Best TWAS P=7.04e-10 · Best GWAS P=2.74e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LNX1 | 0.03 | 0.02 | blup | 178 | 0.02 | 1.5e-05 | -4.9 | -5.3 | 1.5e-07 | 0.07 | 0.42 | 0.07 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SCFD2 | 0.07 | 0.06 | lasso | 2 | 0.05 | 7.0e-06 | -6.3 | 6.2 | 7.0e-10 | -0.98 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FIP1L1 | 0.03 | 0.04 | lasso | 3 | 0.04 | 9.3e-05 | -6.3 | -5.8 | 6.0e-09 | 0.98 | 0.01 | 0.98 | FALSE |