.9	-2.3	-0.6	-1.9	-0.3	-1.6	-1.2	-0.9	-0.3
Hearing aid user	0.9	1.1	1.9	-0.4	-1.2	-0.9	-1.3	-1.0	-0.6	-1.0	-1.2	-1.3	-1.0	-0.7	-1.1	-1.0	-1.0	-0.3	-0.9	-1.4	-1.3	-1.2	-1.3	-0.2	-1.1	-1.0	-0.9
Bipolar Disorder (2018)	0.8	1.2	3.0	0.5	0.9	1.5	1.0	1.1	1.4	1.0	1.1	0.5	1.3	0.2	1.1	1.2	1.3	1.2	1.5	0.8	0.7	1.0	1.3	1.7	1.1	1.2	0.6
Schizophrenia (2018)	0.8	1.6	5.6	0.9	1.2	1.5	1.1	0.8	-0.3	1.2	1.2	1.6	1.8	1.1	0.9	1.1	1.5	1.3	1.6	0.2	1.4	1.0	2.4	1.0	0.9	1.2	0.8
Prostate Cancer	0.8	1.1	4.3	0.7	-0.3	-1.5	-0.7	-0.6	0.5	-0.8	-1.0	0.3	-1.4	-0.2	-0.7	-0.9	-1.1	-1.2	-1.6	-0.7	-0.0	-1.1	-2.1	-2.1	-0.7	-0.9	-0.2
Frequency of depressed mood in last 2 weeks	0.8	1.2	3.7	-0.6	-1.1	-0.9	-0.8	-0.7	0.4	-0.8	-0.9	-1.5	-1.9	-1.5	-0.7	-0.8	-0.4	-1.9	-0.8	0.5	-1.2	-0.7	-1.2	-1.0	-0.7	-0.9	-1.8
Ever had hysterectomy (womb removed)	0.8	1.0	1.7	-0.3	-1.0	-0.6	-1.1	-1.3	-1.1	-1.2	-1.0	-0.9	-0.3	-1.0	-1.3	-1.1	-0.5	-1.0	-0.5	-1.1	-1.1	-0.9	0.0	-1.0	-1.3	-1.1	-1.3
Serious illness, injury or assault to yourself	0.8	0.9	2.6	0.6	-0.9	-1.1	-0.8	-0.7	-0.0	-0.8	-0.9	-0.7	-1.5	-0.6	-0.7	-0.8	-1.0	-1.6	-1.2	0.3	-0.7	-0.6	-1.6	-1.3	-0.7	-1.0	-1.0
Had other major operations	0.8	1.0	2.8	-0.7	-1.0	-0.9	-1.0	-1.0	-1.2	-0.9	-1.0	-0.9	-1.0	-0.4	-1.0	-1.0	-0.8	-0.6	-0.9	-1.7	-1.0	-1.3	-1.3	-1.4	-1.0	-0.9	-0.7
Standing height	0.8	8.1	31.4	-2.6	-2.9	-2.1	-2.7	-2.7	3.5	-3.3	-2.5	-3.2	-3.3	-5.6	-2.7	-2.6	-0.3	-3.8	-1.6	0.6	-3.0	-1.5	-1.0	-0.7	-2.7	-3.0	-4.4
Exposure to tobacco smoke at home	0.8	0.9	2.6	-0.9	0.9	0.6	0.9	0.7	1.6	0.9	0.9	1.2	1.4	1.0	0.8	0.7	0.6	0.8	0.6	1.1	1.1	1.6	1.1	0.7	0.8	0.6	0.7
Shortness of breath walking on level ground	0.8	0.9	2.9	-1.1	-1.2	-0.5	-0.7	-0.8	-0.8	-0.8	-0.7	-1.7	-1.1	-1.5	-0.8	-0.8	-0.4	-1.3	-0.4	-0.1	-1.5	-0.7	-0.2	-0.2	-0.8	-0.8	-1.4
Leg pain on walking	0.8	1.0	4.9	1.1	0.5	0.7	1.1	1.1	0.7	1.0	1.1	-0.2	0.5	-0.0	1.1	1.1	0.8	0.3	0.7	2.2	0.3	2.0	0.6	1.4	1.1	0.7	0.3
Leg predicted mass (right)	0.8	4.5	10.7	0.8	1.6	2.4	2.3	2.0	2.7	1.9	2.3	0.7	1.7	-0.2	2.0	2.1	3.0	1.2	2.6	3.0	1.2	2.5	3.3	3.0	2.0	2.0	0.4
Basal metabolic rate	0.8	4.5	10.7	0.9	1.7	2.4	2.3	2.0	2.8	1.9	2.3	0.9	1.7	-0.0	2.0	2.1	3.0	0.9	2.6	3.0	1.4	2.5	3.3	2.6	2.0	1.9	0.3
Reaction Time	0.7	1.3	4.1	0.1	0.9	1.2	1.4	1.6	0.1	1.4	1.4	0.0	0.4	1.2	1.6	1.5	0.9	1.2	1.0	0.4	0.5	0.1	0.1	1.0	1.6	1.7	2.0
Crohns Disease (2012)	0.7	1.2	3.2	-0.3	-1.0	-1.3	-1.2	-1.0	-0.5	-1.1	-1.2	-0.9	-1.2	-0.5	-1.0	-1.0	-1.6	-1.0	-1.5	-1.0	-1.0	-1.3	-1.8	-1.2	-1.0	-1.1	-0.4
Lupus	0.7	1.0	2.0	-0.9	-1.1	-0.8	-1.1	-1.1	-0.6	-1.0	-1.0	-1.1	-1.1	-1.2	-1.1	-1.0	-0.7	-0.8	-0.8	-1.4	-1.2	-1.1	-0.9	-0.7	-1.1	-1.0	-1.3
Ulcerative Colitis	0.7	1.0	3.2	-0.7	-1.2	-0.7	-1.3	-0.8	-0.3	-0.7	-0.8	-1.7	-1.2	-0.9	-0.8	-0.8	-1.0	-0.2	-0.8	-1.8	-1.5	-1.4	-0.5	0.4	-0.8	-0.6	-0.8
Maternal smoking around birth	0.7	1.1	1.7	0.3	-1.1	-0.9	-1.0	-1.3	-0.6	-1.3	-1.2	-1.0	-0.7	-1.0	-1.3	-1.2	-0.8	-1.3	-0.9	-0.8	-1.1	-0.7	-0.6	-1.2	-1.3	-1.2	-0.9
Multivitamins +/- minerals	0.7	0.8	2.6	-0.4	-0.9	-0.8	-0.9	-0.8	0.5	-1.0	-0.9	-1.6	-1.1	-1.4	-0.8	-0.8	-0.6	-1.1	-0.7	-0.1	-1.4	-0.5	-1.2	-0.2	-0.8	-0.9	-1.0
Forced vital capacity (FVC)	0.7	2.6	7.1	-2.1	-1.7	-1.6	-1.6	-1.7	1.3	-2.0	-1.5	-1.5	-1.6	-2.7	-1.7	-1.7	-1.0	-2.1	-1.5	0.1	-1.5	-1.0	-0.6	-0.6	-1.7	-1.8	-1.8
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.4	-0.6	-0.7	-1.0	-0.6	-0.5	-1.0	-0.7	-0.7	-1.2	-1.2	-0.8	-0.5	-0.6	-0.8	-1.6	-1.0	0.8	-0.9	-0.2	-1.4	-0.9	-0.5	-0.8	-0.7
Breastfed as a baby	0.7	0.9	3.0	1.1	1.4	0.3	0.5	0.9	-0.1	0.9	0.7	1.7	0.9	1.4	0.8	0.7	0.3	0.7	0.2	1.5	1.5	1.7	0.4	0.2	0.8	0.5	0.4
Birth weight	0.7	1.4	3.1	-1.1	-0.9	-1.7	-1.2	-1.1	0.4	-1.2	-1.3	-0.5	-1.5	-0.7	-1.1	-1.2	-1.5	-1.4	-1.7	0.2	-0.7	-0.3	-1.8	-1.2	-1.1	-1.5	-1.5
Heart disease (mother)	0.7	0.8	2.2	-1.5	-1.0	-0.7	-1.0	-0.8	0.8	-0.9	-0.8	-1.2	-1.1	-1.2	-0.8	-0.8	-0.6	-0.8	-0.7	0.4	-1.1	-0.4	-0.9	0.2	-0.8	-0.9	-1.2
Had major operations	0.7	0.8	2.2	1.5	0.6	0.7	1.2	1.1	-1.1	1.0	1.1	0.5	0.5	0.6	1.2	1.1	0.6	0.3	0.5	1.2	0.8	0.9	0.3	0.4	1.2	1.0	1.0
Smoking status: Current	0.7	1.2	2.8	-0.0	-1.0	-1.4	-0.8	-0.8	-1.3	-1.1	-0.9	-1.4	-1.7	-1.1	-0.8	-0.9	-1.4	-1.2	-1.4	-0.5	-1.2	-1.4	-1.4	-0.5	-0.8	-1.0	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	3.3	-0.9	-0.9	-0.8	-0.5	-0.5	-1.6	-0.5	-0.7	-1.4	-1.3	0.1	-0.4	-0.5	-1.3	-1.2	-1.0	0.0	-1.2	-0.7	-1.8	-0.9	-0.4	-0.6	-0.6
Ulcerative Colitis (UC)	0.6	1.1	3.1	-0.9	-1.3	-0.5	-1.2	-0.8	-0.2	-0.9	-0.7	-1.8	-1.3	-1.5	-0.8	-0.7	-0.6	-0.1	-0.5	-1.7	-1.6	-1.7	-0.2	0.8	-0.8	-0.6	-0.9
Age at First Birth	0.6	0.9	4.2	-1.6	-0.8	-0.9	-0.7	-1.0	-2.0	-0.8	-0.9	-0.7	-0.6	-0.4	-1.0	-0.9	-1.0	-0.9	-0.9	-0.9	-0.8	-0.5	-0.6	-1.0	-1.0	-1.0	-1.1
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.6	0.0	0.7	1.1	1.0	1.0	1.1	0.9	0.9	0.6	0.1	0.4	0.9	1.0	1.3	0.4	1.1	0.6	0.7	0.2	0.4	0.4	0.9	1.1	0.6
Supplements: Zinc	0.6	0.6	4.8	0.3	0.5	0.7	0.3	0.4	0.7	0.2	0.4	0.5	0.4	-0.7	0.4	0.5	1.3	0.3	0.9	2.2	0.5	1.1	0.8	1.4	0.4	0.3	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	3.2	-0.4	0.7	1.0	0.7	0.7	0.3	0.7	0.9	0.4	0.8	-0.0	0.7	0.8	0.8	1.1	1.0	0.7	0.5	0.6	1.4	1.8	0.7	0.8	0.5
Medication: Ibuprofen	0.6	0.7	3.6	-0.6	-1.0	-0.9	-0.6	-0.4	0.2	-0.6	-0.7	-1.5	-0.9	-0.4	-0.3	-0.5	-1.6	-0.4	-1.1	-0.6	-1.2	-0.7	-1.9	-0.2	-0.3	-0.6	0.3
Whole body water mass	0.6	3.3	8.3	0.8	1.4	2.0	1.9	1.6	2.8	1.5	1.9	0.8	1.4	-0.2	1.6	1.7	2.7	0.6	2.2	2.7	1.1	2.2	2.9	2.2	1.6	1.5	-0.1
Supplements: Calcium	0.6	0.7	3.2	-1.3	-0.9	-0.3	-0.6	-0.5	-0.4	-0.7	-0.6	-1.8	-0.8	-1.5	-0.4	-0.4	-0.5	-0.5	-0.4	0.4	-1.3	-0.3	-1.1	0.9	-0.4	-0.5	-0.6
LDL Cholesterol	0.5	0.9	3.1	0.1	0.9	1.2	0.8	0.8	1.8	0.5	0.9	0.9	1.0	0.1	0.7	0.8	1.3	1.1	1.2	-0.3	0.8	-0.0	1.4	0.8	0.7	0.9	1.0
Sitting height	0.5	3.3	16.4	0.5	1.1	1.8	1.5	1.3	4.0	0.9	1.6	0.4	0.9	-1.7	1.4	1.5	2.9	0.3	2.1	3.2	0.8	1.7	2.6	2.5	1.4	1.2	-0.0
Ever highly irritable/argumentative for 2 days	0.5	0.6	3.1	-0.6	-0.9	-0.8	-0.5	-0.3	-0.1	-0.3	-0.5	-1.7	-0.9	-0.5	-0.3	-0.4	-1.0	-1.0	-0.8	1.2	-1.3	0.7	-0.8	0.5	-0.3	-0.7	-1.0
Blood clot in the leg (DVT)	0.5	0.7	2.6	-0.6	-0.7	-0.7	-0.4	-0.4	-1.6	-0.4	-0.5	-1.2	-1.0	0.2	-0.4	-0.4	-1.2	-1.0	-0.9	-0.2	-1.0	-0.8	-1.5	-1.0	-0.4	-0.4	-0.4
Medication: Blood pressure	0.5	0.8	2.7	0.5	1.0	0.9	0.8	0.9	0.3	0.9	0.7	1.3	1.1	1.0	0.9	0.9	1.0	1.3	0.9	-0.3	1.2	0.3	0.1	0.2	0.9	1.0	1.6
Whole body fat-free mass	0.5	3.1	8.0	0.7	1.3	2.0	1.9	1.6	2.7	1.5	1.9	0.7	1.4	-0.2	1.5	1.7	2.6	0.6	2.2	2.7	1.0	2.2	2.8	2.1	1.5	1.5	-0.1
Medication: Atorvastatin	0.5	0.6	2.4	0.2	0.4	0.4	0.6	0.8	-1.2	0.8	0.6	0.1	1.0	1.2	0.8	0.7	-0.6	0.5	0.2	1.5	0.3	1.5	0.1	1.1	0.8	0.5	0.8
Schizophrenia vs Biploar Disorder	0.4	0.5	1.0	-0.5	-0.9	-0.6	-0.7	-0.9	-0.2	-0.8	-0.7	-0.9	-0.5	-0.5	-0.8	-0.8	-0.6	-0.5	-0.5	-0.7	-1.0	-1.0	-0.1	-0.3	-0.8	-0.7	-0.5
Hand grip strength (left)	0.4	1.1	2.5	-0.7	-1.0	-1.1	-1.2	-1.3	0.8	-1.2	-1.0	-0.8	-0.9	-1.2	-1.2	-1.2	-0.9	-1.5	-1.0	-0.3	-0.9	-0.6	0.0	-0.8	-1.2	-1.3	-1.6
Systolic blood pressure, automated reading	0.4	1.0	3.3	-1.0	-0.9	0.3	-1.0	-1.1	-1.6	-1.0	-0.7	-1.2	-0.2	-1.6	-1.1	-0.8	0.3	-0.1	0.5	-1.8	-1.2	-1.5	0.8	0.2	-1.1	-0.5	-1.0
Medication for hormone replacement therapy	0.4	0.4	2.3	-0.1	0.3	0.8	0.6	0.4	-0.3	0.3	0.6	-0.1	0.4	-0.6	0.4	0.5	0.9	0.9	0.9	0.2	0.1	0.1	1.1	1.5	0.4	0.6	0.2
Vitamin and mineral supplements	0.4	0.5	2.1	0.0	0.8	0.4	0.7	0.6	-0.9	0.7	0.7	1.5	0.5	1.1	0.6	0.6	0.3	0.8	0.4	0.2	1.2	0.1	0.7	0.1	0.6	0.7	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	2.1	-0.5	-0.8	-0.5	-0.4	-0.3	-0.1	-0.5	-0.4	-1.2	-1.4	-1.5	-0.4	-0.4	-0.1	-1.3	-0.4	0.5	-1.0	-0.3	-0.4	-0.3	-0.4	-0.5	-1.2
Time employed in main current job	0.4	0.5	1.7	-0.4	0.7	0.7	0.6	0.7	-1.3	0.7	0.7	0.6	0.5	0.5	0.7	0.7	0.5	0.8	0.7	0.3	0.6	0.2	0.6	0.7	0.7	0.8	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.5	-0.6	-0.9	-0.7	-0.5	-0.3	0.2	-0.5	-0.5	-1.4	-0.7	-0.3	-0.3	-0.4	-1.3	-0.2	-0.9	-0.7	-1.1	-0.7	-1.6	-0.2	-0.3	-0.4	0.4
Exposure to tobacco smoke outside home	0.4	0.5	2.0	-0.5	-0.8	-0.8	-0.6	-0.6	-0.1	-0.7	-0.6	-0.7	-0.7	-0.7	-0.6	-0.6	-0.8	-0.1	-0.8	-1.4	-0.7	-1.3	-0.5	-0.2	-0.6	-0.5	0.3
Comparative body size at age 10	0.4	1.1	4.4	-0.2	-0.8	-1.1	-0.9	-1.1	-2.1	-0.8	-1.0	-0.3	-0.1	0.1	-1.1	-1.1	-1.8	-0.8	-1.2	0.1	-0.5	0.8	-0.3	-0.6	-1.1	-1.3	-1.8
Eye problems/disorders: None of the above	0.4	0.4	5.7	-1.3	-0.2	-0.4	-0.2	-0.1	2.4	-0.5	-0.2	-0.1	-0.3	-0.9	-0.2	-0.2	-0.2	-0.0	-0.4	0.0	-0.1	-0.4	0.0	0.5	-0.2	-0.3	0.3
Supplements: Vitamin C	0.4	0.4	0.9	0.9	-0.8	-0.4	-0.8	-0.8	0.9	-0.7	-0.7	-0.6	-0.3	-0.9	-0.8	-0.7	-0.3	-0.6	-0.3	-0.4	-0.6	-0.2	-0.1	-0.4	-0.8	-0.7	-0.9
Long-standing illness, disability or infirmity	0.4	0.6	1.9	0.6	0.7	0.8	0.9	1.0	0.8	1.0	0.8	0.2	0.3	1.0	0.9	0.9	0.8	-0.1	0.7	1.4	0.5	1.1	-0.2	-0.3	0.9	0.8	0.3
Commuting to job workplace: Walk	0.4	0.4	3.4	-0.5	-0.1	-0.6	-0.7	-0.4	1.8	-0.5	-0.7	0.2	-0.5	-0.5	-0.4	-0.4	-0.2	-0.8	-0.5	0.4	0.1	-0.0	-1.1	-1.0	-0.4	-0.6	-0.4
Medication: Aspirin	0.4	0.5	2.1	0.9	0.8	0.5	0.5	0.6	0.1	0.8	0.4	1.0	0.7	1.5	0.6	0.6	0.2	0.9	0.4	-0.4	0.9	0.3	-0.2	-0.2	0.6	0.7	0.9
Miserableness	0.4	0.8	1.8	-1.1	-1.0	-0.8	-0.7	-0.7	0.7	-0.8	-0.8	-1.2	-1.3	-1.0	-0.7	-0.8	-0.6	-1.4	-0.8	-0.1	-1.1	-0.9	-0.8	-0.9	-0.7	-0.8	-0.7
Supplements: Fish oil (including cod liver oil)	0.4	0.5	4.5	2.1	0.5	0.5	0.6	0.6	0.4	0.7	0.6	0.3	0.7	0.8	0.7	0.6	0.2	0.6	0.5	0.8	0.5	1.2	0.2	0.4	0.7	0.5	0.1
Number of operations (self-reported)	0.4	0.5	2.2	1.3	-0.4	-0.7	-0.2	-0.5	-1.3	-0.2	-0.5	-0.1	-0.1	0.8	-0.4	-0.5	-1.1	-0.7	-0.9	-0.4	-0.2	0.4	-1.2	-1.5	-0.4	-0.6	-0.3
Depressed Affect (Nagel 2018)	0.3	0.7	1.7	-1.3	-0.9	-0.7	-0.8	-0.8	-0.6	-0.7	-0.8	-0.9	-1.1	-0.7	-0.8	-0.8	-0.6	-1.1	-0.7	-0.3	-0.9	-0.7	-0.8	-0.7	-0.8	-0.8	-1.1
Worry (Nagel 2018)	0.3	0.6	2.8	-1.7	-0.7	-0.7	-0.7	-0.7	0.1	-0.7	-0.7	-0.5	-0.9	-0.6	-0.8	-0.8	-0.4	-1.0	-0.6	-0.8	-0.7	-1.0	-0.3	-0.9	-0.8	-0.7	-0.8
Alzheimer’s Disease (including proxy)	0.3	0.4	2.2	0.3	0.6	0.7	0.3	0.6	0.3	0.7	0.4	0.5	0.9	0.9	0.5	0.5	0.4	0.2	0.7	1.1	0.5	1.5	0.2	0.3	0.5	0.4	-0.3
Bipolar Disorder (2011)	0.3	0.3	1.6	-1.2	-0.5	0.1	-0.4	-0.5	1.3	-0.3	-0.2	-0.6	0.0	-0.9	-0.4	-0.3	0.2	-0.4	0.2	0.3	-0.6	0.2	0.6	0.5	-0.4	-0.3	-1.0
Fasting Glucose	0.3	0.4	2.4	0.0	0.4	0.5	0.3	0.7	-1.5	0.0	0.3	-0.6	0.7	0.2	0.2	0.2	0.3	0.4	0.7	1.1	-0.4	0.7	0.6	1.3	0.2	0.4	0.4
Height	0.3	5.0	33.2	-0.7	-1.3	-0.4	-0.9	-1.1	5.8	-1.7	-0.7	-1.9	-1.6	-5.1	-1.1	-1.0	1.7	-3.0	0.2	3.4	-1.5	1.1	1.1	1.1	-1.1	-1.6	-3.4
Townsend deprivation index at recruitment	0.3	0.5	2.3	-0.4	-0.8	-0.9	-0.3	-0.2	-0.2	-0.5	-0.4	-0.9	-0.9	-0.6	-0.2	-0.4	-1.2	-0.9	-1.1	-0.1	-0.7	-0.3	-1.5	-0.5	-0.2	-0.6	0.1
Average weekly fortified wine intake	0.3	0.4	1.4	0.6	-0.3	-0.6	-0.5	-0.5	-0.3	-0.2	-0.6	-0.3	-0.3	0.4	-0.4	-0.5	-0.8	-0.6	-0.7	-0.3	-0.3	0.2	-1.0	-1.1	-0.4	-0.6	-1.2
Pain all over the body in last month	0.3	0.3	1.0	-0.8	-0.7	-0.2	-0.4	-0.5	-0.3	-0.5	-0.5	-0.6	-0.7	-0.6	-0.5	-0.4	-0.1	-1.0	-0.1	-0.1	-0.6	-0.6	-0.6	-0.9	-0.5	-0.4	-0.9
Medication: Ramipril	0.3	0.3	1.6	0.3	0.5	0.5	0.5	0.5	0.3	0.6	0.5	0.5	0.6	0.3	0.6	0.6	0.7	0.1	0.5	1.3	0.6	1.1	0.0	0.1	0.6	0.4	0.3
Trunk fat-free mass	0.3	1.4	7.1	0.5	0.8	1.1	1.0	0.8	2.7	0.7	1.0	0.4	0.7	-0.6	0.7	0.8	1.9	-0.2	1.4	2.1	0.6	1.5	2.1	1.1	0.7	0.7	-0.8
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	2.0	-1.1	-0.6	-0.0	-0.1	-0.2	1.1	-0.3	-0.2	-1.0	-1.1	-0.9	-0.2	-0.2	0.3	-0.7	0.0	-0.7	-0.8	-1.4	-0.2	-0.5	-0.2	-0.0	-0.4
Pulse wave Arterial Stiffness index	0.3	0.4	1.6	0.2	-0.4	-0.4	-0.3	-0.3	1.1	-0.4	-0.4	-0.5	-0.8	-1.1	-0.3	-0.3	0.1	-1.1	-0.3	1.2	-0.4	0.3	-0.6	-0.2	-0.3	-0.6	-1.0
Trunk predicted mass	0.3	1.6	7.4	0.6	0.9	1.2	1.1	0.9	2.7	0.8	1.1	0.5	0.8	-0.6	0.8	0.9	2.0	-0.1	1.5	2.1	0.7	1.6	2.1	1.2	0.8	0.8	-0.6
Tense / ‘highly strung’	0.3	0.6	1.3	-0.4	-0.8	-0.9	-0.7	-0.8	0.3	-1.0	-0.8	-0.3	-0.8	-0.6	-0.8	-0.8	-0.6	-1.1	-0.8	-0.1	-0.5	-0.8	-0.5	-1.0	-0.8	-0.9	-0.6
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.6	0.2	-0.3	-0.9	0.1	-0.0	-0.7	-0.0	-0.3	-0.4	-0.5	0.6	-0.0	-0.2	-1.2	-0.6	-1.1	1.1	-0.3	0.6	-1.1	-0.3	-0.0	-0.4	0.4
Forced vital capacity (FVC), Best measure	0.3	1.1	2.6	-1.5	-0.9	-1.4	-1.0	-1.1	1.3	-1.3	-0.9	-0.3	-1.1	-1.5	-1.0	-1.1	-0.7	-1.6	-1.3	0.5	-0.5	-0.3	-0.4	-0.7	-1.0	-1.3	-1.2
Health satisfaction	0.3	0.4	2.0	-0.4	-0.3	0.6	0.6	0.4	-0.5	0.5	0.5	-1.4	-0.2	-0.7	0.4	0.5	0.5	0.0	0.6	1.0	-0.8	0.4	0.7	1.4	0.4	0.4	-0.3
Medication for pain relief, constipation, heartburn	0.3	0.5	1.8	-1.1	-0.2	-0.1	-0.6	-0.7	1.0	-0.7	-0.4	0.3	-0.1	-1.3	-0.8	-0.6	0.6	-0.8	0.2	0.3	-0.0	-0.1	1.3	-0.1	-0.8	-0.6	-1.3
Alcohol intake frequency.	0.3	0.6	2.4	0.2	0.8	0.3	0.7	0.9	1.3	0.9	0.5	0.8	0.3	1.5	0.9	0.7	0.2	0.7	0.2	-0.4	0.8	-0.0	-1.0	-0.6	0.9	0.8	1.4
Age at last live birth	0.3	0.5	1.7	-1.3	-0.5	-0.7	-0.4	-0.3	-0.8	-0.4	-0.5	-0.3	-1.1	-0.0	-0.3	-0.4	-0.4	-0.9	-0.7	-0.5	-0.3	-1.2	-1.3	-1.3	-0.3	-0.3	0.1
Ever had bowel cancer screening	0.3	0.4	1.6	-0.7	-0.5	-0.7	-0.6	-0.8	-0.2	-0.6	-0.7	-0.2	-0.1	-0.2	-0.8	-0.8	-0.8	0.0	-0.7	-1.3	-0.5	-0.3	-0.3	-0.3	-0.8	-0.8	-0.3
Friendships satisfaction	0.3	0.4	3.6	-0.4	-0.0	0.3	0.1	0.0	-0.3	0.1	0.3	-0.6	0.4	-0.7	0.0	0.1	0.3	0.6	0.4	0.7	-0.4	0.8	1.5	1.9	0.0	0.0	-0.5
Medication: Paracetamol	0.3	0.5	3.0	0.2	-0.5	-0.7	0.0	0.1	-0.5	0.0	-0.2	-1.1	-1.0	0.5	0.1	-0.1	-1.0	-0.4	-0.9	-0.5	-0.8	-0.7	-1.7	-0.8	0.1	-0.0	0.6
Age started oral contraceptive pill	0.3	0.4	1.5	-0.7	-0.7	-0.6	-0.7	-0.5	-0.7	-0.4	-0.7	-1.1	-0.7	-0.0	-0.5	-0.5	-0.8	-0.7	-0.7	0.3	-0.9	-0.2	-1.2	-0.3	-0.5	-0.6	-0.5
Ever depressed for a whole week	0.3	0.4	2.2	-1.2	-0.8	-0.1	-0.3	-0.1	0.7	-0.3	-0.2	-1.5	-0.8	-1.3	-0.2	-0.2	0.0	-0.6	-0.1	0.2	-1.1	-0.2	-0.1	0.7	-0.2	-0.2	-0.6
Unable to work because of sickness or disability	0.3	0.3	2.2	-0.0	-1.0	-0.2	-0.1	-0.3	-1.0	-0.3	-0.3	-1.5	-0.7	-0.5	-0.2	-0.2	-0.4	-0.6	-0.2	-0.3	-1.1	-0.7	-0.5	-0.2	-0.2	-0.2	-0.1
Alzheimer’s Disease (in mother)	0.2	0.2	0.6	-0.4	0.4	0.7	0.3	0.4	0.5	0.5	0.5	0.3	0.8	0.6	0.4	0.4	0.5	0.1	0.7	0.5	0.3	0.8	0.6	0.4	0.4	0.5	-0.1
Alzheimer’s Disease (in father)	0.2	0.3	1.3	1.1	-0.4	-0.1	-0.2	-0.1	-1.2	0.1	-0.2	-0.7	0.0	0.4	-0.0	-0.1	-0.7	0.1	-0.3	0.3	-0.5	0.9	-0.9	0.3	-0.0	-0.2	-0.3
Ovarian Cancer	0.2	0.3	2.3	-1.0	0.1	0.7	-0.0	-0.1	-0.0	-0.0	0.0	0.4	0.5	0.2	-0.1	0.1	0.6	0.7	0.8	-1.5	0.1	-1.1	0.8	-0.2	-0.1	0.4	0.4
Rheumatoid Arthritis	0.2	0.3	2.1	-0.4	-0.3	0.0	0.1	0.3	1.4	-0.0	0.1	-1.0	-0.4	-0.8	0.3	0.2	0.0	-0.1	-0.0	0.9	-0.5	0.4	-0.4	1.1	0.3	0.0	0.1
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.9	0.2	0.1	0.7	0.3	0.2	0.0	0.2	0.4	0.1	0.0	-0.2	0.3	0.4	0.9	-0.4	0.7	1.0	0.2	-0.2	0.7	-0.2	0.3	0.5	-0.1
Blood Eosinophil Count	0.2	1.4	3.1	0.8	1.1	1.5	1.4	1.1	0.0	1.0	1.4	0.9	1.4	0.5	1.1	1.2	1.5	1.3	1.6	0.3	0.9	0.6	1.8	1.1	1.1	1.3	1.6
Heel T-Score	0.2	1.4	9.1	2.0	0.4	-0.2	0.8	0.8	-3.0	0.9	0.7	-0.2	0.0	1.5	0.9	0.6	-1.4	-0.4	-0.6	2.8	0.2	1.7	-0.3	0.6	0.9	0.4	0.1
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.5	0.6	0.6	0.1	0.3	0.4	-0.3	0.6	0.3	0.7	0.2	1.1	0.4	0.3	0.3	-0.4	0.1	1.2	0.6	1.1	-0.3	-0.6	0.4	0.2	-0.2
Medication: Co-codamol	0.2	0.2	1.2	0.6	-0.4	-0.2	0.2	0.2	0.0	0.1	0.0	-0.9	-0.3	0.3	0.2	0.1	-0.7	0.2	-0.4	-0.6	-0.6	-0.5	-1.1	0.1	0.2	0.2	0.9
Diabetes (father)	0.2	0.2	1.7	1.3	-0.4	-0.3	0.0	-0.1	-0.1	0.1	-0.2	-0.8	-0.3	0.3	-0.1	-0.1	-0.6	-0.7	-0.4	0.7	-0.5	0.5	-0.3	-0.1	-0.1	-0.2	-0.6
Fed-up feelings	0.2	0.3	2.0	-1.4	-0.3	0.3	-0.1	-0.1	0.1	-0.2	-0.0	-0.8	-0.3	-1.3	-0.1	0.0	0.7	-0.3	0.5	0.3	-0.5	-0.1	0.3	0.4	-0.1	-0.0	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.3	1.5	0.5	-0.3	0.4	0.5	-0.8	0.7	0.3	0.6	-0.3	1.3	0.6	0.4	-0.4	-0.4	-0.5	1.4	0.7	0.9	-0.8	-0.8	0.6	0.2	0.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.2	-0.2	-0.4	-0.5	-0.3	-0.5	0.3	-0.4	-0.4	-0.1	-0.2	0.0	-0.5	-0.5	-0.7	-0.7	-0.5	-0.6	-0.3	-0.4	-0.3	-1.1	-0.5	-0.5	-0.3
Chronic bronchitis/emphysema (father)	0.2	0.3	1.1	-0.1	-0.5	-0.6	-0.5	-0.4	0.4	-0.5	-0.6	-0.6	-0.3	-0.7	-0.4	-0.4	-0.7	-0.0	-0.7	-0.4	-0.5	-0.0	-1.1	0.3	-0.4	-0.6	0.1
Alcohol usually taken with meals	0.2	0.3	2.9	0.2	0.0	-0.2	-0.5	-0.3	-1.3	-0.2	-0.4	0.2	0.1	0.5	-0.3	-0.3	-0.5	0.8	-0.2	-1.7	0.0	-0.6	-0.6	-0.1	-0.3	-0.1	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.0	0.8	-0.0	-0.9	-0.3	-0.1	-1.0	-0.1	-0.3	0.2	-0.6	1.0	-0.0	-0.3	-1.2	-0.8	-1.2	0.5	0.1	-0.0	-1.4	-1.4	-0.0	-0.4	-0.1
Heart attack	0.2	0.2	1.3	-1.1	-0.4	-0.1	-0.1	-0.1	0.8	-0.3	-0.1	-0.8	-0.6	-1.0	-0.1	-0.1	0.3	-0.3	-0.0	-0.1	-0.6	-0.6	-0.1	0.4	-0.1	-0.1	-0.2
Number of live births	0.2	0.3	2.2	-0.1	0.2	-0.2	0.3	0.3	-0.7	0.4	0.1	0.3	0.1	1.5	0.3	0.2	-0.5	-0.1	-0.3	-0.1	0.3	0.3	-0.9	-1.2	0.3	0.2	0.5
Happiness	0.2	0.2	0.9	-0.8	-0.5	-0.1	-0.2	-0.2	0.3	-0.3	-0.1	-0.8	-0.2	-0.9	-0.3	-0.3	0.0	-0.3	-0.0	0.1	-0.7	-0.0	0.9	0.4	-0.3	-0.3	-0.7
Birth weight of first child	0.2	0.3	0.8	-0.3	-0.3	-0.6	-0.6	-0.6	0.7	-0.6	-0.6	0.1	-0.7	-0.5	-0.6	-0.6	-0.2	-0.6	-0.5	-0.1	-0.1	-0.4	-0.7	-0.8	-0.6	-0.6	-0.9
Loud music exposure frequency	0.2	0.3	1.8	-0.4	-0.5	0.3	0.3	0.2	0.4	0.1	0.3	-1.3	-0.3	-0.4	0.2	0.2	-0.1	0.3	0.3	-0.3	-1.0	-0.4	0.3	1.3	0.2	0.3	0.3
Medication: Paracetamol	0.2	0.4	3.7	0.2	-0.3	-0.8	0.0	0.2	-0.1	0.1	-0.2	-0.7	-0.6	0.8	0.2	-0.0	-1.0	-0.1	-1.0	-0.3	-0.4	-0.2	-1.9	-0.6	0.2	-0.1	0.8
Pulse wave peak to peak time	0.2	0.2	1.3	-0.2	0.2	0.2	0.2	0.2	-0.9	0.3	0.2	0.4	0.6	0.8	0.1	0.2	-0.2	0.9	0.1	-1.1	0.3	-0.4	0.5	0.1	0.1	0.3	0.8
Number of full sisters	0.2	0.3	1.5	-0.6	-0.2	-0.2	-0.0	-0.2	0.8	-0.3	-0.3	-0.2	-0.8	-0.6	-0.2	-0.2	0.2	-1.1	-0.2	-0.1	-0.2	-0.8	-0.7	-1.2	-0.2	-0.2	-0.1
Overall health rating	0.2	0.5	2.3	-0.4	-0.7	-0.2	0.2	0.1	-1.3	0.1	-0.1	-1.5	-0.9	-0.2	0.2	0.1	-0.5	-1.2	-0.3	0.5	-1.0	-0.1	-1.4	-0.8	0.2	0.0	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.4	-0.2	0.6	-0.0	-0.0	0.2	-0.4	0.4	0.0	1.0	0.6	0.9	0.3	0.2	-0.4	1.2	-0.1	-0.1	0.8	0.7	-0.3	0.8	0.3	0.1	0.3
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	2.2	-0.3	-0.1	-0.2	-0.5	-0.5	0.1	-0.4	-0.4	0.1	0.1	-0.5	-0.5	-0.4	0.1	0.8	-0.1	-1.5	-0.1	-0.7	0.2	0.2	-0.5	-0.3	-0.1
Medication: Aspirin	0.2	0.3	1.8	0.5	0.5	0.1	0.2	0.3	-0.5	0.5	0.1	0.8	0.4	1.3	0.3	0.3	-0.3	0.6	-0.0	-0.4	0.7	-0.0	-0.7	-0.6	0.3	0.4	0.7
Hypertension (Self-reported)	0.2	0.4	1.0	0.6	0.7	0.8	0.5	0.6	-0.5	0.7	0.5	0.7	0.9	0.8	0.6	0.7	0.7	0.8	0.8	-0.5	0.7	0.4	-0.3	-0.3	0.6	0.7	1.0
Illnesses of siblings: Diabetes	0.2	0.3	1.7	0.4	0.6	0.2	0.1	0.3	1.3	0.4	0.2	1.2	0.2	0.6	0.3	0.3	0.5	0.2	0.2	-0.2	0.9	0.0	-0.0	-0.7	0.3	0.3	0.3
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.1	0.2	-0.0	-0.7	-0.3	-0.4	1.1	-0.5	-0.4	0.7	0.0	0.2	-0.4	-0.5	-0.7	0.0	-0.7	-1.0	0.3	-0.5	-0.5	-0.9	-0.4	-0.5	0.7
Breast cancer (self-reported)	0.2	0.2	2.4	0.9	-0.3	0.1	-0.0	-0.1	-1.6	0.1	-0.1	-0.5	-0.0	0.0	-0.1	-0.0	-0.2	0.5	0.0	-0.5	-0.4	-0.1	-0.1	0.7	-0.1	0.0	-0.3
Wears glasses or contact lenses	0.2	0.3	2.3	1.5	-0.1	-0.1	-0.3	0.0	-1.1	0.0	-0.3	-0.3	-0.4	0.2	-0.0	-0.0	-0.6	-0.0	-0.2	-0.0	-0.2	0.1	-1.1	-0.4	-0.0	-0.1	-0.2
Mother’s age at death	0.2	0.3	1.1	-0.3	0.4	0.3	0.5	0.4	0.5	0.4	0.5	0.8	0.6	0.5	0.4	0.4	0.4	0.7	0.3	-0.5	0.6	0.1	0.7	0.1	0.4	0.5	1.1
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.2	-0.4	0.0	0.6	0.3	0.1	1.1	0.3	0.3	-0.2	0.6	-0.2	0.2	0.3	0.5	-0.5	0.7	1.1	-0.0	1.0	0.9	0.1	0.2	0.2	-0.4
Basal cell carcinoma (self-reported)	0.2	0.2	1.0	-0.4	-0.2	0.3	0.2	0.2	-1.0	0.1	0.3	-0.8	-0.1	-0.3	0.2	0.2	-0.3	-0.2	0.2	0.9	-0.5	0.1	0.4	0.8	0.2	0.2	-0.1
Heart attack/myocardial infarction (self-reported)	0.2	0.3	1.6	-1.3	-0.4	-0.2	-0.2	-0.2	0.8	-0.4	-0.2	-0.8	-0.7	-1.1	-0.2	-0.2	0.2	-0.5	-0.1	-0.1	-0.6	-0.7	-0.1	0.2	-0.2	-0.2	-0.4
Depression (Nagel 2018)	0.1	0.2	1.7	-0.3	0.1	-0.0	0.1	0.2	0.3	0.2	0.1	-0.3	-0.7	-0.2	0.1	0.1	0.3	-1.0	0.0	1.3	-0.1	0.4	-0.2	-0.5	0.1	-0.0	-1.1
Body Mass Index (BMI) (2010)	0.1	0.1	0.8	-0.7	-0.2	0.4	0.1	-0.1	0.9	0.1	0.3	-0.4	-0.1	-0.6	0.2	0.2	0.5	-0.0	0.5	0.1	-0.2	-0.2	0.5	0.5	0.2	0.3	-0.1
HDL Cholesterol	0.1	0.2	0.5	0.7	0.3	-0.2	0.3	0.5	-0.3	0.3	0.1	0.5	0.2	0.5	0.4	0.2	-0.1	0.6	-0.3	0.0	0.5	0.6	-0.7	0.1	0.4	0.1	0.7
Primary Biliary Cirrhosis	0.1	0.2	0.9	0.3	0.4	0.1	0.2	0.4	-0.3	0.4	0.4	0.5	0.6	0.6	0.4	0.3	-0.2	0.8	0.0	-0.2	0.4	0.2	0.5	0.7	0.4	0.4	1.0
Waist Hip Ratio (WHR)	0.1	0.5	3.2	-0.3	-0.4	-0.5	-0.5	-0.3	-1.8	-0.3	-0.4	-0.4	-0.2	0.5	-0.3	-0.4	-1.2	0.5	-0.7	-1.2	-0.4	-0.6	-1.0	-0.1	-0.3	-0.3	0.6
Cardiovascular Disease	0.1	0.2	1.7	-0.8	-0.0	-0.0	-0.4	-0.2	-0.1	-0.1	-0.3	0.2	-0.0	0.2	-0.1	-0.1	0.1	-0.2	-0.0	-1.2	0.1	-0.6	-1.1	-1.3	-0.1	-0.0	0.3
Lung FVC	0.1	0.3	1.5	0.1	0.6	0.1	0.3	0.2	-1.0	0.2	0.4	1.2	0.7	0.3	0.2	0.2	0.1	0.7	0.1	0.4	0.9	0.3	1.2	0.7	0.2	0.2	0.7
Hair Pigment	0.1	2.2	3.8	1.0	1.7	1.7	1.7	1.5	0.6	1.7	1.6	1.5	1.1	1.2	1.6	1.6	1.6	0.9	1.7	2.0	1.6	1.3	1.4	1.2	1.6	1.7	1.0
Number of treatments/medications taken	0.1	0.1	0.2	0.3	0.2	0.4	0.4	0.4	-0.1	0.4	0.3	-0.2	0.1	0.4	0.4	0.4	0.1	0.4	0.4	-0.1	-0.0	-0.1	-0.5	0.2	0.4	0.5	0.3
Hand grip strength (right)	0.1	0.3	2.2	-0.9	-0.4	-0.2	-0.4	-0.4	1.5	-0.4	-0.2	-0.6	-0.4	-1.1	-0.4	-0.3	0.1	-0.5	-0.2	0.1	-0.5	-0.1	0.5	0.4	-0.4	-0.4	-0.8
Taking other prescription medications	0.1	0.2	1.1	0.3	-0.2	-0.4	-0.3	-0.1	1.0	-0.1	-0.3	-0.3	-0.5	0.1	-0.1	-0.2	-0.4	-0.2	-0.4	-0.3	-0.2	-0.1	-1.0	-0.5	-0.1	-0.2	-0.1
High blood pressure	0.1	0.2	0.7	0.5	0.3	0.5	0.1	0.2	-0.8	0.4	0.1	0.2	0.5	0.5	0.3	0.3	0.3	0.4	0.5	-0.7	0.2	0.1	-0.6	-0.5	0.3	0.4	0.6
Nervous feelings	0.1	0.2	2.0	-1.4	0.2	0.4	-0.0	0.0	1.1	-0.1	0.1	0.2	-0.0	-0.5	0.0	0.1	0.8	-0.2	0.5	-0.1	0.1	-0.4	0.3	-0.3	0.0	0.2	-0.1
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.4	-0.0	0.0	0.3	0.0	0.2	0.2	0.3	0.2	-0.4	0.1	-0.0	0.2	0.2	0.1	0.1	0.3	0.5	-0.1	0.6	0.1	0.4	0.2	0.2	-0.3
Lung cancer (father)	0.1	0.2	1.0	-0.5	0.3	-0.1	0.2	0.2	0.5	0.2	0.1	0.5	0.2	0.4	0.1	0.1	0.4	0.7	0.0	-1.0	0.4	-0.3	0.1	-0.2	0.1	0.2	0.8
Medication: Amlodipine	0.1	0.2	1.2	-1.0	0.2	0.5	0.2	0.2	1.1	0.1	0.3	0.4	0.4	-0.3	0.2	0.3	0.7	0.5	0.5	-0.4	0.3	-0.1	0.6	0.2	0.2	0.3	0.5
Medication: Ventolin 100micrograms inhaler	0.1	0.2	1.0	-0.2	0.0	-0.1	0.1	-0.0	-1.0	-0.2	-0.0	0.0	-0.4	-0.5	-0.0	-0.1	-0.1	-0.7	-0.1	1.0	0.0	0.2	0.1	-0.2	-0.0	-0.2	-0.7
Age at first live birth	0.1	0.2	2.1	-0.4	0.1	0.3	0.2	0.3	-1.5	0.4	0.2	-0.0	0.0	0.5	0.3	0.3	0.2	0.7	0.3	-0.8	-0.0	-0.6	0.1	0.2	0.3	0.5	0.7
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.3	-0.0	0.2	-0.0	-0.4	-0.2	0.0	-0.1	-0.3	0.5	0.4	0.4	-0.2	-0.2	-0.1	0.6	-0.0	-0.3	0.3	0.3	-0.4	0.2	-0.2	-0.2	0.1
Suffer from ‘nerves’	0.1	0.2	1.2	-1.1	-0.3	-0.2	-0.2	-0.1	1.1	-0.3	-0.1	-0.6	-0.8	-0.8	-0.1	-0.1	0.1	-0.4	-0.2	0.5	-0.5	-0.4	-0.1	0.4	-0.1	-0.1	-0.3
Family relationship satisfaction	0.1	0.1	0.3	-0.4	-0.0	-0.4	-0.3	-0.2	0.1	-0.2	-0.3	-0.2	-0.2	-0.3	-0.2	-0.3	-0.2	0.2	-0.3	0.2	-0.2	0.2	0.0	0.6	-0.2	-0.4	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	1.1	0.1	-0.2	-0.0	0.1	0.1	-0.1	-0.3	-0.0	-0.5	-0.3	-0.6	0.0	-0.0	0.2	0.2	-0.0	-0.9	-0.4	-1.0	-0.4	0.1	0.0	0.1	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.9	-0.7	0.2	-0.2	-0.2	-0.2	-0.1	-0.1	-0.2	0.9	0.2	0.2	-0.2	-0.2	0.2	-0.4	-0.1	0.9	0.6	0.9	0.2	-0.4	-0.2	-0.4	-0.9
Number of self-reported non-cancer illnesses	0.1	0.3	1.2	0.3	-0.3	-0.2	-0.4	-0.4	-1.1	-0.2	-0.5	-0.3	-0.3	-0.0	-0.3	-0.3	-0.3	-0.8	-0.2	0.2	-0.3	0.4	-0.9	-0.8	-0.3	-0.4	-0.9
Average weekly champagne plus white wine intake	0.1	0.1	0.7	-0.6	-0.1	0.0	-0.1	-0.2	0.7	-0.1	-0.1	0.1	-0.3	-0.2	-0.2	-0.1	0.1	0.1	0.1	0.6	0.0	0.1	0.4	0.9	-0.2	-0.1	-0.7
Myopia	0.1	0.2	0.8	0.7	0.4	0.1	0.3	0.3	-0.6	0.4	0.3	0.8	0.5	0.9	0.3	0.2	-0.3	0.2	-0.1	0.4	0.7	0.4	0.3	-0.3	0.3	0.3	0.6
Tanning	0.0	0.1	0.3	0.1	-0.1	-0.4	-0.3	-0.4	0.5	-0.5	-0.1	0.0	0.3	-0.3	-0.3	-0.3	-0.5	-0.0	-0.4	-0.6	-0.1	-0.4	0.3	0.2	-0.3	-0.4	-0.2
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.6	-0.1	-0.0	-0.1	0.2	0.1	0.7	-0.1	0.2	-0.0	-0.2	-0.4	0.0	-0.0	-0.1	-0.1	-0.1	0.8	-0.0	0.0	0.8	0.7	0.0	-0.0	-0.3